2-Propanone, 1-mercapto- supplier

Name
2-Propanone, 1-mercapto-
EINECS
CAS No. 24653-75-6
Article Data21
CAS DataBase
Density 1.01 g/cm³
Solubility soluble in oil and alcohol
Melting Point 45 °C
Formula C₃H₆OS
Boiling Point 133.6 ºC at 760 mmHg
Molecular Weight 90.146
Flash Point 34.6 ºC
Transport Information
Appearance colourless to pale yellow liquid
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 2-Propanone,mercapto- (6CI,7CI);1-Mercapto-2-propanone;3-Mercapto-2-propanone;Mercaptoacetone;2-Propanone,1-mercapto- (8CI,9CI);
PSA 55.87000
LogP 0.50520

Synthetic route

: 78-95-5
chloroacetone

: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
With sodium hydrogen sulfide In ethanol; water at 10 - 20℃; for 1h;	99%
With sodium hydroxide; hydrogen sulfide for 1h;	71%
With sodium hydrogensulfide In water at 0℃; for 1h;	70%

: 78-95-5
chloroacetone

A: 63578-76-7
4-thiaheptane-2,6-dione

B: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
With sodium hydrogensulfide; water at 0℃;
With sodium hydrogensulfide; water at 0℃;

: 22131-92-6
thietane-3-one

: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
With sodium hydrogensulfide

: 49762-80-3
O-ethyl S-2-oxopropyl carbonodithioate

: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
With sodium hydroxide In dichloromethane at 20℃; for 0.25h;	80 mg

: 598-31-2
1-bromoacetone

: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
With hydrogen sulfide; sodium methylate In methanol

: 7732-18-5
water

: 78-95-5
chloroacetone

NaHS: NaHS

A: 63578-76-7
4-thiaheptane-2,6-dione

B: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
at 0℃;

...Expand

2,5c-dimethyl-<1,4>dithiane-2r,5t-diol: 2,5c-dimethyl-<1,4>dithiane-2r,5t-diol

: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield

: 14660-20-9
thioacetylacetone

: 24653-75-6
1-mercaptopropan-2-one

Conditions

Conditions	Yield
With sodium hydroxide In methanol at 20℃; for 3h; Inert atmosphere;

: 1616360-22-5
4-(4-bromo-2-methylbenzylidene)-1-methyl-3-(pyrimidin-4-yl)-1H-pyrazol-5(4H)-imine

: 24653-75-6
1-mercaptopropan-2-one

: 1616360-21-4
C19H18BrN5S

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In acetonitrile at 90℃; for 16h;	100%

: 14304-75-7
1-chloronaphthalene-2-carbaldehyde

: 24653-75-6
1-mercaptopropan-2-one

: 51925-23-6
acetylnaphtho[1,2-b]thiophene

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	99%

: 16588-02-6
4-chloro-3-cyanonitrobenzene

: 24653-75-6
1-mercaptopropan-2-one

: 74617-23-5
2-acetyl-3-amino-5-nitrobenzothiophen

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	99%

: 6602-54-6
2-chloro-3-pyridinecarbonitrile

: 24653-75-6
1-mercaptopropan-2-one

: 52505-41-6
2-acetyl-3-aminopyrido[2,3-b]thiophene

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	96%

: 40086-66-6
2-Bromoacetylpyridine

: 24653-75-6
1-mercaptopropan-2-one

: 1440682-72-3
1-(2-oxo-2-(pyridin-2-yl)ethylthio)propan-2-one

Conditions

Conditions	Yield
With sodium hydrogencarbonate In acetonitrile at 0℃; Inert atmosphere; Schlenk technique;	96%

: 24653-75-6
1-mercaptopropan-2-one

: 2632-88-4
ethyl N,N'-tetraethyldiamidophosphite

: 126199-82-4
O-ethyl S-(2-oxopropyl) diethylphosphoramidothioite

Conditions

Conditions	Yield
	95%

: 574-98-1
2-(2-bromoethyl)isoindoline-1,3-dione

: 24653-75-6
1-mercaptopropan-2-one

: 98586-88-0
5-oxo-1-phthalimido-3-thiahexane

Conditions

Conditions	Yield
With sodium ethanolate In ethanol for 1h; Heating;	92%

: 79917-06-9
6-chloro-3,5-dicyano-2-<<(dimethylamino)methylene>amino>pyrazine

: 24653-75-6
1-mercaptopropan-2-one

: 79917-08-1
1-<<3,5-dicyano-2-<<(dimethylamino)methylene>amino>-6-pyrazinyl>thio>-2-propanone

Conditions

Conditions	Yield
With triethylamine In ethanol for 0.5h;	92%

: 53189-26-7
palladium(II) acetate trimer

: 24653-75-6
1-mercaptopropan-2-one

: [Pd(μ-SCH2C(O)Me)2]6

Conditions

Conditions	Yield
In ethanol byproducts: HOAc; Ar-atmosphere; molar ratio Pd:sulfide=1:2; slow addn. of sulfide to Pd-salt (0°C, 1 h); filtration, washing (EtOH), drying (vac.); elem. anal.;	92%

: 873-32-5
2-Chlorobenzonitrile

: 24653-75-6
1-mercaptopropan-2-one

: 34263-61-1
2-acetyl-3-aminobenzothiophen

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	91%

: 6-bromo-1-chloro-3,4-dihydronaphthalene-2-carbaldehyde

: 24653-75-6
1-mercaptopropan-2-one

: 1-(7-bromo-4,5-dihydronaphtho[1,2-b]thiophen-2-yl)ethan-1-one

Conditions

Conditions	Yield
Stage #1: 1-mercaptopropan-2-one With sodium methylate In methanol at 0℃; for 0.25h; Inert atmosphere; Stage #2: 6-bromo-1-chloro-3,4-dihydronaphthalene-2-carbaldehyde In methanol at 0 - 20℃; for 3h; Inert atmosphere;	91%

: 15013-71-5
2-chloro-3-methylbenzonitrile

: 24653-75-6
1-mercaptopropan-2-one

: 1426444-98-5
2-acetyl-3-amino-7-methylbenzo[b]thiophene

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	90%

: 16205-84-8
ethyl 3-(trimethylsilyl)propynoate

: 24653-75-6
1-mercaptopropan-2-one

: ethyl 4-methyl-2-(trimethylsilyl)thiophene-3-carboxylate

Conditions

Conditions	Yield
Stage #1: ethyl 3-(trimethylsilyl)propynoate; 1-mercaptopropan-2-one With potassium tert-butylate In toluene at 20℃; for 3h; Inert atmosphere; Green chemistry; Stage #2: With acetic anhydride In toluene at 80℃; for 3h; Inert atmosphere; Green chemistry; regioselective reaction;	90%

: 2-bromo-2-chloro-3-[3-(trifluoromethyl)phenyl]propanenitrile

: 24653-75-6
1-mercaptopropan-2-one

: 1-{3-amino-5-[3-(trifluoromethyl)phenyl]thiophen-2-yl}-ethanone

Conditions

Conditions	Yield
With sodium methylate In methanol at 20℃; for 1h;	90%

: 3-(3-acetylphenyl)-2-bromo-2-chloropropanenitrile

: 24653-75-6
1-mercaptopropan-2-one

: 1-[3-(5-acetyl-4-aminothiophen-2-yl)phenyl]ethanone

Conditions

Conditions	Yield
With sodium methylate In methanol at 20℃; for 1h;	90%

: 71585-26-7
6-morpholinonaphthalen-2-ol

: 24653-75-6
1-mercaptopropan-2-one

: C17H19NO3S

Conditions

Conditions	Yield
With cobalt phthalocyanine-tetrasodiumsulfonate; oxygen In water at 100℃; for 15h; Schlenk technique;	89%

: 54949-01-8
5-chloro-8,9-dihydro-7H-benzocycloheptene-6-carbaldehyde

: 24653-75-6
1-mercaptopropan-2-one

: 1-(5,6-dihydro-4H-benzo[6,7]cyclohepta[1,2-b]thiophen-2-yl)ethanone

Conditions

Conditions	Yield
Stage #1: 1-mercaptopropan-2-one With sodium methylate In methanol at 0℃; for 0.25h; Inert atmosphere; Stage #2: 9-chloro-6,7-dihydro-5H-benzocycloheptene-8-carbaldehyde In methanol at 0 - 20℃; for 3h; Inert atmosphere;	89%

: 83-38-5
2,6-dichlorobenzaldehyde

: 24653-75-6
1-mercaptopropan-2-one

: 66490-34-4
1-(4-chloro-1H-benzo[b]thiophen-2-yl)ethanone

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	88%

: 3262-03-1
1-chloro-2-formyl-3,4-dihydronaphthalene

: 24653-75-6
1-mercaptopropan-2-one

: 62615-59-2
1-(4,5-dihydronaphtho[1,2-b]thiophen-2-yl)ethanone

Conditions

Conditions	Yield
Stage #1: 1-mercaptopropan-2-one With sodium methylate In methanol at 0℃; for 0.25h; Inert atmosphere; Stage #2: 1-chloro-2-formyl-3,4-dihydronaphthalene In methanol at 0 - 20℃; for 3h; Inert atmosphere;	88%

: 24477-82-5
Triethyl-[(Z)-3-(4-methoxy-phenyl)-3-oxo-propenyl]-ammonium; chloride

: 24653-75-6
1-mercaptopropan-2-one

: 132039-37-3
(Z)-1-(4-Methoxy-phenyl)-3-(2-oxo-propylsulfanyl)-propenone

Conditions

Conditions	Yield
In ethanol at 78℃; for 1h;	87%

: 6361-21-3
2-chloro-5-nitrobenzaldehyde

: 24653-75-6
1-mercaptopropan-2-one

: 114305-93-0
1-(5-nitrobenzo[b]thiophen-2-yl)ethanone

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	86%
With potassium carbonate In water at 90℃;	86%

: 36404-88-3
2-chloro-3-carbaldehydepyridine

: 24653-75-6
1-mercaptopropan-2-one

: 18354-56-8
1-(thiopheno[2,3-b]pyridin-2-yl)ethanone

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	86%

: 2-bromo-2-chloro-3-(4-methylphenyl)propanenitrile

: 24653-75-6
1-mercaptopropan-2-one

: 1-[3-amino-5-(4-methylphenyl)thiophen-2-yl]ethanone

Conditions

Conditions	Yield
With sodium methylate In methanol at 20℃; for 1h;	85%

: 89-98-5
2-chloro-benzaldehyde

: 24653-75-6
1-mercaptopropan-2-one

: 22720-75-8
2-acetyl benzo[b]thiophene

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	84%

: 1194-65-6
2,6-dichloro-benzonitrile

: 24653-75-6
1-mercaptopropan-2-one

: 52673-88-8
1-(3-amino-4-chloro-benzothiophen-2-yl)-ethanone

Conditions

Conditions	Yield
With potassium carbonate In water at 90℃; for 2h; Green chemistry;	82%

: 75-36-5
acetyl chloride

: 24653-75-6
1-mercaptopropan-2-one

: 57360-11-9
1-acetylthio-2-propanone

Conditions

Conditions	Yield
With triethylamine In acetonitrile at 10℃; for 2h;	81%

: 24653-75-6
1-mercaptopropan-2-one

: 66928-24-3
2,5-dimethyl-2,5-endo-oxy-1,4-dithiane

Conditions

Conditions	Yield
With diethylphosphoramidous dichloride In benzene Heating;	81%
With butyl dichlorophosphite In benzene Heating;	64%

: 2-bromo-2-chloro-3-(4-fluorophenyl)propanenitrile

: 24653-75-6
1-mercaptopropan-2-one

: 1-[3-amino-5-(4-fluorophenyl)thiophen-2-yl]ethanone

Conditions

Conditions	Yield
With sodium methylate In methanol at 20℃; for 1h;	81%

: 38480-36-3
Triethyl-((Z)-4-methyl-3-oxo-pent-1-enyl)-ammonium; chloride

: 24653-75-6
1-mercaptopropan-2-one

: 132039-40-8
(Z)-4-Methyl-1-(2-oxo-propylsulfanyl)-pent-1-en-3-one

Conditions

Conditions	Yield
In ethanol at 78℃; for 1h;	80%

2-Propanone, 1-mercapto- Chemical Properties

IUPAC Name: 1-Sulfanylpropan-2-one
Canonical SMILES: CC(=O)CS
InChI: InChI=1S/C3H6OS/c1-3(4)2-5/h5H,2H2,1H3
InChIKey: USVCRBGYQRVTNK-UHFFFAOYSA-N
Molecular Weight: 90.14414 [g/mol]
Molecular Formula: C₃H₆OS
XLogP3-AA: 0.3
H-Bond Donor: 0
H-Bond Acceptor: 1
Index of Refraction: 1.447
Molar Refractivity: 23.87 cm³
Molar Volume: 89.2 cm³
Surface Tension: 29.7 dyne/cm
Density: 1.01 g/cm³
Flash Point: 34.6 °C
Enthalpy of Vaporization: 37.11 kJ/mol
Boiling Point: 133.6 °C at 760 mmHg
Vapour Pressure: 8.39 mmHg at 25 °C
Appearance: colourless to pale yellow liquid
Product Categories of 2-Propanone, 1-mercapto- (CAS NO.24653-75-6): thiol Flavor

2-Propanone, 1-mercapto- Specification

2-Propanone, 1-mercapto- (CAS NO.24653-75-6), its Synonyms are 1-Mercapto-2-propanone ; 2-Propanone,mercapto- (6CI,7CI) ; 1-Mercapto-2-propanone ; 3-Mercapto-2-propanone ; Mercaptoacetone ; 2-Propanone,1-mercapto- (8CI,9CI) .

Product Name

2-Propanone, 1-mercapto-

Synthetic route

2-Propanone, 1-mercapto- Chemical Properties

2-Propanone, 1-mercapto- Specification

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