Product Name

  • Name

    Butanoic acid,1,1'-anhydride

  • EINECS 203-383-4
  • CAS No. 106-31-0
  • Article Data80
  • CAS DataBase
  • Density 0.981 g/cm3
  • Solubility decomposes in water
  • Melting Point -73 °C
  • Formula C8H14O3
  • Boiling Point 198.279 °C at 760 mmHg
  • Molecular Weight 158.197
  • Flash Point 87.778 °C
  • Transport Information UN 2739 8/PG 3
  • Appearance clear liquid
  • Safety 26-36/37/39-45
  • Risk Codes 14-34
  • Molecular Structure Molecular Structure of 106-31-0 (Butanoic acid,1,1'-anhydride)
  • Hazard Symbols CorrosiveC
  • Synonyms Butanoicacid, anhydride (9CI);Butyric anhydride (6CI,8CI);Butanoic anhydride;Butanoyl anhydride;Butyric acid anhydride;Butyryl oxide;n-Butyric acidanhydride;n-Butyric anhydride;
  • PSA 43.37000
  • LogP 1.65640

Synthetic route

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane at 20℃; for 0.5h;95%
With PEG-1000; sulfated zirconia at 40℃; for 3h; neat (no solvent);85%
at 230℃; under 2574.3 Torr;
4-Ethoxyphenyltellurium oxochloride
40957-08-2

4-Ethoxyphenyltellurium oxochloride

butyryl chloride
141-75-3

butyryl chloride

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

p-ethoxyphenyltellurium(IV) trichloride
36310-31-3

p-ethoxyphenyltellurium(IV) trichloride

Conditions
ConditionsYield
In tetrachloromethane for 1h; Heating; prototype reaction, oth. acylchlorides, oth. arenetellurinyl chloride;A 89%
B 93%
(dibutyrylhydroxy)triphenylarsorane
125911-01-5

(dibutyrylhydroxy)triphenylarsorane

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

triphenyl-arsane
603-32-7

triphenyl-arsane

C

triphenylarsineoxide
1153-05-5, 856568-31-5

triphenylarsineoxide

Conditions
ConditionsYield
Product distribution; Heating;A 76%
B 38%
C 43%
butyric acid
107-92-6

butyric acid

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

butyryl chloride
141-75-3

butyryl chloride

Conditions
ConditionsYield
With phosphorus trichloride at 40 - 50℃; 4-5h;A n/a
B 67%
With phosphorus trichloride at 40 - 50℃; 4-5h;A 10.54%
B 49.3%
butyraldehyde
123-72-8

butyraldehyde

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
With oxygen; cobalt(II) chloride In acetonitrile at 25℃; for 15h;43%
butyraldehyde
123-72-8

butyraldehyde

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

Methyl 2-hydroxy-4-oxoheptanoate

Methyl 2-hydroxy-4-oxoheptanoate

C

Methyl 2-butyryloxy-4-oxoheptanoate

Methyl 2-butyryloxy-4-oxoheptanoate

D

butyric acid
107-92-6

butyric acid

Conditions
ConditionsYield
With acetic anhydride; cobalt(II) In acetonitrile at 25℃; for 24h;A n/a
B 18%
C 20%
D n/a
crotonic anhydride
623-68-7

crotonic anhydride

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
With nickel Hydrogenation;
peroxybutyric acid
13122-71-9

peroxybutyric acid

butyraldehyde
123-72-8

butyraldehyde

ethyl acetate
141-78-6

ethyl acetate

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

butyric acid
107-92-6

butyric acid

Conditions
ConditionsYield
at 20 - 50℃; Rate constant; auch nach Zusatz Kupfer(II)-, Mangan(II)-, Eisen(II)-, Kobalt(II)- und Nickel(II)-butyrat;
butyraldehyde
123-72-8

butyraldehyde

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
With oxygen; copper diacetate; cobalt(II) acetate at 50℃; under 1471.02 Torr;
With oxygen; cobalt(II) carbonate at 50℃; under 1471.02 Torr;
With oxygen; manganese(II) acetate at 50℃; under 1471.02 Torr;
acetyl chloride
75-36-5

acetyl chloride

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
at 120 - 180℃;
silver butyrate
5076-24-4

silver butyrate

butyryl chloride
141-75-3

butyryl chloride

butanoic acid anhydride
106-31-0

butanoic acid anhydride

butyryl chloride
141-75-3

butyryl chloride

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
zeitlicher Verlauf;
With potassium chloride
at 120 - 180℃;
butyryl chloride
141-75-3

butyryl chloride

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
With lead(II) nitrate
acetone
67-64-1

acetone

butyric acid
107-92-6

butyric acid

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

acetic butyric anhydride
7165-13-1

acetic butyric anhydride

Conditions
ConditionsYield
With copper at 635℃;
1-ethoxyacetylene
927-80-0

1-ethoxyacetylene

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

prop-1-yne
74-99-7

prop-1-yne

butyric acid
107-92-6

butyric acid

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

acetone
67-64-1

acetone

Conditions
ConditionsYield
With sulfuric acid; mercury(II) oxide at 60 - 65℃;
Ketene
463-51-4

Ketene

butyric acid
107-92-6

butyric acid

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

acetic anhydride
108-24-7

acetic anhydride

Conditions
ConditionsYield
anschliessendes Erhitzen der Reaktionsprodukte;
anschliessendes Erhitzen der Reaktionsprodukte;
oxalyl dichloride
79-37-8

oxalyl dichloride

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

Conditions
ConditionsYield
With benzene
ethynyl methyl ether
6443-91-0

ethynyl methyl ether

butyric acid
107-92-6

butyric acid

butanoic acid anhydride
106-31-0

butanoic acid anhydride

ethynyl methyl ether
6443-91-0

ethynyl methyl ether

butyric acid
107-92-6

butyric acid

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

acetic acid methyl ester
79-20-9

acetic acid methyl ester

Conditions
ConditionsYield
analoge Reaktionen mit weiteren Saeuren;
vinyl n-butyrate
123-20-6

vinyl n-butyrate

butyric acid
107-92-6

butyric acid

A

butanoic acid anhydride
106-31-0

butanoic acid anhydride

B

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
With sulfuric acid
With sulfur dichloride
butanoic acid anhydride
106-31-0

butanoic acid anhydride

methyl (2RS,3RS)-2-hydroxy-3-(p-methoxyphenyl)-3-(o-nitrophenylthio)propanoate
30067-00-6, 84056-03-1, 86603-47-6, 125354-93-0, 125354-94-1, 127419-59-4, 131064-04-5, 142926-03-2

methyl (2RS,3RS)-2-hydroxy-3-(p-methoxyphenyl)-3-(o-nitrophenylthio)propanoate

Butyric acid (1R,2R)-1-methoxycarbonyl-2-(4-methoxy-phenyl)-2-(2-nitro-phenylsulfanyl)-ethyl ester

Butyric acid (1R,2R)-1-methoxycarbonyl-2-(4-methoxy-phenyl)-2-(2-nitro-phenylsulfanyl)-ethyl ester

Conditions
ConditionsYield
With dmap In tetrahydrofuran at 22℃; for 48h; lipase from Pseudomonas cepacia;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

10-butyryl-10-desacetylbaccatin III

10-butyryl-10-desacetylbaccatin III

Conditions
ConditionsYield
With cerium(III) chloride In tetrahydrofuran at 25℃; for 3h;100%
With cerium(III) chloride In tetrahydrofuran at 25℃; for 3h;100%
With cerium(III) chloride In tetrahydrofuran at 25℃; for 3h; Under N2;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

1-hydroxy-1,2-dihydrothiazolo[3,2-a]quinolinium perchlorate

1-hydroxy-1,2-dihydrothiazolo[3,2-a]quinolinium perchlorate

1-butyroxy-1,2-dihydrothiazolo[3,2-a]quinolinium perchlorate

1-butyroxy-1,2-dihydrothiazolo[3,2-a]quinolinium perchlorate

Conditions
ConditionsYield
With pyridine at 20℃; for 0.5h; Acetylation;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

3,4-dimethoxy-4-[[[2-(3-methoxyphenyl)ethyl]amino]methyl]phenoxy-Merrifield resin; 3,5-dimethoxy-4-[[[2-(2,5-dimethoxyphenyl)ethyl]amino]methyl]phenoxy-Merrifield resin

3,4-dimethoxy-4-[[[2-(3-methoxyphenyl)ethyl]amino]methyl]phenoxy-Merrifield resin; 3,5-dimethoxy-4-[[[2-(2,5-dimethoxyphenyl)ethyl]amino]methyl]phenoxy-Merrifield resin

N-[2-(3-methoxyphenyl)ethyl]butyramide; N-[2-(2,5-dimethoxyphenyl)ethyl]butyramide; mixture of

N-[2-(3-methoxyphenyl)ethyl]butyramide; N-[2-(2,5-dimethoxyphenyl)ethyl]butyramide; mixture of

Conditions
ConditionsYield
Stage #1: butanoic acid anhydride; 3,4-dimethoxy-4-[[[2-(3-methoxyphenyl)ethyl]amino]methyl]phenoxy-Merrifield resin; 3,5-dimethoxy-4-[[[2-(2,5-dimethoxyphenyl)ethyl]amino]methyl]phenoxy-Merrifield resin With pyridine; dmap at 50℃; for 12h; Solid phase reaction; acylation;
Stage #2: With dimethylsulfide; water; trifluoroacetic acid In dichloromethane at 20℃; for 15h; Solid phase reaction; cleavage of amide;
100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

3-fluoro-4-[5-(4-methoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
606126-05-0

3-fluoro-4-[5-(4-methoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

N1-butyryl-3-fluoro-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide

N1-butyryl-3-fluoro-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 24h;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

3-fluoro-4-[5-(4-fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

3-fluoro-4-[5-(4-fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

N1-butyryl-4-[5-(4-fluorophenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-3-fluoro-1-benzenesulfonamide

N1-butyryl-4-[5-(4-fluorophenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-3-fluoro-1-benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 24h;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

3-fluoro-4-[5-(4-methylsulfanyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
606126-06-1

3-fluoro-4-[5-(4-methylsulfanyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

N1-butyryl-3-fluoro-4-[5-(4-methylsulfanylphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide

N1-butyryl-3-fluoro-4-[5-(4-methylsulfanylphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 24h;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

2-phenylethanol
60-12-8

2-phenylethanol

phenethyl butyrate
103-52-6

phenethyl butyrate

Conditions
ConditionsYield
Stage #1: butanoic acid anhydride With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: 2-phenylethanol In dichloromethane at 20℃; for 0.15h;
100%
With iron(III) p-toluenesulfonate hexahydrate In neat (no solvent) at 20℃; for 1h;85%
phenyl 2-O-benzyl-1-thio-α-L-rhamnopyranoside
849938-16-5

phenyl 2-O-benzyl-1-thio-α-L-rhamnopyranoside

butanoic acid anhydride
106-31-0

butanoic acid anhydride

phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside
910041-16-6

phenyl 3,4-di-O-butyryl-2-O-benzyl-1-thio-α-L-rhamnopyranoside

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 2h;100%
With dmap; triethylamine In dichloromethane at 20℃; for 2h;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

3-(6-fluoro-1H-benzimidazol-2-yl)-D-alanine
884047-64-7

3-(6-fluoro-1H-benzimidazol-2-yl)-D-alanine

C14H16FN3O3
884033-78-7

C14H16FN3O3

Conditions
ConditionsYield
Stage #1: butanoic acid anhydride; 3-(6-fluoro-1H-benzimidazol-2-yl)-D-alanine With sodium carbonate In water; acetonitrile at 25℃; for 15h;
Stage #2: With hydrogenchloride In water; acetonitrile at 0℃; pH=2;
100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

2,4,4'-trihydroxy deoxybenzoin
17720-60-4

2,4,4'-trihydroxy deoxybenzoin

7-hydroxy-3-(4-hydroxy-phenyl)-2-propyl-chromen-4-one
1096623-03-8

7-hydroxy-3-(4-hydroxy-phenyl)-2-propyl-chromen-4-one

Conditions
ConditionsYield
Stage #1: butanoic acid anhydride; 2,4,4'-trihydroxy deoxybenzoin With triethylamine for 22h; Heating / reflux;
Stage #2: With hydrogenchloride In water at 20℃; for 2h; pH=5;
Stage #3: With hydrogenchloride; sodium hydroxide; water more than 3 stages;
100%
(±)-1,2:4,5-di-O-cyclohexylidene-myo-inositol

(±)-1,2:4,5-di-O-cyclohexylidene-myo-inositol

butanoic acid anhydride
106-31-0

butanoic acid anhydride

(±)-1,4-di-O-butyryl-2,3:5,6-di-O-cyclohexylidene-myo-inositol

(±)-1,4-di-O-butyryl-2,3:5,6-di-O-cyclohexylidene-myo-inositol

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane; N,N-dimethyl-formamide at 0 - 25℃; for 16h; Inert atmosphere;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

(R)-N1-hexyl-4-((S)-2-(2-(3-((3-hydroxypropyl)amino)phenoxy)acetamido)propanamido)pentanediamide

(R)-N1-hexyl-4-((S)-2-(2-(3-((3-hydroxypropyl)amino)phenoxy)acetamido)propanamido)pentanediamide

(R)-N1-hexyl-4-((S)-2-(2-(3-(N-(3-hydroxypropyl)butyramido)phenoxy)acetamido)propanamido)pentanediamide

(R)-N1-hexyl-4-((S)-2-(2-(3-(N-(3-hydroxypropyl)butyramido)phenoxy)acetamido)propanamido)pentanediamide

Conditions
ConditionsYield
In methanol at 20℃;100%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

1,3-O-dibenzyl-2-N-butyryl-6-O-(N-Boc-L-valyl)-D-glucosamine

1,3-O-dibenzyl-2-N-butyryl-6-O-(N-Boc-L-valyl)-D-glucosamine

1,3-O-dibenzyl-2-N-4-O-dibutyryl-6-O-(N-Boc-L-valyl)-D-glucosamine

1,3-O-dibenzyl-2-N-4-O-dibutyryl-6-O-(N-Boc-L-valyl)-D-glucosamine

Conditions
ConditionsYield
With pyridine; dmap at 20℃;99.8%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

1-O-benzyl-2-N-butyryl-6-O-(tert-butyldimethylsilyl)-D-glucosamine

1-O-benzyl-2-N-butyryl-6-O-(tert-butyldimethylsilyl)-D-glucosamine

1-O-benzyl-2-N-3,4-O-tributyryl-6-O-(tert-butyldimentylsilyl)-D-glucosamine

1-O-benzyl-2-N-3,4-O-tributyryl-6-O-(tert-butyldimentylsilyl)-D-glucosamine

Conditions
ConditionsYield
With pyridine; dmap at 20 - 50℃;99.8%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

1,3,5-triphenylhexahydro-1,3,5-triazine
91-78-1

1,3,5-triphenylhexahydro-1,3,5-triazine

Butyric acid (butyryl-phenyl-amino)-methyl ester
112780-09-3

Butyric acid (butyryl-phenyl-amino)-methyl ester

Conditions
ConditionsYield
at 140℃; for 1h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

3,4,5,6-tetra-O-benzyl inositol
24558-77-8

3,4,5,6-tetra-O-benzyl inositol

D-3,4,5,6-Tetra-O-benzyl-1,2-di-O-butyryl-myo-inositol
163493-87-6

D-3,4,5,6-Tetra-O-benzyl-1,2-di-O-butyryl-myo-inositol

Conditions
ConditionsYield
With pyridine; dmap for 1h; Ambient temperature;99%
With pyridine at 50℃; for 24h;95%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

2-amino-6-fluoro-9-(4-hydroxy-3-hydroxy-methylbutyl)purine
222842-93-5

2-amino-6-fluoro-9-(4-hydroxy-3-hydroxy-methylbutyl)purine

butyric acid 4-(2-amino-6-fluoro-purin-9-yl)-2-butyryloxymethyl-butyl ester

butyric acid 4-(2-amino-6-fluoro-purin-9-yl)-2-butyryloxymethyl-butyl ester

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide for 0.5h; Ambient temperature;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

(1aR,1bR,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-Tetrahydroxy-1,1,6,8-tetramethyl-2-trityloxymethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-cyclopropa[3,4]benzo[1,2-e]azulen-5-one

(1aR,1bR,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-Tetrahydroxy-1,1,6,8-tetramethyl-2-trityloxymethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-cyclopropa[3,4]benzo[1,2-e]azulen-5-one

20-trityl-phorbol-12,13-dibutyrate

20-trityl-phorbol-12,13-dibutyrate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

2-phenyl-4-(D-erithro-1',2',3'-trihydroxypropyl)-2H-1,2,3-triazole
6631-53-4

2-phenyl-4-(D-erithro-1',2',3'-trihydroxypropyl)-2H-1,2,3-triazole

2-phenyl-4-(D-erithro-3'-butanoyloxy-1',2'-dihydroxypropyl)-2H-1,2,3-triazole

2-phenyl-4-(D-erithro-3'-butanoyloxy-1',2'-dihydroxypropyl)-2H-1,2,3-triazole

Conditions
ConditionsYield
With Candida antarctica lipase B In di-isopropyl ether at 42 - 45℃; for 1h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

2-phenyl-4-(D-arabino-1',2',3',4'-tetrahydroxybutyl)-2H-1,2,3-triazole
6341-06-6

2-phenyl-4-(D-arabino-1',2',3',4'-tetrahydroxybutyl)-2H-1,2,3-triazole

2-phenyl-4-(D-arabino-4'-butanoyloxy-1',2',3'-trihydroxybutyl)-2H-1,2,3-triazole

2-phenyl-4-(D-arabino-4'-butanoyloxy-1',2',3'-trihydroxybutyl)-2H-1,2,3-triazole

Conditions
ConditionsYield
With Candida antarctica lipase B In di-isopropyl ether at 42 - 45℃; for 2.5h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

Lipase OF

Lipase OF

Racemic 1-oxo-5-hydroxymethyl-2-cyclohexene

Racemic 1-oxo-5-hydroxymethyl-2-cyclohexene

1-oxo-5-butyroyloxymethyl-2-cyclohexene

1-oxo-5-butyroyloxymethyl-2-cyclohexene

Conditions
ConditionsYield
In di-isopropyl ether99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

uridine
58-96-8

uridine

2',3',4'-tri-O-butyryluridine

2',3',4'-tri-O-butyryluridine

Conditions
ConditionsYield
With pyridine at 20℃; for 25h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

6-(5,5-dimethyl-1,3-dioxan-2-yl)-6-methyldihydro-2H-pyran-2,4(3H)-dione
1311311-22-4

6-(5,5-dimethyl-1,3-dioxan-2-yl)-6-methyldihydro-2H-pyran-2,4(3H)-dione

3-butyryl-6-(5,5-dimethyl-1,3-dioxan-2-yl)-6-methyldihydro-2H-pyran-2,4(3H)-dione
1311311-23-5

3-butyryl-6-(5,5-dimethyl-1,3-dioxan-2-yl)-6-methyldihydro-2H-pyran-2,4(3H)-dione

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 16.17h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

rac-tert-butyl 2-(1-hydroxy-3-methylbutyl)thiazole-4-carboxylate
1380359-04-5

rac-tert-butyl 2-(1-hydroxy-3-methylbutyl)thiazole-4-carboxylate

rac-tert-butyl 2-(1-(butyryloxy)-3-methylbutyl)thiazole-4-carboxylate
1380359-18-1

rac-tert-butyl 2-(1-(butyryloxy)-3-methylbutyl)thiazole-4-carboxylate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 20℃; for 0.5h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

rac-1-(4-bromothiazol-2-yl)ethanol
1370356-21-0

rac-1-(4-bromothiazol-2-yl)ethanol

rac-1-(4-bromothiazol-2-yl)ethyl butyrate
1380359-21-6

rac-1-(4-bromothiazol-2-yl)ethyl butyrate

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 20℃; for 0.5h;99%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

1,6:3,4-bis-myo-inositol
176798-27-9

1,6:3,4-bis-myo-inositol

1,6:3,4-bis[O-(2,3-dimethoxybutane-2,3-diyl)]-2,5-di-O-butyryl-myo-inositol

1,6:3,4-bis[O-(2,3-dimethoxybutane-2,3-diyl)]-2,5-di-O-butyryl-myo-inositol

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane; N,N-dimethyl-formamide at 0 - 25℃; for 16h; Inert atmosphere;99%

Butyric anhydride Consensus Reports

Reported in EPA TSCA Inventory.

Butyric anhydride Standards and Recommendations

DOT Classification:  8; Label: Corrosive

Butyric anhydride Specification

The Butyric anhydride, with the CAS registry number 106-31-0, is also known as Butanoic anhydride. It belongs to the product categories of Pharmaceutical Intermediates; Organics. Its EINECS registry number is 203-383-4. This chemical's molecular formula is C8H14O3 and molecular weight is 158.19. What's more, its IUPAC name is called Butanoyl butanoate. It should be stored in a cool, dry and well-ventilated place. It is a colorless liquid that smells strongly of butyric acid, formed by its reaction with the moisture in the air. It is used for the production of plastics, plasticizers, surfactants and textile auxiliaries. It is also used in food additives, flavorings, varnishes, perfumes, pharmaceuticals and disinfectants. It is used in the synthesis of butyrate ester widely used as perfumes and flavours.

Physical properties about Butyric anhydride are: (1)ACD/LogP: 1.879; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.88; (4)ACD/LogD (pH 7.4): 1.88; (5)ACD/BCF (pH 5.5): 15.78; (6)ACD/BCF (pH 7.4): 15.78; (7)ACD/KOC (pH 5.5): 250.72; (8)ACD/KOC (pH 7.4): 250.72; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 43.37 Å2; (13)Index of Refraction: 1.421; (14)Molar Refractivity: 40.916 cm3; (15)Molar Volume: 161.191 cm3; (16)Polarizability: 16.22×10-24cm3; (17)Surface Tension: 30.961 dyne/cm; (18)Density: 0.981 g/cm3; (19)Flash Point: 87.778 °C; (20)Enthalpy of Vaporization: 43.448 kJ/mol; (21)Boiling Point: 198.279 °C at 760 mmHg; (22)Vapour Pressure: 0.363 mmHg at 25 °C.

Uses of Butyric anhydride: it is used to produce other chemicals. For example, it can react with 2,5-dimethyl-furan to get 1-(2,5-dimethyl-[3]furyl)-butan-1-one. This reaction needs reagent BF3·OEt2. The reaction time is 45 min. The yield is 87 %.

Butyric anhydride can react with 2,5-dimethyl-furan to get 1-(2,5-dimethyl-[3]furyl)-butan-1-one.

When you are dealing with this chemical, you should be very careful. This chemical may destroy living tissue on contact and it reacts violently with water. It may cause burns. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice. And in case of accident or if you feel unwell seek medical advice immediately.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(OC(=O)CCC)CCC
(2) InChI: InChI=1S/C8H14O3/c1-3-5-7(9)11-8(10)6-4-2/h3-6H2,1-2H3
(3) InChIKey: YHASWHZGWUONAO-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LC inhalation > 50mg/m3 (50mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 29, 1962.
mouse LDLo oral 1gm/kg (1000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

LIVER: OTHER CHANGES
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 29, 1962.
rat LC inhalation > 50mg/m3 (50mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 4, Pg. 29, 1962.
rat LD50 oral 8790mg/kg (8790mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 321, 1986.

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