Uridine 5'-(tetrahydrogen triphosphate) supplier

Name
Uridine 5'-triphosphate
EINECS 200-558-7
CAS No. 63-39-8
Article Data48
CAS DataBase
Density 2.106 g/cm³
Solubility
Melting Point
Formula C₉H₁₅N₂O₁₅P₃
Boiling Point
Molecular Weight 484.144
Flash Point 113oC
Transport Information
Appearance
Safety 22-26-36
Risk Codes 20/21/22-68/20/21/22
Molecular Structure
Hazard Symbols Xn
Synonyms Magnesium Uridine Triphosphate;Magnesium UTP;Mg UTP;Mg-UTP;Triphosphate, Magnesium Uridine;Triphosphate, Uridine;Uridine Triphosphate;UTP;UTP, Magnesium
PSA 293.80000
LogP -2.50090

Synthetic route

: 58-97-9
5'-Uridylic Acid

A: 58-98-0
UDP

B: 63-39-8
UTP

Conditions

Conditions	Yield
With N-ethylmorpholine buffer; phosphorotriimidazolide at 22℃; for 72h; other 5'-nucleotides, also with phosphorotribenzimidazolide, MnCl2; other time, temperature;	A 25% B 36%
With phosphorotriimidazolide; magnesium chloride at 22℃; for 72h; N-ethylmorpholine buffer (pH 7.0);	A 25% B 36%

: C9H14N2O16P4

: 63-39-8
UTP

Conditions

Conditions	Yield
With pyridine; water; iodine In N,N-dimethyl-formamide at 20℃; for 2.25h;	9.3%

: 65-86-1
orotic acid

: 63-39-8
UTP

Conditions

Conditions	Yield
durch Biosynthese;

: 58-97-9
5'-Uridylic Acid

: 56-65-5
ATP

: 63-39-8
UTP

Conditions

Conditions	Yield
reversible enzymatische Bildung mit Hilfe von wss. Nucleosidmonophosphat-kinase aus Hefe-Praeparaten;
reversible enzymatische Bildung mit Hilfe von wss. Nucleosidmonophosphat-kinase aus Leber-Praeparaten;
reversible enzymatische Bildung mit Hilfe von wss. Nucleosidmonophosphat-kinase aus Erbsen-Samen;

: 13491-28-6, 13529-36-7, 28196-62-5, 65309-82-2, 18521-38-5
uridine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)

A: 42400-47-5
2-deoxy-α-D-glucopyranosyl

B: 63-39-8
UTP

Conditions

Conditions	Yield
With sodium pyrophosphate; uridine-5'-diphosphoglucose pyrophosohorylase; 2-amino-2-hydroxymethyl-1,3-propanediol; magnesium chloride; bovine serum albumin In water at 25℃; for 72h;

: 952585-00-1
uridine-5'-diphosphoglucose

A: 59-56-3, 2240-08-6, 2255-14-3, 2520-52-7, 6799-01-5, 10456-01-6, 14048-34-1, 15978-07-1, 19993-19-2, 20299-62-1, 40591-51-3, 62057-78-7, 77280-79-6, 78341-19-2
glucose 1-phosphate

B: 63-39-8
UTP

Conditions

Conditions	Yield
With UDPG pyrophosphorylase In water at 25℃; for 4h; Equilibrium constant; pH 7.2;

: 58-98-0
UDP

: 63-39-8
UTP

Conditions

Conditions	Yield
With polyphosphate; Escherichia coli polyphosphate kinase; tris hydrochloride In water at 37℃; for 16h;	49.6 % Chromat.
With rabbit muscle pyruvate kinase; potassium chloride; phosphoenolpyruvic acid; D,L-dithiothreitol at 20℃; pH=7.5; Kinetics; Concentration; Reagent/catalyst; Tris buffer;

O5'-<2-α-D-glucopyranosyl-1,2-dihydroxy-diphosphoryl>-uridine: O5'-<2-α-D-glucopyranosyl-1,2-dihydroxy-diphosphoryl>-uridine

: 63-39-8
UTP

Conditions

Conditions	Yield
With pyrophosphoric acid mit Hilfe von Glucose-1-phosphat-uridylyltransferase;

O5'--O2',O3'-isopropyliden-uridine: O5'--O2',O3'-isopropyliden-uridine

tetramethylammonium salt of diphosphoric acid-tribenzyl ester: tetramethylammonium salt of diphosphoric acid-tribenzyl ester

: 63-39-8
UTP

Conditions

Conditions	Yield
With acetonitrile anschl. mit m-Kresol und anschl. Hydrieren an Palladium/Kohle in wss. Aethanol und Behandeln mit wss. LiOH;

: 138-08-9
phosphoenolpyruvic acid

UDP: UDP

: 63-39-8
UTP

Conditions

Conditions	Yield
durch enzymatische Bildung mit Hilfe von Pyruvatkinase aus Kaninchenmuskelgewebe;

: 56-65-5
ATP

UDP: UDP

: 63-39-8
UTP

Conditions

Conditions	Yield
reversible enzymatische Bildung mit Hilfe von wss. Nucleosiddiphosphat-kinase aus Hefe-Praeparaten und tierischen Gewebeextrakten;
reversible enzymatische Bildung mit Hilfe von wss. Nucleosiddiphosphat-kinase aus Erbsen-Samen;

yeast RNA: yeast RNA

A: 86-01-1
guanosine 5'-triphosphate

B: 65-47-4
cytidine triphosphate

C: 63-39-8
UTP

D: 56-65-5
ATP

Conditions

Conditions	Yield
With sodium hydroxide; potassium phosphate; nuclease P1; PAN-immobilized PNPase; phospho(enol)pyruvic acid mono potassium salt; magnesium chloride; manganese(ll) chloride 1.) water, 50 deg C, 1 h, 2.) room temperature, 4 days; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

ribonucleic acid: ribonucleic acid

A: 63-39-8
UTP

B other nucleotides: other nucleotides

Conditions

Conditions	Yield
With magnesium oxide at 140 - 145℃; in wss. Loesung (pH 8 -8.5) und Behandeln des Nucleosid-Gemisches in wss. Loesung (pH ca. 7) in Gegenwart von Hefe und Dextrose mit NaH2PO4 und Na2HPO4;

: 58-97-9
5'-Uridylic Acid

: 538-75-0
dicyclohexyl-carbodiimide

A: 63-39-8
UTP

B UDP: UDP

Conditions

Conditions	Yield
With pyridine; tributyl-amine; phosphoric acid
With pyridine; phosphoric acid

...Expand

: C14H22N3O8P

: 63-39-8
UTP

Conditions

Conditions	Yield
With tris(tetra-n-butylammonium) hydrogen pyrophosphate In tetrahydrofuran at 20℃; for 0.5h;	45 mg

: 16628-81-2
2',3'-O-(methoxymethylidene)uridine

: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 690 mg / N-methylimidazole; pyridine / tetrahydrofuran / 20 °C 2: LiHMDS / tetrahydrofuran / 2 h / -78 - 0 °C 3: 215 mg / aq. HCl / acetonitrile / 4 h / 20 °C / pH 2.0 4: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 5: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme

: (4-Chloro-butyl)-methyl-phosphoramidic acid benzyl ester (3aR,4R,6R,6aR)-6-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-methoxy-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester

: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 215 mg / aq. HCl / acetonitrile / 4 h / 20 °C / pH 2.0 2: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 3: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme

: 727398-81-4
5'-uridyl benzyl N-methyl-N-(4-chlorobutyl)phosphoramidate

: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 2: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme

: 727399-01-1
(4-Chloro-butyl)-methyl-phosphoramidic acid benzotriazol-1-yl ester (3aR,4R,6R,6aR)-6-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-methoxy-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester

: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: LiHMDS / tetrahydrofuran / 2 h / -78 - 0 °C 2: 215 mg / aq. HCl / acetonitrile / 4 h / 20 °C / pH 2.0 3: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 4: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme

: 362-43-6
2',3'-O-isopropylideneuridine

: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine; chlorophosphoric acid dibenzyl ester / -40 - -30 °C / anschl. Hydrierung 2: aqueous H3PO4; aqueous pyridine View Scheme

: C9H11Cl2N2O7P

A: 58-97-9
5'-Uridylic Acid

B: 63-39-8
UTP

Conditions

Conditions	Yield
With tributyl-amine; bis(tri-n-butylammonium) pyrophosphate In N,N-dimethyl-formamide at -15℃; for 2h;	A n/a B 107 mg

: 58-96-8
uridine

A: 58-97-9
5'-Uridylic Acid

B: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: trichlorophosphate / trimethyl phosphite / 2 h / -15 °C 2: tributyl-amine; bis(tri-n-butylammonium) pyrophosphate / N,N-dimethyl-formamide / 2 h / -15 °C View Scheme

: 528-04-1, 2616-63-9, 7277-98-7, 16465-33-1, 19014-00-7, 26234-54-8, 26575-17-7, 27963-82-2, 29217-44-5, 125639-14-7
uridine 5'-diphospho-N-acetylglucosamine

: 63-39-8
UTP

Conditions

Conditions	Yield
With pyrophosphate tetraanion; recombinant Arabidopsis N-acetylglucosamine-1-phosphate uridylyltransferase-1; magnesium chloride at 37℃; for 0.166667h; pH=7.6; Kinetics; Concentration; Reagent/catalyst; aq. buffer; Enzymatic reaction;

: 528-04-1, 2616-63-9, 7277-98-7, 16465-33-1, 19014-00-7, 26234-54-8, 26575-17-7, 27963-82-2, 29217-44-5, 125639-14-7
uridine-5'-diphospho-N-acetyl-D-galactosamine

A: N-acetylgalactosamine-1-phosphate

B: 63-39-8
UTP

Conditions

Conditions	Yield
With pyrophosphate tetraanion; recombinant Arabidopsis N-acetylglucosamine-1-phosphate uridylyltransferase-1; magnesium chloride at 37℃; for 0.166667h; pH=7.6; Kinetics; Reagent/catalyst; Concentration; aq. buffer; Enzymatic reaction;

: 58-96-8
uridine

: 63-39-8
UTP

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 1.5 h / 20 °C / Inert atmosphere 2: pyridine; iodine; water / N,N-dimethyl-formamide / 2.25 h / 20 °C View Scheme

: 63-39-8
UTP

: 59-56-3
α-D-glucopyranosyl-1-phosphate

: 133-89-1
UDP-glucose

Conditions

Conditions	Yield
With Pasteurella multocida inorganic pyrophosphatase; Bifidobacterium longumuridine 5'-diphosphate-sugarpyrophosphorylase; adenosine-5'-triphosphate; magnesium chloride In aq. buffer at 37℃; for 2h; pH=8; Enzymatic reaction;	99%
With Glucose-1-phosphate thymidylyltransferase from Streptococcus pneumonia serotype 23F; magnesium chloride at 37℃; for 1h; Enzymatic reaction;	94%
With GalU; α(1->3) galactotransferase; α(1->4) galactotransferase; manganese(ll) chloride at 37℃; for 48h; pH=7; Inert atmosphere; aq. buffer; Enzymatic reaction;	70%

: N-azidoacetylgalactosamine

: 63-39-8
UTP

: 5’-diphospho-2-azidoacetamido galactosamine

Conditions

Conditions	Yield
With recombinant human GalNAc kinase GK2; recombinant human UDP-GalNAc pyrophosphorylase AGX1; ATP; yeast inorganic pyrophosphatase In various solvent(s) at 37℃; pH=8.8;	99%

: 59-56-3, 2240-08-6, 2255-14-3, 2520-52-7, 6799-01-5, 10456-01-6, 14048-34-1, 15978-07-1, 19993-19-2, 20299-62-1, 40591-51-3, 62057-78-7, 77280-79-6, 78341-19-2
glucose 1-phosphate

: 63-39-8
UTP

: 133-89-1
UDP-glucose

Conditions

Conditions	Yield
With recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; magnesium chloride at 37℃; for 2h; pH=8; aq. buffer; Enzymatic reaction;	99%
With yeast inorganic pyrophosphatase; recombinant Arabidopsis N-acetylglucosamine-1-phosphate uridylyltransferase-2; magnesium chloride at 37℃; for 0.166667h; pH=7.6; aq. buffer; Enzymatic reaction;

: 28446-21-1
N-acetylglucosamine-1-phosphate

: 63-39-8
UTP

: 528-04-1, 2616-63-9, 7277-98-7, 16465-33-1, 19014-00-7, 26234-54-8, 26575-17-7, 27963-82-2, 29217-44-5, 125639-14-7
uridine 5'-diphospho-N-acetylglucosamine

Conditions

Conditions	Yield
With yeast inorganic pyrophosphatase; N-acetylglucosamine-1-phosphate pyrophosphorylase from C. jejuni NCTC 11168; tris hydrochloride; magnesium chloride at 37℃; for 2h; pH=7.5;	97.9%
With Pyrococcus furiosus enzyme; magnesium(II) In various solvent(s) at 80℃; pH=7.5; Enzyme kinetics;
With Pyrococcus furious enzyme; magnesium(II) In various solvent(s) at 80℃; for 1h; pH=7.5;

: 667462-08-0
2-trifluoroacetamido-2-deoxy-α,β-D-glucopyranose

: 63-39-8
UTP

: 212137-54-7
uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside

Conditions

Conditions	Yield
With inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride In water at 37℃; pH=8; aq. buffer; Enzymatic reaction;	97%
With hydrogenchloride; N-acetylglucosamine-1-phosphate uridylyltransferase from Escherichia coli K12 MG1655; pyrophosphatase from Escherichia coli K12 MG1655; recombinant N-acetylhexosamine 1-kinase; ATP; magnesium chloride In aq. buffer at 37℃; pH=8.5; Concentration; Temperature; pH-value; Enzymatic reaction;
With inorganic pyrophosphatase from P. multocida; N-acetyl hexosamine 1-kinase from Bifidobacterium infantis; UDP-N-acetylgalactosamine pyrophosphorylase from Pasteurella multocida; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7; Enzymatic reaction;

: ammonium 2-acetamido-2,6-dideoxy-6-fluoro-α-D-glucopyranosyl-1-phosphate

: 63-39-8
UTP

: uridine 5'-diphospho-2-acetamido-2,6-dideoxy-6-fluoro-α-D-glucopyranose diammonium salt

Conditions

Conditions	Yield
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction;	95%

: ammonium 2-acetamido-2,6-dideoxy-6-thio-α-D-glucopyranosyl-1-phosphate

: 63-39-8
UTP

: uridine 5'-diphospho-2-acetamido-2,6-dideoxy-6-thio-α-D-glucopyranose diammonium salt

Conditions

Conditions	Yield
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride; D,L-dithiothreitol In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction;	93%

: 7226-39-3, 7241-17-0, 28876-44-0, 38711-37-4, 55449-80-4, 62182-10-9, 62182-14-3, 86783-82-6, 98856-44-1, 98856-45-2, 98856-46-3, 31077-88-0
2-deoxy-2-fluoro-D-mannopyranoside

: 63-39-8
UTP

: 67341-44-0
uridine 5'-diphospho-2-fluoro-2-deoxy-α-D-mannopyranoside

Conditions

Conditions	Yield
With recombinant Bifidobacterium infantis ATCC15697 N-acetylhexosamine 1-kinase; recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; ATP; magnesium chloride at 37℃; for 24h; pH=8; aq. buffer; Enzymatic reaction;	92%

: 2-deoxy-2-trifluoroacetamido-5-thio-D-glucose

: 63-39-8
UTP

: C17H24F3N3O16P2S

Conditions

Conditions	Yield
With ATP; magnesium chloride In aq. buffer at 37℃; for 36h;	92%

: 63-39-8
UTP

: 59-56-3, 2240-08-6, 2255-14-3, 2520-52-7, 6799-01-5, 10456-01-6, 14048-34-1, 15978-07-1, 19993-19-2, 20299-62-1, 40591-51-3, 62057-78-7, 77280-79-6, 78341-19-2
α-D-galactose-1-phosphate

: 2956-16-3
uridine 5'-diphospho-D-galactose

Conditions

Conditions	Yield
With inorganic pyrophosphatase; recombinant thymidylyltransferase from Aneurinibacillus thermoaerophilus DSM 10155; magnesium chloride at 55℃; for 1.5h; pH=7.5; Inert atmosphere; aq. buffer; Enzymatic reaction;	90%
With Glucose-1-phosphate thymidylyltransferase from Streptococcus pneumonia serotype 23F for 48h; Enzymatic reaction;	86%
With phosphate buffer; UDPG-PPase from Pyrococcus furiosus DSM 3638 at 90℃; pH=7.5; Enzyme kinetics;

: 97604-58-5
2-azido-2-deoxy-D-mannopyranose

: 63-39-8
UTP

: 1363386-22-4
uridine 5'-diphospho-2-azido-2-deoxy-α-D-mannopyranoside

Conditions

Conditions	Yield
With recombinant Bifidobacterium infantis ATCC15697 N-acetylhexosamine 1-kinase; recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; ATP; magnesium chloride at 37℃; for 24h; pH=8; aq. buffer; Enzymatic reaction;	90%

: 70021-34-0
D-glucuronic acid

: 63-39-8
UTP

: 2616-64-0
UDP-glucuronic acid

Conditions

Conditions	Yield
With glucuronokinase from Arabidopsis thaliana; pyrophosphatase from E. coli; UDP-sugar pyrophosphorylasegene from Arabidopsis thaliana; ATP; magnesium chloride In aq. buffer at 37℃; pH=8; Enzymatic reaction;	89%

: 10257-28-0
D-Galactose

: 63-39-8
UTP

: 2956-16-3
uridine 5'-diphospho-D-galactose

Conditions

Conditions	Yield
With recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Escherichia coli K-12 galactokinase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; ATP; magnesium chloride at 37℃; for 24h; pH=8; aq. buffer; Enzymatic reaction;	86%
With Pasteurella multocida inorganic pyrophosphatase; Bifidobacterium longumuridine 5'-diphosphate-sugarpyrophosphorylase; Echerichia coli galactokinase; adenosine-5'-triphosphate; magnesium chloride In aq. buffer at 37℃; for 24h; pH=8; Reagent/catalyst; Enzymatic reaction;	86%
With pyrophosphatase; Streptococcus pneumoniae TIGR4 galactokinase; Arabidopsis thaliana uridine-diphosphate-sugar pyrophosphorylase; ATP; magnesium chloride In aq. buffer at 42℃; for 1h; pH=8; Enzymatic reaction;
With galactokinase from Bifidobacterium infantis; inorganic pyrophosphatase from P. multocida; UDP-sugar pyrophosphorylase from Arabidopsis thaliana; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction;

: ammonium 2-acetamido-2,6-dideoxy-α-D-glucopyranosyl-1-phosphate

: 63-39-8
UTP

: uridine 5'-diphospho-2-acetamido-2,6-dideoxy-α-D-glucopyranose diammonium salt

Conditions

Conditions	Yield
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction;	86%

: C8H14NO9P(2-)*2Na(1+)

: 63-39-8
UTP

: 91183-98-1
P'-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] ester uridine 5'-(trihydrogen diphosphate), disodium salt

Conditions

Conditions	Yield
With 1,4-dithio-D,L-threitol; magnesium chloride at 30℃; for 3h; pH=7; aq. buffer; Enzymatic reaction;	85%

: ammonium 2-acetamido-6-azido-2,6-dideoxy-α-D-glucopyranosyl-1-phosphate

: 63-39-8
UTP

: uridine 5'-diphospho-2-acetamido-6-azido-2,6-dideoxy-α-D-glucopyranose diammonium salt

Conditions

Conditions	Yield
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride In aq. buffer at 37℃; for 48h; pH=7.5; Enzymatic reaction;	84%

: 72-87-7, 1136-42-1, 1136-44-3, 6730-06-9, 7772-94-3, 10036-64-3, 14131-60-3, 14131-64-7, 14131-68-1, 14215-68-0, 62057-49-2, 62057-50-5, 62057-51-6, 62057-52-7, 62057-53-8, 62057-54-9, 62057-55-0, 62057-56-1, 62075-50-7, 62137-54-6, 134451-97-1, 134522-12-6, 148347-16-4, 6082-29-7
N-acetyl-D-galactosamine

: 63-39-8
UTP

: 1146981-86-3
uridine 5'-diphospho-2-acetamido-2-deoxy-α-D-glacopyranoside

Conditions

Conditions	Yield
With Pasteurella multocida inorganic pyrophosphatase; Pasteurella multocida N-acetylglucosamine-1-phosphate uridylyltransferase; adenosine-5'-triphosphate; MTESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACCPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETHAIVADIMEAARLE; magnesium chloride In water at 37℃; for 24h; pH=8; Enzymatic reaction;	83%
With recombinant human GalNAc kinase GK2; recombinant human UDP-GalNAc pyrophosphorylase AGX1; ATP; yeast inorganic pyrophosphatase In various solvent(s) at 37℃; for 6h; pH=8.8;	68%
With pyrophosphatase; N-acetylhexosamine kinase; GalNAc pyrophosphorylase; ATP In aq. buffer at 37℃; pH=7.5; Enzymatic reaction;
With Bifidobacterium longum subsp. longum N-acetylhexosamine 1-kinase; Escherichia coli N-acetylglucosamine 1-phosphate uridyltransferase; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 7h; pH=8.5; Inert atmosphere; Enzymatic reaction;

: 7512-17-6, 72-87-7, 1136-42-1, 1136-44-3, 6082-29-7, 6730-06-9, 7772-94-3, 10036-64-3, 14131-60-3, 14131-64-7, 14131-68-1, 14215-68-0, 62057-49-2, 62057-50-5, 62057-51-6, 62057-52-7, 62057-53-8, 62057-54-9, 62057-55-0, 62057-56-1, 62075-50-7, 62137-54-6, 134451-97-1, 134522-12-6, 148347-16-4
N-Acetyl-D-glucosamine

: 63-39-8
UTP

: 528-04-1, 2616-63-9, 7277-98-7, 16465-33-1, 19014-00-7, 26234-54-8, 26575-17-7, 27963-82-2, 29217-44-5, 125639-14-7
uridine 5'-diphospho-N-acetylglucosamine

Conditions

Conditions	Yield
With inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride In water at 37℃; pH=8; aq. buffer; Enzymatic reaction;	81%
With Pasteurella multocida inorganic pyrophosphatase; Pasteurella multocida N-acetylglucosamine-1-phosphate uridylyltransferase; adenosine-5'-triphosphate; MTESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACCPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETHAIVADIMEAARLE; magnesium chloride In aq. buffer at 37℃; Enzymatic reaction;	81%
With inorganic pyrophosphatase; glucose-1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus DSM10155; N-acetylhexosamine kinase from Bifidobacterium longum; ATP; magnesium chloride In aq. buffer at 37 - 55℃; for 4h; pH=7.5; Enzymatic reaction;
With hydrogenchloride; N-acetylglucosamine-1-phosphate uridylyltransferase from Escherichia coli K12 MG1655; pyrophosphatase from Escherichia coli K12 MG1655; recombinant N-acetylhexosamine 1-kinase; ATP; magnesium chloride In aq. buffer at 37℃; pH=8.5; Concentration; Temperature; pH-value; Enzymatic reaction;
With inorganic pyrophosphatase from P. multocida; N-acetyl hexosamine 1-kinase from Bifidobacterium infantis; UDP-N-acetylgalactosamine pyrophosphorylase from Pasteurella multocida; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction;

: 63-39-8
UTP

: 34198-43-1, 73202-51-4, 80160-19-6
5-Iodo-UTP

Conditions

Conditions	Yield
With N-iodo-succinimide; sodium azide In water for 15h; regioselective reaction;	80%
With N-iodo-succinimide; sodium azide In water at 60℃; for 15h; regioselective reaction;	79%

: 6556-12-3, 489-91-8, 528-16-5, 552-12-5, 577-46-8, 643-33-4, 2240-07-5, 6294-16-2, 10133-02-5, 18402-78-3, 18968-14-4, 21179-08-8, 23018-83-9, 33599-45-0, 33599-46-1, 46171-67-9, 46171-69-1, 46172-26-3, 70021-34-0, 71031-08-8, 104195-06-4, 106499-29-0, 124817-72-7
D-glucuronic acid

: 63-39-8
UTP

: 2616-64-0
UDP-glucuronic acid

Conditions

Conditions	Yield
With recombinant Arabidopsis thaliana glucuronokinase; molecular weight around 42 kDa; recombinant Bifidobacterium longum UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida inorganic pyrophosphatase; ATP; magnesium chloride In aq. buffer at 37℃; for 36h; pH=6.5; Catalytic behavior; Reagent/catalyst; pH-value; Enzymatic reaction; chemoselective reaction;	80%
With glucuronokinase from Arabidopsis thaliana; inorganic pyrophosphatase from P. multocida; UDP-sugar pyrophosphorylase from Arabidopsis thaliana; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction;

: 2-deoxy-2-propionylamido-α-D-glucopyranosyl phosphate

: 63-39-8
UTP

: uridine-5'-(2-deoxy-2-propionylamido-α-D-glucopyranosyl diphosphate)

Conditions

Conditions	Yield
With yeast inorganic pyrophosphatase; N-acetylglucosamine-1-phosphate pyrophosphorylase from C. jejuni NCTC 11168; tris hydrochloride; magnesium chloride at 37℃; for 2h; pH=7.5;	79.9%

: 63-39-8
UTP

: 59-56-3, 2240-08-6, 2255-14-3, 2520-52-7, 6799-01-5, 10456-01-6, 14048-34-1, 15978-07-1, 19993-19-2, 20299-62-1, 40591-51-3, 62057-78-7, 77280-79-6, 78341-19-2
mannose-1-phosphate

: 133-89-1, 2956-16-3, 7307-71-3, 7349-77-1, 16375-64-7, 16375-65-8, 16414-46-3, 17012-87-2, 25318-68-7, 78391-94-3, 99020-05-0, 99945-86-5
Uridine diphosphate mannose

Conditions

Conditions	Yield
With Glucose-1-phosphate thymidylyltransferase from Streptococcus pneumonia serotype 23F for 48h; Enzymatic reaction;	78%
With phosphate buffer; UDPG-PPase from Pyrococcus furiosus DSM 3638 at 90℃; pH=7.5; Enzyme kinetics;
With phosphate buffer; UDPG-PPase from Pyrococcus furiosus DSM 3638; magnesium chloride at 90℃; for 0.5h;	92 % Turnov.

: 10257-28-0
D-Galactose

: 63-39-8
UTP

: 133-89-1, 2956-16-3, 7307-71-3, 7349-77-1, 16375-64-7, 16375-65-8, 16414-46-3, 17012-87-2, 25318-68-7, 78391-94-3, 99020-05-0, 99945-86-5
uridine-5'-diphosphogalactose

Conditions

Conditions	Yield
With galactokinase; pyruvate kinase; inorganic pyrophosphatase; phosphoenolpyruvic acid; galactose-1-phosphate uridylyltransferase; GalU; ATP; uridine-5'-diphosphoglucose at 30℃; for 24h; pH=8; aq. phosphate buffer; Inert atmosphere;	78%
With inorganic pyrophosphatase; galactokinase from Meiothermus taiwanensis; UDP-sugar pyrophosphorylase pyrophosphorylase from Arabidopsis thaliana; ATP; magnesium chloride In aq. buffer at 42℃; for 1h; pH=9; Enzymatic reaction;

: 2-Deoxy-2-[(trifluoroacetyl)amino]-D-glucopyranose-1-(dihydrogen phosphate) disodium salt

: 63-39-8
UTP

: P'-[2-deoxy-2-[(2,2,2-trifluoroacetyl)amino]-α-D-glucopyranosyl] ester uridine 5'-(trihydrogen diphosphate), disodium salt

Conditions

Conditions	Yield
With 1,4-dithio-D,L-threitol; magnesium chloride at 30℃; for 3h; pH=7; aq. buffer; Enzymatic reaction;	78%

: 20816-58-4, 116273-87-1
adenosine 5'-phosphorimidazolide

: 63-39-8
UTP

: P1-5'-O-adenosine-P4-5'-O-uridine tetraphosphate

Conditions

Conditions	Yield
With H96F-Fhit; magnesium chloride In various solvent(s) at 20℃; for 1h; pH=5.5;	73%

: 63-39-8
UTP

: 2-acetamido-6-azido-2,6-dideoxy-D-glucopyranoside

: 1202854-85-0
uridine 5'-diphospho-2-acetamido-6-azido-2,6-dideoxy-α-D-glucopyranoside

Conditions

Conditions	Yield
With inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride In water at 37℃; pH=8; aq. buffer; Enzymatic reaction;	72%

: 133-89-1
UDP-glucose

: 1375486-69-3
C6H13O8P

: 63-39-8
UTP

: 1346254-09-8
uridine-5'-diphospho-5-deoxy-D-galactofuranose

Conditions

Conditions	Yield
With inorganic pyrophosphatase; UDP-glucose pyrophosphorylase; galactose-1-phosphate uridyltransferase	71%

...Expand

: 884856-17-1
2-butyramido-2-deoxy-α-D-glucopyranosyl phosphate

: 63-39-8
UTP

: uridine-5'-(2-butyramido-2-deoxy-α-D-glucopyranosyl diphosphate)

Conditions

Conditions	Yield
With yeast inorganic pyrophosphatase; N-acetylglucosamine-1-phosphate pyrophosphorylase from C. jejuni NCTC 11168; tris hydrochloride; magnesium chloride at 37℃; for 2h; pH=7.5;	70.6%

: 133-89-1
UDP-glucose

: 63-39-8
UTP

: 6-deoxy-α-D-galactofuranosyl phosphate

: 1000874-38-3
uridine-5'-diphospho-6-deoxy-D-galactofuranose

Conditions

Conditions	Yield
With inorganic pyrophosphatase; UDP-glucose pyrophosphorylase; galactose-1-phosphate uridyltransferase	70%

...Expand

: C8H14NO9P(2-)*2Na(1+)

: 63-39-8
UTP

: 108320-87-2
P'-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl] ester uridine 5'-(trihydrogen diphosphate), disodium salt

Conditions

Conditions	Yield
With 1,4-dithio-D,L-threitol; magnesium chloride at 30℃; for 48h; pH=7; aq. buffer; Enzymatic reaction;	70%

Uridine 5'-(tetrahydrogen triphosphate) Chemical Properties

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-Dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Empirical Formula: C₉H₁₅N₂O₁₅P₃
Molecular Weight: 484.1411
Classification Code : Mutation data
Einecs: 200-558-7
Freely Rotating Bonds: 10
Polar Surface Area: 213.56 Å²
Index of Refraction: 1.643
Molar Refractivity: 83.19 cm³
Molar Volume: 229.8 cm³
Polarizability: 32.98 ×10^-24cm³
Surface Tension: 128.1 dyne/cm
Density: 2.106 g/cm³
The molecular structure of Uridine5'-(tetrahydrogen triphosphate) (CAS NO.63-39-8) is
.

Uridine 5'-(tetrahydrogen triphosphate) Uses

Uridine5'-(tetrahydrogen triphosphate) (CAS NO.63-39-8) is used as organic intermediate.

Uridine 5'-(tetrahydrogen triphosphate) Safety Profile

Hazard Codes: Harmful Xn
Risk Statements: 20/21/22-68-20/21/22
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R68: Possible risk of irreversible effects.
Safety Statements: 22-26-36
S22: Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 1

Uridine 5'-(tetrahydrogen triphosphate) Specification

The chemical synonyms of Uridine5'-(tetrahydrogen triphosphate) (CAS NO.63-39-8) are Uridine 5'-triphosphate ;Uridine 5'-triphosphoric acid ;Uridine triphosphate ;Uteplex .

Product Name

Uridine 5'-triphosphate

Synthetic route

Uridine 5'-(tetrahydrogen triphosphate) Chemical Properties

Uridine 5'-(tetrahydrogen triphosphate) Uses

Uridine 5'-(tetrahydrogen triphosphate) Safety Profile

Uridine 5'-(tetrahydrogen triphosphate) Specification

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