Cyclopentyl methyl ether supplier

Name
Cyclopentyl methyl ether
EINECS
CAS No. 5614-37-9
Article Data19
CAS DataBase
Density 0.86 g/cm³
Solubility Miscible with water, alcohols, ketones and hydrocarbons.
Melting Point -140°C
Formula C₆H₁₂O
Boiling Point 105.3 °C at 760 mmHg
Molecular Weight 100.161
Flash Point 6.5 °C
Transport Information UN 3271
Appearance
Safety 26
Risk Codes 11-22-36/38
Molecular Structure
Hazard Symbols F; Xn
Synonyms Ether,cyclopentyl methyl (7CI,8CI);Methoxycyclopentane;Methyl cyclopentyl ether;
PSA 9.23000
LogP 1.57540

Synthetic route

: 67-56-1
methanol

: 96-41-3
Cyclopentanol

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
With large-pore aluminosilicate zeolite ZSM-5 with Si\Al ratio of 40 at 100℃; for 6h; Reagent/catalyst; Temperature;	80.4%

: 67-56-1
methanol

: 142-29-0
cyclopentene

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
With dry acidic ion-exchange resin (SPC108) at 90℃; under 760 Torr; for 7h;	75.5%
With dry acidic ion-exchange resin (SPC118) at 90℃; under 760 Torr; for 7h;	68.9%
With H-ZSM-5-type zeolite at 150℃; under 16501.7 Torr; Temperature; Pressure; Flow reactor;	68.3%

: 512-56-1
trimethyl phosphite

: 96-41-3
Cyclopentanol

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
With PPA at 180 - 190℃; for 2h;	63%

: 67-56-1
methanol

: 120-92-3
cyclopentanone

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
With C6H16Si*AlCl3 In 2-methyltetrahydrofuran at 80℃; for 2h;	56%
With hydrogenchloride; hydrogen; platinum(IV) oxide

: 137-43-9
Cyclopentyl bromide

: 124-41-4
sodium methylate

A: 5614-37-9
cyclopentyl methyl ether

B: 142-29-0
cyclopentene

...Expand

: 930-28-9
cyclopentyl chloride

: 124-41-4
sodium methylate

A: 5614-37-9
cyclopentyl methyl ether

B: 142-29-0
cyclopentene

Conditions

Conditions	Yield
at 60℃;
With methanol at 60℃;

...Expand

: 930-28-9
cyclopentyl chloride

A: 5614-37-9
cyclopentyl methyl ether

B: 142-29-0
cyclopentene

Conditions

Conditions	Yield
With sodium methylate at 60℃;

: 5736-19-6
sodium cyclopentanolate

: 74-88-4
methyl iodide

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
With diethyl ether

: 96-41-3
Cyclopentanol

: 77-78-1
dimethyl sulfate

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
(i) NaNH2, (ii) /BRN= 635994/; Multistep reaction;

: 51422-76-5
trans-1-bromo-2-methoxycyclopentane

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
With sodium In ammonia

: 1193-67-5
1-chloromercurio-2-methoxycyclopentane

: 107-13-1
acrylonitrile

A: 5614-37-9
cyclopentyl methyl ether

: 88536-55-4, 91222-87-6
trans-2-Methoxy-1-cyclopentanpropannitril

Conditions

Conditions	Yield
With sodium hydroxide; sodium tetrahydroborate In water; N,N-dimethyl-formamide Yield given;

...Expand

: 142-29-0
cyclopentene

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: N-Bromosuccinimid 2: Na / liquid ammonia View Scheme

: 10292-51-0
1-(trichloromethyl)-cyclopentanol

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aq. KOH 2: ZnSO4 / (heating) View Scheme

: 120-92-3
cyclopentanone

cyclopentanone-vapour: cyclopentanone-vapour

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: KOH 2: aq. KOH 3: ZnSO4 / (heating) View Scheme

: 96-41-3
Cyclopentanol

: 74-88-4
methyl iodide

: 5614-37-9
cyclopentyl methyl ether

Conditions

Conditions	Yield
Stage #1: Cyclopentanol With sodium hydride In DMF (N,N-dimethyl-formamide) at 20 - 120℃; for 2h; Stage #2: methyl iodide In DMF (N,N-dimethyl-formamide) at 50 - 120℃; for 5h;

: 673-32-5
1-Phenylprop-1-yne

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(1-methoxy-1-phenylprop-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	99%

...Expand

: 21020-27-9
4-methylpent-2-yne

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(2-methoxy-4-methylpent-2-en-3-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	99%

...Expand

: 622-76-4
1-phenyl-1-butyne

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(1-methoxy-1-phenylbut-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 180071-98-1
1-(p-tolyl)-1-hexyne

: (E)-1-(1-methoxy-1-(p-tolyl)hex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 536-74-3
phenylacetylene

: (E)-1-(2-methoxy-2-phenylvinyl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 766-97-2
4-n-methylphenylacetylene

: (E)-1-(2-methoxy-2-(p-tolyl)vinyl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

...Expand

: 1942-45-6
4-Octyne

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(5-methoxyoct-4-en-4-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	97%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: C23H45IrNOP2(1+)*C32H12BF24(1-)

: C25H45IrNOP2(1+)*C32H12BF24(1-)

Conditions

Conditions	Yield
With tert-butylethylene at 60℃; for 1.5h; Glovebox; Inert atmosphere; Sealed tube;	97%

: 5614-37-9
cyclopentyl methyl ether

: 766-82-5
1-ethynyl-3-methyl-benzene

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(2-methoxy-2-(m-tolyl)vinyl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	96%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 112545-94-5
1-chloro-4-(1-hexynyl)benzene

: (E)-1-(1-(4-chlorophenyl)-1-methoxyhex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	95%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 112545-96-7
1-(hex-1-yn-1-yl)-3-methoxybenzene

: (E)-1-(1-methoxy-1-(3-methoxyphenyl)hex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	95%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: N,N-dimethyl-8-phenyloct-7-ynamide

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-7-(3,3-bis(trifluoromethyl)-1λ3-benzo[d][1,2]iodaoxol-1(3H)-yl)-8-methoxy-N,N-dimethyl-8-phenyloct-7-enamide

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	94%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 78-80-8
2-methyl-1-buten-3-yne

: (E)-1-(2-methoxy-3-methylbuta-1,3-dien-1-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	94%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 1,1'-biphenyl-1-hexyne

: (E)-1-(1-([1,1'-biphenyl]-4-yl)-1-methoxyhex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	93%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 19482-59-8
2-(hex-1-ynyl)thiophene

: (E)-1-(1-methoxy-1-(thiophen-2-yl)hex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	93%

...Expand

: 766-98-3
1-ethynyl-4-fluorobenzene

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(2-(4-fluorophenyl)-2-methoxyvinyl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	92%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 168213-37-4
1,4-di(hex-1-yn-1-yl)benzene

: (E)-1-(1-(4-(hex-1-yn-1-yl)phenyl)-1-methoxyhex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	91%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-2-(1-hexyne-1-yl)benzene

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(1-(2-fluorophenyl)-1-methoxyhex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	91%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 693-02-7
hex-1-yne

: (E)-1-(2-methoxyhex-1-en-1-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	91%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 705-31-7
4-trifluoromethylphenylacetylene

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(2-methoxy-2-(4-(trifluoromethyl)phenyl)vinyl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	87%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 768-70-7
1-ethynyl-3-methoxybenzene

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: (E)-1-(2-methoxy-2-(3-methoxyphenyl)vinyl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	85%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 100-47-0
benzonitrile

: 53226-42-9
N-cyclopentylbenzamide

Conditions

Conditions	Yield
With iron(III) perchlorate hydrate In neat (no solvent) at 100℃; for 2h; Ritter Amidation;	84%

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 131558-77-5
4-(hexyn-1-yl)anisole

: (E)-1-(1-methoxy-1-(4-methoxyphenyl)hex-1-en-2-yl)-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	84%

...Expand

: 24886-73-5
1-Azidoadamantane

: 5614-37-9
cyclopentyl methyl ether

: cyclopentyl N-(adamantyl)formimidate

Conditions

Conditions	Yield
With tert-butylethylene; C27H47IrNP2(1+)*C32H12BF24(1-) at 90℃; for 22h; Reagent/catalyst; Temperature; Glovebox; Inert atmosphere; Irradiation; Sealed tube;	84%

: 5614-37-9
cyclopentyl methyl ether

: 1641528-26-8
2,2,2-trichloroethyl 2-(4-bromophenyl)-2-diazoacetate

: 2,2,2-trichloroethyl (R)-2-(4-bromophenyl)-3-(cyclopentyloxy)propanoate

Conditions

Conditions	Yield
With dirhodium tetrakis[(R)-(1-(biphenyl)-2,2-diphenylcyclopropanecarboxylate)] In dichloromethane at 0℃; enantioselective reaction;	83%

: 5614-37-9
cyclopentyl methyl ether

: 100-09-4
4-methoxybenzoic acid

: cyclopentyloxymethyl 4-methoxybenzoate

Conditions

Conditions	Yield
With di-tert-butyl peroxide; Fe3O(1,4-benzenedicarboxylate)3 at 120℃; for 3h; High pressure;	83%

: 5614-37-9
cyclopentyl methyl ether

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: 139697-98-6
1-(3-ethynylphenyl) ethan-1-one

: (E)-1-(3-(2-(3,3-bis(trifluoromethyl)-1λ3-benzo[d][1,2]iodaoxol-1(3H)-yl)-1-methoxyvinyl)phenyl)ethan-1-one

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	83%

...Expand

: 5614-37-9
cyclopentyl methyl ether

: 10602-06-9
methyl 3-ethynylbenzoate

: 1-fluoro-3,3-bis(trifluoromethyl)-1,3-dihydro-1λ3-benzo[d][1,2]iodaoxole

: methyl (E)-3-(2-(3,3-bis(trifluoromethyl)-1λ3-benzo[d][1,2]iodaoxol-1(3H)-yl)-1-methoxyvinyl)benzoate

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction;	82%

...Expand

: 1663-39-4
tert-Butyl acrylate

: 5614-37-9
cyclopentyl methyl ether

: 623-00-7
4-bromobenzenecarbonitrile

: tert-butyl 2-(4-cyanophenyl)-3-(1-methoxycyclopentyl)propanoate

Conditions

Conditions	Yield
With dipotassium hydrogenphosphate; 4-(4-methoxybenzoyl)benzonitrile; 4,4'-di-tert-butyl-2,2'-bipyridine nickel(II) bromide for 24h; Catalytic behavior; Reagent/catalyst; Wavelength; Irradiation; Inert atmosphere; Sealed tube; regioselective reaction;	81%

...Expand

Cyclopentyl methyl ether Specification

The Cyclopentyl methyl ether, with the cas registry number 5614-37-9, has the IUPAC name of methoxycyclopentane. It is a kind of clear liquid and should be stored in a cool and dry place. In addition, the molecular formula is C₆H₁₂O and the molecular weight is 100.16.

Physical properties about Cyclopentyl methyl ether are: (1)ACD/LogP: 1.41; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.41; (4)ACD/LogD (pH 7.4): 1.41; (5)ACD/BCF (pH 5.5): 6.99; (6)ACD/BCF (pH 7.4): 6.99; (7)ACD/KOC (pH 5.5): 140.01; (8)ACD/KOC (pH 7.4): 140.01; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 9.23 Å²; (13)Index of Refraction: 1.423; (14)Molar Refractivity: 29.49 cm³; (15)Molar Volume: 115.7 cm³; (16)Polarizability: 11.69×10^-24cm³; (17)Surface Tension: 25 dyne/cm; (18)Density: 0.86 g/cm³; (19)Flash Point: 6.5 °C; (20)Enthalpy of Vaporization: 33 kJ/mol; (21)Boiling Point: 105.3 °C at 760 mmHg; (22)Vapour Pressure: 34.6 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable and harmful if swallowed. What's more, it irritates to eyes and skin. Therefore, if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O(C)C1CCCC1
(2)Std. InChI: InChI=1S/C6H12O/c1-7-6-4-2-3-5-6/h6H,2-5H2,1H3
(3)Std. InChIKey: SKTCDJAMAYNROS-UHFFFAOYSA-N

Product Name

Cyclopentyl methyl ether

Synthetic route

Cyclopentyl methyl ether Specification

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