• Name

  3,5-Dibromoanisole

• EINECS
• CAS No. 74137-36-3
• Article Data43
• CAS DataBase
• Density 1.823 g/cm³
• Solubility
• Melting Point 38-45 °C
• Formula C₇H₆Br₂O
• Boiling Point 249.7 °C at 760 mmHg
• Molecular Weight 265.932
• Flash Point 98.1 °C
• Transport Information UN 2811 6.1/PG 3
• Appearance solid
• Safety 45
• Risk Codes 25
• Molecular Structure
• Hazard Symbols T
• Synonyms 1,3-Dibromo-5-methoxybenzene;3,5-Bromo-1-methoxyphenyl;
• PSA 9.23000
• LogP 3.22020

Synthetic route

626-41-5

3,5-dibromophenol

74-88-4

methyl iodide

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With potassium carbonate In acetone at 60℃; for 16h;	100%
With potassium carbonate; potassium iodide In acetonitrile at 95℃; for 3h; Inert atmosphere;	98.1%
With potassium carbonate In acetone at 20℃; for 15h; Heating; Reflux;	97%

626-39-1

1,3,5-trisbromobenzene

124-41-4

sodium methylate

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 90℃; for 12h;	98%
In N,N-dimethyl-formamide at 80℃; for 8h;	70%
In N,N-dimethyl-formamide at 80℃; for 28h; Inert atmosphere;	48.9%
In pyridine; methanol at 115℃; Rate constant; Product distribution;
In N,N-dimethyl-formamide at 90℃; for 0.25h;

95970-05-1

2,6-dibromo-4-methoxyaniline

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With sulfuric acid; hypophosphorous acid; sodium nitrite In toluene at 0℃; for 4.5h;	96%

1435-51-4

1,3-dibromo-5-fluorobenzene

124-41-4

sodium methylate

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃;	95%
In methanol; DMF (N,N-dimethyl-formamide) at 0 - 20℃; for 1h;
In N,N-dimethyl-formamide at 20℃;

67-56-1

methanol

6311-60-0

3,5-dibromonitrobenzene

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With potassium hydroxide; tetrabutylammomium bromide In tetramethylurea at 20℃; for 24h;	84%
With tetrabutylammomium bromide; oxygen; potassium hydroxide In tetramethylurea at 20℃;	84%
With potassium hydroxide; tetrabutylammomium bromide; tetramethylurea at 20℃; for 24.25h;	84%
With potassium hydroxide; tetrabutylammomium bromide In tetramethylurea at 20℃; for 24.25h;	84%

626-39-1

1,3,5-trisbromobenzene

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With sodium methylate In N,N-dimethyl-formamide at 100℃; for 12h;	83%

626-39-1

1,3,5-trisbromobenzene

124-41-4

sodium methylate

A

626-41-5

3,5-dibromophenol

B

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
at 130℃;
at 120 - 130℃; im geschlossenen Rohr;

...Expand

626-39-1

1,3,5-trisbromobenzene

A

626-41-5

3,5-dibromophenol

B

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With methanol; sodium at 120 - 130℃; im geschlossenen Rohr;

88149-47-7

2,4-dibromo-6-methoxyaniline

A

16618-67-0

3-bromo-5-nitroanisole

B

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With potassium disulphite; nitric acid nachfolgend Verkochen mit Alkohol in Gegenwart von Kupfersulfat;
With potassium disulphite; nitric acid Diazotization.folgend Verkochen mit Alkohol in Gegenwart von Kupfersulfat;

88149-47-7

2,4-dibromo-6-methoxyaniline

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With ethanol Diazotization;
With ethanol; sulfuric acid; sodium nitrite 1.) 0 deg C, 2.) 0 deg C, 15 min, 3.) heating to 80 deg C, 1 h;; Yield given. Multistep reaction;
beim Diazotieren und Kochen des Diazoniumsalzes in Alkohol;

626-41-5

3,5-dibromophenol

77-78-1

dimethyl sulfate

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With sodium hydroxide
With potassium hydroxide
With aq. alkali

608-71-9

Pentabromophenol

74-88-4

methyl iodide

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With aluminium trichloride; potassium carbonate 1.) benzene; Multistep reaction;

88149-47-7

2,4-dibromo-6-methoxyaniline

7697-37-2

nitric acid

potassium pyrosulfite

potassium pyrosulfite

A

16618-67-0

3-bromo-5-nitroanisole

B

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
beim nachfolgenden Verkochen mit Alkohol in Gegenwart von Kupfersulfat.Diazotization;

...Expand

626-39-1

1,3,5-trisbromobenzene

124-41-4

sodium methylate

A

621-23-8

1,2,3-trimethoxybenzene

B

20469-65-2

1-bromo-3,5-dimethoxybenzene

C

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With copper(I) chloride; air In N,N-dimethyl-formamide at 110℃;

...Expand

90-04-0

2-methoxy-phenylamine

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: glacial acetic acid / beim Bromieren 2: beim Diazotieren und Kochen des Diazoniumsalzes in Alkohol View Scheme

626-40-4

3,5-dibromoaniline

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: Diazotization.Verkochen der Diazoniumsulfatloesung mit Schwefelsaeure 2: NaOH-solution View Scheme

acetic acid-(2,4-dibromo-6-methoxy-anilide)

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: concentrated hydrochloric acid 2: potassium pyrosulfite; nitric acid / Diazotization.folgend Verkochen mit Alkohol in Gegenwart von Kupfersulfat View Scheme

1435-51-4

1,3-dibromo-5-fluorobenzene

74137-36-3

3,5-dibromoanisole

Conditions

Conditions	Yield
With sodium methylate In methanol; DMF (N,N-dimethyl-formamide) at 0 - 20℃; for 1h;
With sodium methylate In methanol; N,N-dimethyl-formamide

3,5-Dibromoanisole Chemical Properties

The molecular formula of 3,5-Dibromoanisole(74137-36-3) is C₇H₆Br₂O and its formula weight is 265.93.
The density of 3,5-Dibromoanisole(74137-36-3) is 1.823 and it has a melting point of  38-45°C. The boiling point is  249.7°C.  Its flash point is  98.1°C.
The chemical synonyms of 3,5-Dibromoanisole(74137-36-3) are 1,3-dibromo-5-methoxybenzene;3,5-DIBROMOANISOLE
The molecular structure of 3,5-Dibromoanisole(74137-36-3):

3,5-Dibromoanisole Safety Profile