-
Name
isoxsuprine
- EINECS 206-898-2
- CAS No. 395-28-8
- Density 1.146g/cm3
- Solubility
- Melting Point 102.5-103.5°
- Formula C18H23 N O3
- Boiling Point 484.2°Cat760mmHg
- Molecular Weight 301.386
- Flash Point 246.6°C
- Transport Information
- Appearance
- Safety Poison by ingestion, intravenous and intraperitoneal routes. A human teratogen. Human reproductive effects by ingestion: uterus, cervix and vagina effects. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. Used to delay premature parturition (labor) and to accelerate fetal lung development.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Benzylalcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (6CI,8CI);1-(p-Hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol;2-(3-Phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanol;Isoxsuprine;erythro-1-(p-Hydroxyphenyl)-2-(a-methyl-b-phenoxyethylamino)propanol;p-Hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine;p-Hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)-amino]ethyl]benzylalcohol;
- PSA 61.72000
- LogP 3.26210
Isoxsuprine Chemical Properties
IUPAC Name: 4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino)propyl]phenol
Synonyms: Lsoxsuprine ; 1-(p-Hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol ; Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (9CI) ; Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (6CI, 8CI) ; erythro-1-(p-Hydroxyphenyl)-2-(a-methyl-b-phenoxyethylamino)propanol ; p-Hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)-amino]ethyl]benzyl alcohol ; p-Hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine
EINECS: 206-898-2
Density: 1.146 g/cm3
Flash Point: 246.6 °C
Index of Refraction: 1.58
Surface Tension: 46.9 dyne/cm
Enthalpy of Vaporization: 78.94 kJ/mol
Boiling Point: 484.2 °C at 760 mmHg
Vapour Pressure: 3.45E-10 mmHg at 25°C
Molecular Formula of Isoxsuprine (CAS NO.395-28-8 ) : C18H23NO3
Molecular Weight: 301.3801 g/mol
Molecular Structure of Isoxsuprine (CAS NO.395-28-8 ) :
Isoxsuprine Toxicity Data With Reference
| 1. | orl-mus LD50:200 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1992. | ||
| 2. | ipr-mus LD50:118 mg/kg | FRPSAX Farmaco, Edizione Scientifica. 38 (1983),571. | ||
| 3. | ivn-mus LD50:48 mg/kg | EJMCA5 European Journal of Medicinal Chemistry. Chimie Therapeutique. 10 (1975),291. |
Isoxsuprine Safety Profile
Poison by ingestion, intravenous and intraperitoneal routes. A human teratogen. Human reproductive effects by ingestion: uterus, cervix and vagina effects. An experimental teratogen. Experimental reproductive effects. When heated to decomposition Isoxsuprine (CAS NO.395-28-8 ) emits toxic fumes of NOx. Used to delay premature parturition (labor) and to accelerate fetal lung development.
Isoxsuprine Specification
Classification Code of Isoxsuprine (CAS NO.395-28-8 ) : Adrenergic Agents;Adrenergic Agonists;Adrenergic beta-agonists;Autonomic Agents;Cardiovascular Agents;Human Data;Neurotransmitter Agents;Peripheral Nervous System Agents;
Reproductive Control Agents;Reproductive Effect;Sympathomimetics;Tocolytic agents;Vasodilator agents
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