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Dayang Chem (Hangzhou) Co.,Ltd.

img _fcksaAppearance:Off-white crystal Storage:Store in dry, dark and ventilated place. Package:according to the clients requirement Application:It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemic

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Indole-2-Carboxylic Acid supplier in China

Cas:1477-50-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 1477-50-5 Indole-2-carboxylic acid Manufacturer

Cas:1477-50-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceuti

1H-Indole-2-carboxylic acid, 4,6-difluoro-, ethyl ester CAS:1477-50-5

Cas:1477-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Indolecarboxylic acid

Cas:1477-50-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--1477-50-5--Indole-2-carboxylic acid in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business re

TIANFUCHEM--1477-50-5--Indole-2-carboxylic acid in stock

Cas:1477-50-5

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name Indole-2-carboxylic acid CAS No. 1477-50-5

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Indole-2-carboxylic acid)

Cas:1477-50-5

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 1477-50-5 with best quality

Cas:1477-50-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 2-Indolecarboxylic acid CAS:1477-50-5 MF: C9H7NO2 Appearance: white crystalline powder Storage:Store in cool and dry place, away from sun light. Package:25kg Application:perindopril intermediate Transportation:By sea or by air Port:Qingdao P

2-Indolecarboxylic acid

Cas:1477-50-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

High Quality 99% Indole-2-carboxylic acid CAS No 1477-50-5

Cas:1477-50-5

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:White powder Storage:storage in a dr

Hotsale Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Indole-2-carboxylic acid CAS:1477-50-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

Indole-2-carboxylic acid CAS:1477-50-5

Cas:1477-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Indole-2-carboxylic acid/ LIDE PHARMA- Factory supply / Best price

Cas:1477-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Biggest Manufacturer factory sales Indole-2-carboxylic acid CAS 1477-50-5

Cas:1477-50-5

Min.Order:1000 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

Indole-2-carboxylic acid-Low Price High Quality CAS NO.1477-50-5

Cas:1477-50-5

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Indole-2-Carboxylic Acid

Cas:1477-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:Yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture.Organic Chemistry Transportation

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1H-Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1H-indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

advantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging

Supply high quality 1477-50-5 Indole-2-carboxylic acid in China

Cas:1477-50-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Wuhan Xinhao Biotechnology Co., Ltd.

1. We can provide customers with "one-stop"packaging service,from research,development,production,export and so on 2. Powerful R&D strength let our technology in a leading level,forever,in turn,to provide customers with better service .

High quality Indole-2-Carboxylic Acid supplier in China

Cas:1477-50-5

Min.Order:100 Gram

FOB Price: $10.0 / 100.0

Type:Trading Company

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Indole-2-Carboxylic Acid

Cas:1477-50-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery Appearance:Off-white crystal powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum;200kg/drum as per your request Application:? ;Reactant for total synthesis of (±)-d

Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply Indole-2-carboxylic acid

Cas:1477-50-5

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

2-carbethoxyindole
3770-50-1

2-carbethoxyindole

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide In water at 120℃; for 0.5h;99.9%
With sodium hydroxide In ethanol; water at 70℃; for 2h;97%
With sodium hydroxide at 200℃; for 0.0166667h; Irradiation; microwave;94%
1-(phenylsulfonyl)-1H-indole-2-carboxylic acid
40899-93-2

1-(phenylsulfonyl)-1H-indole-2-carboxylic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With sodium t-butanolate In 1,4-dioxane at 80℃; for 3h; Inert atmosphere;98%
o-nitrophenylpyruvic acid
5461-32-5

o-nitrophenylpyruvic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With sodium dithionite In 1,4-dioxane; water for 3h; Reflux;96%
With sodium hydroxide; sodium dithionite
indolin-2-yl carboxylic acid
16851-56-2

indolin-2-yl carboxylic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium tert-butylate In decane at 150℃; for 36h; Inert atmosphere; Schlenk technique;96%
With carbon dioxide; DBN; Eosin Y In dimethyl sulfoxide at 25 - 30℃; for 48h; Irradiation;91%
With 4-tert-Butylcatechol; oxygen In water at 20℃; for 20h; Green chemistry;80%
With perylene diimide covalent immobilized to SiO2 nanospheres; air In N,N-dimethyl acetamide at 20℃; UV-irradiation;67%
With oxygen at 80℃; under 760.051 Torr; for 6h; Catalytic behavior; Green chemistry; chemoselective reaction;
(4Z)-4-[(2-bromophenyl)methylene]-2-phenyl-1,3-oxazole-5-one

(4Z)-4-[(2-bromophenyl)methylene]-2-phenyl-1,3-oxazole-5-one

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With methanol; potassium carbonate; copper(I) bromide In N,N-dimethyl-formamide at 20 - 120℃; Reagent/catalyst; Temperature; Solvent;95%
(Z)-2-phenyl-4-(2-chlorobenzylidene)-(4H)-1,3-oxazol-5-one
52900-69-3, 77435-90-6, 82301-55-1

(Z)-2-phenyl-4-(2-chlorobenzylidene)-(4H)-1,3-oxazol-5-one

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With methanol; copper; sodium carbonate In toluene at 20 - 120℃;90%
2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

2-bromoaniline
615-36-1

2-bromoaniline

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium phosphate; bis(N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)palladium(0) In 1,4-dioxane at 100℃; for 10h; Inert atmosphere;89%
carbon dioxide
124-38-9

carbon dioxide

2-bromo-1H-indole
139409-34-0

2-bromo-1H-indole

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 2-bromo-1H-indole With isopropylmagnesium chloride In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: With n-butyllithium In tetrahydrofuran; hexane at -20℃; for 0.5h;
Stage #3: carbon dioxide In tetrahydrofuran; hexane at -20℃; for 0.5h;
85%
n-butyl 1-(pyrimidin-2-yl)-1H-indole-2-carboxylate

n-butyl 1-(pyrimidin-2-yl)-1H-indole-2-carboxylate

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With sodium ethanolate In ethanol; dimethyl sulfoxide at 100℃; for 11h; regioselective reaction;84%
2-iodophenylamine
615-43-0

2-iodophenylamine

2-oxo-propionic acid
127-17-3

2-oxo-propionic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate In N,N-dimethyl-formamide at 105℃;82%
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate In N,N-dimethyl-formamide at 105℃; Inert atmosphere; regioselective reaction;82%
1H-indol-2-ylcarboxaldehyde
19005-93-7

1H-indol-2-ylcarboxaldehyde

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With oxygen; acetic anhydride; CoCl2 In 1,2-dichloro-ethane at 25℃;77%
ethyl 2-nitrophenylpyruvate keto tautomer
784-98-5

ethyl 2-nitrophenylpyruvate keto tautomer

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In water at 70℃; under 3000.3 Torr; for 8h; Temperature; Pressure;70%
Multi-step reaction with 2 steps
1: platinum; acetic acid / Hydrogenation
2: aqueous NaOH
View Scheme
With hydrogen at 50 - 60℃; under 9750.98 - 10501.1 Torr; Autoclave;
2-iodo-1H-indole
26340-49-8

2-iodo-1H-indole

carbon dioxide
124-38-9

carbon dioxide

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 2-iodo-1H-indole With n-butyllithium In tetrahydrofuran
Stage #2: carbon dioxide In tetrahydrofuran
61%
2-carbethoxyindole
3770-50-1

2-carbethoxyindole

1-Bromopentane
110-53-2

1-Bromopentane

A

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

B

ethyl 1-pentyl-1H-indole-2-carboxylate

ethyl 1-pentyl-1H-indole-2-carboxylate

Conditions
ConditionsYield
Stage #1: 2-carbethoxyindole With potassium hydroxide In water; acetone at 20℃; for 0.5h;
Stage #2: 1-Bromopentane In water; acetone at 20℃; for 8h;
A 30%
B 60%
6H,13H-pyrazino<1,2-a:4,5-a'>diindole-6,13-dione
58881-41-7

6H,13H-pyrazino<1,2-a:4,5-a'>diindole-6,13-dione

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With lithium hydroxide In tetrahydrofuran at 20℃; for 2h;57%
3-(2-nitrophenyl)-2-oxopropanoic sodium salt

3-(2-nitrophenyl)-2-oxopropanoic sodium salt

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With ammonium hydroxide; hydrogen In methanol pH=7.5;56%
2-carbethoxyindole
3770-50-1

2-carbethoxyindole

A

indole
120-72-9

indole

B

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With sodium acetate In water at 255℃; for 0.333333h; Product distribution; Irradiation; microwave; various equivalents and molarity of NaOAc; effect of temp., and time;A 45%
B 55%
(tert-Butoxycarbonylmethylene)triphenylphosphorane
86302-43-4

(tert-Butoxycarbonylmethylene)triphenylphosphorane

2-nitro-benzaldehyde
552-89-6

2-nitro-benzaldehyde

A

indole
120-72-9

indole

B

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With 1,2-dichloro-benzene; triphenylphosphine for 15h; Reflux;A 29%
B 27%
indole
120-72-9

indole

A

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

B

1H-indole-3-carboxylic acid
771-50-6

1H-indole-3-carboxylic acid

Conditions
ConditionsYield
With sodium at 230 - 250℃; im Kohlendioxyd-Strom; zuletzt bei 300grad;
2-methyl-1H-indole
95-20-5

2-methyl-1H-indole

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide beim Schmelzen;
1-acetyl-2-methylindole
37842-85-6

1-acetyl-2-methylindole

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide beim Schmelzen;
1,2,3,4-tetrahydrocarbazole
942-01-8

1,2,3,4-tetrahydrocarbazole

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide beim Schmelzen;
1-hydroxy-1H-indole-2-carboxylic acid
16264-71-4

1-hydroxy-1H-indole-2-carboxylic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With acetic acid; zinc
With sodium amalgam
1-acetyl-3-hydroxy-indoline-2-carboxylic acid ethyl ester
105911-78-2

1-acetyl-3-hydroxy-indoline-2-carboxylic acid ethyl ester

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide
ethyl 2-(3-N,N-diethylaminomethylindole)carboxylate
91486-86-1

ethyl 2-(3-N,N-diethylaminomethylindole)carboxylate

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With barium dihydroxide
(2-nitro-phenyl)-glyoxylic acid
610-33-3

(2-nitro-phenyl)-glyoxylic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
With acetic acid; zinc
With ammonia; iron(II) sulfate
2-amino-α-methoxy-cinnamic acid

2-amino-α-methoxy-cinnamic acid

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
beim Erhitzen ueber den Schmelzpunkt;
With sulfuric acid
With hydrogenchloride
beim Erhitzen ueber den Schmelzpunkt;
1-(2-indol-2-yl-2-oxo-ethyl)-pyridinium; bromide

1-(2-indol-2-yl-2-oxo-ethyl)-pyridinium; bromide

benzaldehyde
100-52-7

benzaldehyde

A

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

B

1-(2-hydroxy-2-phenylethyl)pyridinium bromide
6318-99-6

1-(2-hydroxy-2-phenylethyl)pyridinium bromide

Conditions
ConditionsYield
With sodium hydroxide
(E)-3-Ureido-but-2-enoic acid ethyl ester
5435-44-9, 22243-66-9

(E)-3-Ureido-but-2-enoic acid ethyl ester

ethyl pyruvate phenylhydrazone
4792-54-5

ethyl pyruvate phenylhydrazone

A

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

B

2-carbethoxyindole
3770-50-1

2-carbethoxyindole

Conditions
ConditionsYield
at 195℃; α-form;
Yohimbine
146-48-5

Yohimbine

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Conditions
ConditionsYield
at 240 - 280℃; bei der Kalischmelze;neben anderen Produkten;
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

indole-2-carboxylic acid methyl ester
1202-04-6

indole-2-carboxylic acid methyl ester

Conditions
ConditionsYield
In diethyl ether100%
With acetic acid In diethyl ether at -20℃;100%
In diethyl ether at 0℃;97%
With diethyl ether
methanol
67-56-1

methanol

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

indole-2-carboxylic acid methyl ester
1202-04-6

indole-2-carboxylic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride for 24h; Heating;100%
Stage #1: methanol; Indole-2-carboxylic acid With sulfuric acid for 12h; Heating / reflux;
Stage #2: In methanol; water pH=7;
100%
With sulfuric acid for 24h; Reflux;99%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

ethanol
64-17-5

ethanol

2-carbethoxyindole
3770-50-1

2-carbethoxyindole

Conditions
ConditionsYield
With hydrogenchloride for 24h; Heating / reflux;100%
With thionyl chloride In methanol at 0℃; Reflux;99%
With thionyl chloride for 2.25h; Cooling with ice; Reflux;99%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

sec-Butyl-(2-piperazin-1-yl-pyridin-3-yl)-amine

sec-Butyl-(2-piperazin-1-yl-pyridin-3-yl)-amine

1-(indolyl-2-carbonyl)-4-<3-<(1-methylpropyl)amino>-2-pyridyl>piperazine

1-(indolyl-2-carbonyl)-4-<3-<(1-methylpropyl)amino>-2-pyridyl>piperazine

Conditions
ConditionsYield
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In tetrahydrofuran for 4h; Ambient temperature;100%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

4-[(tert-butoxy)carbonyl]-1-[(4-methoxyphenyl)methyl]-6-(phenylmethyl)piperazin-2-one
305324-48-5

4-[(tert-butoxy)carbonyl]-1-[(4-methoxyphenyl)methyl]-6-(phenylmethyl)piperazin-2-one

16F7

16F7

Conditions
ConditionsYield
Stage #1: 4-[(tert-butoxy)carbonyl]-1-[(4-methoxyphenyl)methyl]-6-(phenylmethyl)piperazin-2-one With hydrogenchloride In ethyl acetate deprotection;
Stage #2: Indole-2-carboxylic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine Acylation;
100%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

3-Phenyl-2-propyn-1-ol
1504-58-1

3-Phenyl-2-propyn-1-ol

3-phenylprop-2-yn-1-yl 1H-indole-2-carboxylate

3-phenylprop-2-yn-1-yl 1H-indole-2-carboxylate

Conditions
ConditionsYield
Stage #1: Indole-2-carboxylic acid With dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 0.166667h;
Stage #2: 3-Phenyl-2-propyn-1-ol With dmap In dichloromethane at 0℃; for 2h;
100%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

methyl 4-(1-(N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamido)cyclopropyl)benzoate dihydrochloride

methyl 4-(1-(N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamido)cyclopropyl)benzoate dihydrochloride

methyl 4-(1-(5-(1H-indole-2-carbonyl)-N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamido)cyclopropyl)benzoate

methyl 4-(1-(5-(1H-indole-2-carbonyl)-N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamido)cyclopropyl)benzoate

Conditions
ConditionsYield
Stage #1: Indole-2-carboxylic acid With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide for 0.25h;
Stage #2: methyl 4-(1-(N-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-3-carboxamido)cyclopropyl)benzoate dihydrochloride In N,N-dimethyl-formamide for 1h;
100%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

methyl iodide
74-88-4

methyl iodide

methyl 1-methyl-1H-indole-2-carboxylate
37493-34-8

methyl 1-methyl-1H-indole-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; Inert atmosphere;99%
Stage #1: Indole-2-carboxylic acid With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Metallation;
Stage #2: methyl iodide In N,N-dimethyl-formamide at 20℃; for 5h; Alkylation;
72.4%
In N-methyl-acetamide1.70 g (72.4%)
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

benzylamine
100-46-9

benzylamine

N-benzyl-1H-indole-2-carboxamide
69808-76-0

N-benzyl-1H-indole-2-carboxamide

Conditions
ConditionsYield
With Bromotrichloromethane; 4-(diphenylphosphino)-benzyltrimethylammonium bromide; triethylamine In tetrahydrofuran; dichloromethane at 60℃; for 6h; Inert atmosphere;99%
Stage #1: Indole-2-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: benzylamine In tetrahydrofuran at 20℃; for 24h;
95%
With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V) In N,N-dimethyl-formamide at 20℃;74%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 25℃; for 4h;70%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

iodobenzene
591-50-4

iodobenzene

1-phenyl-1H-indole
16096-33-6

1-phenyl-1H-indole

Conditions
ConditionsYield
With copper(I) oxide; potassium phosphate In 1-methyl-pyrrolidin-2-one at 160℃; for 12h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Schlenk technique;99%
tert-butyl (3S)-3-(methylamino)pyrrolidine-1-carboxylate
147081-59-2

tert-butyl (3S)-3-(methylamino)pyrrolidine-1-carboxylate

Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

tert-butyl (3S)-3-[1H-indole-2-carbonyl(methyl)amino]pyrrolidine-1-carboxylate

tert-butyl (3S)-3-[1H-indole-2-carbonyl(methyl)amino]pyrrolidine-1-carboxylate

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 20℃; for 12h;99%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

N-methoxy-N-methyl-1H-indole-2-carboxamide
156571-69-6

N-methoxy-N-methyl-1H-indole-2-carboxamide

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 12h;98.3%
Stage #1: Indole-2-carboxylic acid; N,O-dimethylhydroxylamine*hydrochloride With triethylamine In dichloromethane for 0.0833333h;
Stage #2: With dicyclohexyl-carbodiimide In dichloromethane for 3h;
96%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0 - 20℃; for 4h;87%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

Indole-2-carbonyl chloride
58881-45-1

Indole-2-carbonyl chloride

Conditions
ConditionsYield
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 40℃; for 1.5h;98%
With thionyl chloride In diethyl ether at 20℃; for 12h;96%
With thionyl chloride In dichloromethane at 70℃; for 2h;95%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

ethyl β-alaninate hydrochloride
4244-84-2

ethyl β-alaninate hydrochloride

3-[(1H-indole-2-carbonyl)amino]propionic acid ethyl ester
68724-78-7

3-[(1H-indole-2-carbonyl)amino]propionic acid ethyl ester

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 24h;98%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 24h; Condensation;95%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 24h; Inert atmosphere;90%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

N-methyl-1-naphthalenemethylamine hydrochloride
65473-13-4

N-methyl-1-naphthalenemethylamine hydrochloride

1H-indole-2-carboxylic acid methyl-naphthalen-1-ylmethyl-amide

1H-indole-2-carboxylic acid methyl-naphthalen-1-ylmethyl-amide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 4.5h; Condensation;98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

4-Aminobutanol
13325-10-5

4-Aminobutanol

N-(4-hydroxybutyl)-1H-indole-2-carboxamide
600709-74-8

N-(4-hydroxybutyl)-1H-indole-2-carboxamide

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In tetrahydrofuran; N,N-dimethyl-formamide at 20℃;98%
Stage #1: Indole-2-carboxylic acid With 1-hydroxybenzotriazol-hydrate; dicyclohexyl-carbodiimide In dichloromethane at 20℃;
Stage #2: 4-Aminobutanol In dichloromethane at 20℃;
93%
Stage #1: Indole-2-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; Inert atmosphere;
Stage #2: 4-Aminobutanol In dichloromethane at 20℃; for 16h; Inert atmosphere;
93%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

3-amino-propionic acid ethyl ester
924-73-2

3-amino-propionic acid ethyl ester

3-[(1H-indole-2-carbonyl)amino]propionic acid ethyl ester
68724-78-7

3-[(1H-indole-2-carbonyl)amino]propionic acid ethyl ester

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane98%
With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide at 20℃;
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

1-phenylmethylpiperazine
2759-28-6

1-phenylmethylpiperazine

2-(4-benzylpiperazin-1-yl)carbonyl indole hydrochloride

2-(4-benzylpiperazin-1-yl)carbonyl indole hydrochloride

Conditions
ConditionsYield
With thionyl chloride In toluene98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

N-[(4-methoxyphenyl)methyl]prop-2-yn-1-amine
98729-72-7

N-[(4-methoxyphenyl)methyl]prop-2-yn-1-amine

N-(4-methoxybenzyl)-N-propargyl-1H-indole-2-carboxamide
1250829-42-5

N-(4-methoxybenzyl)-N-propargyl-1H-indole-2-carboxamide

Conditions
ConditionsYield
Stage #1: Indole-2-carboxylic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 20℃; for 2h; Reflux;
Stage #2: N-(4-methoxybenzyl)prop-2-yn-1-amine With triethylamine In dichloromethane at 0 - 20℃; for 1h;
98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

N-(4-methylbenzyl)prop-2-yn-1-amine
892594-94-4

N-(4-methylbenzyl)prop-2-yn-1-amine

N-(4-methylbenzyl)-N-propargyl-1H-indole-2-carboxamide
1250829-43-6

N-(4-methylbenzyl)-N-propargyl-1H-indole-2-carboxamide

Conditions
ConditionsYield
Stage #1: Indole-2-carboxylic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 20℃; for 2h; Reflux;
Stage #2: N-(4-methylbenzyl)prop-2-yn-1-amine With triethylamine In dichloromethane at 0 - 20℃; for 1h;
98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

2,2-dimethoxyethylamine
22483-09-6

2,2-dimethoxyethylamine

N-(2,2-dimethoxyethyl)-1H-indole-2-carboxamide

N-(2,2-dimethoxyethyl)-1H-indole-2-carboxamide

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 25℃; for 2h;98%
With 1,1'-carbonyldiimidazole In 1,4-dioxane at 70℃; for 3h;
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

3,3-dichloro-2,3-dihydro-1H-indol-2-one
39033-45-9

3,3-dichloro-2,3-dihydro-1H-indol-2-one

Conditions
ConditionsYield
With 1,3-dichloro-5,5-dimethylhydantoin In ethyl acetate at 20℃;98%
Multi-step reaction with 2 steps
1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / 20 °C
2: 1,3-dichloro-5,5-dimethylhydantoin / ethyl acetate / 20 °C
View Scheme
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride
5680-80-8

methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

methyl (1H-indole-2-carbonyl)-L-serinate

methyl (1H-indole-2-carbonyl)-L-serinate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0 - 20℃; for 18h;98%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 0 - 20℃; for 24h;98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

para-nitrophenyl bromide
586-78-7

para-nitrophenyl bromide

1-(4-nitrophenyl)-1H-indole-2-carboxylic acid
65439-85-2

1-(4-nitrophenyl)-1H-indole-2-carboxylic acid

Conditions
ConditionsYield
With quebrachitol; copper; caesium carbonate In water; dimethyl sulfoxide at 100℃; Ullmann Condensation; Inert atmosphere; Green chemistry;98%
With copper; caesium carbonate; methyl-alpha-D-glucopyranoside In water; dimethyl sulfoxide at 100℃; Sealed tube; Green chemistry;91%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

m-bromobenzoic acid
585-76-2

m-bromobenzoic acid

1-(3-carboxyphenyl)-1H-indole-2-carboxylic acid

1-(3-carboxyphenyl)-1H-indole-2-carboxylic acid

Conditions
ConditionsYield
With quebrachitol; copper; caesium carbonate In water; dimethyl sulfoxide at 100℃; Ullmann Condensation; Inert atmosphere; Green chemistry;98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

indole-2,3-dione
91-56-5

indole-2,3-dione

Conditions
ConditionsYield
With oxygen; Rose Bengal lactone In water; N,N-dimethyl-formamide for 48h; Inert atmosphere; Irradiation;98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

(S)-serine methyl ester
2788-84-3

(S)-serine methyl ester

methyl (1H-indole-2-carbonyl)-L-serinate

methyl (1H-indole-2-carbonyl)-L-serinate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane for 18h;98%
Indole-2-carboxylic acid
1477-50-5

Indole-2-carboxylic acid

(E)-methyl 2-((methylamino)methyl)-3-phenylacrylate
1021167-64-5

(E)-methyl 2-((methylamino)methyl)-3-phenylacrylate

C21H20N2O3

C21H20N2O3

Conditions
ConditionsYield
Stage #1: Indole-2-carboxylic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dimethyl sulfoxide at 20℃; for 0.416667h; Michael Addition; Inert atmosphere; Schlenk technique;
Stage #2: (E)-methyl-2-((methylamino)methyl)-3-phenylacrylate With triethylamine In dimethyl sulfoxide at 20℃; for 3h; Michael Addition; Inert atmosphere; Schlenk technique;
98%

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