Product Name

  • Name

    (dimethyl)[10H-pyrido[3,2-b][1,4]benzothiazine-10-propyl]ammonium chloride

  • EINECS
  • CAS No. 1225-65-6
  • Article Data1
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point 177-178° with sintering ~176°; mp 108-112°
  • Formula C16H19 N3 S . Cl H
  • Boiling Point
  • Molecular Weight 321.874
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1225-65-6 ((dimethyl)[10H-pyrido[3,2-b][1,4]benzothiazine-10-propyl]ammonium chloride)
  • Hazard Symbols 3
  • Synonyms 10H-Pyrido[3,2-b][1,4]benzothiazine,10-[3-(dimethylamino)propyl]-, monohydrochloride (8CI);10H-Pyrido[3,2-b][1,4]benzothiazine-10-propanamine, N,N-dimethyl-,monohydrochloride (9CI); AY 56031; Azacon; D 206; Dominal forte; Dominalhydrochloride; Prothipendyl hydrochloride; Prothipendyl monohydrochloride;Tolnate
  • PSA 41.43000
  • LogP 1.15470

Dominal hydrochloride Chemical Properties

Molecule structure of Dominal hydrochloride (CAS NO.1225-65-6):

IUPAC Name: N,N-Dimethyl-3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-1-amine hydrochloride 
Molecular Weight: 321.8681 g/mol
Molecular Formula: C16H20ClN3S 
Density: 1.168 g/cm3 
Boiling Point: 430.8 °C at 760 mmHg 
Flash Point: 214.3 °C
Index of Refraction: 1.621
Molar Refractivity: 85.95 cm3
Molar Volume: 244.1 cm3
Polarizability: 34.07×10-24 cm3
Surface Tension: 48.7 dyne/cm 
Enthalpy of Vaporization: 68.63 kJ/mol
Vapour Pressure: 1.26E-07 mmHg at 25 °C
H-Bond Donor: 1
H-Bond Acceptor: 3
Rotatable Bond Count: 4
Exact Mass: 321.106646
MonoIsotopic Mass: 321.106646
Topological Polar Surface Area: 19.4
Heavy Atom Count: 21
Complexity: 310
Canonical SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1N=CC=C3.Cl
InChI: InChI=1S/C16H19N3S.ClH/c1-18(2)11-6-12-19-13-7-3-4-8-14(13)20-15-9-5-10-17-16(15)19;/h3-5,7-10H,6,11-12H2,1-2H3;1H
InChIKey: CQJSAKJMCVSEGU-UHFFFAOYSA-N
EINECS of Dominal hydrochloride (CAS NO.1225-65-6): 214-958-4

Dominal hydrochloride Toxicity Data With Reference

1.    

orl-rat LD50:610 mg/kg

     27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,292.
2.    

ipr-rat LD50:115 mg/kg

     27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,292.
3.    

scu-rat LD50:1323 mg/kg

     27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,292.
4.    

ivn-rat LD50:110 mg/kg

     27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,292.

Dominal hydrochloride Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.

Dominal hydrochloride Specification

 Dominal hydrochloride (CAS NO.1225-65-6) is also called ((4-Dimethylaminopropylpyrido (3,2b) benzothiazine))
hydrochloride ; 10-(3-Dimethylaminopropyl)-1-azaphenothiazine hydrochloride ; AY-56031 ; Azacon ; Dominal forte ; N,N-Dimethyl-10H-pyrido(3,2-b)(1,4)benzothiazine-10-propanamine, monohydrochloride ; Prothipendyl HCl ; Prothipendyl hydrochloride ; Tolnate ; UNII-7610629RVH .

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View