RIBOFLAVIN-ADENINE DINUCLEOTIDE supplier

Name
FLAVIN ADENINE DINUCLEOTIDE
EINECS 282-733-8
CAS No. 146-14-5
Article Data18
CAS DataBase
Density 2.08g/cm³
Solubility

Stability

Stable. Incompatible with strong oxidizing agents.

Toxicology

Not hazardous according to Directive 67/548/EEC.

Toxicity data
(The meaning of any abbre

Melting Point
Formula C27H33 N9 O15 P2
Boiling Point °Cat760mmHg
Molecular Weight 785.558
Flash Point °C
Transport Information
Appearance solid
Safety Moderately toxic by intravenous route. When heated to decomposition it emits toxic vapors of NO_x and PO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Adenosine5'-(trihydrogen pyrophosphate), 5'®5'-ester with riboflavine (8CI); Benzo[g]pteridine, riboflavin5'-(trihydrogen diphosphate) deriv.; Riboflavine, 5'-ester with adenosine5'-diphosphate (8CI); Adenine-flavin dinucleotide; Adenine-flavinedinucleotide; Adenine-riboflavin dinucleotide; Adenine-riboflavinedinucleotide; FAD; Fademin; Flavin-adenine dinucleotide; Flavinat; Flavineadenosine diphosphate; Flavine-adenine dinucleotide; Flavitan; NSC 112207;Riboflavin 5'-adenosine diphosphate; Riboflavin-adenine dinucleotide;Riboflavine-adenine dinucleotide
PSA 382.55000
LogP -1.79440

Synthetic route

: O5'-benzyloxyphosphinoyl-O2',O3'-isopropylidene-adenosine

: 146-14-5
flavin adenine dinucleotide

Conditions

Conditions	Yield
With N-chloro-succinimide; acetonitrile beim Erwaermen des Reaktionsgemisches mit dem Monothallium(I)-Salz des O5'-Phosphono-riboflavins und Triaethylamin in Phenol und Behandeln des Reaktionsprodukts mit wss. HCl;

: 146-17-8
Flavin mononucleotide

: 56-65-5
ATP

: 146-14-5
flavin adenine dinucleotide

Conditions

Conditions	Yield
With FMN-adenyltransferase
bei der Einwirkung eines Enzyms aus Rattenleber;

: 61-19-8
5'-adenosine monophosphate

monosodium-salt of O5'-phosphono-riboflavin: monosodium-salt of O5'-phosphono-riboflavin

: 146-14-5
flavin adenine dinucleotide

Conditions

Conditions	Yield
With pyridine; di-p-tolylcarbodiimide
With trifluoroacetic anhydride

N,N'-dicyclohexyl-guanidine salt of O5'--adenosine: N,N'-dicyclohexyl-guanidine salt of O5'--adenosine

pyridine salt of O5'-phosphono-riboflavin: pyridine salt of O5'-phosphono-riboflavin

: 146-14-5
flavin adenine dinucleotide

Conditions

Conditions	Yield
With pyridine; 2-monochlorophenol beim Behandeln unter Lichtausschluss;

: 1910-41-4
flavin adenine dinucleotide fully reduced neutral

: 146-14-5
flavin adenine dinucleotide

Conditions

Conditions	Yield
With Artemisone In acetonitrile
With 4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]thiomorpholine 1,1-dioxide In acetonitrile at 22℃; pH=7.4; Reagent/catalyst; Inert atmosphere;

: 61-54-1
tryptamine

: 146-14-5
flavin adenine dinucleotide

: C27H33N9O15P2*C10H12N2

Conditions

Conditions	Yield
In water Equilibrium constant; Thermodynamic data; complex formation, -ΔG, -ΔH, -ΔS;

: 50-67-9
3-(2-aminoethyl)-1H-indol-5-ol

: 146-14-5
flavin adenine dinucleotide

: C27H33N9O15P2*C10H12N2O

Conditions

Conditions	Yield
In water Equilibrium constant; Thermodynamic data; complex formation, -ΔG, -ΔH, -ΔS;

: 146-14-5
flavin adenine dinucleotide

: 73-22-3
L-Tryptophan

: C27H33N9O15P2*C11H12N2O2

Conditions

Conditions	Yield
In water Equilibrium constant; Thermodynamic data; complex formation, -ΔG, -ΔH, -ΔS;

: 146-14-5
flavin adenine dinucleotide

: 1910-41-4
flavin adenine dinucleotide fully reduced neutral

Conditions

Conditions	Yield
With phosphate buffer; hydrogen; Na2 anchored onto OAE-SEPHADEX anion exchanger at 20℃; for 1.66667h;
With Escherichia coli flavin reductase; NADPH at 22℃; pH=7.4; Inert atmosphere; aq. buffer; Enzymatic reaction;
With NAD(P)H:flavin oxidoreductase E. coli flavin reductase; NADH In aq. buffer at 22℃; for 0.000833333h; pH=7.4; Inert atmosphere; Enzymatic reaction;

: 7732-18-5
water

: 146-14-5
flavin adenine dinucleotide

: 1088-56-8
lumiflavin

Conditions

Conditions	Yield
at 20℃; pH 7-14.Photolysis;

: 146-14-5
flavin adenine dinucleotide

aqueous NaOH: aqueous NaOH

: 1088-56-8
lumiflavin

Conditions

Conditions	Yield
at 0 - 80℃; Photolysis;

: 7647-01-0
hydrogenchloride

: 146-14-5
flavin adenine dinucleotide

A: 1088-56-8
lumiflavin

B: 61-19-8
5'-adenosine monophosphate

C: 146-17-8
Flavin mononucleotide

D: 83-88-5
riboflavin

Conditions

Conditions	Yield
Adenin, O5-Phosphono-D-ribose und H3PO4;

...Expand

: 7732-18-5
water

: 146-14-5
flavin adenine dinucleotide

A: 1088-56-8
lumiflavin

B: 61-19-8
5'-adenosine monophosphate

C: 146-17-8
Flavin mononucleotide

D: 83-88-5
riboflavin

Conditions

Conditions	Yield
vom pH 3-9;
bei der Einwirkung von Sonnenlicht;

...Expand

: 902-04-5
2'-deoxyguanosine 5'-monophosphate

: 146-14-5
flavin adenine dinucleotide

: C27H34N9O15P2

Conditions

Conditions	Yield
In phosphate buffer pH=7; Kinetics; UV-irradiation;

: 79-24-3
Nitroethane

: 143-33-9
sodium cyanide

: 146-14-5
flavin adenine dinucleotide

: C30H38N10O15P2

Conditions

Conditions	Yield
With recombinant nitroalkane oxidase; oxygen In water at 30℃; pH=8.0; Kinetics;

...Expand

: 646-14-0
1-nitrohexane

: 143-33-9
sodium cyanide

: 146-14-5
flavin adenine dinucleotide

: C34H46N10O15P2

Conditions

Conditions	Yield
With recombinant nitroalkane oxidase; oxygen In water at 4℃; for 0.0833333h;

...Expand

: silver nitrate

: 146-14-5
flavin adenine dinucleotide

: {Ag(CH3)2C2(CH)2C2NNHC2NC(O)NC(O)}(1+)

Conditions

Conditions	Yield
With NaOH In water addn. of 10-fold molar exess of AgNO3 to aq. soln. of flavin, cooling to 0°C, stirring (subdued light), adjustment of pH to 6.3 (NaOH, dropwise);

: 146-14-5
flavin adenine dinucleotide

: 4250-90-2
Formylmethylflavin

Conditions

Conditions	Yield
Stage #1: flavin adenine dinucleotide for 0.0833333h; UV-irradiation; Stage #2: With oxygen

: 146-14-5
flavin adenine dinucleotide

: 1262230-71-6
C27H33N9O15P2(1-)

Conditions

Conditions	Yield
In water pH=7.4; Quantum yield; pH-value; Inert atmosphere; UV-irradiation;

: 146-14-5
flavin adenine dinucleotide

A: 1262230-71-6
C27H33N9O15P2(1-)

B: C27H34N9O15P2

Conditions

Conditions	Yield
With lysozyme from egg white In water pH=7.4; Quantum yield; Reagent/catalyst; pH-value; Inert atmosphere; UV-irradiation;

: 816-66-0
4-methyl-2-oxopentanoic acid

: 146-14-5
flavin adenine dinucleotide

: C32H43N9O16P2

Conditions

Conditions	Yield
With ethylenediaminetetraacetic acid; D-arginine dehydrogenase Irradiation;

{3′-d(AGAAAGTTTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}: {3′-d(AGAAAGTTTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}

: 146-14-5
flavin adenine dinucleotide

flavin adenine dinucleotide bound {3′-d(AGAAAGTTTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}: flavin adenine dinucleotide bound {3′-d(AGAAAGTTTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}

Conditions

Conditions	Yield
With sodium chloride In aq. phosphate buffer pH=6;

{3′-d(AGAAAGTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}: {3′-d(AGAAAGTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}

: 146-14-5
flavin adenine dinucleotide

flavin adenine dinucleotide bound {3′-d(AGAAAGTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}: flavin adenine dinucleotide bound {3′-d(AGAAAGTTTTAGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}

Conditions

Conditions	Yield
With sodium chloride In aq. phosphate buffer pH=6;

{3′-d(AGAAAG(HEG)AGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}: {3′-d(AGAAAG(HEG)AGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}

: 146-14-5
flavin adenine dinucleotide

flavin adenine dinucleotide bound {3′-d(AGAAAG(HEG)AGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}: flavin adenine dinucleotide bound {3′-d(AGAAAG(HEG)AGAGAA)-5′}*{3′-d(TTCTCTTCTTTCTTTTTTTCTTTCTTCTCTT)-5′}

Conditions

Conditions	Yield
With sodium chloride In aq. phosphate buffer pH=6;

RIBOFLAVIN-ADENINE DINUCLEOTIDE Chemical Properties

MF: C₂₇H₃₃N₉O₁₅P₂
MW: 785.55
EINECS: 282-733-8
Storage temp: −20°C
Appearance: orange powder
Index of Refraction: 1.85
IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
Product Categories: Substrates ; Biochemistry ; Vitamin Derivatives ; Vitamins
Stability: Stable. Incompatible with strong oxidizing agents.
Solubility: soluble in water, insoluble in ethanol, aqueous solution was yellow-green fluorescence, the event of alkali decomposition of riboflavin
Synonyms: Flavine adenine dinucleotide ; Flavine-adenine dinucleotide ; Adenine-flavindinucleotide ; Adenine-flavinedinucleotide ; Adenine-riboflavindinuceotide ; Adenine-riboflavindinucleotide ; Adenosine5’-(trihydrogenpyrophosphate),5’-5’-esterwithriboflavine ; Flavinadenindinucleotide
Following is the molecular structure of Riboflavin-adenine dinucleotide (146-14-5):

RIBOFLAVIN-ADENINE DINUCLEOTIDE Uses

Riboflavin-adenine dinucleotide (146-14-5) is use for mucocutaneous disease, nervous tinnitus, cerebral arteriosclerosis, intractable headache, liver cirrhosis, jaundice and other liver diseases, eye diseases, retinal disorders. Rapid intravenous injection of chest discomfort can be seen temporarily.

RIBOFLAVIN-ADENINE DINUCLEOTIDE Toxicity Data With Reference

ivn-mus LD50:700 mg/kg

DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),689.

RIBOFLAVIN-ADENINE DINUCLEOTIDE Consensus Reports

Reported in EPA TSCA Inventory.

RIBOFLAVIN-ADENINE DINUCLEOTIDE Safety Profile

Moderately toxic by intravenous route. When heated to decomposition it emits toxic vapors of NO_x and PO_x.
Safety Information of Riboflavin-adenine dinucleotide (146-14-5):
WGK Germany: 3
RTECS: AU7470000

Product Name

FLAVIN ADENINE DINUCLEOTIDE

Stability

Toxicology

Synthetic route

RIBOFLAVIN-ADENINE DINUCLEOTIDE Chemical Properties

RIBOFLAVIN-ADENINE DINUCLEOTIDE Uses

RIBOFLAVIN-ADENINE DINUCLEOTIDE Toxicity Data With Reference

RIBOFLAVIN-ADENINE DINUCLEOTIDE Consensus Reports

RIBOFLAVIN-ADENINE DINUCLEOTIDE Safety Profile

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