Product Name

  • Name

    2-Hydroxy-5-trifluoromethylpyridine

  • EINECS 627-625-7
  • CAS No. 33252-63-0
  • Article Data14
  • CAS DataBase
  • Density 1.423 g/cm3
  • Solubility
  • Melting Point 145-149 °C(lit.)
  • Formula C6H4F3NO
  • Boiling Point 286.815 °C at 760 mmHg
  • Molecular Weight 163.099
  • Flash Point 127.262 °C
  • Transport Information
  • Appearance Yellow to brown powder
  • Safety 26-36
  • Risk Codes 36/37/38-65-20/21/22-20/21
  • Molecular Structure Molecular Structure of 33252-63-0 (2-Hydroxy-5-trifluoromethylpyridine)
  • Hazard Symbols HarmfulXn,IrritantXi
  • Synonyms 2(1H)-Pyridone,5-(trifluoromethyl)- (8CI);2-Hydroxy-5-(trifluoromethyl)pyridine;5-(Trifluoromethyl)-2-pyridinol;5-(Trifluoromethyl)pyridin-2(1H)-one;5-Trifluoromethyl-2-hydroxypyridine;2(1H)-Pyridinone,5-(trifluoromethyl)-;
  • PSA 33.12000
  • LogP 1.80600

2-Hydroxy-5-trifluoromethylpyridine Chemical Properties


IUPAC Name: 5-(Trifluoromethyl)-1H-pyridin-2-one 
Empirical Formula: C6H4F3NO
Molecular Weight: 163.0973
Canonical SMILES: C1=CC(=O)NC=C1C(F)(F)F
InChI: InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)
InChIKey: BYRJSCNPUHYZQE-UHFFFAOYSA-N
Melting Point: 145-149 °C(lit.)
Index of Refraction: 1.457
Molar Refractivity: 31.206 cm3
Molar Volume: 114.598 cm3
Surface Tension: 32.511 dyne/cm
Density: 1.423 g/cm3
Flash Point: 127.262 °C
Enthalpy of Vaporization: 54.705 kJ/mol
Boiling Point: 286.815 °C at 760 mmHg
Vapour Pressure: 0.001 mmHg at 25 °C
Product Categories of 2-Hydroxy-5-trifluoromethylpyridine (CAS NO.33252-63-0): blocks; Pyridines; Heterocyclic Series; Pyridine; Nucleotides and Nucleosides; Bases & Related Reagents; Nucleotides

2-Hydroxy-5-trifluoromethylpyridine Uses

 2-Hydroxy-5-trifluoromethylpyridine as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

2-Hydroxy-5-trifluoromethylpyridine Safety Profile

Hazard Codes : IrritantXi,HarmfulXn
Risk Statements : 36/37/38-65-20/21/22-20/21
R36/37/38:Irritating to eyes, respiratory system and skin. 
R65:Harmful: may cause lung damage if swallowed. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R20/21:Harmful by inhalation and in contact with skin.
Safety Statements : 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany : 3
Hazard Note of 2-Hydroxy-5-trifluoromethylpyridine (CAS NO.33252-63-0): Irritant

2-Hydroxy-5-trifluoromethylpyridine Specification

 2-Hydroxy-5-trifluoromethylpyridine (CAS NO.33252-63-0), its Synonyms are 2H-5TFMP ; 5-(Trifluoromethyl)-2(1H)-pyridinone ; 2(1H)-Pyridinone, 5-(trifluoromethyl)-  . It is yellow to brown powder.

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