3,4-DIMETHOXY-2-HYDROXYBENZALDEHYDE

The Benzaldehyde,2-hydroxy-3,4-dimethoxy- is an organic compound with the formula C₉H₁₀O₄. Its CAS registry number is 19283-70-6. The IUPAC name of this chemical is 2-Hydroxy-3,4-dimethoxybenzaldehyde. In addition, the molecular weight is 182.17. It belongs to the product categories of Aromatic Aldehydes & Derivatives (substituted); Pharmacetical. Its EINECS registry number is 242-936-4.

Physical properties about Benzaldehyde,2-hydroxy-3,4-dimethoxy-are: (1)ACD/LogP: 1.49; (2)#of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.48; (4)ACD/LogD (pH 7.4): 1.34; (5)ACD/BCF (pH 5.5): 7.91; (6)ACD/BCF (pH 7.4): 5.68; (7)ACD/KOC (pH 5.5): 152.66; (8)ACD/KOC (pH 7.4): 109.6; (9)#H bond acceptors: 4; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 44.76 Å²; (13)Index of Refraction: 1.567; (14)Molar Refractivity: 48.24 cm³; (15)Molar Volume: 147.5 cm³; (16)Polarizability: 19.12×10^-24 cm³; (17)Surface Tension: 44.3 dyne/cm; (18)Density: 1.234 g/cm³; (19)Flash Point: 114.5 °C; (20)Enthalpy of Vaporization: 55.02 kJ/mol; (21)Boiling Point: 289.7 °C at 760 mmHg; (22)Vapour Pressure: 0.00124 mmHg at 25 °C.

Preparation of Benzaldehyde,2-hydroxy-3,4-dimethoxy-: this chemical can be prepared by 2,3,4-trimethoxy-benzaldehyde. This reaction needs reagents AlCl₃ and toluene. The reaction equation is as followed：

Uses of Benzaldehyde,2-hydroxy-3,4-dimethoxy-: it can be used to produce other chemicals. For example, it is used to produce 6,7-dimethoxy-2-nitro-benzofuran with bromo-nitro-methane. The reaction occurs with reagent K₂CO₃ and other condition of heating for 5 hours. The solvent of this chemical is acetone. The yield is 48 %. The reaction equation is as followed:

You can still convert the following datas into molecular structure:
(1) SMILES: O=Cc1c(O)c(OC)c(OC)cc1
(2) InChI: InChI=1/C9H10O4/c1-12-7-4-3-6(5-10)8(11)9(7)13-2/h3-5,11H,1-2H3
(3) InChIKey: UIOMNPYQUBMBOJ-UHFFFAOYAY