Cyclobutyl bromide supplier

Name
Cyclobutyl bromide
EINECS 224-530-9
CAS No. 4399-47-7
Article Data30
CAS DataBase
Density 1.581 g/cm³
Solubility insoluble in water
Melting Point
Formula C₄H₇Br
Boiling Point 107.1 °C at 760 mmHg
Molecular Weight 135.004
Flash Point 22.2 °C
Transport Information UN 1993 3/PG 2
Appearance Clear colourless liquid
Safety 26-36-36/37/39-16
Risk Codes 10-36/37/38-20/21/22
Molecular Structure
Hazard Symbols Xi, Xn
Synonyms Cyclobutyl bromide;AC1L2UIA;SBB070682;
PSA 0.00000
LogP 1.93380

Synthetic route

: 5162-44-7
1-bromo-4-butene

: 1229666-20-9
4-methoxy-3-pyridinesulfonamide

A: 1,4-dihydro-1-methyl-4-oxo-3-pyridinesulfonamide

B: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 84h; Reflux; regioselective reaction;	A 75% B 37.5%

...Expand

: 2516-33-8
Cyclopropylmethanol

A: 4399-47-7
Bromocyclobutane

B: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
With hydrogen bromide In 1,4-dioxane; chloroform at 10 - 20℃; for 2h;	A 9% B 74%
With phosphorus tribromide In diethyl ether at -80℃; Product distribution; variation of temperatures;
With hydrogen bromide; 1-octyl-3-methyl-imidazolium bromide at 25℃; for 0.333333h; Reagent/catalyst; Temperature;

: 42392-28-9
Cyclobutancarbonsaeure - Silbersalz

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With bromine In tetrachloromethane at -25℃; for 12h;	60%
With bromine In tetrachloromethane at 26.9℃; for 1h;	23%

: 7051-34-5
cyclopropylcarbinyl bromide

A: 5162-44-7
1-bromo-4-butene

B: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With NbCl3(N,N′-bis-(2,6-diisopropylphenyl)-1,4-diaza-2,3-dimethyl-1,3-butadiene) In benzene-d6 at 120℃; for 14h; Catalytic behavior; Inert atmosphere; Schlenk technique; Glovebox;	A 59% B 33%

: 503-17-3
dimethylacetylene

: 33742-81-3
1,1-dibromocyclobutane

A: 4399-47-7
Bromocyclobutane

B: 80204-24-6
1-Brom-1-methylcyclobutan

C: 108909-90-6
1,2-dimethylspiro(2.3)hex-1-ene

D: 6142-73-0
methylene cyclopropane

Conditions

Conditions	Yield
With methyllithium In diethyl ether at -35℃; Further byproducts given;	A n/a B 12% C 21% D 30%

...Expand

: 33742-81-3
1,1-dibromocyclobutane

A: 4399-47-7
Bromocyclobutane

B: 80204-24-6
1-Brom-1-methylcyclobutan

C: 108909-90-6
1,2-dimethylspiro(2.3)hex-1-ene

D: 6142-73-0
methylene cyclopropane

Conditions

Conditions	Yield
With dimethylacetylene; methyllithium In diethyl ether at -35℃; Further byproducts given;	A n/a B 12% C 21% D 30%

...Expand

: 2919-23-5
cyclobutanol

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With carbon tetrabromide; triphenylphosphine In diethyl ether

: 3779-29-1
diethyl cyclobutane-1,1-dicarboxylate

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
Multistep reaction;

: 498-66-8
norborn-2-ene

A: 4399-47-7
Bromocyclobutane

: 38537-30-3, 38537-32-5, 38537-61-0, 38537-64-3, 98431-04-0
7-anti-Chlor-8,9,10-trinorbornan-2-exo-ol

Conditions

Conditions	Yield
With hypochloric acid

: 3721-95-7
Cyclobutanecarboxylic acid

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With hydroxide; bromine; silver nitrate 2.) CCl4; Multistep reaction;
With [bis(acetoxy)iodo]benzene; potassium bromide In dichloromethane at 25℃; Irradiation;	86 %Chromat.

: 1506-77-0
1,1‐dichlorocyclobutane

A: 4399-47-7
Bromocyclobutane

B: 33954-15-3
1-bromocyclobut-1-ene

C: 822-35-5
cyclobutene

D: 6142-73-0
methylene cyclopropane

Conditions

Conditions	Yield
With n-butyllithium at 20℃; under 0.001 Torr; for 0.5h; Yield given. Yields of byproduct given;

...Expand

: 157-33-5
bicyclo[1.1.0]butane

A: 5162-44-7
1-bromo-4-butene

B: 4399-47-7
Bromocyclobutane

C: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
With sodium hydroxide; sodium tetrahydroborate; mercury dibromide 1.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
With hydrogen bromide Product distribution; influence of reaction time;

...Expand

: 42392-28-9
Cyclobutancarbonsaeure - Silbersalz

A: 4399-47-7
Bromocyclobutane

B: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
With bromine In tetrachloromethane at -20℃; for 1h; Yield given. Yields of byproduct given;

: 1-Bromo-1-iodocyclobutane

A: 4399-47-7
Bromocyclobutane

B: 33954-15-3
1-bromocyclobut-1-ene

C: 822-35-5
cyclobutene

D: 6142-73-0
methylene cyclopropane

Conditions

Conditions	Yield
With methyllithium at 20℃; under 0.001 Torr; for 0.5h; Yield given. Yields of byproduct given;

...Expand

mercury (II)-salt of/the/ cyclobutane-carboxylic acid: mercury (II)-salt of/the/ cyclobutane-carboxylic acid

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With carbon disulfide; bromine at -25℃;

silver salt of/the/ cyclobutane-carboxylic acid: silver salt of/the/ cyclobutane-carboxylic acid

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With tetrachloromethane; bromine at -25℃;

silver-salt of/the/ cyclobutanecarboxylic acid: silver-salt of/the/ cyclobutanecarboxylic acid

: 4399-47-7
Bromocyclobutane

Conditions

Conditions	Yield
With tetrachloromethane; bromine at -20℃;

: 2516-33-8
Cyclopropylmethanol

: 10035-10-6, 12258-64-9
hydrogen bromide

A: 5162-44-7
1-bromo-4-butene

B: 4399-47-7
Bromocyclobutane

C: 7051-34-5
cyclopropylcarbinyl bromide

...Expand

: 75-09-2
dichloromethane

: 2516-33-8
Cyclopropylmethanol

: 7789-60-8
phosphorus tribromide

A: 5162-44-7
1-bromo-4-butene

B: 4399-47-7
Bromocyclobutane

C: 7051-34-5
cyclopropylcarbinyl bromide

...Expand

: 5911-08-0
chloro(cyclopropyl)methane

A: 5162-44-7
1-bromo-4-butene

B: 4399-47-7
Bromocyclobutane

C: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
With sodium bromide; NaY zeolite In pentane at 25℃; Kinetics;	A 58 % Chromat. B 32 % Chromat. C 10 % Chromat.

...Expand

: 2516-33-8
Cyclopropylmethanol

A: 5162-44-7
1-bromo-4-butene

B: 4399-47-7
Bromocyclobutane

C: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
With hydrogen bromide; 3-ethyl-1-methyl-1H-imidazol-3-ium bromide at 80℃; for 0.333333h; Reagent/catalyst; Temperature;

...Expand

: 526214-00-6
5-methyloxazol-2-yl(phenyl)methanone

: 4399-47-7
Bromocyclobutane

: 1046818-32-9
cyclobutyl-(5-methyl-oxazol-2-yl)-phenyl-methanol

Conditions

Conditions	Yield
Stage #1: Bromocyclobutane With magnesium; iodine In tetrahydrofuran at 65℃; Inert atmosphere; Stage #2: 5-methyloxazol-2-yl(phenyl)methanone In tetrahydrofuran at 20℃; Cooling with ice;	100%
Stage #1: Bromocyclobutane With magnesium In diethyl ether at 20℃; for 1h; Heating / reflux; Stage #2: 5-methyloxazol-2-yl(phenyl)methanone In tetrahydrofuran; diethyl ether at -10 - 20℃; for 16h; Stage #3: With water; ammonium chloride In tetrahydrofuran; diethyl ether at -20℃;	38%

: 1092448-19-5
2-(2-hydroxy-3-isopropyl-benzoylamino)-indan-2-carboxylic acid ethyl ester

: 4399-47-7
Bromocyclobutane

: 1092448-20-8
2-(2-cyclobutyloxy-3-isopropyl-benzoylamino)-indan-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With caesium carbonate; potassium iodide In N,N-dimethyl-formamide at 130℃; for 2h; Microwave irradiation;	98%

: 16879-02-0
6-chloro-2-hydroxypyridine

: 4399-47-7
Bromocyclobutane

: 2-chloro-6-(cyclobutoxy)pyridine

Conditions

Conditions	Yield
With potassium carbonate at 80℃; for 16h;	98%

: 16879-02-0
6-chloro-2-pyridone

: 4399-47-7
Bromocyclobutane

: 2-chloro-6-(cyclobutoxy)pyridine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 16h;	98%

: 4399-47-7
Bromocyclobutane

: 260796-38-1
methyl 8-hydroxyquinoline-5-carboxylate

: C15H15NO3

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 95℃; for 16h;	97%

: 942473-86-1
4-bromo-3-fluorobenzenethiol

: 4399-47-7
Bromocyclobutane

: 1614246-39-7
(4-bromo-3-fluorophenyl)(cyclobutyl)sulfane

Conditions

Conditions	Yield
With caesium carbonate In dimethyl sulfoxide at 70℃; for 19h;	95%

: 4399-47-7
Bromocyclobutane

: methyl (S)-6-bromo-5-hydroxy-2-methyl-3,4-dihydroquinoline-1(2H)-carboxylate

: (S)-methyl 6-bromo-5-cyclobutoxy-2-methyl-3,4-dihydroquinoline-1(2H)-carboxylate

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile at 80℃; for 6h;	95%

: 4399-47-7
Bromocyclobutane

: 175968-15-7
4-((tert-butyldimethylsilyl)oxy)-2-fluorobenzonitrile

: 1221235-53-5
cyclobutyl(2-fluoro-4-hydroxyphenyl)methanone

Conditions

Conditions	Yield
Stage #1: Bromocyclobutane With iodine; magnesium; ethylene dibromide In diethyl ether at 20℃; Stage #2: 4-((tert-butyldimethylsilyl)oxy)-2-fluorobenzonitrile With copper(I) bromide In tetrahydrofuran; diethyl ether at 20 - 60℃; for 0.75h; Inert atmosphere; Stage #3: With hydrogenchloride; water In tetrahydrofuran; diethyl ether at 0 - 60℃; for 1h; Inert atmosphere;	95%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 4399-47-7
Bromocyclobutane

: 274-07-7
benzo[1,3,2]dioxaborole

: 2-cyclobutyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
Stage #1: benzo[1,3,2]dioxaborole With bis(cyclopentadienyl)titanium dichloride; potassium carbonate In tert-butyl methyl ether for 0.5h; Stage #2: Bromocyclobutane In tert-butyl methyl ether at 80℃; under 760.051 Torr; for 24h; Inert atmosphere; Stage #3: 2,3-dimethyl-2,3-butane diol With triethylamine In tert-butyl methyl ether at 20℃; for 1h; Inert atmosphere;	95%
Stage #1: benzo[1,3,2]dioxaborole With bis(cyclopentadienyl)titanium dichloride; potassium carbonate In tert-butyl methyl ether for 0.5h; Inert atmosphere; Glovebox; Stage #2: Bromocyclobutane In tert-butyl methyl ether at 80℃; for 24h; Sealed tube; Stage #3: 2,3-dimethyl-2,3-butane diol With triethylamine In tert-butyl methyl ether at 20℃; for 1h; Sealed tube;	95%

...Expand

: 1092448-55-9
5-formyl-2-hydroxy-3-methyl-benzoic acid methyl ester

: 4399-47-7
Bromocyclobutane

: 1092448-56-0
2-cyclobutyloxy-5-formyl-3-methyl-benzoic acid methyl ester

Conditions

Conditions	Yield
With caesium carbonate; potassium iodide In N,N-dimethyl-formamide at 110℃; for 6h;	94%

: methyl 2-hydroxy-4-nitrocinnamate

: 4399-47-7
Bromocyclobutane

: C14H15NO5

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 48h; Inert atmosphere;	94%

: 13534-89-9
2,3-dibromopyridine

: 4399-47-7
Bromocyclobutane

: 3-bromo-2-cyclobutylpyridine

Conditions

Conditions	Yield
Stage #1: Bromocyclobutane With magnesium In tetrahydrofuran at 60℃; for 3h; Stage #2: With zinc(II) chloride In tetrahydrofuran at -78 - 20℃; for 1h; Stage #3: 2,3-dibromopyridine With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 60℃; for 1h; Inert atmosphere;	94%

: 4399-47-7
Bromocyclobutane

: 930-69-8
sodium thiophenolate

: 67132-84-7
cyclobutyl phenyl sulfide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 1.5h; Heating;	93%
In N,N-dimethyl-formamide at 25℃; for 2h;	63%
In N,N-dimethyl-formamide at 0℃; Kinetics;

: 4399-47-7
Bromocyclobutane

: 7411-23-6
3,5-dibromotriazole

: 3,5-dibromo-1-cyclobutyl-1H-1,2,4-triazole

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 120℃; Sealed tube; Inert atmosphere;	93%

: 4399-47-7
Bromocyclobutane

: 1603018-85-4
6-mercaptopyridine-2-carboxylic acid ethyl ester

: 1609289-69-1
6-cyclobutylsulfanylpyridine-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile at 50℃; for 18h;	92%

: 4399-47-7
Bromocyclobutane

: 942473-85-0
3-bromo-4-fluorobenzenethiol

: (3-bromo-4-fluorophenyl)(cyclobutyl)sulfane

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide at 60℃; Inert atmosphere;	92%

: 591-20-8
3-Bromophenol

: 4399-47-7
Bromocyclobutane

: 1268713-64-9
1-bromo-3-(cyclobutoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 120℃; for 6h;	91%
With potassium carbonate In N,N-dimethyl-formamide at 65℃; for 71h; Inert atmosphere;	70%

: 4399-47-7
Bromocyclobutane

: C8H11LiSi*LiCl

: cyclobutyldimethyl(phenyl)silane

Conditions

Conditions	Yield
Stage #1: C8H11LiSi*LiCl With magnesium bromide In tetrahydrofuran at 66℃; for 0.166667h; Schlenk technique; Inert atmosphere; Stage #2: Bromocyclobutane With ferric(III) bromide; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 0℃; for 1.5h; Schlenk technique; Inert atmosphere;	91%

: 4399-47-7
Bromocyclobutane

: 40530-18-5
5-bromo-2-hydroxybenzonitrile

: 1594671-86-9
5-bromo-2-cyclobutoxybenzonitrile

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 6h; Inert atmosphere;	90%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 16h; Sealed tube;	77%

: 4399-47-7
Bromocyclobutane

: 103-72-0
phenyl isothiocyanate

: N-phenylcyclobutanecarbothioamide

Conditions

Conditions	Yield
Stage #1: Bromocyclobutane With tert.-butyl lithium at -78℃; for 2h; Inert atmosphere; Stage #2: phenyl isothiocyanate at -78 - 20℃; Inert atmosphere;	90%

: 33543-78-1
ethyl 1H-imidazole-2-carboxylate

: 4399-47-7
Bromocyclobutane

: 1-cyclobutyl-1H-imidazole-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: ethyl 1H-imidazole-2-carboxylate With potassium carbonate In N,N-dimethyl-formamide for 0.5h; Stage #2: Bromocyclobutane In N,N-dimethyl-formamide at 100℃; for 5h;	89.7%
Stage #1: ethyl 1H-imidazole-2-carboxylate With potassium carbonate In N,N-dimethyl-formamide for 0.5h; Stage #2: Bromocyclobutane In N,N-dimethyl-formamide at 100℃; for 5h;

: 4399-47-7
Bromocyclobutane

: 138851-61-3
N-(2-fluorophenyl)pyrimidin-2-amine

: N-(2-cyclobutyl-6-fluorophenyl)pyrimidin-2-amine

Conditions

Conditions	Yield
With (1,2-dimethoxyethane)dichloronickel(II); lithium tert-butoxide In 1,4-dioxane at 100℃; for 16h; Schlenk technique; Inert atmosphere;	89%
With N,N'-di-tert-butylethylenediamine; C40H32N12Ni2; lithium tert-butoxide In 1,4-dioxane at 120℃; for 16h;	57%

: 271-63-6
7-Azaindole

: 4399-47-7
Bromocyclobutane

: C11H12N2

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 90℃; for 20h;	89%

: 2581-34-2
3-methyl-4-nitrophenol

: 4399-47-7
Bromocyclobutane

: 4-cyclobutoxy-2-methyl-1-nitrobenzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 14h; Inert atmosphere;	89%

: 4399-47-7
Bromocyclobutane

: 536-74-3
phenylacetylene

: C12H13N3

Conditions

Conditions	Yield
With sodium azide; sodium L-ascorbate In water at 50℃; for 1h; Green chemistry;	88%

: 4399-47-7
Bromocyclobutane

: benzyl 3-(4-chloro-3-(((4-methoxybenzyl)oxy)methyl)phenyl)-2,2-dimethylhept-6-ynoate

: benzyl 3-(4-chloro-3-(((4-methoxybenzyl)oxy)methyl)phenyl)-5-(1-cyclobutyl-1H-1,2,3-triazol-4-yl)-2,2-dimethylpentanoate

Conditions

Conditions	Yield
Stage #1: Bromocyclobutane With sodium azide In N,N-dimethyl-formamide at 80℃; for 2h; Microwave irradiation; Stage #2: benzyl 3-(4-chloro-3-(((4-methoxybenzyl)oxy)methyl)phenyl)-2,2-dimethylhept-6-ynoate With copper(l) iodide; N-ethyl-N,N-diisopropylamine In dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol at 70℃; for 1h; Microwave irradiation;	88%

: 124-38-9
carbon dioxide

: 4399-47-7
Bromocyclobutane

: 64097-92-3
2-(1-phenylvinyl)aniline

: 4-cyclobutylmethyl-4-phenyl-1H-benzo[d][1,3]oxazin-2(4H)-one

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine In dimethyl sulfoxide at 20℃; under 760.051 Torr; for 24h; Inert atmosphere; Schlenk technique; Sealed tube; Irradiation;	88%

...Expand

: 4399-47-7
Bromocyclobutane

: 73183-34-3
bis(pinacol)diborane

: 2-cyclobutyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
With lithium tert-butoxide In N,N-dimethyl-formamide at 30℃; under 760.051 Torr; for 3h; Irradiation;	87%
With copper(I) oxide; lithium methanolate; pyrographite In ethanol at 20℃; for 12h; Inert atmosphere;	50%
With potassium methanolate; [1,3-bis(2,4,6-trimethylphenyl)imidazol]-2-ylidene; copper dichloride In tetrahydrofuran at 20℃;

6-methoxypyridine-3-ol: 6-methoxypyridine-3-ol

: 4399-47-7
Bromocyclobutane

: 5-cyclobutoxy-2-methoxypyridine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 90 - 95℃; for 16h;	87%

: 4399-47-7
Bromocyclobutane

: 2315-86-8
3-bromo-4-hydroxybenzonitrile

: 1065640-60-9
3-bromo-4-cyclobutoxybenzonitrile

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 72h;	86%
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 72h;

Cyclobutyl bromide Specification

The Cyclobutane, bromo- with CAS registry number of 4399-47-7 is also known as Cyclobutyl bromide. The IUPAC name is Cyclobutyl bromide. It belongs to product categories of Cyclobutanes & Cyclobutenes; Simple 4-Membered Ring Compounds; Cycloalkanes. Its EINECS registry number is 224-530-9. In addition, the formula is C₄H₇Br and the molecular weight is 135.00. This chemical is a clear colourless liquid that miscible with water. It may cause inflammation to the skin or other mucous membranes and may cause damage to health. Therefore this chemical should be sealed in ventilated, dry place without light at the temperature of 0-6 °C.

Physical properties about Cyclobutane, bromo- are: (1)ACD/LogP: 2.08; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.08; (4)ACD/LogD (pH 7.4): 2.08; (5)ACD/BCF (pH 5.5): 22.39; (6)ACD/BCF (pH 7.4): 22.39; (7)ACD/KOC (pH 5.5): 322.13; (8)ACD/KOC (pH 7.4): 322.13; (9)Index of Refraction: 1.526; (10)Molar Refractivity: 26.23 cm³; (11)Molar Volume: 85.3 cm³; (12)Surface Tension: 37.6 dyne/cm; (13)Density: 1.581 g/cm³; (14)Flash Point: 22.2 °C; (15)Enthalpy of Vaporization: 33.17 kJ/mol; (16)Boiling Point: 107.1 °C at 760 mmHg; (17)Vapour Pressure: 32 mmHg at 25 °C.

Preparation of Cyclobutane, bromo-: it is prepared by reaction of cyclobutanecarboxylic acid; silver (I)-compound. The reaction needs reagent Br₂ and solvent CCl₄at the temperature of -25 °C for 12 hours. The yield is about 60%.

Cyclobutane, bromo- is prepared by reaction of cyclobutanecarboxylic acid; silver (I)-compound.

Uses of Cyclobutane, bromo-: it is used to produce cyclobutyltrimethylsilane by reaction with chloro-trimethyl-silane. The reaction occurs with reagent Li and solvent tetrahydrofuran at the temperature of -20 °C for 20 hours. The yield is about 50%.

Cyclobutane, bromo- is used to produce cyclobutyltrimethylsilane by reaction with chloro-trimethyl-silane.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin. Furthermore, it is harmful by inhalation, in contact with skin and if swallowed. During using it, wear suitable protective clothing, gloves and eye/face protection. Keep away from sources of ignition as this chemical is flammable. If contact with eyes accidently, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
1. Canonical SMILES: C1CC(C1)Br
2. InChI: InChI=1S/C4H7Br/c5-4-2-1-3-4/h4H,1-3H2
3. InChIKey: KXVUSQIDCZRUKF-UHFFFAOYSA-N

Product Name

Cyclobutyl bromide

Synthetic route

Cyclobutyl bromide Specification

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