Product Name

  • Name

    Erythromycin,hydrochloride (8CI,9CI)

  • EINECS
  • CAS No. 14271-02-4
  • Density g/cm3
  • Solubility
  • Melting Point
  • Formula C37H67 N O13 . Cl H
  • Boiling Point 818.4°Cat760mmHg
  • Molecular Weight 770.51
  • Flash Point 448.8°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also ERYTHROMYCIN.
  • Risk Codes
  • Molecular Structure Molecular Structure of 14271-02-4 (Erythromycin,hydrochloride (8CI,9CI))
  • Hazard Symbols
  • Synonyms Oxacyclotetradecane,erythromycin deriv.
  • PSA 193.91000
  • LogP 2.58760

Erythromycin hydrochloride Chemical Properties

Molecule structure of Erythromycin hydrochloride (CAS NO.14271-02-4) :

IUPAC Name: (2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-ethyl-3,4,12-trihydroxy-9-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,8,10,12,14-hexamethyl-6-oxacyclotetradecane-1,7-dione hydrochloride 
Molecular Weight: 770.38772 g/mol
Molecular Formula: C37H68ClNO13 
Boiling Point: 818.4 °C at 760 mmHg
Flash Point: 448.8 °C
Enthalpy of Vaporization: 135.4 kJ/mol 
Vapour Pressure: 4.94E-31 mmHg at 25 °C 
H-Bond Donor: 6
H-Bond Acceptor: 14
Rotatable Bond Count: 7
Tautomer Count: 3
Exact Mass: 769.437919
MonoIsotopic Mass: 769.437919
Topological Polar Surface Area: 194
Heavy Atom Count: 52
Complexity: 1180 
Defined Atom StereoCenter Count: 18
Isomeric SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H]
(C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O.Cl
InChI: InChI=1S/C37H67NO13.ClH/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;1H/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1
InChIKey of Erythromycin hydrochloride (CAS NO.14271-02-4) : BXBSPTIDIMGJNO-YZPBMOCRSA-N

Erythromycin hydrochloride Toxicity Data With Reference

1.    

scu-rat LD50:1442 mg/kg

     JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 41 (1952),555.
2.    

ivn-rat LD50:209 mg/kg

     JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 41 (1952),555.
3.    

orl-mus LD50:2927 mg/kg

     JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 41 (1952),555.
4.    

ipr-mus LD50:490 mg/kg

     JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 41 (1952),555.
5.    

scu-mus LD50:1849 mg/kg

     JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 41 (1952),555.
6.    

ivn-mus LD50:377 mg/kg

     USXXAM    United States Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #4393053 .
7.    

ivn-rbt LD50:183 mg/kg

     JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 41 (1952),555.

Erythromycin hydrochloride Safety Profile

Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also ERYTHROMYCIN.

Erythromycin hydrochloride Specification

 Erythromycin hydrochloride (CAS NO.14271-02-4) is also called Ilotycin hydrochloride .

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View