Product Name

  • Name

    Erythromycin 2'-propionate dodecyl sulfate

  • EINECS 222-532-4
  • CAS No. 3521-62-8
  • Density 1.0053 (rough estimate)
  • Solubility Freely soluble in organic solvents, practically insoluble in water /n
  • Melting Point 135-140 °C dec.
  • Formula C52H97NO18S
  • Boiling Point 827.7 °C at 760 mmHg
  • Molecular Weight 1000.34
  • Flash Point 454.4 °C
  • Transport Information
  • Appearance Long needles
  • Safety 22-36-26
  • Risk Codes 22-42/43-36/37/38
  • Molecular Structure Molecular Structure of 3521-62-8 (Erythromycin 2'-propionate dodecyl sulfate)
  • Hazard Symbols HarmfulXn,IrritantXi
  • Synonyms Sulfuricacid, monododecyl ester;LP 35;Lauryl alcohol sulfate;Lauryl hydrogen sulfate;
  • PSA 271.96000
  • LogP 7.55400

Erythromycin estolate Chemical Properties

Empirical Formula: C52H97NO18S
Molecular Weight: 1056.3875 
EINECS: 222-532-4
Flash Point: 454.4 °C
Enthalpy of Vaporization: 136.89 kJ/mol
Boiling Point: 827.7 °C at 760 mmHg
Vapour Pressure: 8.87E-32 mmHg at 25 °C
Melting point: 135-140 °C
Appearance: Long needles
Structure of Erythromycin estolate (CAS NO.3521-62-8):
                         
IUPAC Name: [(2S,3R,4S,6R)-4-(Dimethylamino)-2-[[(1R,2R,4R,6R,7R,8S,9R,12R,13S,14S)-9-ethyl-2,7,8-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,6,8,12,14-hexamethyl-5,11-dioxo-10-oxacyclotetradec-1-yl]oxy]-6-methyloxan-3-yl] propanoate ; Dodecyl hydrogen sulfate
Product Category of Erythromycin estolate (CAS NO.3521-62-8): Intermediates & Fine Chemicals;Pharmaceuticals

Erythromycin estolate Uses

 Erythromycin estolate (CAS NO.3521-62-8) has been used as an antibacterial agent and is often used for people who have an allergy to penicillins.

Erythromycin estolate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 6450mg/kg (6450mg/kg)   Drugs in Japan Vol. -, Pg. 211, 1990.
mouse LD50 subcutaneous > 6450mg/kg (6450mg/kg)   Drugs in Japan Vol. -, Pg. 211, 1990.
rat LD50 oral 1447mg/kg (1447mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat LD50 subcutaneous > 6450mg/kg (6450mg/kg)   Drugs in Japan Vol. -, Pg. 211, 1990.
women TDLo unreported 100mg/kg/5D-I (100mg/kg) LIVER: CHANGE IN GALL BLADDER STRUCTURE OR FUNCTION Clinical Pharmacology and Therapeutics Vol. 6, Pg. 788, 1965.

Erythromycin estolate Safety Profile

Hazard Codes: HarmfulXn,IrritantXi
Risk Statements: 22-42/43-36/37/38 
R22:Harmful if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 22-36-26 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

Erythromycin estolate Specification

It is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin. Erythromycin estolate (CAS NO.3521-62-8) inhibits the cytochrome P450 system, particularly the CYP3A4 isozyme, which can cause it to affect the metabolism of many different drugs. It is not recommended when using clindamycin containing products, even topical products such as duac or benzaclin. In general, the simultaneous use two different erythromycin derivatives should be avoided as drugs in this macrolide family share a common mechanism of action.

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View