Product Name

  • Name

    2,2-DIMETHYLETHENYLBORONIC ACID

  • EINECS
  • CAS No. 14559-88-7
  • Article Data15
  • CAS DataBase
  • Density 0.952 g/cm3
  • Solubility
  • Melting Point 87 °C
  • Formula C4H9BO2
  • Boiling Point 190.6 °C at 760 mmHg
  • Molecular Weight 99.9253
  • Flash Point 69.1 °C
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 14559-88-7 (2,2-DIMETHYLETHENYLBORONIC ACID)
  • Hazard Symbols
  • Synonyms 1-Propene-1-boronicacid, 2-methyl- (7CI,8CI);Boronic acid, (2-methyl-1-propenyl)- (9CI);2-Methylprop-1-enylboronic acid;
  • PSA 40.46000
  • LogP -0.03540

Synthetic route

Triisopropyl borate
5419-55-6

Triisopropyl borate

2-methyl-1-propenylbromide
3017-69-4

2-methyl-1-propenylbromide

water
7732-18-5

water

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
Stage #1: Triisopropyl borate; 2-methyl-1-propenylbromide With lithium In tetrahydrofuran at -50 - -40℃; Inert atmosphere;
Stage #2: water With hydrogenchloride In tetrahydrofuran at 0 - 10℃; pH=3 - 4; Temperature; Reagent/catalyst; Inert atmosphere;
60.3%
2-methylpropen-1-ylmagnesium bromide
38614-36-7

2-methylpropen-1-ylmagnesium bromide

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
With Trimethyl borate; lithium chloride In tetrahydrofuran; diethyl ether at -78 - 20℃; Inert atmosphere;55%
With Trimethyl borate In diethyl ether at -78 - 20℃;41%
Stage #1: 2-methylpropen-1-ylmagnesium bromide With Trimethyl borate In tetrahydrofuran at -78 - 20℃; Inert atmosphere;
Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0 - 20℃; for 1.5h; Inert atmosphere;
Stage #1: 2-methylpropen-1-ylmagnesium bromide With Trimethyl borate In tetrahydrofuran at -70 - 20℃; for 3.58333h; Inert atmosphere;
Stage #2: With N-methyliminodiacetic acid In tetrahydrofuran; dimethyl sulfoxide at 120 - 150℃; for 1h; Inert atmosphere;
Stage #3: With water; sodium hydroxide In tetrahydrofuran at 20℃; for 0.25h;
2-methyl-1-propenylbromide
3017-69-4

2-methyl-1-propenylbromide

chloro-bis(dimethylamino)borane
6562-41-0

chloro-bis(dimethylamino)borane

water
7732-18-5

water

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
Stage #1: 2-methyl-1-propenylbromide; chloro-bis(dimethylamino)borane With lithium In tetrahydrofuran at -78 - -70℃; Inert atmosphere;
Stage #2: water With hydrogenchloride In tetrahydrofuran at 0 - 10℃; pH=3 - 4; Inert atmosphere;
46.9%
Trimethyl borate
121-43-7

Trimethyl borate

2-methylprop-1-enyllithium
29917-94-0

2-methylprop-1-enyllithium

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
und anschliessend mit wss.HCl;
Trimethyl borate
121-43-7

Trimethyl borate

2-methylpropen-1-ylmagnesium bromide
38614-36-7

2-methylpropen-1-ylmagnesium bromide

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

tris(ethylenedioxyboryl)methane
59278-44-3

tris(ethylenedioxyboryl)methane

acetone
67-64-1

acetone

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
(i) MeLi, Et2O, THF, CH2Cl2, (ii) /BRN= 635680/; Multistep reaction;
Trimethyl borate
121-43-7

Trimethyl borate

2-methyl-propenyl magnesium halide

2-methyl-propenyl magnesium halide

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
und Erwaermen des Reaktionsprodukts mit wss.H2SO4;
C10H21BO2

C10H21BO2

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
With water; ammonium chloride In pentane at 20℃; for 0.5h;
C6H13BO2
90011-02-2

C6H13BO2

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

Conditions
ConditionsYield
With hydrogenchloride; water In tetrahydrofuran at 0 - 20℃; for 1.5h;
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

methyl 3-bromo-4-(tetrahydro-2H-pyran-2-yloxy)benzoate
1142224-41-6

methyl 3-bromo-4-(tetrahydro-2H-pyran-2-yloxy)benzoate

methyl 3-(2-methyl-1-propenyl)-4-(tetrahydro-2H-pyran-2-yloxy)benzoate
1142225-87-3

methyl 3-(2-methyl-1-propenyl)-4-(tetrahydro-2H-pyran-2-yloxy)benzoate

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate In water; N,N-dimethyl-formamide at 70℃; for 23h; Inert atmosphere;100%
With potassium phosphate; 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl; palladium diacetate In water; N,N-dimethyl-formamide at 70℃; for 23h; Suzuki Coupling; Inert atmosphere;100%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(E)-4-(pyrazin-2-yl)but-3-en-2-one
1414846-58-4

(E)-4-(pyrazin-2-yl)but-3-en-2-one

6-methyl-4-(pyrazin-2-yl)hept-5-en-2-one

6-methyl-4-(pyrazin-2-yl)hept-5-en-2-one

Conditions
ConditionsYield
With (R)-3,3’-bis(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,1’-binaphthyl-2,2’-diol; magnesium 2-methylpropan-2-olate In toluene at 70℃; for 8h; Molecular sieve; Inert atmosphere; enantioselective reaction;99%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(E)-4-(2,4,6-trimethoxyphenyl)but-3-en-2-one
42811-79-0

(E)-4-(2,4,6-trimethoxyphenyl)but-3-en-2-one

6-methyl-4-(2,4,6-trimethoxyphenyl)hept-5-en-2-one

6-methyl-4-(2,4,6-trimethoxyphenyl)hept-5-en-2-one

Conditions
ConditionsYield
With (R)-3,3’-bis(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,1’-binaphthyl-2,2’-diol; magnesium 2-methylpropan-2-olate In toluene at 115℃; for 1h; Molecular sieve; Inert atmosphere; enantioselective reaction;99%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(E)-4-(2-thienyl)but-3-en-2-one
874-83-9, 33603-63-3

(E)-4-(2-thienyl)but-3-en-2-one

6-methyl-4-(thiophen-2-yl)hept-5-en-2-one

6-methyl-4-(thiophen-2-yl)hept-5-en-2-one

Conditions
ConditionsYield
With (R)-3,3’-bis(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,1’-binaphthyl-2,2’-diol; magnesium 2-methylpropan-2-olate In toluene at 115℃; for 2h; Molecular sieve; Inert atmosphere; enantioselective reaction;99%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(Z)-7-[(3R)-3-(tert-butyldimethylsilanyloxy)-5-oxo-cyclopent-1-enyl]hept-5-enoic acid isopropyl ester
474944-36-0

(Z)-7-[(3R)-3-(tert-butyldimethylsilanyloxy)-5-oxo-cyclopent-1-enyl]hept-5-enoic acid isopropyl ester

(Z)-7-[(2R,3R)-3-(tert-butyl-dimethylsilanyloxy)-2-(2-methyl-prop-1-enyl)-5-oxo-cyclopentyl]hept-5-enoic acid isopropyl ester

(Z)-7-[(2R,3R)-3-(tert-butyl-dimethylsilanyloxy)-2-(2-methyl-prop-1-enyl)-5-oxo-cyclopentyl]hept-5-enoic acid isopropyl ester

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; potassium hydroxide In methanol; water at 3℃; for 72h; Temperature; Inert atmosphere; diastereoselective reaction;99%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide
1124382-78-0

N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide

N-[5-(2-methylprop-1-en-1-yl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide dihydrochloride

N-[5-(2-methylprop-1-en-1-yl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide dihydrochloride

Conditions
ConditionsYield
Stage #1: 2,2-dimethylethenylboronic acid; N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide With cesium fluoride; bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran; water at 120℃; Suzuki-Miyaura reaction;
Stage #2: With hydrogenchloride In diethyl ether; dichloromethane
96%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(E)-4-(quinolin-2-yl)but-3-en-2-one
137479-63-1

(E)-4-(quinolin-2-yl)but-3-en-2-one

6-methyl-4-(quinolin-2-yl)hept-5-en-2-one

6-methyl-4-(quinolin-2-yl)hept-5-en-2-one

Conditions
ConditionsYield
With (R)-3,3’-bis(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,1’-binaphthyl-2,2’-diol; magnesium 2-methylpropan-2-olate In toluene at 70℃; for 5h; Molecular sieve; Inert atmosphere; enantioselective reaction;96%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(E)-4-(1-methyl-1H-imidazol-2-yl)but-3-en-2-one
1414846-63-1

(E)-4-(1-methyl-1H-imidazol-2-yl)but-3-en-2-one

6-methyl-4-(1-methyl-1H-imidazol-2-yl)hept-5-en-2-one

6-methyl-4-(1-methyl-1H-imidazol-2-yl)hept-5-en-2-one

Conditions
ConditionsYield
With (R)-3,3’-bis(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,1’-binaphthyl-2,2’-diol; magnesium 2-methylpropan-2-olate In toluene at 115℃; for 12h; Molecular sieve; Inert atmosphere; enantioselective reaction;94%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

2-(3-bromo-2-methylbenzoylamino)indan-2-carboxylic acid ethyl ester
1092449-74-5

2-(3-bromo-2-methylbenzoylamino)indan-2-carboxylic acid ethyl ester

2-[2-methyl-3-(2-methyl-1-propenyl)benzoylamino]indan-2-carboxylic acid ethyl ester
1092449-75-6

2-[2-methyl-3-(2-methyl-1-propenyl)benzoylamino]indan-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium(0) In water; N,N-dimethyl-formamide at 110℃; for 5h;92%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

4-(pyridin-4-yl)-3-buten-2-one
94445-75-7

4-(pyridin-4-yl)-3-buten-2-one

6-methyl-4-(pyridin-4-yl)hept-5-en-2-one

6-methyl-4-(pyridin-4-yl)hept-5-en-2-one

Conditions
ConditionsYield
With (R)-3,3’-bis(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,1’-binaphthyl-2,2’-diol; magnesium 2-methylpropan-2-olate In toluene at 115℃; for 22h; Molecular sieve; Inert atmosphere; enantioselective reaction;91%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(S)-(5-(hydroxymethyl)-1-tosyl-7-(((trifluoromethyl)sulfonyl)oxy)-1,2,3,5-tetrahydrocyclopenta[f]indol-5-yl)methyl benzoate

(S)-(5-(hydroxymethyl)-1-tosyl-7-(((trifluoromethyl)sulfonyl)oxy)-1,2,3,5-tetrahydrocyclopenta[f]indol-5-yl)methyl benzoate

(S)-(5-(hydroxymethyl)-7-(2-methylprop-1-en-1-yl)-1-tosyl-1,2,3,5-tetrahydrocyclopenta[f]indol-5-yl)methyl benzoate

(S)-(5-(hydroxymethyl)-7-(2-methylprop-1-en-1-yl)-1-tosyl-1,2,3,5-tetrahydrocyclopenta[f]indol-5-yl)methyl benzoate

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate In water; toluene at 50℃; for 6h; Inert atmosphere; Darkness;90%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

1,1-dimethylethyl 9-bromo-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate
1055880-27-7

1,1-dimethylethyl 9-bromo-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate

tert-butyl 9-(2-methylpropa-1-ene-1-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate
1055880-88-0

tert-butyl 9-(2-methylpropa-1-ene-1-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 85℃; for 12h; Inert atmosphere; Saturated solution;89.1%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(E)-4-pyridin-3-ylbut-3-en-2-one
28447-16-7, 94445-77-9

(E)-4-pyridin-3-ylbut-3-en-2-one

6-methyl-4-(pyridin-3-yl)hept-5-en-2-one

6-methyl-4-(pyridin-3-yl)hept-5-en-2-one

Conditions
ConditionsYield
With (1R,3'r)-3,3'-bis(perfluorophenyl)[1,1'-binaphthalene]-2,2'-diol; magnesium 2-methylpropan-2-olate In toluene at 115℃; for 15h; Molecular sieve; Inert atmosphere; enantioselective reaction;88%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

benzo[e][1,2,3]oxathiazine 2,2-dioxide
71730-46-6

benzo[e][1,2,3]oxathiazine 2,2-dioxide

(R)-4-(2-methylprop-1-en-1-yl)-3,4-dihydrobenzo[e][1,2,3]oxathiazine 2,2-dioxide

(R)-4-(2-methylprop-1-en-1-yl)-3,4-dihydrobenzo[e][1,2,3]oxathiazine 2,2-dioxide

Conditions
ConditionsYield
With nickel(II) perchlorate hexahydrate; C30H28NOP In 2,2,2-trifluoroethanol at 70℃; for 48h;87%
With (1R,1’R,2S,2’S)-2,2’-di-tert-butyl-2,3,2’,3’-tetrahydro-1H,1‘H-(1,1‘)biisophosphindolyl; potassium carbonate; cobalt(II) bromide In tetrahydrofuran at 70℃; for 24h; Inert atmosphere; enantioselective reaction;70%
1-Benzenesulfonyl-5-bromo-3-[2-(1-methyl-piperidin-4-yl)-thiazol-4-yl]-1H pyrrolo[2,3-b]pyridine
1046793-45-6

1-Benzenesulfonyl-5-bromo-3-[2-(1-methyl-piperidin-4-yl)-thiazol-4-yl]-1H pyrrolo[2,3-b]pyridine

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

1-Benzenesulfonyl-3-[2-(1-methyl-piperidin-4-yl)-thiazol-4-yl]-5-(2-methyl-propenyl)-1H-pyrrolo[2,3-b]pyridine

1-Benzenesulfonyl-3-[2-(1-methyl-piperidin-4-yl)-thiazol-4-yl]-5-(2-methyl-propenyl)-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In ethanol; water; toluene Suzuki-Miaura reaction; Heating / reflux;86%
With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In ethanol; water; toluene at 110℃; for 1.5h; Suzuki Coupling;86%
4-(1-Benzenesulfonyl-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-thiazole-2-carboxylic acid ethyl ester
1046793-41-2

4-(1-Benzenesulfonyl-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-thiazole-2-carboxylic acid ethyl ester

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

4-[1-Benzenesulfonyl-5-(2-methyl-propenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-thiazole-2-carboxylic acid ethyl ester

4-[1-Benzenesulfonyl-5-(2-methyl-propenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-thiazole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In ethanol; water; toluene at 110℃; for 1.5h; Suzuki-Miaura reaction; Heating / reflux;85%
With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In ethanol; water; toluene at 110℃; for 1.5h; Suzuki Coupling;85%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

indole-2,3-dione
91-56-5

indole-2,3-dione

(S)-3-hydroxy-3-(2-methylprop-1-en-1-yl)indolin-2-one

(S)-3-hydroxy-3-(2-methylprop-1-en-1-yl)indolin-2-one

Conditions
ConditionsYield
With (1R,1’R,2S,2’S)-2,2’-di-tert-butyl-2,3,2’,3’-tetrahydro-1H,1‘H-(1,1‘)biisophosphindolyl; potassium carbonate; cobalt(II) bromide In tetrahydrofuran at 70℃; for 40h; Inert atmosphere; enantioselective reaction;80%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

N-methyl-2-iodoaniline
57056-93-6

N-methyl-2-iodoaniline

N-methyl-N-[2-(2-methylpropenyl)phenyl]amine
41652-76-0

N-methyl-N-[2-(2-methylpropenyl)phenyl]amine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene at 80℃; for 12h;80%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

tert-butyl 2-[3-acetyl-5-bromo-7-(prop-2-en-1-yl)indazol-1-yl]acetate

tert-butyl 2-[3-acetyl-5-bromo-7-(prop-2-en-1-yl)indazol-1-yl]acetate

tert-butyl 2-(3-acetyl-7-allyl-5-(2-methylprop-1-en-1-yl)-1H-indazol-1-yl)acetate

tert-butyl 2-(3-acetyl-7-allyl-5-(2-methylprop-1-en-1-yl)-1H-indazol-1-yl)acetate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 90℃; for 16h; Inert atmosphere;79.9%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

(3S,8aR)-5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxylic acid methyl ester

(3S,8aR)-5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxylic acid methyl ester

(3S,8aR)-6-(2-methylprop-1-en-1-yl)-5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxy methyl ester

(3S,8aR)-6-(2-methylprop-1-en-1-yl)-5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxy methyl ester

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane; water at 100℃; for 12h; Sealed tube; Inert atmosphere;78.1%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

2-(2-iodo-3-methyl-benzoylamino)-indane-2-carboxylic acid ethyl ester
1092447-82-9

2-(2-iodo-3-methyl-benzoylamino)-indane-2-carboxylic acid ethyl ester

2-[3-methyl-2-(2-methyl-propenyl)-benzoylamino]-indan-2-carboxylic acid ethyl ester
1092447-84-1

2-[3-methyl-2-(2-methyl-propenyl)-benzoylamino]-indan-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With caesium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane; water at 110℃; for 2h; Microwave irradiation;78%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

anthranilic acid amide
28144-70-9

anthranilic acid amide

2-(2-methylprop-1-en-1-yl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

2-(2-methylprop-1-en-1-yl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

Conditions
ConditionsYield
With dibromobis(triphenylphosphine)nickel(II); triethylamine; palladium dichloride In ethanol at 20℃; for 2h; Green chemistry; chemoselective reaction;75%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

methyl (3S,9aS)-6-bromo-5-oxo-2,3,5,8,9,9a-hexahydro-1H-pyrrolo[1,2-a]azepine-3-carboxylate

methyl (3S,9aS)-6-bromo-5-oxo-2,3,5,8,9,9a-hexahydro-1H-pyrrolo[1,2-a]azepine-3-carboxylate

(3S,9aS)-6-(2-methylprop-1-en-1-yl)-5-oxo-2,3,5,8,9,9a-hexahydro-1H-pyrrolo[1,2-a]azepine-3-carboxylic acid methyl ster

(3S,9aS)-6-(2-methylprop-1-en-1-yl)-5-oxo-2,3,5,8,9,9a-hexahydro-1H-pyrrolo[1,2-a]azepine-3-carboxylic acid methyl ster

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,4-dioxane; water at 100℃; for 12h; Sealed tube; Inert atmosphere;74.6%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

tris(2-methylpropene-1-yl) boroxine
1010113-27-5

tris(2-methylpropene-1-yl) boroxine

Conditions
ConditionsYield
With magnesium sulfite In pyridine; diethyl ether at 20℃;73%
byproducts: H2O; dehydration;;
byproducts: H2O; dehydration;;
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

5-fluoro-2-(2-iodo-3-methyl-benzoylamino)indan-2-carboxylic acid ethyl ester
1092446-64-4

5-fluoro-2-(2-iodo-3-methyl-benzoylamino)indan-2-carboxylic acid ethyl ester

5-fluoro-2-[3-methyl-2-(2-methyl-propenyl)-benzoylamino]-indan-2-carboxylic acid ethyl ester
1092447-88-5

5-fluoro-2-[3-methyl-2-(2-methyl-propenyl)-benzoylamino]-indan-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate; palladium anchored homogeneous catalyst, FibreCatPd(0) (4.84percentPd) In 1,4-dioxane; ethanol; water at 120℃; for 7h; Microwave irradiation;73%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

5,5-bis(hydroxymethyl)-1-tosyl-1,2,3,5-tetrahydrocyclopenta[f]indol-7-yl trifluormethansulfonate

5,5-bis(hydroxymethyl)-1-tosyl-1,2,3,5-tetrahydrocyclopenta[f]indol-7-yl trifluormethansulfonate

(7-(2-methylprop-1-en-1-yl)-1-tosyl-1,2,3,5-tetrahydrocyclopenta[f]indole-5,5-diyl)dimethanol

(7-(2-methylprop-1-en-1-yl)-1-tosyl-1,2,3,5-tetrahydrocyclopenta[f]indole-5,5-diyl)dimethanol

Conditions
ConditionsYield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate In water; toluene at 50℃; for 6h; Suzuki-Miyaura Coupling; Sonication; Darkness;71%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

3-methyl-3-phenylcyclopropene
65051-83-4

3-methyl-3-phenylcyclopropene

((1S,2R)-1-methyl-2-(2-methylprop-1-en-1-yl)cyclopropyl)benzene

((1S,2R)-1-methyl-2-(2-methylprop-1-en-1-yl)cyclopropyl)benzene

Conditions
ConditionsYield
With potassium carbonate; cobalt(II) chloride; [2R-[1(2'R*,5'R*),2a,5b]]-1,1'-(1,2-phenylene)bis[2,5-dimethylphospholane] In tetrahydrofuran at 70℃; for 12h; Inert atmosphere; Sealed tube; stereoselective reaction;70%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

C10H11BrN2O2

C10H11BrN2O2

C14H18N2O2

C14H18N2O2

Conditions
ConditionsYield
With palladium diacetate; cesium fluoride; tris-(o-tolyl)phosphine In 1,4-dioxane at 75℃; for 20h; Temperature; Solvent; Inert atmosphere;68.2%
2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

1-(4-bromo-2-chloro-phenyl)-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol
1615663-83-6

1-(4-bromo-2-chloro-phenyl)-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol

1-(2-chloro-4-(2-methylprop-1-en-1-yl)phenyl)-1-cyclopropyl-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol

1-(2-chloro-4-(2-methylprop-1-en-1-yl)phenyl)-1-cyclopropyl-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,2-dimethoxyethane; water at 90℃; for 14h;67%
4-(2-(4-(5-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-1H-pyrazol-1-yl)ethyl)morpholine
923584-14-9

4-(2-(4-(5-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-1H-pyrazol-1-yl)ethyl)morpholine

2,2-dimethylethenylboronic acid
14559-88-7

2,2-dimethylethenylboronic acid

1-Benzenesulfonyl-5-(2-methyl-propenyl)-3-[1-(2-morpholin-4-yl-ethyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine
923584-06-9

1-Benzenesulfonyl-5-(2-methyl-propenyl)-3-[1-(2-morpholin-4-yl-ethyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In ethanol; water; toluene for 3h; Suzuki-Miaura reaction; Heating / reflux;66%
With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride In ethanol; water; toluene at 115℃; for 3h; Suzuki Coupling;66%

Boronic acid,B-(2-methyl-1-propen-1-yl)- Specification

The Boronic acid,B-(2-methyl-1-propen-1-yl)-, with the CAS registry number 14559-88-7, is also known as 2,2-Dimethylethenylboronic acid. It belongs to the product category of Boronic Acids. This chemical's molecular formula is C4H9BO2 and molecular weight is 99.92. Its IUPAC name is called 2-methylprop-1-enylboronic acid.

Physical properties of Boronic acid,B-(2-methyl-1-propen-1-yl)-: (1)ACD/LogP: 1.51; (2)ACD/LogD (pH 5.5): 1.51; (3)ACD/LogD (pH 7.4): 1.51; (4)ACD/BCF (pH 5.5): 8.29; (5)ACD/BCF (pH 7.4): 8.26; (6)ACD/KOC (pH 5.5): 158.18; (7)ACD/KOC (pH 7.4): 157.59; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.427; (12)Molar Refractivity: 26.97 cm3; (13)Molar Volume: 104.9 cm3; (14)Surface Tension: 29.7 dyne/cm; (15)Density: 0.952 g/cm3; (16)Flash Point: 69.1 °C; (17)Enthalpy of Vaporization: 49.67 kJ/mol; (18)Boiling Point: 190.6 °C at 760 mmHg; (19)Vapour Pressure: 0.145 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: B(C=C(C)C)(O)O
(2)InChI: InChI=1S/C4H9BO2/c1-4(2)3-5(6)7/h3,6-7H,1-2H3
(3)InChIKey: FWJRSOGVYOIVOC-UHFFFAOYSA-N

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