-
Name
Miglitol
- EINECS 276-661-6
- CAS No. 72432-03-2
- Article Data11
- CAS DataBase
- Density 1.458 g/cm3
- Solubility Soluble
- Melting Point 114 °C
- Formula C8H17NO5
- Boiling Point 453.7 °C at 760 mmHg
- Molecular Weight 207.227
- Flash Point 284.3 °C
- Transport Information
- Appearance white to light yellow crystal powder
- Safety
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 3,4,5-Piperidinetriol,1-(2-hydroxyethyl)-2-(hydroxymethyl)-, [2R-(2a,3b,4a,5b)]-;BAY 1099;BAY-m 1099;Diastabol;Glyset;3,4,5-Piperidinetriol,1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R,3R,4R,5S)-;
- PSA 104.39000
- LogP -3.32420
Synthetic route
| Conditions | Yield |
|---|---|
| With zinc(II) chloride at 50℃; for 48h; | 90% |
Miglitol Chemical Properties
Structure of Miglitol (CAS NO.72432-03-2):
IUPAC Name: (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Empirical Formula: C8H17NO5
Molecular Weight: 207.2243
EINECS: 276-661-6
Index of Refraction: 1.597
Molar Refractivity: 48.48 cm3
Molar Volume: 142.1 cm3
Polarizability: 19.22×10-24cm3
Surface Tension: 79.2 dyne/cm
Density: 1.458 g/cm3
Flash Point: 284.3 °C
Enthalpy of Vaporization: 82.27 kJ/mol
Melting Point: 114°C
Boiling Point: 453.7 °C at 760 mmHg
Vapour Pressure: 3.87E-10 mmHg at 25°C
Water Solubility: Soluble
Physical Appearance: white to light yellow crystal powder
Product Categories: Antidiabetic;Diabetes;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Miglitol Uses
Miglitol (CAS NO.72432-03-2) is an oral anti-diabetic drug .Its acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides and polysaccharides,etc) into monosaccharides which can be absorbed by the body.
Miglitol Specification
Miglitol , its cas register number is 72432-03-2. It also can be called (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol ; 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))- ; Bay 1099 ; Bay m 1099 ; Glyset ; Miglitolum ; N-(2-Hydroxyethyl)-1-deoxynojirimycin .
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