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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

Isatin

Cas:91-56-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Isatin supplier in China

Cas:91-56-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 91-56-5 Isatin

Cas:91-56-5

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:White or

Isatin

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Indoline-2,3-dione

Cas:91-56-5

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract Isatin HACCP manufacturer

Cas:91-56-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

Isatin

Cas:91-56-5

Min.Order:5 Milligram

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Isatin in stock CAS NO.91-56-5

Cas:91-56-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Isatin

Cas:91-56-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Isatin The alias:2,3-Indolinedione; Indole-2,3-dione; 1H-indole-2,3-dione CAS NO:91-56-5 EINECS NO:202-077-8 Molecular formula:C8H5NO2 Molecular weight:147.13 Product Quality 12 years of chemical raw materials Mature operation of

Isatin/CAS:91-56-5/with best price

Cas:91-56-5

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Isatin Basic information Product Name: Isatin Synonyms: TIMTEC-BB SBB009100;O-AMINOPHENYLGLYOXALIC LACTIM;O-AMINOBENZOYLFORMIC ACID;O-AMINOBENZOYLFORMIC ANHYDRIDE;AKOS BBS-00003223;2,3-D

TIANFU-CHEM 91-56-5

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Isatin CAS 91-56-5

Cas:91-56-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 91-56-5 with fast shipping

Cas:91-56-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name:Isatin Other name:Indole-2,3-dione Synonyms:2,3-Indolinedione; 1H-Indole-2,3-dione Cas:91-56-5 Color:Orange-red single prism crystal Purity:98.0%min Molecular formula:C8H5NO2 Molecular weight:147.13 Melting point:193-195 &d

Isatin

Cas:91-56-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White powder Storage:Store in sealed containers at cool & dr

High quality best price of Isatin CAS NO 91-56-5

Cas:91-56-5

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Indole-2,3-dione 91-56-5

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: Isatin Synonyms: TIMTEC-BB SBB009100;O-AMINOPHENYLGLYOXALIC LACTIM;O-AMINOBENZOYLFORMIC ACID;O-AMINOBENZOYLFORMIC ANHYDRIDE;AKOS BBS-00003223;2,3-DIKETOINDOLINE;2,3-DIHYDROINDOLE-2,3-DIONE;2,3-INDOLEDIONE CAS: 91-56-5 MF: C8H5NO2

Isatin 91-56-5 98%

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Isatin CAS:91-56-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroi

Isatin CAS:91-56-5

Cas:91-56-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Indole-2,3-dione

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

Isatin CAS NO.91-56-5

Cas:91-56-5

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

China Wholesale bulk Isatin CAS 91-56-5

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:91-56-5

Cas:91-56-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

Isatin CAS: 91-56-5 Specification Item Standard Source Pure natural plant extract Sterilization method No irradiation Production Environment

Factory supply Isatin

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Isatin

Cas:91-56-5

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

Isatin(98%)

Cas:91-56-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Isatin CAS No. 91-56-5 Purity ≥98% , ≥95% Appearance Yellow and red crystal Molecular formula C8H5NO2 Molecular weight 1

Isatin

Cas:91-56-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Tribulin 91-56-5

Cas:91-56-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Isatin

Cas:91-56-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Isatin CAS NO.91-56-5

Cas:91-56-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Isatin

Cas:91-56-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

hydroxyimino-N-phenylacetamide
42366-35-8, 1769-41-1

hydroxyimino-N-phenylacetamide

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With sulfuric acid at 20 - 30℃; for 1.66667h; Temperature;99%
With sulfuric acid at 70℃; for 0.00277778h; Microwave irradiation;85%
With sulfuric acid at 65 - 90℃; for 0.5h;81.3%
2-(2-aminophenyl)-N-hexyl-2-oxoacetamide

2-(2-aminophenyl)-N-hexyl-2-oxoacetamide

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran; water at 20℃; for 5h;99%
Conditions
ConditionsYield
With ozone In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide at 70℃; for 24h; Solvent; Temperature; Large scale;98.2%
With potassium dichromate; sulfuric acid In water at 43℃; for 1.5h; Cooling;90%
With potassium dichromate; sulfuric acid In water at 43℃; for 1.5h;90%
With potassium dichromate; sulfuric acid In water at 43℃; for 1.5h; Cooling;90%
With potassium dichromate; sulfuric acid In water
3,3-dibromo-1-methoxy-2-oxindole
92635-28-4

3,3-dibromo-1-methoxy-2-oxindole

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With methanol Heating;98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With oxygen; Rose Bengal lactone In water; N,N-dimethyl-formamide for 48h; Inert atmosphere; Irradiation;98%
2-oxoindole
59-48-3

2-oxoindole

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With oxygen; copper(II) acetate monohydrate; potassium carbonate In N,N-dimethyl-formamide at 50℃; under 760.051 Torr; for 0.5h;95%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; oxygen In acetonitrile at 20℃; for 2h; Reagent/catalyst; Solvent;94%
With tert.-butylhydroperoxide In decane; acetonitrile at 80℃; for 0.285h; Catalytic behavior; Flow reactor; Green chemistry;90%
1-(2-iodoethynyl)-2-nitrobenzene
113783-27-0

1-(2-iodoethynyl)-2-nitrobenzene

A

2-iodo-3-oxo-3H-indole 1-oxide

2-iodo-3-oxo-3H-indole 1-oxide

B

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With copper(I) bromide dimethylsulfide complex In tetrahydrofuran for 16h; Inert atmosphere; Reflux;A 89%
B 8%
3-(tert-butylperoxy)-3-(4-methylbenzyl)indolin-2-one

3-(tert-butylperoxy)-3-(4-methylbenzyl)indolin-2-one

A

indole-2,3-dione
91-56-5

indole-2,3-dione

B

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

Conditions
ConditionsYield
With iron(III) chloride hexahydrate In acetonitrile at 100℃; Sealed tube;A 88%
B 89%
3-Iodo-1H-indole
26340-47-6

3-Iodo-1H-indole

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With N-iodo-succinimide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 25 - 35℃; for 6h;89%
N-(phenylthio)succinimide
14204-24-1

N-(phenylthio)succinimide

3-((4-chlorophenyl)thio)indolin-2-one

3-((4-chlorophenyl)thio)indolin-2-one

A

C20H14ClNOS2

C20H14ClNOS2

B

C20H14ClNOS2

C20H14ClNOS2

C

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With dihydroquinine In dichloromethane at -70℃; for 12h; Reagent/catalyst; enantioselective reaction;A n/a
B 88%
C 7%
With C29H44N3O3P In tetrahydrofuran at -70℃; for 84h; Reagent/catalyst; enantioselective reaction;A n/a
B 20%
C 71%
3-(tert-butylperoxy)-3-(4-methoxybenzyl)indolin-2-one

3-(tert-butylperoxy)-3-(4-methoxybenzyl)indolin-2-one

A

indole-2,3-dione
91-56-5

indole-2,3-dione

B

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

Conditions
ConditionsYield
With iron(III) chloride hexahydrate In acetonitrile at 100℃; Sealed tube;A 88%
B 82%
dioxindol
61-71-2

dioxindol

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With di-tert-butyl peroxide; copper diacetate In 1,4-dioxane at 120℃; Schlenk technique;87%
With ammonium nitrate; acetic acid
3-thiocyanatoindole
23706-25-4

3-thiocyanatoindole

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With cerium(III) chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In water; acetonitrile at 80℃; for 2.5h;87%
1-(Chloroacetyl)-1H-indole-2,3-dione
7218-25-9

1-(Chloroacetyl)-1H-indole-2,3-dione

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With thiourea In ethanol at 20 - 78℃;87%
Indole-3-carboxaldehyde
487-89-8

Indole-3-carboxaldehyde

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With cerium(III) chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In water; acetonitrile at 80℃; for 3h;85%
With Oxone; sodium chloride In water; acetonitrile at 50℃; for 2h; Green chemistry;84%
With indium(III) chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In water; acetonitrile at 80℃; for 2.5h;79%
With pyridinium chlorochromate In 1,2-dichloro-ethane at 80℃; for 4h;75%
1-indoline
496-15-1

1-indoline

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With o-iodosobenzoic acid; oxygen In dimethyl sulfoxide at 80℃; for 12h; Green chemistry;84%
With iodine pentoxide In dimethyl sulfoxide at 80℃; Temperature; Reagent/catalyst;76%
With tert.-butylhydroperoxide; iodine In dimethyl sulfoxide at 80℃; for 24h;30%
3-diazo-1,2,3,4-tetrahydro-2,4-dioxo-quinoline
7270-61-3

3-diazo-1,2,3,4-tetrahydro-2,4-dioxo-quinoline

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With copper(I) bromide In water; benzonitrile at 140℃; for 3h; Catalytic behavior; Reagent/catalyst; Solvent; Inert atmosphere;84%
1-(2-iodoethynyl)-2-nitrobenzene
113783-27-0

1-(2-iodoethynyl)-2-nitrobenzene

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In acetone at 60℃; for 4h; Inert atmosphere;83%
With copper(I) bromide dimethylsulfide complex In tetrahydrofuran for 16h; Reagent/catalyst; Solvent; Inert atmosphere; Reflux;60%
N-acetylindole
576-15-8

N-acetylindole

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With pyridinium chlorochromate In 1,2-dichloro-ethane at 80℃; for 3h;82%
N-phenylglycine ethyl ester
2216-92-4

N-phenylglycine ethyl ester

aniline
62-53-3

aniline

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With trifluoroacetic acid In ethanol at 70℃; for 10h;81.6%
3-(2-aminophenyl)-2-(dimethyl-1-sulfonylidene)-3-oxopropanenitrile

3-(2-aminophenyl)-2-(dimethyl-1-sulfonylidene)-3-oxopropanenitrile

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With Oxone In tetrahydrofuran; water at 20℃; for 0.166667h; Solvent; Inert atmosphere;81%
indole-2,3-dione
91-56-5

indole-2,3-dione

benzoic acid hydrazide
613-94-5

benzoic acid hydrazide

isatine 3-benzoylhydrazone
55711-62-1

isatine 3-benzoylhydrazone

Conditions
ConditionsYield
at 20℃; for 3h; Solid phase reaction; condensation;100%
In methanol for 0.5h; Heating;75%
With ethanol
In ethanol
indole-2,3-dione
91-56-5

indole-2,3-dione

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

indophenazine
243-59-4

indophenazine

Conditions
ConditionsYield
In 1,4-dioxane for 0.25h; Heating;100%
In acetic acid for 0.1h; Microwave irradiation;97%
With acetic acid Sealed tube; Microwave irradiation;95%
indole-2,3-dione
91-56-5

indole-2,3-dione

methyl iodide
74-88-4

methyl iodide

1-methyl-1H-indole-2,3-dione
2058-74-4

1-methyl-1H-indole-2,3-dione

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.0833333h;
Stage #2: methyl iodide In N,N-dimethyl-formamide; mineral oil at 25℃; for 12h;
100%
With potassium carbonate99%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;98%
indole-2,3-dione
91-56-5

indole-2,3-dione

isatoic anhydride
118-48-9

isatoic anhydride

Conditions
ConditionsYield
In acetonitrile at 20℃; for 24h; Inert atmosphere; Photolysis;100%
With tert.-butylhydroperoxide In water at 100℃; for 2h; Green chemistry;90%
With diphenyl diselenide; dihydrogen peroxide In N,N-dimethyl-formamide; acetonitrile at 25℃; for 8h; Solvent; Temperature; Reagent/catalyst; Time; Baeyer-Villiger Ketone Oxidation; Schlenk technique; Green chemistry;88%
indole-2,3-dione
91-56-5

indole-2,3-dione

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With sodium hydroxide In water at 20 - 50℃; for 1.5h;
Stage #2: With sulfuric acid; sodium nitrite In water at 0℃; for 1h;
Stage #3: With hydrogenchloride; tin(ll) chloride In water for 1.16667h;
100%
With sodium hydroxide; sulfuric acid; sulfur dioxide; sodium nitrite Reagens 4: Zinnchloruer;
With sulfuric acid; sodium nitrite danach SnCl2;
2-oxoindole
59-48-3

2-oxoindole

indole-2,3-dione
91-56-5

indole-2,3-dione

isoindigo
476-34-6

isoindigo

Conditions
ConditionsYield
With hydrogenchloride In acetic acid Heating;100%
With zirconium(IV) chloride In ethanol Reagent/catalyst; Solvent; Temperature; Reflux;91%
With hydrogenchloride In water; acetic acid for 3h; Reflux;88%
N,N'-diacetylpiperazin-2,5-dione
3027-05-2

N,N'-diacetylpiperazin-2,5-dione

indole-2,3-dione
91-56-5

indole-2,3-dione

3,6-bis(2-oxo-1,2-dihydroindol-3-ylidene)piperazine-2,5-dione
117563-29-8

3,6-bis(2-oxo-1,2-dihydroindol-3-ylidene)piperazine-2,5-dione

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 25℃; for 4h;100%
With triethylamine In N,N-dimethyl-formamide at 20℃; Knoevenagel condensation;90%
With triethylamine In N,N-dimethyl-formamide at 40℃; for 5h;
1-bromo-butane
109-65-9

1-bromo-butane

indole-2,3-dione
91-56-5

indole-2,3-dione

N-butylisatin
4290-91-9

N-butylisatin

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;100%
With caesium carbonate In N,N-dimethyl-formamide at 140℃; Microwave irradiation;93%
With potassium carbonate In N,N-dimethyl-formamide for 0.05h; microwave irradiation;90%
indole-2,3-dione
91-56-5

indole-2,3-dione

ethyl iodide
75-03-6

ethyl iodide

N-ethylisatin
4290-94-2

N-ethylisatin

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 72h;100%
With potassium carbonate In N,N-dimethyl-formamide for 0.05h; microwave irradiation;90%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;90%
indole-2,3-dione
91-56-5

indole-2,3-dione

ethyl bromoacetate
105-36-2

ethyl bromoacetate

(1-ethoxycarbonylmethyl)isatin
41042-21-1

(1-ethoxycarbonylmethyl)isatin

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With calcium hydride In N,N-dimethyl-formamide at 100℃; for 1h;
Stage #2: ethyl bromoacetate In N,N-dimethyl-formamide at 100℃; for 4h;
100%
Stage #1: indole-2,3-dione With aluminum oxide; potassium fluoride In acetonitrile for 0.0833333h;
Stage #2: ethyl bromoacetate In acetonitrile for 21h; Reflux;
97%
With KF-Celite In 2-methyltetrahydrofuran for 4h; Reflux; chemoselective reaction;93%
indole-2,3-dione
91-56-5

indole-2,3-dione

(3-Methyl-7-β-phenylethylxanthinyl-8) thioacetic hydrazide
107608-60-6

(3-Methyl-7-β-phenylethylxanthinyl-8) thioacetic hydrazide

(3-Methyl-2,6-dioxo-7-phenethyl-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-acetic acid [2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide
107608-68-4

(3-Methyl-2,6-dioxo-7-phenethyl-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-acetic acid [2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide

Conditions
ConditionsYield
With acetic acid In ethanol Heating;100%
indole-2,3-dione
91-56-5

indole-2,3-dione

propargyl bromide
106-96-7

propargyl bromide

1-prop-2-ynyl-1H-indole-2,3-dione
4290-87-3

1-prop-2-ynyl-1H-indole-2,3-dione

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With potassium carbonate In N,N-dimethyl-formamide for 0.333333h; Cooling with ice;
Stage #2: propargyl bromide In N,N-dimethyl-formamide at 20℃; for 3h;
100%
With potassium carbonate In N,N-dimethyl-formamide; toluene at 50℃; for 0.0833333h; Solvent; Time; Microwave irradiation;97.2%
With KF-Celite In 2-methyltetrahydrofuran for 3h; Reflux; chemoselective reaction;95%
4'-ethyl-1',4',7',8'-tetrahydro-4'-hydroxy-3'H,10'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione
102978-41-6

4'-ethyl-1',4',7',8'-tetrahydro-4'-hydroxy-3'H,10'H-spiro[1,3-dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'-dione

indole-2,3-dione
91-56-5

indole-2,3-dione

7-carboxylic acid 20(R,S)-camptothecin

7-carboxylic acid 20(R,S)-camptothecin

Conditions
ConditionsYield
With hydrogenchloride; acetic acid at 105℃; for 15h;100%
N-Ethylmethylamine
624-78-2

N-Ethylmethylamine

indole-2,3-dione
91-56-5

indole-2,3-dione

(2-Amino-phenyl)-oxo-acetic acid; compound with ethyl-methyl-amine

(2-Amino-phenyl)-oxo-acetic acid; compound with ethyl-methyl-amine

Conditions
ConditionsYield
In water Heating;100%
indole-2,3-dione
91-56-5

indole-2,3-dione

di-n-propylamine
142-84-7

di-n-propylamine

(2-Amino-phenyl)-oxo-acetic acid; compound with dipropyl-amine

(2-Amino-phenyl)-oxo-acetic acid; compound with dipropyl-amine

Conditions
ConditionsYield
In water Heating;100%
indole-2,3-dione
91-56-5

indole-2,3-dione

diethylamine
109-89-7

diethylamine

(2-Amino-phenyl)-oxo-acetic acid; compound with diethyl-amine

(2-Amino-phenyl)-oxo-acetic acid; compound with diethyl-amine

Conditions
ConditionsYield
In water Heating;100%
indole-2,3-dione
91-56-5

indole-2,3-dione

diisopropylamine
108-18-9

diisopropylamine

(2-Amino-phenyl)-oxo-acetic acid; compound with diisopropyl-amine

(2-Amino-phenyl)-oxo-acetic acid; compound with diisopropyl-amine

Conditions
ConditionsYield
In water Heating;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

indole-2,3-dione
91-56-5

indole-2,3-dione

1-tert-butoxycarbonylisatin
160858-75-3

1-tert-butoxycarbonylisatin

Conditions
ConditionsYield
With dmap Inert atmosphere;100%
With dmap In tetrahydrofuran at 20℃; for 5h;100%
With dmap In tetrahydrofuran at 20℃; for 6h; Inert atmosphere;96%
indole-2,3-dione
91-56-5

indole-2,3-dione

acetone
67-64-1

acetone

A

(R)-3-hydroxy-3-(2'-oxopropyl)indolin-2-one

(R)-3-hydroxy-3-(2'-oxopropyl)indolin-2-one

B

(S)-3-(2-oxopropyl)-3-hydroxyindolin-2-one

(S)-3-(2-oxopropyl)-3-hydroxyindolin-2-one

Conditions
ConditionsYield
With D-Pro-L-β3-hPhg-OBn; water at -15℃; for 16h; optical yield given as %ee;A 100%
B n/a
With Na(1+)-Montmorillonite-entrapped N-(2-thiophenesulfonyl)-L-prolinamide; trifluoroacetic acid In water at 20℃; for 40h; optical yield given as %ee;A 99%
B n/a
With 1,1′-binaphthyl-2,2′-diamine-L-prolinamide In neat (no solvent) at 25℃; for 24h; Solvent; Temperature; Reagent/catalyst; stereoselective reaction;A n/a
B 98%
N-methoxylamine hydrochloride
593-56-6

N-methoxylamine hydrochloride

indole-2,3-dione
91-56-5

indole-2,3-dione

1H-indole-2,3-dione 3-(O-methyloxime)
107976-78-3

1H-indole-2,3-dione 3-(O-methyloxime)

Conditions
ConditionsYield
With dipotassium hydrogenphosphate In methanol at 20℃; for 2h;100%
With sodium hydrogencarbonate In methanol; water at 50℃; for 8h;92%
With sodium hydrogencarbonate In methanol; water at 20℃; for 1.08333h;80%
2-(bromomethyl)-5-(trifluoromethyl)furan
17515-77-4

2-(bromomethyl)-5-(trifluoromethyl)furan

indole-2,3-dione
91-56-5

indole-2,3-dione

1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1H-indole-2,3-dione
1019767-70-4

1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1H-indole-2,3-dione

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: 2-(bromomethyl)-5-(trifluoromethyl)furan In N,N-dimethyl-formamide at 20℃;
100%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h; Concentration; Reagent/catalyst; Solvent; Temperature; Time; Inert atmosphere;100%
With potassium carbonate In dimethyl sulfoxide at 20 - 30℃;96.4%
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h;
Stage #2: 2-(bromomethyl)-5-(trifluoromethyl)furan In N,N-dimethyl-formamide at 20℃; for 1h;
32%
Stage #1: indole-2,3-dione With potassium carbonate In N,N-dimethyl-formamide at 45℃; for 0.416667h; Inert atmosphere; Large scale;
Stage #2: 2-(bromomethyl)-5-(trifluoromethyl)furan In N,N-dimethyl-formamide at 45 - 54℃; for 2h; Inert atmosphere; Large scale;
Sesamol
533-31-3

Sesamol

indole-2,3-dione
91-56-5

indole-2,3-dione

3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1,3-dihydro-2H-indol-2-one
1019771-89-1

3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
Stage #1: Sesamol With isopropylmagnesium chloride In tetrahydrofuran at 0 - 4℃; for 2h; Industry scale;
Stage #2: indole-2,3-dione In tetrahydrofuran at -5 - 3℃; Industry scale;
Stage #3: With water; ammonium chloride In tetrahydrofuran at 3 - 4℃; Industry scale;
100%
Stage #1: Sesamol With isopropylmagnesium chloride In tetrahydrofuran at 0 - 5℃; for 2.5h;
Stage #2: indole-2,3-dione In tetrahydrofuran at 0 - 20℃; for 19h;
98%
With potassium carbonate In tetrahydrofuran for 17h; Solvent; Inert atmosphere;
With triethylamine In tert-butyl methyl ether at 25℃; for 15h; Inert atmosphere;
In water at 20℃;
1-bromo-2-cyclohexylethane
1647-26-3

1-bromo-2-cyclohexylethane

indole-2,3-dione
91-56-5

indole-2,3-dione

1-(2-cyclohexylethyl)-isatin
1048973-34-7

1-(2-cyclohexylethyl)-isatin

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: 1-bromo-2-cyclohexylethane In N,N-dimethyl-formamide at 20℃;
100%
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: 1-bromo-2-cyclohexylethane In N,N-dimethyl-formamide at 20℃;
100%
indole-2,3-dione
91-56-5

indole-2,3-dione

phosphonic acid diethyl ester
762-04-9

phosphonic acid diethyl ester

malononitrile
109-77-3

malononitrile

diethyl (3-(dicyanomethyl)-2-oxoindolin-3-yl)phosphonate
1210948-52-9

diethyl (3-(dicyanomethyl)-2-oxoindolin-3-yl)phosphonate

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 0.283333h; Reagent/catalyst; Time; Solvent; Ionic liquid; Large scale;100%
With ZnO nano-rods at 20℃; for 1h; Neat (no solvent);98%
at 50℃; for 2h; neat (no solvent);81%
indole-2,3-dione
91-56-5

indole-2,3-dione

ethyl 2-amino-2-hydrazonoacetate

ethyl 2-amino-2-hydrazonoacetate

C12H10N4O2
1394237-93-4

C12H10N4O2

Conditions
ConditionsYield
Stage #1: indole-2,3-dione; ethyl 2-amino-2-hydrazonoacetate In ethanol at 20℃; Reflux; Inert atmosphere;
Stage #2: In bromobenzene for 24h; Inert atmosphere; Reflux;
100%
5-(1',2',3',4'-tetrahydroxybutyl)-2-methylfuran-3-carbohydrazide

5-(1',2',3',4'-tetrahydroxybutyl)-2-methylfuran-3-carbohydrazide

indole-2,3-dione
91-56-5

indole-2,3-dione

5-(1',2',3',4'-tetrahydroxybutyl)-2-methyl-N-(2-oxoindolin-3-ylidene)furan-3-carbohydrazide

5-(1',2',3',4'-tetrahydroxybutyl)-2-methyl-N-(2-oxoindolin-3-ylidene)furan-3-carbohydrazide

Conditions
ConditionsYield
With acetic acid In ethanol for 1h; Reflux;100%
3-amino-2-methyl-4-oxoquinazoline
1898-06-2

3-amino-2-methyl-4-oxoquinazoline

indole-2,3-dione
91-56-5

indole-2,3-dione

indolo[3',2':3,4]pyridazino[6,1-b]quinazolin-7(14H)-one
101507-96-4

indolo[3',2':3,4]pyridazino[6,1-b]quinazolin-7(14H)-one

Conditions
ConditionsYield
With 2,3,4,5,6-pentafluorophenol at 80℃; for 2h;100%
Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

indole-2,3-dione
91-56-5

indole-2,3-dione

methyl 4-((2,3-dioxoindolin-1-yl)methyl)benzoate
380567-18-0

methyl 4-((2,3-dioxoindolin-1-yl)methyl)benzoate

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.0833333h;
Stage #2: Methyl 4-(bromomethyl)benzoate In N,N-dimethyl-formamide; mineral oil at 25℃; for 12h;
100%
With sodium hydride In N,N-dimethyl-formamide at 0℃; for 48.0833h;52%
Stage #1: indole-2,3-dione With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h;
Stage #2: Methyl 4-(bromomethyl)benzoate In N,N-dimethyl-formamide; mineral oil
Stage #1: indole-2,3-dione With potassium carbonate In N,N-dimethyl-formamide for 0.75h;
Stage #2: Methyl 4-(bromomethyl)benzoate With potassium iodide In N,N-dimethyl-formamide at 80℃;
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide
indole-2,3-dione
91-56-5

indole-2,3-dione

1-bromomethyl-2-[(phenylsulfonyl)methyl]benzene
88116-02-3

1-bromomethyl-2-[(phenylsulfonyl)methyl]benzene

(1-(2-benzenesulfonylmethyl-benzyl)-1H‑indole-2,3-dione)

(1-(2-benzenesulfonylmethyl-benzyl)-1H‑indole-2,3-dione)

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With potassium carbonate In N,N-dimethyl-formamide at 0℃; for 0.333333h;
Stage #2: 1-bromomethyl-2-[(phenylsulfonyl)methyl]benzene In N,N-dimethyl-formamide at 20℃; for 3h;
100%
indole-2,3-dione
91-56-5

indole-2,3-dione

7-bromoisatin
20780-74-9

7-bromoisatin

Conditions
ConditionsYield
With N-Bromosuccinimide at 20℃; for 24h;100%
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