EDROPHONIUM CHLORIDE supplier

Name
Edrophonium chloride
EINECS 204-138-4
CAS No. 116-38-1
Density g/cm³
Solubility Soluble in water (50mg/ml)
Melting Point 162-163 °C (decomp)
Formula C10H16 N O . Cl
Boiling Point °Cat760mmHg
Molecular Weight 201.696
Flash Point °C
Transport Information
Appearance White powder
Safety Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl⁻, NH₃, and NO_x. See also CHLORIDES.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Ammonium,ethyl(m-hydroxyphenyl)dimethyl-, chloride (8CI); Benzenaminium,N-ethyl-3-hydroxy-N,N-dimethyl-, chloride (9CI);Ethyl(m-hydroxyphenyl)dimethylammonium chloride (6CI,7CI); Antirex;Dimethylethyl(3-hydroxyphenyl)ammonium chloride; Edrophonium chloride; Enlon;Ethyl(3-hydroxyphenyl)dimethylammonium chloride; Reversol; Tensilon; Tensilon chloride
PSA 20.23000
LogP -1.01700

Synthetic route

: 75-03-6
ethyl iodide

: 99-07-0
3-Dimethylaminophenol

: 116-38-1
edrophonium chloride

: 74-96-4
ethyl bromide

: 99-07-0
3-Dimethylaminophenol

: 116-38-1
edrophonium chloride

: 116-38-1
edrophonium chloride

: 145577-00-0
[11C]methyl triflate

: [11C]methyl-edrophonium

Conditions

Conditions	Yield
With sodium hydrogencarbonate In dichloromethane; acetonitrile at 70 - 80℃;

EDROPHONIUM CHLORIDE Chemical Properties

IUPAC Name: Ethyl-(3-hydroxyphenyl)-dimethylazanium chloride
The MF of Edrophonium chloride (CAS NO.116-38-1) is C₁₀H₁₆ClNO.

The MW of Edrophonium chloride (CAS NO.116-38-1) is 201.69.
Synonyms of Edrophonium chloride (CAS NO.116-38-1): Antirex ; Dimethylethyl(M-hydroxyphenyl)-ammoniuchloride ; Ethyl(M-hydroxyphenyl)dimethyl-ammoniuchloride ; N-ethyl-3-hydroxy-N,N-dimethyl-benzenaminiuchloride ; Tensilon ; Ethyl(3-hydroxyphenyl)dimethylammonium chloride
EINECS: 204-138-4

EDROPHONIUM CHLORIDE Uses

Edrophonium chloride (CAS NO.116-38-1) prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction.It is used to differentiate myasthenic crisis from cholinergic crisis.

EDROPHONIUM CHLORIDE Toxicity Data With Reference

1.	ipr-mus LD50:30 mg/kg	PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 10 (1976),327.
2.	scu-mus LD50:52 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 123 (1958),121.
3.	ivn-mus LD50:15 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),133.

EDROPHONIUM CHLORIDE Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl⁻, NH₃, and NO_x. See also CHLORIDES.Safety information of Edrophonium chloride (CAS NO.116-38-1):
WGK Germany 3
RTECS BQ5870000

EDROPHONIUM CHLORIDE Specification

Edrophonium is a readily reversible acetylcholinesterase inhibitor. It prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase, mainly at the neuromuscular junction. It is sold under the trade names Tensilon, Enlon and Reversol.

Product Name

Edrophonium chloride