• Name

  2-(2-Methoxyphenoxy)ethylamine hydrochloride

• EINECS 1312995-182-4
• CAS No. 64464-07-9
• Density
• Solubility
• Melting Point 107-109 °C
• Formula C₉H₁₃NO₂.HCl
• Boiling Point 261.1 °C at 760 mmHg
• Molecular Weight 203.669
• Flash Point 120.7 °C
• Transport Information
• Appearance white solid
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Ethanamine,2-(2-methoxyphenoxy)-, hydrochloride (9CI);Ethylamine, 2-(o-methoxyphenoxy)-,hydrochloride (7CI);
• PSA 44.48000
• LogP 2.53500

Synthetic route

carbonic acid 2-chloro-1-chloro-methyl-ethyl ester phenyl ester

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

374779-56-3

1,3-dichloro-2-propyl-2-(2-methoxyphenoxy)ethylcarbamate(II)

Conditions

Conditions	Yield
Stage #1: 2-[(2-methoxy)phenoxy]ethylamine hydrochloride With triethylamine In ethanol for 0.0833333h; Stage #2: carbonic acid 2-chloro-1-chloro-methyl-ethyl ester phenyl ester In ethanol at 20℃;	97%

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

1836-62-0

2-(2-methoxy-phenoxy)-ethylamine

Conditions

Conditions	Yield
With sodium hydroxide In water at 0℃; pH=12 - 14;	97%

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

51997-51-4

4-(2,3-epoxypropoxy)carbazole

72956-09-3

carvedilol

Conditions

Conditions	Yield
Stage #1: 2-[(2-methoxy)phenoxy]ethylamine hydrochloride With sodium hydroxide In water at 20℃; pH=9 - 9.5; Stage #2: 4-(2,3-epoxypropoxy)carbazole In water at 80 - 85℃; for 0.75 - 1h; Product distribution / selectivity;	45.99%
Stage #1: 2-[(2-methoxy)phenoxy]ethylamine hydrochloride With sodium hydroxide In water; isopropyl alcohol at 20℃; pH=9 - 9.5; Stage #2: 4-(2,3-epoxypropoxy)carbazole In water; isopropyl alcohol for 4 - 5h; Product distribution / selectivity; Heating / reflux;	43.05%
With potassium carbonate In i-Amyl alcohol at 80 - 85℃; for 7h;	41%
With calcium carbonate In isopropyl alcohol at 80℃; for 4h;

50-00-0

formaldehyd

15324-42-2

2,2-diphenylcyclopentanone

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

1353573-77-9

5-({[2-(2-methoxyphenoxy)ethyl]amino}methyl)-2,2-diphenylcyclopentan-1-one

Conditions

Conditions	Yield
In ethanol Reflux;	36%

...Expand

50-00-0

formaldehyd

83-33-0

inden-1-one

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

2-{[2-(2-Methoxy-phenoxy)-ethylamino]-methyl}-indan-1-one

Conditions

Conditions	Yield
In isopropyl alcohol Heating;

...Expand

50-00-0

formaldehyd

529-34-0

3,4-dihydronaphthalene-1(2H)-one

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

40077-29-0

2-{[2-(2-Methoxy-phenoxy)-ethylamino]-methyl}-3,4-dihydro-2H-naphthalen-1-one

Conditions

Conditions	Yield
In isopropyl alcohol Heating;

...Expand

122-60-1

Phenyl glycidyl ether

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

3258-69-3

N-<2-(2-Methoxy-phenoxy)-aethyl>-2-hydroxy-3-phenoxy-propylamin

Conditions

Conditions	Yield
With sodium hydroxide In propan-1-ol Heating;

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

2210-74-4

2-(2-methoxy-phenoxymethyl)-oxirane

3258-68-2

1-(2-methoxyphenoxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

Conditions

Conditions	Yield
With sodium hydroxide In propan-1-ol Heating;

914086-10-5

2-chloro-6-(5-methyl-1H-pyrazol-3-ylamino)-4-methylnicotinonitrile

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

2-(2-(2-methoxyphenoxy)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)-4-methylnicotinonitrile

Conditions

Conditions	Yield
With sodium hydrogencarbonate In dimethyl sulfoxide at 100℃; for 27h;

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

180987-80-8

5-(((9H-carbazol-4-yl)oxy)methyl)-3-(2-(2-methoxyphenoxy)ethyl)oxazolidin-2-one

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: triethylamine / ethanol / 0.08 h 1.2: 20 °C 2.1: sodium hydride / tetrahydrofuran / 1 h / 20 - 67 °C / Nitrogen atmosphere 3.1: potassium carbonate / sodium dithionite; potassium iodide / ethanol / 24 h / Nitrogen atmosphere; Heating / reflux View Scheme

64464-07-9

2-[(2-methoxy)phenoxy]ethylamine hydrochloride

72956-09-3

carvedilol

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: triethylamine / ethanol / 0.08 h 1.2: 20 °C 2.1: sodium hydride / tetrahydrofuran / 1 h / 20 - 67 °C / Nitrogen atmosphere 3.1: potassium carbonate / sodium dithionite; potassium iodide / ethanol / 24 h / Nitrogen atmosphere; Heating / reflux 4.1: sodium hydroxide / ethanol; water / 20 °C / Nitrogen atmosphere View Scheme

2-(2-Methoxyphenoxy)ethylamine hydrochloride Chemical Properties

2-(2-Methoxyphenoxy)ethylamine hydrochloride Uses

2-(2-Methoxyphenoxy)ethylamine hydrochloride Safety Profile

2-(2-Methoxyphenoxy)ethylamine hydrochloride Specification