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Luhan Pharmachem Co., Ltd

Luhan Pharmachem Co., Ltd. owns strong elite professional quality sales force, has the customer base from the US, Europe, Japan, Southeast Asia, Korea, Hong Kong, Taiwan and other countries and regions, the company operates in accordance with the mod

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Chloropropiophenone supplier in China

Cas:936-59-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply β-chloropropiophenone

Cas:936-59-4

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 936-59-4 3-Chloropropiophenone Manufacturer

Cas:936-59-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Chloropropiophenone

Cas:936-59-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 936-59-4 with best quality

Cas:936-59-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

1-Propanone,3-chloro-1-phenyl-

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Propanone,3-chloro-1-phenyl- 936-59-4

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3-Chloropropiophenone CAS: 936-59-4 MF: C9H9ClO MW: 168.62 EINECS: 213-317-6 Mol File: 936-59-4.mol 3-Chloropropiophenone Structure 3-Chloropropiophenone Chemical Properties Melting point 48-50 °C(lit.) Boili

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 3-Chloropropiophenone CAS:936-59-4

Cas:936-59-4

Min.Order:1 Kilogram

FOB Price: $42.0 / 46.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Chloropropiophenone CAS:936-59-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inter

3-Chloropropiophenone CAS:936-59-4

Cas:936-59-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:936-59-4

Cas:936-59-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 3-Chloropropiophenone Synonyms: 3-CHLORO-1-PHENYL-1-PROPANONE;3-CHLORO-1-OXO-1-PHENYLPROPANE;B-CHLOROPROPIOPHENONE;BETA-CHLOROPROPIOPHENONE;3-Chloropropiophenone98%;Chloropropiophenone, 98+%;beta-Chloropropiophenone,98+%;3-Chloropr

3-Chloropropiophenone supplier best quality

Cas:936-59-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We have two GMP facilities in Hubei Province and cooperative factories in Zhejiang Province We are concentrating on the R&D and technical service of APIs and pharmaceutical intermediates Appearance:white powder Storage:room temperature Pa

3-Chloropropiophenone

Cas:936-59-4

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Chloropropiophenone

Cas:936-59-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci

3-Chloropropiophenone CAS 936-59-4

Cas:936-59-4

Min.Order:1 Kilogram

FOB Price: $150.0 / 180.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3-Chloropropiophenone

Cas:936-59-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name:3-ChloropropiophenoneSynonyms:3-CHLORO-1-PHENYL-1-PROPANONE;3-CHLORO-1-OXO-1-PHENYLPROPANE;B-CHLOROPROPIOPHENONE;BETA-CHLOROPROPIOPHENONE;3-Chloropropiophenone98%;Chloropropiophenone, 98+%;beta-Chloropropiophenone,98+%;3-Chloro

TIANFUCHEM--936-59-4---3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Metric Ton

FOB Price: $20.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 3-Chloropropiophenone CAS No.:936-59-4 Molecule Formula:C9H9ClO Molecule Weight:168.62 Purity: 99.0% Package: 25kg/drum Description: White or light yellow crystals powder Manufacture Standards:Enterprise Standard

High Quality 3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality products. Cle

3-Chloropropiophenone99%

Cas:936-59-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

1-Propanone,3-chloro-1-phenyl-

Cas:936-59-4

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3-Chloropropiophenone

Cas:936-59-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Langyou International Trading Co., Ltd

We are a large company integrating the production and sales of chemical and pharmaceutical intermediates. Appearance:Off-White to Pale Yellow Package:1kg Application:Pharmaceutical intermediate

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

3-Chloropropiophenone

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical

3-Chloropropiophenone.

Cas:936-59-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

benzene
71-43-2

benzene

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 0 - 20℃; Inert atmosphere;100%
aluminium trichloride; nitromethane In carbon disulfide for 2h; Product distribution; Mechanism; Ambient temperature; further Friedel-Crafts catalysts, further arenes, further haloacid chlorides; variation of temperature and time;88%
aluminium trichloride; nitromethane In carbon disulfide for 2h; Ambient temperature;88%
phenylpropyl chloride
104-52-9

phenylpropyl chloride

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With Oxone; potassium bromide In dichloromethane; water at 20℃; for 24h; visible light irradiation;97%
3-chloro-1-phenyl-propan-1-ol
18776-12-0

3-chloro-1-phenyl-propan-1-ol

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid; sodium bromide In water at 60℃; for 2h; Inert atmosphere;93%
With dipotassium peroxodisulfate; V2O5/TiO2 In water; acetonitrile at 80℃; Sealed tube; Green chemistry;88%
With oxone; C18H17IN2O7PolS(1-)*Na(1+); tetra(n-butyl)ammonium hydrogensulfate In acetonitrile at 70℃; for 18h; Reagent/catalyst; Solvent; Sealed tube; Green chemistry;84%
With sodium dichromate; sulfuric acid
cinnamyl chloride
2687-12-9

cinnamyl chloride

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With iron(II) acetylacetonate; Triethoxysilane In tert-butyl alcohol at 20℃; for 24h; regioselective reaction;90%
With tris(1-phenylbutane-1,3-dionato)iron(III); phenylsilane In ethanol at 20℃; for 6.5h; Reagent/catalyst; Wacker Oxidation;81%
With iron(III) chloride; tetraphenylsilane In tert-butyl alcohol at 80℃; for 24h;90 %Chromat.
Phenyl vinyl ketone
768-03-6

Phenyl vinyl ketone

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With Triphenylphosphine oxide In dichloromethane at 20℃; for 2h;88%
With hydrogenchloride; diethyl ether
1-phenylcyclopropan-1-ol
29526-96-3

1-phenylcyclopropan-1-ol

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With manganese(II) triflate; tetrabutylammonium acetate; acetic acid; magnesium chloride In acetonitrile at 25℃; for 3.5h; Inert atmosphere; Electrochemical reaction; Sealed tube;54%
diphenyl cadmium
2674-04-6

diphenyl cadmium

2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
51%
diethyl ether
60-29-7

diethyl ether

ethyl 3-chloropropanoate
623-71-2

ethyl 3-chloropropanoate

phenylmagnesium bromide

phenylmagnesium bromide

A

3-chloropropiophenone
936-59-4

3-chloropropiophenone

B

3,3-diphenylallyl chloride
24626-27-5

3,3-diphenylallyl chloride

ethyl 3-chloropropanoate
623-71-2

ethyl 3-chloropropanoate

phenylmagnesium bromide

phenylmagnesium bromide

A

3-chloropropiophenone
936-59-4

3-chloropropiophenone

B

3,3-diphenylallyl chloride
24626-27-5

3,3-diphenylallyl chloride

Conditions
ConditionsYield
With diethyl ether Destillation des nach Hydrolyse erhaltenen Reaktionsprodukts unter vermindertem Druck;
benzoyl chloride
98-88-4

benzoyl chloride

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With ethyl bromide; aluminium trichloride anschliessendes Einleiten von Aethylen;
2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With aluminium trichloride; benzene
hydrogenchloride
7647-01-0

hydrogenchloride

acetic acid
64-19-7

acetic acid

1-phenyl-propan-1-one
93-55-0

1-phenyl-propan-1-one

A

3-chloropropiophenone
936-59-4

3-chloropropiophenone

B

2-chloro-1-phenyl-propanone-(1)

2-chloro-1-phenyl-propanone-(1)

Conditions
ConditionsYield
an Graphit-Anoden.Electrolysis;
benzene
71-43-2

benzene

β-chloro-propionic acid chloride

β-chloro-propionic acid chloride

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With aluminium trichloride
3-oxo-3-phenylpropyl(triphenyl)bismuthonium tetrafluoroborate

3-oxo-3-phenylpropyl(triphenyl)bismuthonium tetrafluoroborate

A

3-chloropropiophenone
936-59-4

3-chloropropiophenone

B

Phenyl vinyl ketone
768-03-6

Phenyl vinyl ketone

C

3-oxo-3-phenylpropyl formate

3-oxo-3-phenylpropyl formate

D

triphenylbismuthane

triphenylbismuthane

Conditions
ConditionsYield
With potassium chloride In N,N-dimethyl-formamide for 8h; Ambient temperature;A 28 % Turnov.
B 25 % Turnov.
C 25 % Turnov.
D n/a
3-chloro-1-phenyl-propan-1-ol
18776-12-0

3-chloro-1-phenyl-propan-1-ol

A

3-chloropropiophenone
936-59-4

3-chloropropiophenone

B

(1R)-3-chloro-1-phenylpropanol
100306-33-0

(1R)-3-chloro-1-phenylpropanol

Conditions
ConditionsYield
With Sphingomonas paucimobilis NCIMB 8195 In water; N,N-dimethyl-formamide for 120h;A 21 % Chromat.
B 79 % Chromat.
formaldehyd
50-00-0

formaldehyd

acetophenone
98-86-2

acetophenone

A

3-chloropropiophenone
936-59-4

3-chloropropiophenone

B

1-phenyl-3-chloro-2-(chloromethyl)-1-propanone
39192-57-9

1-phenyl-3-chloro-2-(chloromethyl)-1-propanone

C

4-chloromethylacetophenone
54589-56-9

4-chloromethylacetophenone

D

Phenyl vinyl ketone
768-03-6

Phenyl vinyl ketone

Conditions
ConditionsYield
With hydrogenchloride for 2h; Heating; Further byproducts. Title compound not separated from byproducts.;
1-phenyl-propan-1-one
93-55-0

1-phenyl-propan-1-one

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
With hydrogenchloride; ammonium nitrate; iodine; oxygen In water; acetonitrile at 60℃; for 24h; Green chemistry; regioselective reaction;
benzoic acid ethyl ester
93-89-0

benzoic acid ethyl ester

3-chloropropiophenone
936-59-4

3-chloropropiophenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: titanium(IV) isopropylate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere; Sealed tube
2: acetic acid; manganese(II) triflate; magnesium chloride; tetrabutylammonium acetate / acetonitrile / 3.5 h / 25 °C / Inert atmosphere; Electrochemical reaction; Sealed tube
View Scheme
1,2,3,4-tetrahydroisoquinoline
91-21-4

1,2,3,4-tetrahydroisoquinoline

3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone
861369-89-3

3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; for 16h;100%
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
1745-07-9

6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-phenyl-propan-1-one
773030-82-3

3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-phenyl-propan-1-one

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃;100%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

(S)-1-(p-chlorophenyl)ethylamine
4187-56-8

(S)-1-(p-chlorophenyl)ethylamine

3-[(S)-1-(4-chloro-phenyl)-ethylamino]-1-phenyl-propan-1-one
1114563-43-7

3-[(S)-1-(4-chloro-phenyl)-ethylamino]-1-phenyl-propan-1-one

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;100%
With triethylamine In tetrahydrofuran at 20℃;
3-chloropropiophenone
936-59-4

3-chloropropiophenone

Phenyl vinyl ketone
768-03-6

Phenyl vinyl ketone

Conditions
ConditionsYield
With triethylamine In chloroform at 20℃; for 18.0833h; Inert atmosphere;99%
With triethylamine In chloroform at 0 - 30℃; for 18h;99%
With triethylamine In chloroform for 18h;99%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

(1R)-3-chloro-1-phenylpropanol
100306-33-0

(1R)-3-chloro-1-phenylpropanol

Conditions
ConditionsYield
With borane; S-oxaborolidine In tetrahydrofuran at 0℃; for 0.833333h;99%
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; C22H32N4O4S2; water; sodium formate at 40℃; for 0.25h; Air atmosphere; optical yield given as %ee; enantioselective reaction;99%
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; (1R,2R)-9H-fluorene-2,7-disulfonic acid bis-[(2-amino-cyclohexyl)amide]; sodium formate In water at 40℃; for 0.25h; optical yield given as %ee; enantioselective reaction;99%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

4-tert-butylphenylboronic acid
123324-71-0

4-tert-butylphenylboronic acid

3-(4-(tert-butyl)phenyl)-1-phenylpropan-1-one
138722-46-0

3-(4-(tert-butyl)phenyl)-1-phenylpropan-1-one

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 80℃; under 750.075 Torr; for 30h; Inert atmosphere;99%
Thien-3-ylboronic acid
6165-69-1

Thien-3-ylboronic acid

3-chloropropiophenone
936-59-4

3-chloropropiophenone

1-phenyl-3-(thiophen-3-yl)propan-1-one
71778-01-3

1-phenyl-3-(thiophen-3-yl)propan-1-one

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Inert atmosphere;99%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-(benzyl(methyl)amino)-1-phenylpropan-1-one
21970-65-0

3-(benzyl(methyl)amino)-1-phenylpropan-1-one

Conditions
ConditionsYield
98%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

m-tolylboronic acid
17933-03-8

m-tolylboronic acid

1-phenyl-3-(3-methylphenyl)-1-propananone
95465-70-6

1-phenyl-3-(3-methylphenyl)-1-propananone

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Inert atmosphere;98%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

1-Naphthylboronic acid
13922-41-3

1-Naphthylboronic acid

3-(naphthalen-1-yl)-1-phenylpropan-1-one
96550-91-3

3-(naphthalen-1-yl)-1-phenylpropan-1-one

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Inert atmosphere;98%
α-naphthol
90-15-3

α-naphthol

3-chloropropiophenone
936-59-4

3-chloropropiophenone

N,N-dimethylamino-3-(naphthyl-1-oxy)-1-phenylprop-1-amine
119356-76-2

N,N-dimethylamino-3-(naphthyl-1-oxy)-1-phenylprop-1-amine

Conditions
ConditionsYield
With sodium hydroxide In N,N-dimethyl-formamide at 60 - 65℃; for 5h; Reagent/catalyst; Temperature;97.7%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-chloro-1-phenyl-propan-1-ol
18776-12-0

3-chloro-1-phenyl-propan-1-ol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran at 20℃; for 2h;97%
With sodium tetrahydroborate In methanol at 20℃; for 24h; Inert atmosphere;95%
With sodium tetrahydroborate; ethanol In tetrahydrofuran at -10 - -5℃; for 0.333333h; Inert atmosphere;95%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

allyl bromide
106-95-6

allyl bromide

1-chloro-3-phenyl-5-hexen-3-ol
143427-44-5

1-chloro-3-phenyl-5-hexen-3-ol

Conditions
ConditionsYield
With water; ammonium chloride; zinc In tetrahydrofuran Reflux;97%
With water; ammonium chloride; zinc In tetrahydrofuran Inert atmosphere;97%
With ammonium chloride; zinc In tetrahydrofuran; water for 1h; Reflux;97%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

phenylboronic acid
98-80-6

phenylboronic acid

dihydrochalcone
1083-30-3

dihydrochalcone

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Reagent/catalyst; Solvent; Temperature; Concentration; Inert atmosphere;97%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

1-phenyl-3-(4-fluorophenyl)-1-propananone
41865-46-7

1-phenyl-3-(4-fluorophenyl)-1-propananone

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Inert atmosphere;97%
α-naphthol
90-15-3

α-naphthol

3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-(naphthalen-1-yloxy)-1-phenylpropan-1-one
41198-42-9

3-(naphthalen-1-yloxy)-1-phenylpropan-1-one

Conditions
ConditionsYield
With tetrabutylammomium bromide; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane; water at 20℃; for 42h; Temperature; Solvent; Large scale;97%
Stage #1: α-naphthol With potassium hydroxide In N,N-dimethyl-formamide at 0℃; for 2h; Inert atmosphere;
Stage #2: 3-chloropropiophenone In N,N-dimethyl-formamide at 50℃; for 30h; Reagent/catalyst; Temperature; Inert atmosphere;
73.52%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

tert-butylamine
75-64-9

tert-butylamine

3-(tert-butylamino)-1-phenylpropan-1-one
2679-37-0

3-(tert-butylamino)-1-phenylpropan-1-one

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃;96%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
72824-04-5

2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1-chloro-3-phenyl-5-hexen-3-ol
143427-44-5

1-chloro-3-phenyl-5-hexen-3-ol

Conditions
ConditionsYield
With ethanol; diethylzinc In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;96%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

(4-(2-hydroxyethoxy)phenyl)(phenyl)methanone
14814-17-6

(4-(2-hydroxyethoxy)phenyl)(phenyl)methanone

ospemifene
128607-22-7

ospemifene

Conditions
ConditionsYield
With titanium tetrachloride; zinc In 2-methyltetrahydrofuran at 15 - 50℃; Product distribution / selectivity;96%
With titanium tetrachloride; zinc In 2-methyltetrahydrofuran at -10 - 80℃; for 5.5h; Inert atmosphere;
With titanium tetrachloride; zinc In tetrahydrofuran McMurry Reaction; Reflux;
With titanium tetrachloride; zinc In tetrahydrofuran for 6h; McMurry Reaction; Reflux; Inert atmosphere;
3-chloropropiophenone
936-59-4

3-chloropropiophenone

B-allenyl-1,3,2-dioxaborolane
1314099-29-0

B-allenyl-1,3,2-dioxaborolane

(S)-(+)-1-chloro-3-phenylhex-5-yn-3-ol
1314099-35-8

(S)-(+)-1-chloro-3-phenylhex-5-yn-3-ol

Conditions
ConditionsYield
Stage #1: B-allenyl-1,3,2-dioxaborolane With (S)-3,3'-dibromo-1,1'-bi-2-naphthol at 20℃; for 0.0833333h; Inert atmosphere; Neat (no solvent);
Stage #2: 3-chloropropiophenone at 72℃; for 0.75h; Inert atmosphere; Neat (no solvent); Microwave irradiation; optical yield given as %ee; enantioselective reaction;
96%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

1-phenyl-3-(2-methylphenyl)-1-propananone
84839-91-8

1-phenyl-3-(2-methylphenyl)-1-propananone

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Inert atmosphere;96%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

4-trifluoromethylphenylboronic acid
128796-39-4

4-trifluoromethylphenylboronic acid

1-phenyl-3-(4-(trifluoromethyl)phenyl)propan-1-one

1-phenyl-3-(4-(trifluoromethyl)phenyl)propan-1-one

Conditions
ConditionsYield
With potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 60℃; under 750.075 Torr; for 20h; Inert atmosphere;96%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

(S)-1-phenyl-1-propanol
613-87-6

(S)-1-phenyl-1-propanol

Conditions
ConditionsYield
With formic acid; C30H31ClN2O2RuS; triethylamine at 60℃; for 1.5h; Inert atmosphere; enantioselective reaction;96%
Multi-step reaction with 2 steps
1: sodium carbonate / water / 72 h / 28 °C / pH 9
2: yeast strain Rhodotorula glutinis H93 / Microbiological reaction
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / chloroform / Inert atmosphere
2: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; Boc-L-alanine(2S)-hydroxypropylamide; lithium chloride; potassium tert-butylate / tetrahydrofuran; ethanol / 40 °C / Inert atmosphere
View Scheme
4,4'-Dihydroxybenzophenone
611-99-4

4,4'-Dihydroxybenzophenone

3-chloropropiophenone
936-59-4

3-chloropropiophenone

4,4'-(4"-chloro-2"-phenylbut-1"-ene-1",1"-diyl)diphenol

4,4'-(4"-chloro-2"-phenylbut-1"-ene-1",1"-diyl)diphenol

Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at 0 - 20℃; for 5h; McMurry Reaction; Inert atmosphere; Reflux;96%
With titanium tetrachloride; zinc In tetrahydrofuran for 2.5h; McMurry Reaction; Inert atmosphere; Reflux;70%
With titanium tetrachloride; zinc In tetrahydrofuran McMurry Reaction;
3-chloropropiophenone
936-59-4

3-chloropropiophenone

triethyl phosphite
122-52-1

triethyl phosphite

diethyl (3-oxo-3-phenylpropyl)phosphonate
16324-15-5

diethyl (3-oxo-3-phenylpropyl)phosphonate

Conditions
ConditionsYield
for 6h; Heating;95%
With aluminum oxide for 0.0833333h; Arbuzov rearrangement; microwave irradiation;90%
at 85 - 100℃; Kinetics; Thermodynamic data; Mechanism; Ea, ΔH(excit.), ΔS(excit.), ΔG(excit.); other substituted 3-chloropropiophenones; other solvents;
With diethylene glycol dimethyl ether
3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-chloro-1-phenylpropan-1-ol

3-chloro-1-phenylpropan-1-ol

Conditions
ConditionsYield
With sodium tetrahydroborate; dimethyl sulfate; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole In tetrahydrofuran at 0℃; for 1.5h; Inert atmosphere; enantioselective reaction;95%
2-[(1,3,2-dioxaborolan-2-yloxy)diphenylmethyl]pyrrolidine Product distribution / selectivity;86%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

B-allyl-1,3,2-dioxaborinane
54655-41-3

B-allyl-1,3,2-dioxaborinane

(R)-(-)-1-chloro-3-phenylhex-5-en-3-ol

(R)-(-)-1-chloro-3-phenylhex-5-en-3-ol

Conditions
ConditionsYield
With (S)-3,3'-dibromo-1,1'-bi-2-naphthol; tert-butyl alcohol at 20℃; for 24h; Inert atmosphere; enantioselective reaction;95%
3-chloropropiophenone
936-59-4

3-chloropropiophenone

3-Chloro-2-methylpropene
563-47-3

3-Chloro-2-methylpropene

1-chloro-5-methyl-3-phenylhex-5-en-3-ol
1110641-65-0

1-chloro-5-methyl-3-phenylhex-5-en-3-ol

Conditions
ConditionsYield
Stage #1: 3-Chloro-2-methylpropene With diisobutylaluminium hydride; magnesium In tetrahydrofuran; hexane at 20 - 30℃; for 2h; Inert atmosphere;
Stage #2: With cerium(III) chloride In tetrahydrofuran; hexane at -10℃; for 0.5h; Inert atmosphere;
Stage #3: 3-chloropropiophenone
95%
Stage #1: 3-Chloro-2-methylpropene With diisobutylaluminium hydride; magnesium at 20 - 30℃; for 2h; Inert atmosphere;
Stage #2: 3-chloropropiophenone With cerium(III) chloride In tetrahydrofuran; hexane at -10 - 0℃; for 1h;
Stage #3: With hydrogenchloride In tetrahydrofuran; hexane; water at 30℃;
95%
Stage #1: 3-Chloro-2-methylpropene With diisobutylaluminium hydride; magnesium In tetrahydrofuran; hexane at 20 - 30℃; Inert atmosphere;
Stage #2: With cerium(III) chloride In tetrahydrofuran; hexane at -10 - 20℃; Inert atmosphere;
Stage #3: 3-chloropropiophenone
Stage #1: 3-Chloro-2-methylpropene With diisobutylaluminium hydride; magnesium In tetrahydrofuran; hexane at 20 - 30℃; Inert atmosphere;
Stage #2: With cerium(III) chloride In tetrahydrofuran; hexane at -10 - 20℃; Inert atmosphere;
Stage #3: 3-chloropropiophenone In tetrahydrofuran; hexane at -10 - 0℃;
Stage #1: 3-Chloro-2-methylpropene With diisobutylaluminium hydride; magnesium In tetrahydrofuran; hexane at 20 - 30℃; for 2h; Inert atmosphere;
Stage #2: 3-chloropropiophenone With cerium(III) chloride In tetrahydrofuran; hexane at 0℃; for 0.5h; Inert atmosphere;
Stage #3: With hydrogenchloride; water In tetrahydrofuran; hexane at 30℃;
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