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Cas:81-81-2
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryName:warfarin CAS:81-81-2 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability Product
Cas:81-81-2
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
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Cas:81-81-2
Min.Order:1 Kilogram
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Product name: Warfarin CAS No.: 81-81-2 Molecule Formula:C19H16O4 Molecule Weight:308.33 Purity: 98.0% Package: 25kg/drum Description:White crystals or white crystalline powder Manufacture Standards:Enterprise Standard
Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat
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Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin
Cas:81-81-2
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high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China
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Hangzhou KieRaychem Co.,Ltd.is located in Yuhang District of Hangzhou City and specialized in the chemical product customization, development, sales, import and export. Current business is focused on fine chemicals, pharmaceutical materials and inter
Warfarin Application:80010283
1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and
Conditions | Yield |
---|---|
With C23H24N2O6S*Li(1+) In tetrahydrofuran; dimethyl sulfoxide at 0℃; for 48h; Reagent/catalyst; Michael Addition; | 99% |
With lipase In water at 50℃; for 168h; Temperature; Michael Addition; Enzymatic reaction; | 99.1% |
With N-ethyl-N,N-diisopropylamine In water for 20h; Michael Addition; Reflux; | 93% |
Conditions | Yield |
---|---|
With polystyrene-divinylbenzene support prepared cyclohexanol as porogen with immobilized 1,5,7-triazabicyclo[4.4.0]dec-5-ene at 100℃; for 96h; Reagent/catalyst; Solvent; Temperature; Time; Michael Addition; Green chemistry; | 96% |
With L-proline In dimethyl sulfoxide at 20℃; for 15h; Michael addition; | 85% |
With rac-Pro-OH In dimethyl sulfoxide at 20℃; for 24h; | 80% |
With cetyltrimethylammonim bromide; 1,4-dihydropyridine-enolate In water at 20℃; for 10h; Michael addition; | 50% |
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 20℃; for 16h; | 84% |
4-hydroxy[1]benzopyran-2-one
1-hydroxy-1-phenyl-3-butanone
warfarin
Conditions | Yield |
---|---|
With cyclopentene In chlorobenzene; toluene at 100℃; for 8h; Inert atmosphere; regioselective reaction; | 83% |
3-(phenyl-λ3-iodanylidene)chromane-2,4-dione
(E)-benzalacetone
warfarin
Conditions | Yield |
---|---|
In acetonitrile at 80℃; for 12h; | 76% |
(+/-)-Warfarin 4-methyl ether
warfarin
Conditions | Yield |
---|---|
With boron tribromide In dichloromethane -78 up to 0 deg C; |
2-methoxywarfarin
warfarin
Conditions | Yield |
---|---|
With boron tribromide In dichloromethane -78 up to 0 deg C; |
4-hydroxy[1]benzopyran-2-one
2-Methoxypropene
benzaldehyde
warfarin
Conditions | Yield |
---|---|
Stage #1: 4-hydroxy[1]benzopyran-2-one; 2-Methoxypropene; benzaldehyde With ethylenediamine diacetic acid In 1,4-dioxane at 90℃; for 4h; tandem Knoevenagel-hetero-Diels-Alder reaction; Stage #2: With hydrogenchloride; silica gel In water; trifluoroacetic acid at 20℃; |
Conditions | Yield |
---|---|
In water |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1-n-butyl-3-methylimidazolim bromide; bovine serum albumin; tetrabutylammomium bromide / 4 h / 60 °C / Inert atmosphere; Enzymatic reaction 2: 48 h View Scheme | |
Multi-step reaction with 2 steps 1: sodium hydroxide / water / Microwave irradiation 2: N-ethyl-N,N-diisopropylamine / water / 20 h / Reflux View Scheme | |
Multi-step reaction with 2 steps 1: Fe3O4(at)L-proline/Pd2 NCs / 24 h / 70 °C / Sealed tube 2: water / 12 h / 100 °C View Scheme |
warfarin
(1R,2S,5R)-menthyl chloroformate
Conditions | Yield |
---|---|
With TEA In 1,2-dichloro-ethane for 0.5h; Ambient temperature; | 100% |
warfarin
N-methoxylamine hydrochloride
4-hydroxy-3-(3-(methoxyimino)-1-phenylbutyl)-2H-1-benzopyran-2-one
Conditions | Yield |
---|---|
With pyridine In methanol at 20℃; for 18h; | 99% |
Conditions | Yield |
---|---|
With copper(l) iodide In pyridine at 55 - 60℃; for 5h; air; | A 98% B n/a |
warfarin
Methylenetriphenylphosphorane
4-hydroxy-3-(3-methyl-1-phenyl-3-butenyl)-2H-1-benzopyran-2-one
Conditions | Yield |
---|---|
In tetrahydrofuran; dimethyl sulfoxide | 95% |
In tetrahydrofuran; dimethyl sulfoxide | 65% |
warfarin
3-nitro-benzaldehyde
4-hydroxy-3-[5-(3-nitro-phenyl)-3-oxo-1-phenyl-pent-4-enyl]-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 95% |
warfarin
4-chlorobenzaldehyde
4-hydroxy-3-[5-(4-chloro-phenyl)-3-oxo-1-phenyl-pent-4-enyl]-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 93% |
warfarin
2-chloro-benzaldehyde
4-hydroxy-3-[5-(2-chloro-phenyl)-3-oxo-1-phenyl-pent-4-enyl]-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 93% |
warfarin
4-nitrobenzaldehdye
4-hydroxy-3-[5-(4-nitro-phenyl)-3-oxo-1-phenyl-pent-4-enyl]-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 93% |
warfarin
3-fluoro-3-(1-phenyl-3-oxobutyl)-2H-benzopyran-2,4-dione
Conditions | Yield |
---|---|
With N-fluorobis<(trifluoromethyl)sulfonyl>imide In chloroform; water at 35℃; for 0.25h; | 92% |
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 5h; | A 85% B n/a |
furfural
warfarin
4-hydroxy-3-(5-furan-2-yl-3-oxo-1-phenyl-pent-4-enyl)-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 85% |
warfarin
benzaldehyde
4-hydroxy-3-(3-oxo-1,5-diphenyl-pent-4-enyl)-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 85% |
warfarin
4-methoxy-benzaldehyde
4-hydroxy-3-[5-(4-methoxy-phenyl)-3-oxo-1-phenyl-pent-4-enyl]-chromen-2-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; | 85% |
Conditions | Yield |
---|---|
With pyrographite; potassium hydroxide In water; isopropyl alcohol at 75℃; for 8h; pH=7.8 - 8; Product distribution / selectivity; Inert atmosphere; | 81% |
warfarin
Conditions | Yield |
---|---|
With pyridine; sodium hydroxide; hydroxylamine hydrochloride In ethanol 1) 12 h, 2) reflux, 6 h; | 77% |
warfarin
vanadium(IV) fluoride
Conditions | Yield |
---|---|
In methanol methanolic soln. of VF4 added to methanolic soln. of C19H16O4 dropwise with stirring, mixt. had pH 3, refluxed for 2 h, kept overnight with stirring at room temp.; solvent removed on a rotary apparatus under reduced pressure; recrystn. (MeOH/n-hexane, 1/1); elem. anal., detd. by thermal anal.; | 77% |
warfarin
1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 26h; Inert atmosphere; | 75% |
warfarin
acetic anhydride
4-acetoxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
Conditions | Yield |
---|---|
for 1h; Heating; | 71.4% |
Conditions | Yield |
---|---|
In ethanol; water Heating; stereoselective reaction; | 68% |
Conditions | Yield |
---|---|
In acetone at 45℃; for 48h; | 65% |
warfarin
trifluoromethylsulfonic anhydride
trifluoro-methanesulfonic acid 2-oxo-3-(3-oxo-1-phenyl-butyl)-2H-chromen-4-yl ester
Conditions | Yield |
---|---|
With triethylamine In chloroform at -5 - 25℃; | 62% |
Conditions | Yield |
---|---|
With pentamethylcyclopentadienyl(benzene)cobalt(III) hexafluorophosphate; potassium carbonate; silver carbonate In 2-methyltetrahydrofuran at 60℃; for 16h; Inert atmosphere; Sealed tube; | 56% |
methanol
warfarin
2-methoxy-2-methyl-4-phenyl-3,4-dihydropyrano[3,2-c]chromen-5(2H)-one
Conditions | Yield |
---|---|
With hydrogenchloride for 23h; Reflux; | A 53% B 9% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone at 25℃; for 24h; | 38% |
warfarin
4'-Hydroxywarfarin
Conditions | Yield |
---|---|
With culture of Cunninghamella bainieri In water for 144h; Product distribution; Ph7 phosphate buffer; metabolism of warfarin to 4'-hydroxywarfarin using the fungus Cunninghamella bainiery, possible mechanism of aromatic hydroxylation, primary isotope effect; inhibition of hydroxylation by CO; | 2 mg |
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