2-FLUORO-5-METHYLANISOLE

The Benzene,1-fluoro-2-methoxy-4-methyl-, with the CAS registry number 63762-78-7, is also known as 2-Fluoro-5-methylphenyl methyl ether. It belongs to the product categories of Aromatic Hydrocarbons (substituted) & Derivatives; Aromatic Ethers; Ethers; Organic Building Blocks; Oxygen Compounds. This chemical's molecular formula is C₈H₉FO and molecular weight is 140.15. Its systematic name is called 1-fluoro-2-methoxy-4-methylbenzene.

Physical properties of Benzene,1-fluoro-2-methoxy-4-methyl-: (1)ACD/LogP: 2.60; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.6; (4)ACD/LogD (pH 7.4): 2.6; (5)ACD/BCF (pH 5.5): 55.28; (6)ACD/BCF (pH 7.4): 55.28; (7)ACD/KOC (pH 5.5): 615.07; (8)ACD/KOC (pH 7.4): 615.07; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.475; (13)Molar Refractivity: 37.75 cm³; (14)Molar Volume: 133.9 cm³; (15)Surface Tension: 28.2 dyne/cm; (16)Density: 1.046 g/cm³; (17)Flash Point: 63.7 °C; (18)Enthalpy of Vaporization: 40.16 kJ/mol; (19)Boiling Point: 182.5 °C at 760 mmHg; (20)Vapour Pressure: 1.1 mmHg at 25°C.

Preparation: this chemical can be prepared by sulfuric acid dimethyl ester and 4-fluoro-3-hydroxytoluene. This reaction will need reagent K₂CO₃ and solvent acetone. The reaction time is 5 hours by heating. The yield is about %.

Uses of Benzene,1-fluoro-2-methoxy-4-methyl-: it can be used to produce 4-fluoro-3-methoxybenzoic acid at temperature of 50 °C. This reaction will need reagent potassium permanganate, pyridine and solvent H₂O with reaction time of 3 hours. The yield is about 70%.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing.

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1ccc(cc1OC)C
(2)InChI: InChI=1/C8H9FO/c1-6-3-4-7(9)8(5-6)10-2/h3-5H,1-2H3
(3)InChIKey: MOFZLPPSEOEXNJ-UHFFFAOYAJ