Conditions | Yield |
---|---|
With pyrographite; potassium hydroxide In water; isopropyl alcohol at 75℃; for 8h; pH=7.8 - 8; Product distribution / selectivity; Inert atmosphere; | 81% |
Product Name: Warfarin potassium (CAS NO.2610-86-8)
Molecular Formula: C19H15KO4
Molecular Weight: 346.4183g/mol
Mol File: 2610-86-8.mol
Boiling point: 515.2°C at 760mmHg
Flash Point: 188.8°C
Density: 1.307g/cm3
H-Bond Donor: 0
H-Bond Acceptor: 4
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | 200mg/kg (200mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
dog | LD50 | oral | 200mg/kg (200mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
mouse | LD50 | intravenous | 232mg/kg (232mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
mouse | LD50 | oral | 760mg/kg (760mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
rabbit | LD50 | intravenous | 100mg/kg (100mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
rabbit | LD50 | oral | 800mg/kg (800mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
rat | LD50 | intravenous | 186mg/kg (186mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. | |
rat | LD50 | oral | 58mg/kg (58mg/kg) | Drugs in Japan Vol. 6, Pg. 918, 1982. |
Reported in EPA TSCA Inventory.
Poison by ingestion and intravenous routes. When heated to decomposition Warfarin potassium (CAS NO.2610-86-8) emits toxic fumes of K2O.
Warfarin potassium ,its CAS NO. is 2610-86-8,the synonyms is Athrombin-K (TN) ; Potassium 4-oxo-3-(3-oxo-1-phenyl-butyl)chromen-2-olate ; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, potassium salt (9CI) ; Antrombin K ; Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, potassium salt (8CI) ; Potassium 3-(a-Acetonylbenzyl)-4-hydroxycoumarin ; Potassium warfarin ; Potassium, [[3-(a-acetonylbenzyl)-2-oxo-2H-1-benzopyran-4-yl]oxy]- (7CI) .
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