Product Name

  • Name

    Triphenylmethyl chloride

  • EINECS 200-986-4
  • CAS No. 76-83-5
  • Article Data132
  • CAS DataBase
  • Density 1.141 g/cm3
  • Solubility chloroform: 0.1 g/mL
  • Melting Point 109-112 °C
  • Formula C19H15Cl
  • Boiling Point 374.3 °C at 760 mmHg
  • Molecular Weight 278.781
  • Flash Point 177.9 °C
  • Transport Information UN 3261 8/PG 3
  • Appearance white to yellow solid
  • Safety 26-36/37/39-45-61-27
  • Risk Codes 34-50/53-14-36/37
  • Molecular Structure Molecular Structure of 76-83-5 (Triphenylmethyl chloride)
  • Hazard Symbols CorrosiveC,DangerousN
  • Synonyms Methane,chlorotriphenyl- (8CI);1,1',1''-(Chloromethylidyne)tris[benzene];Chlorotriphenylmethane;
  • PSA 0.00000
  • LogP 5.21730

Synthetic route

triphenylmethyl alcohol
76-84-6

triphenylmethyl alcohol

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With Vilsmeier reagent In 1,4-dioxane at 80℃; for 0.5h;100%
With hydrogenchloride; calcium chloride In water; toluene at 25℃; for 5h; Solvent; Reagent/catalyst;96%
With chloro-trimethyl-silane In dichloromethane; water at 0℃; for 0.666667h;90%
triphenylmethane
519-73-3

triphenylmethane

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With tetrachloromethane at 250℃; for 7h; Inert atmosphere; Autoclave;99%
With dihydrogen peroxide; lithium chloride In benzene at 50℃; for 5h; Irradiation;99.4%
With 2,2'-azobis(isobutyronitrile); benzyl(trimethyl)ammonium tetrachloroiodate In tetrachloromethane for 1h; Heating;90%
tetrachloromethane
56-23-5

tetrachloromethane

triphenylmethane
519-73-3

triphenylmethane

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
at 250℃; under 52505.3 Torr; for 7h; Inert atmosphere;99%
Triphenylmethylethylether
968-39-8

Triphenylmethylethylether

acetyl chloride
75-36-5

acetyl chloride

A

trityl chloride
76-83-5

trityl chloride

B

ethyl acetate
141-78-6

ethyl acetate

Conditions
ConditionsYield
at 13℃; for 70h;A 97%
B 82%
at 70℃; for 13h;A 4.68 g
B 1.25 g
methoxytriphenylmethane
596-31-6

methoxytriphenylmethane

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With thionyl chloride In n-heptane 1.) RT, 10 min, 2.) reflux, 1 d;96%
Triphenylmethylethylether
968-39-8

Triphenylmethylethylether

benzoyl chloride
98-88-4

benzoyl chloride

A

benzoic acid ethyl ester
93-89-0

benzoic acid ethyl ester

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
at 70 - 100℃; for 35h;A 78%
B 86%
at 70 - 100℃; for 35h;A 0.81 g
B 1.64 g
tritylsulfenyl chloride
24165-03-5

tritylsulfenyl chloride

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With 1H-imidazole; triethylamine In dichloromethane at 20℃; for 1h;83%
Heating;
tetrachloromethane
56-23-5

tetrachloromethane

benzene
71-43-2

benzene

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With iron(III) chloride at 15 - 150℃; under 2625.26 - 4500.45 Torr; for 5h; Temperature; Pressure; Autoclave;82%
Stage #1: tetrachloromethane With aluminum (III) chloride In Petroleum ether at 120 - 150℃; for 1h;
Stage #2: benzene In Petroleum ether at 60℃; under 760.051 Torr; for 0.5h; Reagent/catalyst; Solvent; Temperature; Pressure; Microwave irradiation;
80.1%
With iron(III) chloride
norborn-2-ene
498-66-8

norborn-2-ene

tritylsulfenyl chloride
24165-03-5

tritylsulfenyl chloride

A

trityl chloride
76-83-5

trityl chloride

endo-2-chloro-exo-1-(triphenylmethyldithio)bicyclo<2.2.1>heptane
80345-24-0

endo-2-chloro-exo-1-(triphenylmethyldithio)bicyclo<2.2.1>heptane

Conditions
ConditionsYield
Ambient temperature;A n/a
B 82%
benzyl trityl ether
5333-62-0

benzyl trityl ether

A

trityl chloride
76-83-5

trityl chloride

B

benzyl alcohol
100-51-6

benzyl alcohol

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 27h; Reflux;A n/a
B 81%
stearyl trityl ether

stearyl trityl ether

A

1-octadecanol
112-92-5

1-octadecanol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 35h; Reagent/catalyst; Solvent; Temperature; Reflux;A 80%
B 65%
cyclopentyl trityl ether
1241-40-3

cyclopentyl trityl ether

A

Cyclopentanol
96-41-3

Cyclopentanol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 31h; Reflux;A 75%
B n/a
(decyloxymethanetriyl)tribenzene
500288-61-9

(decyloxymethanetriyl)tribenzene

A

1-Decanol
112-30-1

1-Decanol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 28h; Reflux;A 71%
B n/a
hexyl trityl ether
85058-11-3

hexyl trityl ether

A

trityl chloride
76-83-5

trityl chloride

B

hexan-1-ol
111-27-3

hexan-1-ol

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 30h; Reflux;A n/a
B 70%
(cyclohexyloxy)triphenylmethane
20705-40-2

(cyclohexyloxy)triphenylmethane

A

trityl chloride
76-83-5

trityl chloride

B

cyclohexanol
108-93-0

cyclohexanol

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 31h; Reflux;A n/a
B 70%
trans-2-chloro-1-(triphenylmethyldithio)cyclohexane

trans-2-chloro-1-(triphenylmethyldithio)cyclohexane

A

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

B

trityl chloride
76-83-5

trityl chloride

C

C12H20Cl2S4

C12H20Cl2S4

Conditions
ConditionsYield
In ethyl acetate for 13h; Heating;A 26%
B 23%
C 69%
endo-2-chloro-exo-1-(triphenylmethyldithio)bicyclo<2.2.1>heptane
80345-24-0

endo-2-chloro-exo-1-(triphenylmethyldithio)bicyclo<2.2.1>heptane

A

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

B

trityl chloride
76-83-5

trityl chloride

C

di<(2-chloro)-1-norbornyl>tetrasulfide

di<(2-chloro)-1-norbornyl>tetrasulfide

Conditions
ConditionsYield
In ethyl acetate for 40h; Heating;A 21%
B 19%
C 68%
2-trityloxyoctane

2-trityloxyoctane

A

rac-octan-2-ol
4128-31-8

rac-octan-2-ol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 32h; Reflux;A 68%
B n/a
trityl phenoxide
5447-80-3

trityl phenoxide

A

trityl chloride
76-83-5

trityl chloride

B

phenol
108-95-2

phenol

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 25h; Reflux;A n/a
B 68%
trans-2-chloro-1-(triphenylmethyltrithio)cyclopentane

trans-2-chloro-1-(triphenylmethyltrithio)cyclopentane

A

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

B

trityl chloride
76-83-5

trityl chloride

C

C10H16Cl2S4

C10H16Cl2S4

Conditions
ConditionsYield
In ethyl acetate for 10h; Heating;A 27%
B 19%
C 67%
trans-2-chloro-1-(triphenylmethyldithio)cyclopentane

trans-2-chloro-1-(triphenylmethyldithio)cyclopentane

A

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

B

trityl chloride
76-83-5

trityl chloride

C

C10H16Cl2S4

C10H16Cl2S4

Conditions
ConditionsYield
In ethyl acetate for 8h; Heating;A 24%
B 20%
C 65%
trans-2-chloro-1-(triphenylmethyltrithio)cyclohexane

trans-2-chloro-1-(triphenylmethyltrithio)cyclohexane

A

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

B

trityl chloride
76-83-5

trityl chloride

C

C12H20Cl2S4

C12H20Cl2S4

Conditions
ConditionsYield
In ethyl acetate for 15h; Heating;A 28%
B 21%
C 65%
isoamyl trityl ether
62761-69-7

isoamyl trityl ether

A

i-Amyl alcohol
123-51-3

i-Amyl alcohol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 30h; Reflux;A 62%
B n/a
(2E)-3,7-dimethyl-1-triphenylmethoxy-2,6-octadiene
92464-82-9

(2E)-3,7-dimethyl-1-triphenylmethoxy-2,6-octadiene

A

Geraniol
106-24-1

Geraniol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 30h; Reflux;A 62%
B n/a
endo-2-chloro-exo-1-(triphenylmethyldithio)bicyclo<2.2.2>octane

endo-2-chloro-exo-1-(triphenylmethyldithio)bicyclo<2.2.2>octane

A

triphenylmethanethiol
3695-77-0

triphenylmethanethiol

B

trityl chloride
76-83-5

trityl chloride

C

C16H24Cl2S4

C16H24Cl2S4

Conditions
ConditionsYield
In ethyl acetate for 42h; Heating;A 25%
B 21%
C 60%
1,6-bis(trityloxy)hexane

1,6-bis(trityloxy)hexane

A

1,6-hexanediol
629-11-8

1,6-hexanediol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 34h; Reflux;A 60%
B n/a
1,4-di(trityloxy)pentane

1,4-di(trityloxy)pentane

A

1,4-Pentanediol
626-95-9

1,4-Pentanediol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 30h; Reflux;A 58%
B n/a
triphenylacetic acid
595-91-5

triphenylacetic acid

tungsten(VI) chloride
13283-01-7

tungsten(VI) chloride

A

carbon monoxide
201230-82-2

carbon monoxide

B

C19H15(1+)*Cl5OW(1-)

C19H15(1+)*Cl5OW(1-)

C

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
In dichloromethane at 20℃; for 18h; Inert atmosphere; Schlenk technique;A 57%
B 32%
C n/a
1,4-pentanediol monotrityl ether
74500-56-4, 104784-02-3, 104871-06-9, 78666-39-4

1,4-pentanediol monotrityl ether

A

1,4-Pentanediol
626-95-9

1,4-Pentanediol

B

trityl chloride
76-83-5

trityl chloride

Conditions
ConditionsYield
With indium; ammonium chloride In methanol for 28h; Reflux;A 56%
B n/a
TREHALOSE
99-20-7

TREHALOSE

trityl chloride
76-83-5

trityl chloride

6-O-(triphenylmethyl)-α-D-glucopyranosyl-6'-O-(triphenylmethyl)-α-D-glucopyranoside
50705-44-7, 108811-30-9

6-O-(triphenylmethyl)-α-D-glucopyranosyl-6'-O-(triphenylmethyl)-α-D-glucopyranoside

Conditions
ConditionsYield
With pyridine at 20 - 40℃; for 20h; Inert atmosphere;100%
In pyridine88%
With pyridine at 40℃; for 36h;83%
D-sorbitol
50-70-4

D-sorbitol

trityl chloride
76-83-5

trityl chloride

1,6-di-O-trityl-D-glucitol
29780-95-8

1,6-di-O-trityl-D-glucitol

Conditions
ConditionsYield
With pyridine; dmap for 48h; Ambient temperature;100%
With pyridine; dmap at 20℃; for 48h;100%
With pyridine for 1.5h; Reflux;93%
batyl alcohol
544-62-7

batyl alcohol

trityl chloride
76-83-5

trityl chloride

1-octadecyloxy-3-trityloxy-propan-2-ol
86334-56-7

1-octadecyloxy-3-trityloxy-propan-2-ol

Conditions
ConditionsYield
With pyridine for 48h; Ambient temperature;100%
With pyridine at 70℃; for 24h;96%
With pyridine
1-Hydroxy-3-butanone
590-90-9

1-Hydroxy-3-butanone

trityl chloride
76-83-5

trityl chloride

4-(trityloxy)butan-2-one
800380-59-0

4-(trityloxy)butan-2-one

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 2h;100%
With pyridine
With pyridine
trityl chloride
76-83-5

trityl chloride

propargyl alcohol
107-19-7

propargyl alcohol

1-trityloxy-2-propyne
82816-38-4

1-trityloxy-2-propyne

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane at 20℃; for 16h;100%
With pyridine; dmap In dichloromethane at 20℃; for 18h;95%
With triethylamine In dichloromethane Ambient temperature;94%
trityl chloride
76-83-5

trityl chloride

aniline
62-53-3

aniline

Phenyl-trityl-amine
4471-22-1

Phenyl-trityl-amine

Conditions
ConditionsYield
Stage #1: trityl chloride; aniline at 190℃; for 0.5h;
Stage #2: With hydrogenchloride In methanol for 0.5h; Reflux;
100%
at 50℃; for 1.5h;63%
With pyridine at 20℃; for 24h; Substitution;44%
trityl chloride
76-83-5

trityl chloride

triphenylmethyl alcohol
76-84-6

triphenylmethyl alcohol

Conditions
ConditionsYield
With water In tetrachloromethane100%
With water Kinetics; Rate constant; Mechanism; Two-phase systems;
With water In acetone at 25℃; Kinetics; ΔS, ΔH (excit.);
trityl chloride
76-83-5

trityl chloride

1,2-O-isopropylidene-α-D-xylose
20031-21-4

1,2-O-isopropylidene-α-D-xylose

1,2-O-isopropylidene-5-O-trityl-α-D-xylofuranose
20590-53-8

1,2-O-isopropylidene-5-O-trityl-α-D-xylofuranose

Conditions
ConditionsYield
With pyridine at 20℃; for 12h;100%
With pyridine for 16h;95%
With triethylamine In dichloromethane for 3h; Inert atmosphere;95%
trityl chloride
76-83-5

trityl chloride

methyl-alpha-D-glucopyranoside
97-30-3

methyl-alpha-D-glucopyranoside

methyl 6-O-trityl-α-D-glucopyranoside
18311-26-7

methyl 6-O-trityl-α-D-glucopyranoside

Conditions
ConditionsYield
With pyridine at 70℃; for 2h;100%
With pyridine at 90℃; for 72h; Inert atmosphere; Schlenk technique;100%
With 1,4-diaza-bicyclo[2.2.2]octane In dichloromethane at 30℃; for 3.5h; regioselective reaction;98%
3-(hexadecyloxy)-1,2-propanediol
6145-69-3

3-(hexadecyloxy)-1,2-propanediol

trityl chloride
76-83-5

trityl chloride

1-O-hexadecyl-3-O-trityl-rac-glycerol
82002-20-8

1-O-hexadecyl-3-O-trityl-rac-glycerol

Conditions
ConditionsYield
100%
With pyridine Ambient temperature;68%
In hexane Heating;56%
rac-1-monopalmitoylglycerol
305847-08-9

rac-1-monopalmitoylglycerol

trityl chloride
76-83-5

trityl chloride

1-palmitoyl-3-O-trityl-rac-glycerol
69256-58-2

1-palmitoyl-3-O-trityl-rac-glycerol

Conditions
ConditionsYield
With pyridine at 60℃; for 3h;100%
With pyridine at 60℃; for 3h;100%
With pyridine In chloroform
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride
5680-80-8

methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

trityl chloride
76-83-5

trityl chloride

methyl N-trityl-L-serinate
13515-76-9, 116457-91-1, 4465-44-5

methyl N-trityl-L-serinate

Conditions
ConditionsYield
With TEA In dichloromethane at 0℃; for 24h;100%
With triethylamine In dichloromethane at 0 - 20℃;98%
With triethylamine In dichloromethane at 0 - 20℃;98%
tetrahydrofuran
109-99-9

tetrahydrofuran

trityl chloride
76-83-5

trityl chloride

(C6H5)3CCaCl*2C4H8O
13889-83-3, 13973-77-8

(C6H5)3CCaCl*2C4H8O

Conditions
ConditionsYield
With calcium for 0.5h;100%
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

trityl chloride
76-83-5

trityl chloride

N-triphenylmethyl-4-hydroxypiperidine
227100-23-4

N-triphenylmethyl-4-hydroxypiperidine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃;100%
With triethylamine In dichloromethane at 20℃; for 14h;82%
With triethylamine In dichloromethane at 0℃; for 1h;
With potassium carbonate In N-methyl-acetamide
ethyl 6-aminopicolinate
69142-64-9

ethyl 6-aminopicolinate

trityl chloride
76-83-5

trityl chloride

Ethyl 6-tritylaminopicolinate
153140-21-7

Ethyl 6-tritylaminopicolinate

Conditions
ConditionsYield
With triethylamine In chloroform for 5h; Ambient temperature;100%
With triethylamine In chloroform at 20℃;
5-(4-methoxyphenyl)-1H-tetrazole
6926-51-8

5-(4-methoxyphenyl)-1H-tetrazole

trityl chloride
76-83-5

trityl chloride

5-(4-Methoxy-phenyl)-1-trityl-1H-tetrazole
137898-60-3

5-(4-Methoxy-phenyl)-1-trityl-1H-tetrazole

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 70℃; for 3h;100%
(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
32233-40-2

(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

trityl chloride
76-83-5

trityl chloride

(-)-7α-hydroxy-6β-triphenylmethoxymethyl-cis-2-oxabicyclo<3.3.0>octan-3-one
62939-85-9

(-)-7α-hydroxy-6β-triphenylmethoxymethyl-cis-2-oxabicyclo<3.3.0>octan-3-one

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 4h; Inert atmosphere;100%
With pyridine In dichloromethane93%
With pyridine at 20℃; for 48h;87%
In pyridine at 20℃; for 48h; Substitution;87%
With pyridine at 20℃; for 12h; Temperature; Large scale;
(S)-Ethyl lactate
687-47-8

(S)-Ethyl lactate

trityl chloride
76-83-5

trityl chloride

ethyl (S)-2-(trityloxy)propionate
123077-62-3

ethyl (S)-2-(trityloxy)propionate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane for 48h;100%
Stage #1: (S)-Ethyl lactate; trityl chloride With zinc(II) chloride In acetonitrile at 20℃; for 0.0833333h;
Stage #2: With triethylamine In acetonitrile at 20℃; for 0.166667h;
Stage #3: With citric acid In water; acetonitrile at 20℃; for 0.0833333h; pH=5;
83%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 48h; Inert atmosphere;82%
D-2-deoxyglucose
154-17-6

D-2-deoxyglucose

trityl chloride
76-83-5

trityl chloride

(3R,4S,5R)-3,4,5-Trihydroxy-6-trityloxy-hexanal
84457-54-5

(3R,4S,5R)-3,4,5-Trihydroxy-6-trityloxy-hexanal

Conditions
ConditionsYield
With pyridine for 15h; Ambient temperature;100%
trityl chloride
76-83-5

trityl chloride

5-exo-<(trityloxy)methyl>bicyclo<2.2.1>hept-2-ene

5-exo-<(trityloxy)methyl>bicyclo<2.2.1>hept-2-ene

Conditions
ConditionsYield
With pyridine; tetrabutylammonium perchlorate In dichloromethane for 4.5h; Ambient temperature;100%
2-azido-sphingosine
103348-49-8

2-azido-sphingosine

trityl chloride
76-83-5

trityl chloride

(2S,3R,4E)-2-azido-1-(triphenylmethyl)-4-octadecene-1,3-diol
108283-57-4

(2S,3R,4E)-2-azido-1-(triphenylmethyl)-4-octadecene-1,3-diol

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 23h;100%
With N-ethyl-N,N-diisopropylamine In dichloromethane for 26h;91%
In tetrahydrofuran; pyridine; chloroform for 48h; Ambient temperature;90%
L-threonine methyl ester hydrochloride
39994-75-7

L-threonine methyl ester hydrochloride

trityl chloride
76-83-5

trityl chloride

methyl (2S,3R)-3-hydroxy-2-triphenylmethylaminobutanoate
74481-55-3

methyl (2S,3R)-3-hydroxy-2-triphenylmethylaminobutanoate

Conditions
ConditionsYield
With triethylamine In chloroform at 0℃; for 24h;100%
With triethylamine In chloroform at 0℃; for 20h;100%
With triethylamine In chloroform at 0℃; for 72h;91%
With triethylamine In dichloromethane at 20℃; for 19h;
Conditions
ConditionsYield
With pyridine for 48h; Ambient temperature;100%
trityl chloride
76-83-5

trityl chloride

ethylenediamine
107-15-3

ethylenediamine

N-tritylethylene-1,2-diamine
75257-79-3

N-tritylethylene-1,2-diamine

Conditions
ConditionsYield
With potassium carbonate In dichloromethane100%
With potassium carbonate In dichloromethane at 20℃; for 4h; Inert atmosphere;90%
With triethylamine In dichloromethane at 20℃;83.3%
trityl chloride
76-83-5

trityl chloride

2H-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino<2,1-a><2>benzazepine
98123-61-6

2H-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino<2,1-a><2>benzazepine

2-(triphenylmethyl)-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino<2,1-a><2>benzazepine
121654-85-1

2-(triphenylmethyl)-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino<2,1-a><2>benzazepine

Conditions
ConditionsYield
With triethylamine In chloroform 1) 0 deg C, 30 min, 2) r.t., 90 min;100%
With triethylamine In chloroform100%
trityl chloride
76-83-5

trityl chloride

ethyl 2-(<2-(14)C>-2-aminothiazol-4-yl)-2-syn-methoximinoacetate

ethyl 2-(<2-(14)C>-2-aminothiazol-4-yl)-2-syn-methoximinoacetate

ethyl 2-(<2-(14)C>-2-tritylaminothiazol-4-yl)-2-syn-methoximinoacetate

ethyl 2-(<2-(14)C>-2-tritylaminothiazol-4-yl)-2-syn-methoximinoacetate

Conditions
ConditionsYield
With triethylamine 1.) -35 deg C to room temp., 1 h, 2.) room temp., 9 h;100%
trityl chloride
76-83-5

trityl chloride

trifluoroacetyl triflate
68602-57-3

trifluoroacetyl triflate

triphenylmethyl trifluoromethanesulfonate
115726-23-3

triphenylmethyl trifluoromethanesulfonate

Conditions
ConditionsYield
In tetrachloromethane at 25℃; for 3h;100%
trityl chloride
76-83-5

trityl chloride

(E)-methyl 3-(1H-imidazol-4-yl)acrylate
70346-51-9

(E)-methyl 3-(1H-imidazol-4-yl)acrylate

trans-1-trityl-4-imidazoleacrylic acid methyl ester
138408-36-3

trans-1-trityl-4-imidazoleacrylic acid methyl ester

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 0.5h; Ambient temperature;100%
With triethylamine In tetrahydrofuran at 0 - 20℃;97%
With triethylamine In N,N-dimethyl-formamide for 3h; Ambient temperature;70%
trityl chloride
76-83-5

trityl chloride

N-benzylethylenediamine
4152-09-4

N-benzylethylenediamine

N-Benzyl-N'-(triphenylmethyl)ethane-1,2-diamine
141856-06-6

N-Benzyl-N'-(triphenylmethyl)ethane-1,2-diamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;100%
With triethylamine In acetonitrile at 0 - 30℃; for 1h; Inert atmosphere;100%
With triethylamine In dichloromethane for 1h; 0 deg C to r.t.;83%

Triphenylmethyl chloride Chemical Properties

Molecular Structure of Chlorotriphenylmethane (CAS NO.76-83-5):

IUPAC Name: [chloro(diphenyl)methyl]benzene
Molecular formula: C19H15Cl
Molar mass: 278.78 g/mol
H bond acceptors: 0
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 0 Å2
Index of Refraction: 1.607
Molar Refractivity: 84.38 cm3
Molar Volume: 244.1 cm3
Surface Tension: 42.3 dyne/cm
Density: 1.141 g/cm3
Flash Point: 177.9 °C
Storage temp: Store under Nitrogen
Solubility: chloroform: 0.1 g/mL
Sensitive: Lachrymatory
BRN: 397363
Enthalpy of Vaporization: 59.73 kJ/mol
Boiling Point: 374.3 °C at 760 mmHg
Vapour Pressure: 1.82E-05 mmHg at 25°C
Melting point: 109-112°C
InChI
InChI=1/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
Smiles
C(c1ccccc1)(c1ccccc1)(c1ccccc1)Cl
 EINECS: 200-986-4
Product Categories: Amino Acid Derivatives; Starting Raw Materials & Intermediates; Organics; N-Protecting Reagents; Biochemistry; Nucleosides, Nucleotides & Related Reagents; Protecting Agents for Hydroxyl and Amino Groups; Protecting Agents, Phosphorylating Agents & Condensing Agents; Protection & Derivatization Reagents (for Synthesis); Synthetic Organic Chemistry; Regant series

Triphenylmethyl chloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 180mg/kg (180mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04021,

Triphenylmethyl chloride Safety Profile

Hazard Codes: CorrosiveC,DangerousN
Risk Statements: 34-50/53-14-36/37
R34:Causes burns. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R14 :Reacts violently with water. 
R36/37:Irritating to eyes and respiratory system.
Safety Statements: 26-36/37/39-45-61-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S27:Take off immediately all contaminated clothing.
RIDADR: UN 3261 8/PG 3
WGK Germany: 3
RTECS: PA6450000
F: 10-19-21
Hazard Note: Irritant
HazardClass: 8

Triphenylmethyl chloride Specification

  Chlorotriphenylmethane , with CAS number of 76-83-5, can be called [Chloro(diphenyl)methyl]benzene ; 1,1’,1’’-(chloromethylidyne)tris-benzen ; 1,1’,1’’(-Chloromethylidyne)trisben-zene ; chlorotriphenyl-methan ; Methane, chlorotriphenyl- ; alpha-chlorotriphenylmethane ; Benzene, 1,1',1''-(chloromethylidyne)tris- . It is a white solid . Sometimes it is used to introduce the trityl protecting group because it's an alkyl halide. Chlorotriphenylmethane (CAS NO.76-83-5) can be intermediates to produce drug especially for cephalosporins and be synthesized to idoxuridine for the anti-viral effect.

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