3-Benzyloxyphenol supplier | CasNO.3769-41-3

Name
3-Benzyloxyphenol
EINECS
CAS No. 3769-41-3
Article Data48
CAS DataBase
Density 1.16 g/cm³
Solubility
Melting Point 50 °C
Formula C₁₃H₁₂O₂
Boiling Point 358 °C at 760 mmHg
Molecular Weight 200.237
Flash Point 212.117 °C
Transport Information
Appearance
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Phenol,m-(benzyloxy)- (6CI,7CI,8CI);Resorcinol monobenzyl ether;m-(Benzyloxy)phenol;
PSA 29.46000
LogP 2.97120

Synthetic route

: 96057-78-2
1-benzoyloxy-3-benzyloxy-benzene

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With sodium hydroxide In methanol	99%

: C15H14O2

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With acetic acid; trifluoroacetic acid In water for 0.0666667h; Reflux;	98%

: 81499-29-8
3-Benzyloxyphenyl acetate

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With sodium hydroxide In tetrahydrofuran	96%
With sodium hydroxide In tetrahydrofuran	96%

: C16H16O4

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol at 20℃; for 1h;	86%

: 156682-54-1
3-(benzyloxy)phenylboronic acid

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With dihydrogen peroxide In water at 30℃; Green chemistry;	85%

: 100-39-0
benzyl bromide

: 108-46-3
recorcinol

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With potassium carbonate at 80℃; for 2h;	83%
With potassium carbonate In acetone Heating;	77%
With potassium carbonate In acetonitrile for 96h; Heating;	70%

: 3769-42-4
1,3-bis(benzyloxy)benzene

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In acetic acid at 25℃; under 760 Torr;	81%

: 107623-21-2
1-(benzyloxy)-3-iodobenzene

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With basolite C300; potassium hydroxide In water; dimethyl sulfoxide at 125℃; for 12h;	80%

: 185613-44-9
3-((2-Bromobenzyl)oxy)phenol

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium tert-butylate In N,N-dimethyl-formamide at 95℃; for 48h;	77%

: 100-44-7
benzyl chloride

: 108-46-3
recorcinol

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In acetone for 48.5h; Reflux;	72%
Stage #1: benzyl chloride; recorcinol In dimethyl sulfoxide at 20℃; Stage #2: With potassium hydroxide at 90℃; for 16h;	55%
With sodium hydride In N,N-dimethyl-formamide for 18h; Ambient temperature;	54%

: (1-(2-(3-benzyloxy)phenoxy)ethyl)piperidine

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With boron tribromide dimethyl sulfide complex In dichloromethane for 0.416667h; Inert atmosphere;	70%
Multi-step reaction with 3 steps 1: peracetic acid; acetic acid / dichloromethane / 0.07 h 2: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 3: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

: 1484-26-0
3-(benzyloxy)aniline

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Stage #1: 3-(benzyloxy)aniline With sulfuric acid at 20℃; Cooling with ice; Stage #2: With sodium nitrite In water Reflux;	64%

: 4-((3-(benzyloxy)phenoxy)methyl)-1-tosyl-1H-1,2,3-triazole

A: 3769-41-3
3-Benzyloxyphenol

B: (E)-N-(7-(benzyloxy)chroman-4-ylidene)-4-methylbenzenesulfonamide

Conditions

Conditions	Yield
In toluene Reflux; Inert atmosphere;	A n/a B 63%

: 108-46-3
recorcinol

PhCH2-halide: PhCH2-halide

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Stage #1: recorcinol With pyridine; poly(ethylene glycol) 4000; oxalyl dichloride In dichloromethane at 20℃; for 18h; Stage #2: PhCH2-halide With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 18h; Stage #3: With sodium hydroxide at 20℃; for 2h;	56%

: 100-39-0
benzyl bromide

: 108-46-3
recorcinol

A: 3769-42-4
1,3-bis(benzyloxy)benzene

B: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With potassium carbonate In acetone at 60℃; for 4h;	A n/a B 32%

...Expand

: 136-36-7
benzoate d'hydroxy-3 phenyle

: 620-05-3
iodomethylbenzene

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With N,N-dimethyl-formamide; silver(l) oxide Behandeln des erhaltenen Reaktionsprodukts mit aethanol. KOH;

: 1700-37-4
3-Benzyloxybenzaldehyde

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 24h;

: 136-36-7
benzoate d'hydroxy-3 phenyle

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 76 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran 2: 99 percent / aq. NaOH / methanol View Scheme

: 100-51-6
benzyl alcohol

BocNH-C(=NBoc)-SCH2-terminated resin: BocNH-C(=NBoc)-SCH2-terminated resin

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 76 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran 2: 99 percent / aq. NaOH / methanol View Scheme

: 70371-58-3
1-(benzyloxy)-3-(prop-2-yn-1-yloxy)benzene

A: 3769-41-3
3-Benzyloxyphenol

B: (E)-N-(7-(benzyloxy)chroman-4-ylidene)-4-methylbenzenesulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: copper(I) thiophene-2-carboxylate / toluene / 2 h / 20 °C / Inert atmosphere 2: toluene / Reflux; Inert atmosphere View Scheme

: 3-(2-(piperidin-1-yl)ethoxy)phenyl acetate

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: ammonia / methanol / 0.33 h / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 5 steps 1.1: ammonia / methanol / 0.33 h / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

Yield

Multi-step reaction with 3 steps
1.1: ammonia / methanol / 0.33 h / 20 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere
View Scheme

Multi-step reaction with 5 steps
1.1: ammonia / methanol / 0.33 h / 20 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h
4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux
5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux
View Scheme

: C20H25NO3

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 2: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

: 1-(2-(3-((4-methoxybensyl)oxy)phenoxy)ethyl)piperidine

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: acetic acid / 2.5 h / Reflux 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 5 steps 1.1: acetic acid / 2.5 h / Reflux 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

: 1-(2-(3-((tert-butyldiphenylsilyl)oxy)phenoxy)ethyl)piperidine

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 5 steps 1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

Yield

Multi-step reaction with 3 steps
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere
View Scheme

Multi-step reaction with 5 steps
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h
4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux
5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux
View Scheme

: 1-(2-(3-(allyloxy)phenoxy)ethyl)piperidine

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: hydrogenchloride / water / 1 h / 75 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 5 steps 1.1: hydrogenchloride / water / 1 h / 75 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

Yield

Multi-step reaction with 3 steps
1.1: hydrogenchloride / water / 1 h / 75 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere
View Scheme

Multi-step reaction with 5 steps
1.1: hydrogenchloride / water / 1 h / 75 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h
4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux
5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux
View Scheme

: 1-(2-(3-((tetrahydro-2H-pyran-2-yl)oxy)phenoxy)ethyl)piperidine

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: acetic acid / water / 0.02 h / Reflux 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 5 steps 1.1: acetic acid / water / 0.02 h / Reflux 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

Yield

Multi-step reaction with 3 steps
1.1: acetic acid / water / 0.02 h / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere
View Scheme

Multi-step reaction with 5 steps
1.1: acetic acid / water / 0.02 h / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h
4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux
5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux
View Scheme

: 3-(2-(piperidin-1-yl)ethoxy)phenol

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 1.2: 0.33 h / 20 °C / Inert atmosphere 2.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 4 steps 1.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 1.2: 0.33 h / 20 °C / Inert atmosphere 2.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 3.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 4.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

: 1-(2-(3-(2-cyclohexylethoxy)phenoxy)ethyl)piperidine

: 3769-41-3
3-Benzyloxyphenol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: hydrogen bromide / water / 1.17 h / Reflux 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere View Scheme
Multi-step reaction with 5 steps 1.1: hydrogen bromide / water / 1.17 h / Reflux 2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere 2.2: 0.33 h / 20 °C / Inert atmosphere 3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h 4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux 5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux View Scheme

Yield

Multi-step reaction with 3 steps
1.1: hydrogen bromide / water / 1.17 h / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: boron tribromide dimethyl sulfide complex / dichloromethane / 0.42 h / Inert atmosphere
View Scheme

Multi-step reaction with 5 steps
1.1: hydrogen bromide / water / 1.17 h / Reflux
2.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 55 °C / Inert atmosphere
2.2: 0.33 h / 20 °C / Inert atmosphere
3.1: peracetic acid; acetic acid / dichloromethane / 0.07 h
4.1: N,O-bis-(trimethylsilyl)-acetamide / toluene / 0.58 h / Reflux
5.1: acetic acid; trifluoroacetic acid / water / 0.07 h / Reflux
View Scheme

: 3769-41-3
3-Benzyloxyphenol

: 3433-80-5
1-Bromo-2-bromomethyl-benzene

: 309254-31-7
1-bromo-2-(3-benzyloxyphenyloxymethyl)benzene

Conditions

Conditions	Yield
Stage #1: 3-Benzyloxyphenol With sodium hydride In tetrahydrofuran for 0.5h; Metallation; Heating; Stage #2: 1-Bromo-2-bromomethyl-benzene In tetrahydrofuran for 4h; Etherification; Heating; Further stages.;	100%

: 3769-41-3
3-Benzyloxyphenol

: 59142-68-6
2-bromo-4-fluorobenzaldehyde

: 1196474-64-2
4-(3-benzyloxy-phenoxy)-2-bromo-benzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 16h; Product distribution / selectivity;	100%
With caesium carbonate In N,N-dimethyl-formamide at 80℃;

: 3769-41-3
3-Benzyloxyphenol

: 1498-51-7
ethyl phosphodichloridite

: bis(3-(benzyloxy)phenyl) ethyl phosphate

Conditions

Conditions	Yield
Stage #1: 3-Benzyloxyphenol With sodium hydride In tetrahydrofuran Stage #2: ethyl phosphodichloridite In tetrahydrofuran Reflux;	98%
With sodium hydride In tetrahydrofuran Reflux;	98%

: 94878-41-8
1-(diphenylmethyl)-1H-indole-2,3-dione

: 3769-41-3
3-Benzyloxyphenol

: 1221748-90-8
3-[4-(benzyloxy)-2-hydroxyphenyl]-1-(diphenylmethyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one

Conditions

Conditions	Yield
Stage #1: 3-Benzyloxyphenol With isopropylmagnesium chloride In tetrahydrofuran at 0℃; Stage #2: 1-(diphenylmethyl)-1H-indole-2,3-dione In dichloromethane at 0 - 20℃; Stage #3: With water; ammonium chloride In dichloromethane	97%
Stage #1: 3-Benzyloxyphenol With isopropylmagnesium chloride In tetrahydrofuran at 0℃; Stage #2: 1-(diphenylmethyl)-1H-indole-2,3-dione In tetrahydrofuran; dichloromethane at 0 - 20℃; for 16h; Stage #3: With ammonium chloride In tetrahydrofuran; dichloromethane	97%

: 3769-41-3
3-Benzyloxyphenol

: 106-95-6
allyl bromide

: 1448791-90-9
1-(allyloxy)-3-(benzyloxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 12h; Inert atmosphere;	95.2%

: 3769-41-3
3-Benzyloxyphenol

: 2905-23-9
2-chlorophenylsulfonyl chloride

: 189339-58-0
2-Chlorobenzenesulfonic acid 3-benzyloxyphenyl ester

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane	95%

: 96994-77-3
3-iodopropionaldehyde dimethylacetal

: 3769-41-3
3-Benzyloxyphenol

: 144852-07-3
3-(3-benzyloxyphenoxy)propionaldehyde dimethyl acetal

Conditions

Conditions	Yield
Stage #1: 3-Benzyloxyphenol With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; Stage #2: 3-iodopropionaldehyde dimethylacetal at 20℃;	93%
With potassium hydroxide 1) THF, r.t., 2) THF, reflux; Yield given. Multistep reaction;
With potassium hydroxide In tetrahydrofuran
With potassium hydroxide In tetrahydrofuran for 17h; Heating;

: 3769-41-3
3-Benzyloxyphenol

: 3282-30-2
pivaloyl chloride

: 1067665-45-5
3-(benzyloxy)phenyl pivalate

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	93%

: 3769-41-3
3-Benzyloxyphenol

: 107-30-2
chloromethyl methyl ether

: 235091-19-7
3-Benzyloxy-1-methoxymethoxybenzene

Conditions

Conditions	Yield
Stage #1: 3-Benzyloxyphenol With sodium hydride In tetrahydrofuran at 20℃; for 0.166667h; Metallation; Stage #2: chloromethyl methyl ether In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 1h; Etherification;	91%
With N-ethyl-N,N-diisopropylamine In dichloromethane

: 96-19-5
1,2,3-trichloropropene

: 3769-41-3
3-Benzyloxyphenol

: C16H14Cl2O2

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide	91%

: 3769-41-3
3-Benzyloxyphenol

: 96-34-4
methyl chloroacetate

: 135360-30-4
(3-Benzyloxy-phenoxy)-acetic acid methyl ester

Conditions

Conditions	Yield
With potassium carbonate; sodium iodide In acetone for 10h; Heating;	90%

: 3769-41-3
3-Benzyloxyphenol

: 16420-13-6
N,N-Dimethylthiocarbamoyl chloride

: 883718-66-9
O-(3-benzyloxy)phenyldimethylthiocarbamate

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide at 20℃; for 2h;	90%

: 3769-41-3
3-Benzyloxyphenol

: 106-96-7
propargyl bromide

: 70371-58-3
1-(benzyloxy)-3-(prop-2-yn-1-yloxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide; toluene at 20℃; for 7h; Inert atmosphere;	90%
With potassium carbonate In N,N-dimethyl-formamide; toluene at 20℃; for 7h; Inert atmosphere;	90%
With potassium carbonate In acetone for 24h; Inert atmosphere; Reflux;	77%

: 3769-41-3
3-Benzyloxyphenol

: C14H7ClF4O2

: C27H18F4O4

Conditions

Conditions	Yield
Stage #1: C14H7ClF4O2 With thionyl chloride In dichloromethane at 20℃; for 5h; Stage #2: 3-Benzyloxyphenol With pyridine In dichloromethane at 20℃; for 48h;	89.7%

: 144292-54-6
4-(benzyloxy)-2,3-difluorobenzoic acid

: 3769-41-3
3-Benzyloxyphenol

: 3-(benzyloxy)phenyl-4-(benzyloxy)-2,3-difluorobenzoate

Conditions

Conditions	Yield
Stage #1: 4-(benzyloxy)-2,3-difluorobenzoic acid With thionyl chloride In dichloromethane for 5h; Reflux; Stage #2: 3-Benzyloxyphenol With pyridine In dichloromethane at 20℃; for 48h;	89.7%

: 3769-41-3
3-Benzyloxyphenol

: 106817-35-0
4-(4-dodecyloxybenzoyloxy)benzoic acid

: 791849-96-2
1-benzyloxyphenylene-3-(4-n-dodecyloxybenzoyloxy-4-benzoate)

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane	89%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃;
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24h;
With dmap; dicyclohexyl-carbodiimide In dichloromethane

: 50-00-0
formaldehyd

: 3769-41-3
3-Benzyloxyphenol

: 52085-14-0
4-benzoxy-salicylaldehyde

Conditions

Conditions	Yield
With triethylamine; magnesium chloride In tetrahydrofuran Inert atmosphere; Reflux; regioselective reaction;	88%

: 3769-41-3
3-Benzyloxyphenol

: 51359-78-5
4-(bromomethyl)benzaldehyde

: 4-((3-(benzyloxy)phenoxy)methyl)benzaldehyde

Conditions

Conditions	Yield
Stage #1: 3-Benzyloxyphenol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.283333h; Inert atmosphere; Sonication; Stage #2: 4-(bromomethyl)benzaldehyde In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;	88%

: 3769-41-3
3-Benzyloxyphenol

: 1-(5-cyano-2-methyl-5,5-diphenylpentan-2-yl)azetidin-3-yl methanesulfonate monohydrochloride

: 931410-46-7
5-{3-[3-(benzyloxy)phenoxy]azetidine-1-yl}-5-methyl-2,2-diphenylhexanenitrile

Conditions

Conditions	Yield
Stage #1: 1-(5-cyano-2-methyl-5,5-diphenylpentan-2-yl)azetidin-3-yl methanesulfonate monohydrochloride With caesium carbonate In acetonitrile at 20℃; Stage #2: 3-Benzyloxyphenol In acetonitrile at 75 - 80℃; for 12h;	87%

: 3769-41-3
3-Benzyloxyphenol

: 145839-40-3
2-(2-(2-(4-tritylphenoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate

: 189118-52-3
1-(2-{2-[2-(tritylphenoxy)ethoxy]ethoxy}ethoxy)-3-(benzyloxy)benzene

Conditions

Conditions	Yield
With potassium carbonate; lithium bromide In acetonitrile for 96h; Heating;	84%

: 3769-41-3
3-Benzyloxyphenol

: 56955-73-8
4-((4-(heptyloxy)benzoyl)oxy)benzoic acid

: 1331828-92-2
4-((3-(benzyloxy)phenoxy)carbonyl)phenyl 4-(heptyloxy)benzoate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 12h;	84%

: 53963-10-3
2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran

: 3769-41-3
3-Benzyloxyphenol

: 2-((6-(3-(benzyloxy)phenoxy)hexyl)oxy)tetrahydro-2H-pyran

Conditions

Conditions	Yield
With caesium carbonate In acetone at 70℃;	83%
With caesium carbonate In acetone at 70℃;	83%

: 3769-41-3
3-Benzyloxyphenol

: 186087-99-0
diphenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside phosphate

: 2-(2',3',4',6'-tetra-O-benzyl-α-D-mannopyranosyl)-5-benzyloxyphenol

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 20℃; for 1h;	82%
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 0 - 20℃; for 1h;	82%

: 629-03-8
1 ,6-dibromohexane

: 3769-41-3
3-Benzyloxyphenol

: 1-(benzyloxy)-3-(6-bromohexyloxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In acetone at 50℃; for 24h;	82%

3-Benzyloxyphenol Chemical Properties

The molecular formula of 3-Benzyloxyphenol(3769-41-3) is C₁₃H₁₂O₂ and its formula weight is 200.23.
3-Benzyloxyphenol(3769-41-3) has a melting point of 50°C. The boiling point is 200 °C / 5mmHg.
The chemical synonyms of 3-Benzyloxyphenol(3769-41-3) are 3-(BENZYLOXY)PHENOL;M-(BENZYLOXY)PHENOL;TIMTEC-BB SBB008506;RESORCINOL MONOBENZYL ETHER;Phenol, 3-(phenylmethoxy)-;MONOBENZYL RESOURCINOL;3-(Benzyloxy)phenol ,95%
The molecular structure of 3-Benzyloxyphenol(3769-41-3):

3-Benzyloxyphenol Safety Profile

Risk Statements 36/37/38
Safety Statements 26-36/37/39

Product Name

3-Benzyloxyphenol

Synthetic route

3-Benzyloxyphenol Chemical Properties

3-Benzyloxyphenol Safety Profile

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