1,4-Cyclohexanediol supplier

Name
1,4-Cyclohexanediol
EINECS 209-126-2
CAS No. 556-48-9
Article Data69
CAS DataBase
Density 1.156 g/cm³
Solubility It is highly soluble in water.
Melting Point 98-100 °C(lit.)
Formula C₆H₁₂O₂
Boiling Point 252.4 °C at 760 mmHg
Molecular Weight 116.16
Flash Point 65.6 °C
Transport Information UN 1325
Appearance white to off-white crystalline powder
Safety 24/25
Risk Codes Xi
Molecular Structure
Hazard Symbols Xi
Synonyms 1,4-Dihydroxycyclohexane;NSC 5651;Quinitol;1,4-Cyclohexanediol(Mixture of Cis and Trans);cyclohexane-1,4-diol;
PSA 40.46000
LogP 0.28220

Synthetic route

: 123-31-9
hydroquinone

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With hydrogen In water at 30℃; under 7500.75 Torr; for 7h; Autoclave;	99.1%
With hydrogen In water at 80℃; under 15001.5 Torr; for 6h;	99%
With potassium hydroxide; samarium diiodide In tetrahydrofuran; water for 0.05h; Ambient temperature;	98%

: 637-88-7
1,4-Cyclohexanedione

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With samarium diiodide; water In tetrahydrofuran at 20℃;	99%
With sodium tetrahydroborate; TiO(acac)2 In tetrahydrofuran for 0.17h; Heating;	93%
With sodium tetrahydroborate; Dowex1-x8 In tetrahydrofuran for 0.34h; Heating;	90%

: 103-16-2
4-Benzyloxyphenol

A: 556-48-9
1,4-Cyclohexanediol

B: 108-88-3
toluene

Conditions

Conditions	Yield
With hydrogen In n-heptane at 140℃; under 750.075 Torr; for 6h; Catalytic behavior;	A 99% B 99%

: 1036648-32-4
(4-hydroxycyclohexyl) 4-methylbenzoate

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With methanol; samarium diiodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide Reflux;	98%
With methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide In tetrahydrofuran Inert atmosphere; Reflux;	98%

: 55724-30-6
1,4-bis-trimethylsiloxycyclohexane

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With water; p-toluenesulfonyl chloride at 20℃; for 0.0833333h;	91%
With aminosulfonic acid; water at 20℃; for 4.5h;	91%
With water; boric acid at 20℃; for 24h;	85%

: 1163693-65-9
4-(4-methylbenzoyloxy)cyclohexyl 4-(trifluoromethyl)benzoate

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With tetrabutylammonium tetrafluoroborate In 1-methyl-pyrrolidin-2-one; isopropyl alcohol at 90℃; Electrochemical reaction;	65%

1,4-cyclohexanedione(tetrahydroquinone): 1,4-cyclohexanedione(tetrahydroquinone)

: 637-88-7
1,4-Cyclohexanedione

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
In isopropyl alcohol	53%

: 1965-09-9
4,4'-dihydroxydiphenyl ether

A: 110-82-7
cyclohexane

B: 556-48-9
1,4-Cyclohexanediol

C: 108-93-0
cyclohexanol

Conditions

Conditions	Yield
With isopropyl alcohol at 150℃; for 6h; Sealed tube;	A 10.5 %Chromat. B 8.4% C 76.2 %Chromat.

...Expand

: 637-88-7
1,4-Cyclohexanedione

A: 556-48-9
1,4-Cyclohexanediol

B: 6995-79-5
cyclohexane-1,4-diol

Conditions

Conditions	Yield
With water; sodium hydrogencarbonate unter Durchleiten von CO2; cis-quinitol;

: 53762-85-9
(1S,4R)-Cyclohex-2-ene-1,4-diol

A: 30182-12-8
4-hydroxy-2-cyclohexenone

B: 556-48-9
1,4-Cyclohexanediol

C: 13482-22-9
4-hydroxycyclohexanone

Conditions

Conditions	Yield
ruthenium In tetrahydrofuran at 65℃; for 15h; Yield given. Yields of byproduct given;
ruthenium In tetrahydrofuran at 60℃; for 15h; Yield given. Yields of byproduct given;

...Expand

: 13482-22-9
4-hydroxycyclohexanone

A: 556-48-9
1,4-Cyclohexanediol

B: 108-94-1
cyclohexanone

C: 108-93-0
cyclohexanol

Conditions

Conditions	Yield
With hydrogen; palladium In tert-butyl alcohol at 30℃; Yield given. Yields of byproduct given;
With hydrogen; palladium In tert-butyl alcohol at 30℃; Product distribution; further catalyst, further 4-substituted cyclohexanone;

...Expand

: 75-07-0
acetaldehyde

: 1165952-91-9
cyclohexa-1,3-diene

A: 931-17-9
1,2-Cyclohexanediol

B: 504-01-8
cyclohexane-1,3-diol

C: 556-48-9
1,4-Cyclohexanediol

D: 40391-19-3
(1R*,1'RS*)-1-cyclohex-2-enylethanol

E: 822-66-2, 72137-22-5
3-cyclohexen-1-ol

Conditions

Conditions	Yield
With sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide Product distribution; other cyclic dienes and hydroborating agents;

...Expand

: 637-88-7
1,4-Cyclohexanedione

A: 556-48-9
1,4-Cyclohexanediol

B: 13482-22-9
4-hydroxycyclohexanone

Conditions

Conditions	Yield
With hydrogen; silica gel; nickel In isopropyl alcohol at 100℃; under 4650.4 Torr; Product distribution; Kinetics; various catalyst, var. temp., var. of hydrogen pressure, var. of substrate concentr.;	A n/a B 87 % Chromat.
With hydrogen; palladium/alumina at 130℃; under 22502.3 Torr; Conversion of starting material;
With Zr -F-100 In isopropyl alcohol at 82℃; for 6h; Reagent/catalyst;
With nicotinamide adenine dinucleotide phosphate; isopropyl alcohol In aq. phosphate buffer at 30℃; for 12h; pH=7; Enzymatic reaction;

: 637-88-7
1,4-Cyclohexanedione

A: 556-48-9
1,4-Cyclohexanediol

B: 13482-22-9
4-hydroxycyclohexanone

C: 108-94-1
cyclohexanone

D: 108-93-0
cyclohexanol

Conditions

Conditions	Yield
With hydrogen; palladium In tert-butyl alcohol at 30℃; Product distribution; further catalyst;
With hydrogen; palladium In tert-butyl alcohol at 30℃; Yield given. Yields of byproduct given;

...Expand

: 123-31-9
hydroquinone

compressed hydrogen: compressed hydrogen

nickel: nickel

: 556-48-9
1,4-Cyclohexanediol

...Expand

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B cis-quinitol, cyclohexanol, phenol: cis-quinitol, cyclohexanol, phenol

Conditions

Conditions	Yield
With hydrogen; nickel at 170℃; trans-quinitol;

: 108-94-1
cyclohexanone

A: 124-04-9
Adipic acid

B: 110-15-6
succinic acid

C: 556-48-9
1,4-Cyclohexanediol

D: 637-88-7
1,4-Cyclohexanedione

Conditions

Conditions	Yield
With peracetic acid; Ru-carbon In ethyl acetate at 20℃; for 1h; Further byproducts given;	A 48 % Chromat. B 26 % Chromat. C n/a D 8 % Chromat.

...Expand

: 787-07-5
diethyl 1,4-cyclohexanedione-2,5-dicarboxylate

: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: concentrated sulfuric acid View Scheme
Multi-step reaction with 2 steps 1: concentrated sulfuric acid 2: NaHCO3; water / unter Durchleiten von CO2 View Scheme

: 67-56-1
methanol

Reaxys ID: 11384307: Reaxys ID: 11384307

A: 542-28-9
3,4,5,6-tetrahydro-2H-pyran-2-one

B: 627-93-0
hexanedioic acid dimethyl ester

C: 4547-43-7
methyl 6-hydroxycaproate

D: 1119-40-0
Dimethyl glutarate

E: 14273-92-8
methyl 5-hydroxypentanoate

F: 931-17-9
1,2-Cyclohexanediol

G: 556-48-9
1,4-Cyclohexanediol

H: 106-65-0
Dimethyl succinate

Conditions

Conditions	Yield
With sulfuric acid

...Expand

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B: 13482-22-9
4-hydroxycyclohexanone

C: 637-88-7
1,4-Cyclohexanedione

Conditions

Conditions	Yield
With hydrogen; Pd/hydrophilic-C at 100℃; under 7500.75 Torr; for 20h;

...Expand

: 110-82-7
cyclohexane

A: 124-04-9
Adipic acid

B: 1191-25-9
6-Hydroxyhexanoic acid

C: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With oxygen at 160℃; under 7500.75 Torr;

...Expand

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B: 13482-22-9
4-hydroxycyclohexanone

Conditions

Conditions	Yield
With carbon dioxide; hydrogen at 50℃; under 30003 - 90009 Torr; for 4h; Supercritical conditions;
With hydrogen In water at 25℃; under 750.075 Torr; for 7h; Autoclave;
With hydrogen In dichloromethane at 50℃; under 7500.75 Torr; for 1h;

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B: 108-93-0
cyclohexanol

C: 108-95-2
phenol

Conditions

Conditions	Yield
With hydrogen In ethanol at 160℃; under 11251.1 Torr;

...Expand

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B: 108-95-2
phenol

Conditions

Conditions	Yield
With hydrogen In ethanol at 160℃; under 11251.1 Torr;

: 1524-19-2
4-(4-fluorophenoxy)phenol

A: 462-06-6
fluorobenzene

B: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With rhodium contaminated with carbon; water; hydrogen at 80℃; for 18h; Supercritical conditions; Autoclave;

: 831-82-3
4-Phenoxyphenol

A: 556-48-9
1,4-Cyclohexanediol

B: 1526806-99-4
C12H16O2

C: 71-43-2
benzene

Conditions

Conditions	Yield
With hydrogen In ethanol at 150℃; under 9000.9 Torr;

...Expand

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B: 637-88-7
1,4-Cyclohexanedione

C: 108-95-2
phenol

Conditions

Conditions	Yield
With hydrogen In water at 119.84℃; under 4500.45 Torr; Kinetics;

...Expand

: 123-31-9
hydroquinone

A: 556-48-9
1,4-Cyclohexanediol

B: 13482-22-9
4-hydroxycyclohexanone

C: 108-94-1
cyclohexanone

D: 108-93-0
cyclohexanol

Conditions

Conditions	Yield
With hydrogen In water at 25℃; under 760.051 Torr; for 15h; Schlenk technique; Green chemistry;

...Expand

: 110-82-7
cyclohexane

A: 504-01-8
cyclohexane-1,3-diol

B: 556-48-9
1,4-Cyclohexanediol

Conditions

Conditions	Yield
With [Cu3(μ3-5-(4-pyridyl)tetrazolate)4(μ2-N3)2(DMF)2]n·(DMF)2n; dihydrogen peroxide In neat (no solvent) at 20℃; under 760.051 Torr; for 24h; Green chemistry;

: 556-48-9
1,4-Cyclohexanediol

: 131832-07-0, 131832-10-5
1,4-cyclohexanediol-O,O-d2

Conditions

Conditions	Yield
With water-d2 for 6h; Ambient temperature;	99%

: 556-48-9
1,4-Cyclohexanediol

: 98-88-4
benzoyl chloride

: 6308-92-5
4-benzoyloxycyclohexanol

Conditions

Conditions	Yield
With triethylamine In dichloromethane	99%
With pyridine; dmap In dichloromethane at 25℃; for 4h;	30%
With pyridine In dichloromethane at 25℃; for 4h;	30%
With pyridine In chloroform at 0 - 20℃; for 6h;

: 556-48-9
1,4-Cyclohexanediol

: 105-58-8
Diethyl carbonate

: 1,4-bis(ethoxycarbonyloxy)cyclohexane

Conditions

Conditions	Yield
With MgLa mixed oxides at 129.85℃; for 0.75h;	98%
aluminum oxide; cesium fluoride at 129.85℃; for 0.5h;	97%
With MgLa mixed oxide at 125℃; for 0.75h;	97%
With immobilized 1,5,7-triazabicyclo[4.4.0]dec-5-ene on magnetic γ-Fe2O3 nanoparticles at 125℃; for 10h;	94%

: 556-48-9
1,4-Cyclohexanediol

: 637-88-7
1,4-Cyclohexanedione

Conditions

Conditions	Yield
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In neat (no solvent) at 20℃; for 1h; Milling;	97%
With ruthenium(IV) oxide; sodium dihydrogenphosphate; sodium chloride In water at 10 - 15℃; electrooxidation;	94%
With m-iodosylbenzoic acid; ruthenium trichloride In water; acetonitrile at 20℃; for 10h;	84%

: 556-48-9
1,4-Cyclohexanediol

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 55724-30-6
1,4-bis-trimethylsiloxycyclohexane

Conditions

Conditions	Yield
iodine In dichloromethane at 20℃; for 0.0666667h; Substitution;	97%
With boric acid In acetonitrile at 20℃; for 2h;	97%
With aminosulfonic acid In acetonitrile at 20℃; for 2h;	95%
Stage #1: 1,4-Cyclohexanediol With Iron(III) nitrate nonahydrate; sodium iodide In dichloromethane at 20℃; Stage #2: 1,1,1,3,3,3-hexamethyl-disilazane In dichloromethane at 20℃; for 0.0416667h;	90%
With p-toluenesulfonyl chloride In dichloromethane at 20℃; for 0.5h;	85%

: 556-48-9
1,4-Cyclohexanediol

: 30485-71-3
4-chlorocyclohexanol

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; N,N-dimethyl-formamide In dichloromethane at 25℃; for 0.25h;	95%
With hydrogenchloride at 100℃; im geschlossenen Gefaess;
With hydrogenchloride

: 556-48-9
1,4-Cyclohexanediol

: 108-24-7
acetic anhydride

: 6289-83-4, 42742-00-7, 19843-75-5
1,4-diacetoxycyclohexane

Conditions

Conditions	Yield
at 90℃; for 2h;	95%
With nickel dichloride at 20℃; for 0.5h; Neat (no solvent);	92%
With N-Bromosuccinimide In dichloromethane at 20℃; for 12h;	84%

: 110-87-2
3,4-dihydro-2H-pyran

: 556-48-9
1,4-Cyclohexanediol

A: 736-42-5
1,4-Bis--cyclohexan

B: 64230-40-6
4-(2-Tetrahydropyranyloxy)-1-cyclohexanol

Conditions

Conditions	Yield
With Dowex 50W x 2 (50-100 mesh) In toluene at 30℃; for 1.5h;	A 3% B 95%
With iodine In tetrahydrofuran at 67℃; for 0.0472222h; Irradiation;	A 15% B 77%
aluminum(III) sulfate; silica gel In hexane for 8h; Ambient temperature;	A 9 % Chromat. B 71 % Chromat.

...Expand

: 556-48-9
1,4-Cyclohexanediol

: 79-03-8
propionyl chloride

: 1,4-bis(propanoyloxy)cyclohexane

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 10 - 20℃; for 6h;	94.7%

: 556-48-9
1,4-Cyclohexanediol

ethyl carbonate derivative: ethyl carbonate derivative

: 1,4-bis(ethoxycarbonyloxy)cyclohexane

Conditions

Conditions	Yield
With γ-Fe2O3-immobilized 1,5,7-triazabicyclo[4.4.0]dec-5-ene nanoparticles (MNPs-TBD) at 125℃; for 10h;	94%

: 110-87-2
3,4-dihydro-2H-pyran

: 556-48-9
1,4-Cyclohexanediol

: 64230-40-6
4-(2-Tetrahydropyranyloxy)-1-cyclohexanol

Conditions

Conditions	Yield
With pyridinium p-toluenesulfonate In tetrahydrofuran for 6h; Ambient temperature;	93%
With lithium trifluoromethanesulfonate In 1,2-dichloro-ethane for 5.5h; Heating;	93%
With pyridinium p-toluenesulfonate In dichloromethane at 10 - 20℃; for 7h; Inert atmosphere;	84%

: 556-48-9
1,4-Cyclohexanediol

A: 13482-22-9
4-hydroxycyclohexanone

B: 637-88-7
1,4-Cyclohexanedione

Conditions

Conditions	Yield
With sodium bromate; sodium hydrogensulfite In water; acetonitrile at 20℃; for 6h; Oxidation;	A 1% B 93%
With sodium bromate; sodium hydrogensulfite In water; acetonitrile at 20℃; for 2h; Oxidation;	A 78% B 10%
With 2O34W9Zn(12-)W(6+)3Zn(2+)*2H2O; dihydrogen peroxide In water; acetonitrile at 135℃; under 2250.23 Torr; for 0.25h; Microwave irradiation;	A n/a B 58%

: 64-18-6
formic acid

: 556-48-9
1,4-Cyclohexanediol

: 137174-95-9
1,4-cyclohexanediyl diformate

Conditions

Conditions	Yield
With p-toluenesulfonyl chloride at 20℃; for 0.633333h; neat (no solvent);	93%
With Iron(III) nitrate nonahydrate; sodium iodide at 20℃; for 0.833333h; neat (no solvent);	92%

: 556-48-9
1,4-Cyclohexanediol

: 13482-22-9
4-hydroxycyclohexanone

Conditions

Conditions	Yield
With sodium bromate; ammonium cerium(IV) nitrate In water; acetonitrile	92%
With sodium bromate; ammonium cerium (IV) nitrate In water; acetonitrile for 2.5h; Reflux;	91%
With calcium hypochlorite; potassium bromide In water; acetic acid at 0℃; for 3h;	88%

: 556-48-9
1,4-Cyclohexanediol

: 1165952-92-0
cyclohexa-1,4-diene

Conditions

Conditions	Yield
With 1,1,1-trichloro-3,3,3-trifluoro-propan-2-one; toluene-4-sulfonic acid In benzene for 6h; Heating;	92%

: 5453-80-5, 19926-90-0
5-Norbornene-2-carboxaldehyde

: 556-48-9
1,4-Cyclohexanediol

: 5-norbornene-2-(4-hydroxy)cyclohexyloxy methanol

Conditions

Conditions	Yield
sodium hydride at 20℃; for 10h;	92%

: 556-48-9
1,4-Cyclohexanediol

: 59274-95-2
7-oxa-bicyclo[2.2.1]hept-5-ene-2-carbaldehyde

: oxabicyclo[2.2.1]-hept-5-ene-2-(4-hydroxy)cyclohexyloxy methanol

Conditions

Conditions	Yield
sodium hydride at 20℃; for 10h;	92%

: 556-48-9
1,4-Cyclohexanediol

: C10H19O5P

: C16H29O6P

Conditions

Conditions	Yield
at 160℃; for 5h; Molecular sieve; Inert atmosphere;	88.4%

: 556-48-9
1,4-Cyclohexanediol

: 108-24-7
acetic anhydride

: 58512-50-8
(4-hydroxycyclohexyl) acetate

Conditions

Conditions	Yield
With p-toluenesulfonyl chloride at 20℃; for 0.383333h; neat (no solvent);	88%
With triethylamine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;

: 109-80-8
1.3-propanedithiol

: 556-48-9
1,4-Cyclohexanediol

: 128345-17-5
1,5-dithiaspiro<5.5>undecan-9-ol

Conditions

Conditions	Yield
Stage #1: 1,4-Cyclohexanediol With sodium bromate; ammonium cerium (IV) nitrate In water; acetonitrile for 1h; Reflux; Stage #2: 1.3-propanedithiol With boron trifluoride diethyl etherate In dichloromethane at 0℃; for 0.25h;	88%

: 556-48-9
1,4-Cyclohexanediol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 126931-29-1
4-((tert-butyldimethylsilyl)oxy)cyclohexan-1-ol

Conditions

Conditions	Yield
With 1H-imidazole In tetrahydrofuran at 20℃; for 16h;	86.7%
With 1H-imidazole In tetrahydrofuran; N,N-dimethyl-formamide at 0℃;	66%
With 1H-imidazole In tetrahydrofuran; N,N-dimethyl-formamide at 0℃;	62%

: 556-48-9
1,4-Cyclohexanediol

: C6H13O5P

: C12H23O6P

Conditions

Conditions	Yield
at 150℃; for 4h; Molecular sieve; Inert atmosphere;	86.6%

: 556-48-9
1,4-Cyclohexanediol

: C8H17O5P

: C14H27O6P

Conditions

Conditions	Yield
With aluminum (III) chloride In toluene at 150℃; for 4h; Inert atmosphere;	84.1%

: 556-48-9
1,4-Cyclohexanediol

: 3282-30-2
pivaloyl chloride

: (+/-)-2,2-dimethylpropionic acid 4-hydroxycyclohexyl ester

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 40℃; for 18h; Inert atmosphere;	84%

: 93-40-3
(3,4-Dimethoxyphenyl)acetic acid

: 556-48-9
1,4-Cyclohexanediol

: cyclohexane 1,4-diyl bis(2-(3,4-dimethoxyphenyl)acetate)

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 24h;	84%

1,4-Cyclohexanediol Specification

The 1,4-Cyclohexanediol, with the CAS registry number 556-48-9 and EINECS registry number 209-126-2, has the systematic name of cyclohexane-1,4-diol. And the molecular formula of this chemical is C₆H₁₂O₂. It is a kind of white to off-white crystalline powder, and belongs to the product categories of Aromatic alcohols and diols. What's more, while dealing with this chemical, you should avoid contacting with skin and eyes.

The physical properties of 1,4-Cyclohexanediol are as following: (1)ACD/LogP: -0.09; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.09; (4)ACD/LogD (pH 7.4): -0.09; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 21.34; (8)ACD/KOC (pH 7.4): 21.34; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 18.46 Å²; (13)Index of Refraction: 1.526; (14)Molar Refractivity: 30.85 cm³; (15)Molar Volume: 100.4 cm³; (16)Polarizability: 12.23×10^-24cm³; (17)Surface Tension: 40.7 dyne/cm; (18)Density: 1.156 g/cm³; (19)Flash Point: 65.6 °C; (20)Enthalpy of Vaporization: 56.9 kJ/mol; (21)Boiling Point: 252.4 °C at 760 mmHg; (22)Vapour Pressure: 0.00301 mmHg at 25°C.

Uses of 1,4-Cyclohexanediol: It can react with 3,4-dihydro-2H-pyran to produce 4-(2-Tetrahydropyranyloxy)-1-cyclohexanol. This reaction will need reagent PPTS, and the solvent tetrahydrofuran. The reaction time is 6 hours with ambient temperature, and the yield is about 93%.

1,4-Cyclohexanediol can react with 3,4-dihydro-2H-pyran to produce 4-(2-Tetrahydropyranyloxy)-1-cyclohexanol

You can still convert the following datas into molecular structure:
(1)SMILES: OC1CCC(O)CC1
(2)InChI: InChI=1/C6H12O2/c7-5-1-2-6(8)4-3-5/h5-8H,1-4H2
(3)InChIKey: VKONPUDBRVKQLM-UHFFFAOYAF

Product Name

1,4-Cyclohexanediol

Synthetic route

1,4-Cyclohexanediol Specification

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