3-hydroxy-2,4-dimethoxybenzaldehyde

The Benzaldehyde,3-hydroxy-2,4-dimethoxy- is an organic compound with the formula C₉H₁₀O₄. Its CAS registry number is 32246-34-7. The IUPAC name of this chemical is 3-Hydroxy-2,4-dimethoxybenzaldehyde. In addition, the molecular weight is 182.1733. Its EINECS registry number is 250-970-6.

Physical properties about Benzaldehyde,3-hydroxy-2,4-dimethoxy- are: (1)ACD/LogP: 0.85; (2)#of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.84; (4)ACD/LogD (pH 7.4): 0.84; (5)ACD/BCF (pH 5.5): 2.58; (6)ACD/BCF (pH 7.4): 2.55; (7)ACD/KOC (pH 5.5): 68.63; (8)ACD/KOC (pH 7.4): 67.68; (9)#H bond acceptors: 4; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 44.76 Å²; (13)Index of Refraction: 1.567; (14)Molar Refractivity: 48.24 cm³; (15)Molar Volume: 147.5 cm³; (16)Polarizability: 19.12×10^-24 cm³; (17)Surface Tension: 44.3 dyne/cm; (18)Density: 1.234 g/cm³; (19)Flash Point: 132.4 °C; (20)Enthalpy of Vaporization: 59.19 kJ/mol; (21)Boiling Point: 327 °C at 760 mmHg; (22)Vapour Pressure: 0.000109 mmHg at 25 °C.

Preparation of Benzaldehyde,3-hydroxy-2,4-dimethoxy-: this chemical can be prepared by diazomethane with 2,3-dihydroxy-4-methoxy-benzaldehyde. This reaction needs solvent diethyl ether at 0 °C for 60 min. The yield is 40 %. The reaction equation is as followed:

Uses of Benzaldehyde,3-hydroxy-2,4-dimethoxy-: it can be used to produce other chemicals. For example, it is used to produce 3-benzyloxy-2,4-dimethoxybenzaldehyde with chloromethyl-benzene. The reaction occurs with reagent Na₂CO₃ and other condition of heating for 24 hours. The solvent of this reaction is ethanol. The yield is 88 %. The reaction equation is as followed:

You can still convert the following datas into molecular structure:
(1) SMILES: O=Cc1c(OC)c(O)c(OC)cc1
(2) InChI: InChI=1/C9H10O4/c1-12-7-4-3-6(5-10)9(13-2)8(7)11/h3-5,11H,1-2H3
(3) InChIKey: COBXDAOIDYGHGK-UHFFFAOYAA