Hexyl acrylate supplier | CasNO.2499-95-8

Name
N-HEXYL ACRYLATE
EINECS
CAS No. 2499-95-8
Article Data15
CAS DataBase
Density 0.889g/cm³
Solubility 57.4mg/L at 20℃
Melting Point -45°C
Formula C9H16 O2
Boiling Point 88-90 °C24 mm Hg(lit.)
Molecular Weight 156.225
Flash Point 58.3°C
Transport Information
Appearance clear colorless liquid
Safety Mildly toxic by skin contact. See also ESTERS. When heated to decomposition it emits acrid smoke and fumes.
Risk Codes 36/37/38-43-51/53
Molecular Structure
Hazard Symbols
Synonyms Acrylicacid, hexyl ester (6CI,7CI,8CI); Hexyl 2-propenoate; Hexyl acrylate; NSC 11786;n-Hexyl acrylate
PSA 26.30000
LogP 2.29590

Synthetic route

: 3295-94-1
hexyl 2-propenyl ether

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; [bis(acetoxy)iodo]benzene; magnesium acetate In decane; butyl butyrate at 0℃; chemoselective reaction;	91%

: 814-68-6
acryloyl chloride

: 111-27-3
hexan-1-ol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 0.5h; Inert atmosphere;	83.4%
With triethylamine In tetrahydrofuran at 10 - 20℃; for 3h;	81%
With potassium carbonate In tetrahydrofuran
With triethylamine In chloroform at 10℃; for 12h;

: 133122-99-3
acrylic acid-6-iodohexyl ester

A: 2499-95-8
n-hexyl acrylate

B: 797-29-5
1,11-dioxacycloisocosane

C: 6008-27-1
oxecan-2-one

Conditions

Conditions	Yield
With sodium cyanoborohydride In methanol for 3h; Ambient temperature; Irradiation; Yields of byproduct given;	A n/a B n/a C 74%
With sodium cyanoborohydride In methanol for 3h; Ambient temperature; Irradiation; Yield given;	A n/a B n/a C 74%

...Expand

: 79-10-7
acrylic acid

: 111-27-3
hexan-1-ol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene for 8h; Reflux;	62.6%
With alkanesulfonic acid; toluene at 120℃;
With zirconium(IV) oxychloride at 50℃; for 24h;	61 % Chromat.

: 2177-18-6
vinyl acrylate

: 111-27-3
hexan-1-ol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
In 2,2,4-trimethylpentane at 37℃; immobilized lipase from Candida cylindracea;	40%
In 2,2,4-trimethylpentane at 37℃; immobilized lipase from Candida cylindracea; transesterification, other alcohols; also with vinyl methacrylate;	40%

: 292638-85-8
acrylic acid methyl ester

: 111-27-3
hexan-1-ol

: 2499-95-8
n-hexyl acrylate

: 629-11-8
1,6-hexanediol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 47percent HBr / toluene / Heating 2: NaI / acetone / Ambient temperature 3: p-TolSO3H / benzene / Heating 4: NaBH3CN / methanol / 3 h / Ambient temperature; Irradiation View Scheme

: 4286-55-9
1-bromo-6-hexanol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: NaI / acetone / Ambient temperature 2: p-TolSO3H / benzene / Heating 3: NaBH3CN / methanol / 3 h / Ambient temperature; Irradiation View Scheme

: 40145-10-6
1-iodohexan-6-ol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: p-TolSO3H / benzene / Heating 2: NaBH3CN / methanol / 3 h / Ambient temperature; Irradiation View Scheme

: 111-27-3
hexan-1-ol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydride / tetrahydrofuran 2: tert.-butylhydroperoxide; [bis(acetoxy)iodo]benzene; magnesium acetate / decane; butyl butyrate / 0 °C View Scheme

: 140-88-5
ethyl acrylate

: 111-27-3
hexan-1-ol

: 2499-95-8
n-hexyl acrylate

Conditions

Conditions	Yield
In neat (no solvent) at 79.84℃; for 5h;

: 140-88-5
ethyl acrylate

: 111-27-3
hexan-1-ol

A: 2499-95-8
n-hexyl acrylate

B: 14144-59-3
ethyl 3-(hexyloxy)propanoate

Conditions

Conditions	Yield
In neat (no solvent) at 79.84℃; for 1h; Reagent/catalyst; Solvent; Temperature;

...Expand

: 2499-95-8
n-hexyl acrylate

: 105-53-3
diethyl malonate

: 2-ethoxycarbonyl-pentanedioic acid 1-ethyl ester 5-hexyl ester

Conditions

Conditions	Yield
Mg-La mixed oxides In N,N-dimethyl-formamide at 24.85℃; for 3.5h; Michael addition;	99%

: 111-31-9
Hexanethiol

: 2499-95-8
n-hexyl acrylate

: 1236160-83-0
C15H30O2S

Conditions

Conditions	Yield
With hexan-1-amine at 20℃; for 3h; Kinetics; Reagent/catalyst; Thio-Michael reaction; Neat (no solvent);	99%
With Dimethyl(phenyl)phosphine In neat (no solvent) for 0.5h; Reagent/catalyst; Michael Addition;

: 79-24-3
Nitroethane

: 2499-95-8
n-hexyl acrylate

: 4-nitro-pentanoic acid hexyl ester

Conditions

Conditions	Yield
Mg-La mixed oxides In N,N-dimethyl-formamide for 3.5h; Michael addition;	98%

: 2499-95-8
n-hexyl acrylate

: 16215-21-7
butyl 3-mercaptopropionate

: C16H30O4S

Conditions

Conditions	Yield
With cyclohexanone; 1-(9-fluorenylmethoxycarbonyl)-diethylamine for 0.0833333h; Reagent/catalyst; Irradiation;	98%

: 98-10-2
benzenesulfonamide

: 2499-95-8
n-hexyl acrylate

: N,N-di((2-carbo-n-hexyloxy)ethyl)benzenesulfonamide

Conditions

Conditions	Yield
With potassium fluoride; tetrabutylammomium bromide at 130℃; for 0.233333h; Microwave irradiation; Neat (no solvent);	97%

: 2499-95-8
n-hexyl acrylate

: 4241-66-1
4-Iodobenzenesulphonyl Fluoride

: hexyl (E)-3-(4-(fluorosulfonyl)phenyl)acrylate

Conditions

Conditions	Yield
With tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate In N,N-dimethyl-formamide at 20℃; for 48h; Inert atmosphere; Sealed tube;	97%

: 2499-95-8
n-hexyl acrylate

: 76656-52-5
1,6-diiodopyrene

: 658858-93-6
di-n-hexyl 1,6-pyrenedipropenoate

Conditions

Conditions	Yield
With palladium diacetate; triethylamine; tris-(o-tolyl)phosphine at 120℃; for 6h;	94%

: 2499-95-8
n-hexyl acrylate

: 945761-25-1
1-iodosinomenine

: C28H37NO6

Conditions

Conditions	Yield
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 85℃; for 0.333333h; Time; Heck Reaction;	94%

: 2499-95-8
n-hexyl acrylate

: 55-21-0
benzamide

: 1116115-87-7
hexyl 3-benzamidopropanoate

Conditions

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate for 0.25h; aza-Michael addition; microwave irradiation;	93%

: 3140-93-0
2,3-dibromothiophen

: 2499-95-8
n-hexyl acrylate

: C22H32O4S

Conditions

Conditions	Yield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 120℃; for 48h; Heck reaction;	92%

: 3140-93-0
2,3-dibromothiophen

: 2499-95-8
n-hexyl acrylate

: 1184839-42-6
dihexyl (2E,2'E)-3,3'-(thiophene-2,3-diyl)diacrylate

Conditions

Conditions	Yield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 120℃; for 48h; Heck Reaction; Inert atmosphere;	92%

: 2499-95-8
n-hexyl acrylate

: 80-17-1
benzenesufonyl hydrazide

: hexyl 3-(phenylsulfonyl)propanoate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In neat (no solvent) at 75℃; for 3h; Michael Addition; Green chemistry;	92%

: 98-10-2
benzenesulfonamide

: 2499-95-8
n-hexyl acrylate

A: hexyl 3-(phenylsulfonamido)propanoate

B: N,N-di((2-carbo-n-hexyloxy)ethyl)benzenesulfonamide

Conditions

Conditions	Yield
With aluminum oxide; potassium fluoride; tetrabutylammomium bromide at 110℃; for 0.166667h; Michael condensation; Microwave irradiation;	A 91% B 6%
With 1-n-butyl-3-methylimidazolim bromide; zinc(II) oxide at 110℃; for 0.0833333h; Michael addition reaction; microwave irradiation;	A 85% B 9%

...Expand

: 2499-95-8
n-hexyl acrylate

: 1576-47-2
2-naphthalenesulphonamide

A: hexyl 3-(naphthalene-2-suylfonamido)propanoate

B: dihexyl 3,3'-(naphthalene-2-sulfonylazanediyl)dipropanoate

Conditions

Conditions	Yield
With aluminum oxide; potassium fluoride; tetrabutylammomium bromide at 110℃; for 0.166667h; Michael condensation; Microwave irradiation;	A 91% B 6%

...Expand

: 2499-95-8
n-hexyl acrylate

: 1576-35-8
toluene-4-sulfonic acid hydrazide

: hexyl 3-tosylpropanoate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In neat (no solvent) at 75℃; for 3h; Michael Addition; Green chemistry;	90%

: 6714-68-7
spiro[1,3-dioxolane-2,3'-indolin]-2'-one

: 2499-95-8
n-hexyl acrylate

: 1380216-32-9
C19H25NO5

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutylammomium bromide at 80 - 90℃; for 1h; Michael condensation; neat (no solvent);	89%

: 30544-34-4
2,3-dibromofuran

: 2499-95-8
n-hexyl acrylate

: 1338800-56-8
dihexyl (2E,2'E)-3,3'-(furan-2,3-diyl)diacrylate

Conditions

Conditions	Yield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 120℃; for 36h; Heck reaction; Inert atmosphere;	88%

: 2499-95-8
n-hexyl acrylate

: 6284-40-8
1-deoxy-1-(methylamino)-D-glucitol

: C16H33NO7

Conditions

Conditions	Yield
In 1,4-dioxane; water at 50℃; for 5h;	86%

: 54113-42-7
2,3-dibromo-5-(ethoxycarbonyl)furan

: 2499-95-8
n-hexyl acrylate

: 1338800-62-6
dihexyl (2E,2'E)-3,3'-[5-(ethoxycarbonyl)furan-2,3-diyl]diacrylate

Conditions

Conditions	Yield
With palladium diacetate; triethylamine; XPhos In N,N-dimethyl-formamide at 100℃; for 24h; Heck reaction; Inert atmosphere;	85%

: 2499-95-8
n-hexyl acrylate

: 123055-54-9
1.3′,3′,6′,6′-tetramethyl-3′,4′,6′,7′-tetrahydrospiro[indoline-3, 9′-xanthene]-1′, 2, 8′ (2′H, 5′H)-trione

: hexyl 3-(3',3',6',6'-tetramethyl-1',2,8'-trioxo-1',2',3',4',5',6',7',8'-octahydrospiro[indoline-3,9'-xanthen]-1-yl)propanoate

Conditions

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate for 0.0333333h; Michael Addition; Heating; Green chemistry;	85%

: 611-32-5
8-methylquinoline

: 2499-95-8
n-hexyl acrylate

: hexyl 4-(quinolin-8-yl)butanoate

Conditions

Conditions	Yield
With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; 1,1,1,3',3',3'-hexafluoro-propanol; Trimethylacetic acid at 120℃; for 24h; Reagent/catalyst; Inert atmosphere; Glovebox; regioselective reaction;	85%

: 2499-95-8
n-hexyl acrylate

: 100-52-7
benzaldehyde

: 144261-66-5
3-phenyl-3-hydroxy-2-methylene-propanoic acid hexyl ester

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane for 216h; Ambient temperature;	82%

: C68H85N4O2B

: 2499-95-8
n-hexyl acrylate

: n-hexyl (E)-3-[5,10,15-tris(3,5-di-tert-butylphenyl)porphyrin-2-yl]prop-2-enoate

Conditions

Conditions	Yield
With [Rh(OH)(cod)]2 In 1,4-dioxane; water at 100℃; for 16h; Heck-type addition; Inert atmosphere;	82%

: 2499-95-8
n-hexyl acrylate

: 128746-62-3
2,3-dibromo-1-methyl-1H-indole

: 1186316-09-5
di(n-hexyl) 9-methyl-2,9-dihydro-1H-carbazole-2,3-dicarboxylate

Conditions

Conditions	Yield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 120℃; for 48h; domino Heck reaction - 6ϖ-electrocyclization; Inert atmosphere;	81%
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 120℃; for 48h; domino two-fold Heck/6ϖ-electrocyclization reaction; Inert atmosphere;	81%

: 2499-95-8
n-hexyl acrylate

: 2445-76-3
n-hexyl propionate

Conditions

Conditions	Yield
With C51H71CoN4O14(1+)*ClO4(1-); trifluoroacetic acid In acetonitrile at 20℃; Electrolysis; Inert atmosphere;	81%
With methanol for 24h; UV-irradiation;	60%
With [Rh(OH)(cod)]2; 2-(hex-1-yn-1-yl)phenol at 90℃; for 6h;
With C18H9BF6*C4H8O; hydrogen In dichloromethane-d2 at -196.16 - 25℃; under 3000.3 Torr; for 36h; Inert atmosphere; Schlenk technique; Glovebox;	> 95 %Spectr.

: 128-08-5
N-Bromosuccinimide

: 2499-95-8
n-hexyl acrylate

: (E)-hexyl 2-bromo-3-(2,5-dioxopyrrolidin-1-yl)acrylate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In acetonitrile at 20℃; for 12h; stereoselective reaction;	81%

: 2499-95-8
n-hexyl acrylate

: 98-80-6
phenylboronic acid

: 3488-00-4
n-hexyl cinnamate

Conditions

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate; copper(II) sulfate; palladium dichloride In water at 85℃; for 10h; Heck Reaction; Schlenk technique; stereoselective reaction;	81%

: 25055-55-4
2,3,5,6-tetrabromo-1-methyl-1H-indole

: 2499-95-8
n-hexyl acrylate

: 1314799-02-4
di(n-hexyl) 6,7-bis((E)-3-(hexyloxy)-3-oxoprop-1-enyl)-9-methyl-2,9-dihydro-1H-carbazole-2,3-dicarboxylate

Conditions

Conditions	Yield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine In N,N-dimethyl-formamide at 120℃; for 48h; domino two-fold Heck/6ϖ-electrocyclization reaction; Inert atmosphere;	80%

Hexyl acrylate Chemical Properties

Product Name: Hexyl acrylate (CAS NO.2499-95-8)

Molecular Formula: C₉H₁₆O₂
Molecular Weight: 156.22g/mol
Mol File: 219-698-5.mol
Appearance: Clear colorless liquid
Melting Point: -45°C
Boiling point: 191.6 °C at 760 mmHg
Flash Point: 58.3 °C
Density: 0.888 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.428(lit.)
Surface Tension: 27.9 dyne/cm
Enthalpy of Vaporization: 42.78 kJ/mol
Vapour Pressure: 0.51 mmHg at 25°C
XLogP3: 3.4
H-Bond Donor: 0
H-Bond Acceptor: 2
Product Categories: AcrylateCarbonyl Compounds; Acrylic Monomers; C8 to C9; Esters; Monomers

Hexyl acrylate Toxicity Data With Reference

1.		orl-rat LD50:26 g/kg		AIHAAP American Industrial Hygiene Association Journal. 30 (1969),470.
2.		skn-rbt LD50:5660 mg/kg		AIHAAP American Industrial Hygiene Association Journal. 30 (1969),470.

Hexyl acrylate Consensus Reports

Reported in EPA TSCA Inventory.

Hexyl acrylate Safety Profile

Mildly toxic by skin contact. See also ESTERS. When heated to decomposition it emits acrid smoke and fumes.
Safety Information of Hexyl acrylate (CAS NO.2499-95-8):
Hazard Codes: Xi,N
Risk Statements: 36/37/38-43-51/53
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
43: May cause sensitization by skin contact
51: Toxic to aquatic organisms
53: May cause long-term adverse effects in the aquatic environment
Safety Statements: 24-26-37-61
24: Avoid contact with skin
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37: Wear suitable gloves
61: Avoid release to the environment. Refer to special instructions safety data sheet

Hexyl acrylate Specification

Hexyl acrylate ,its CAS NO. is 2499-95-8,the synonyms is n-Hexyl acrylate ; 2-Propenoic acid,n-hexyl ester ; 2-Propenoicacid,hexylester ; Acrylic acid, hexyl ester ; Acrylicacid,hexylester ; Ageflex fa-6 ; Ageflex n-ha ; Ageflexn-ha .

Product Name

N-HEXYL ACRYLATE

Synthetic route

Hexyl acrylate Chemical Properties

Hexyl acrylate Toxicity Data With Reference

Hexyl acrylate Consensus Reports

Hexyl acrylate Safety Profile

Hexyl acrylate Specification

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