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Shanghai Dynamic Industrial Co.,Ltd.

more information, please contact us

4-Hydroxycoumarin

Cas:1076-38-6

Min.Order:0

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Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for t

4-Hydroxycoumarin suppliers in China

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White or pale-white crystalline powder Conforms Melting point

High purity 4-Hydroxycoumarin with high quality cas:1076-38-6

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $50.0 / 80.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Hydroxy Coumarin supplier in China

Cas:1076-38-6

Min.Order:0 Metric Ton

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Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name 4-Hydroxycoumarin CAS number 1076-38-6 Assay ≥99% Appearance White crystalline powder Capacity 100mt/year Application Pharmaceutical/pestici

4-Hydroxycoumarin

Cas:1076-38-6

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 4-Hydroxycoumarin Cas 1076-38-6 High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Store below +30°C Package:25kg/drum Application:pharmaceuti

High quality 4-Hydroxycoumarin Cas 1076-38-6 with best price

Cas:1076-38-6

Min.Order:25 Kilogram

FOB Price: $36.0 / 38.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-hydroxycoumarin

Cas:1076-38-6

Min.Order:1

Negotiable

Type:Other

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Wuhan Kemi-Works Chemical Co., Ltd

Stable quality 4-Hydroxycoumarin 1076-38-6 with high purity factory ISO9001 Appearance:White or off white crystalline powder Assay: 99.0% min Melting point:213℃-217 ℃ Sulfate residue :0.20% max Loss on drying:0.5% max Wuhan Kemi-Work

Stable quality 4-Hydroxycoumarin 1076-38-6 with high purity factory

Cas:1076-38-6

Min.Order:10 Gram

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract 4-Hydroxycoumarin HACCP manufacturer

Cas:1076-38-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

4-Hydroxycoumarin

Cas:1076-38-6

Min.Order:10 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA. Product quality, process, price and service 4-Hydroxycoumarin CAS 1076-38-6 4-Coumarinyl alcohol IN Stock 4-Hydroxy-1-benzopyran-2-one 1076-38-6 1076-38-6 CAS 1076-38-6 h

4-Hydroxycoumarin CAS 1076-38-6 4-Coumarinyl alcohol IN Stock 4-Hydroxy-1-benzopyran-2-one 1076-38-6

Cas:1076-38-6

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

CHENGDU YANXI is a comprehensive manufacturer and an international distribution of products throughout the world. Specialized in Scrap metal, Chemical raw materials, Paper products and color industry. We aim to become leading position in global dis

pharmaceutical intermediates 4 hydroxycoumarin

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Trading Company

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Hubei DiBo chemical co., LTD

Name:4-Hydroxycoumarin English Name: 4-Hydroxycoumarin CAS No.1076-38-6 Molecular formula:C9H6O3 Molecular weight: 162.14 Packaging Specification: 25kg/drum high purity 99%min stock Hubei DiBo Chemical Co., Ltd. was founded in 2009, is a

4-Hydroxycoumarin Manufacturer /CAS:1076-38-6/Chinese suppliers/Content is 99.5%

Cas:1076-38-6

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Product Name: 4-Hydroxycoumarin Synonyms: 4-HydroxycoumarinN;7-hydroxy-1-benzopyran-2-one;4-hydroxy-2h-1-benzopyran-2-on;COUMARINOL;HYDROXYCOUMARIN, 4-;2H-1-BENZOPYRAN-2-ONE, 4-HYDROXY-;4-coumarinyl alcohol;4-HYDROXY-CHROMEN-2-ONE CAS: 1076-38-6

4-Hydroxycoumarin 1076-38-6

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $300.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

CAS 1076-38-6 4-Monohydroxycoumarin / 4-Hydroxycoumarin

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

99% Pure CAS 1076-38-6 with competitive price

Cas:1076-38-6

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Chemical Name 4-Hydroxycoumarin Synonyms 4-Hydroxy-1-benzopyran-2-one; 4-Coumarinyl alcohol CAS No. 1076-38-6 EINECS No. 214-060-2

4-Hydroxy-1-benzopyran-2-one

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystals Storage:R.T Package:25kg/drum Application:Intermediates Transportation:Express/Sea/Air Port:Any port in China

Factory supply 99% 4-Hydroxycoumarin cas 1076-38-6

Cas:1076-38-6

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

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Purestar Chem Enterprise Co.,Ltd

Bulk 99% 4-Hydroxy-2H-1-Benzopyran-2-On/4-Hydroxycoumarin Powder Product Name: 4-Hydroxycoumarin Synonyms: 4-hydroxy-1-benzopyran-2-one; 4-coumarinyl alcohol; 4-Hydroxy-chromen-2-one; 4-hydroxy cou

Bulk 99% 4-Hydroxy-2H-1-Benzopyran-2-On/4-Hydroxycoumarin Powder

Cas:1076-38-6

Min.Order:100 Kilogram

FOB Price: $8.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermediate

Topsale 4-Hydroxycoumarin99%

Cas:1076-38-6

Min.Order:25 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Antioxidants, 4-Hydroxycoumarin CAS:1076-38-6

Cas:1076-38-6

Min.Order:1 Kilogram

FOB Price: $72.1 / 78.3

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

4-Hydroxycoumarin CAS:1076-38-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermed

4-Hydroxycoumarin CAS:1076-38-6

Cas:1076-38-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Hydroxycoumarin

Cas:1076-38-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory Supply 4-Hydroxycoumarin CAS 1076-38-6

Cas:1076-38-6

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4-Hydroxycoumarin

Cas:1076-38-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 4-Hydroxycoumarin Synonyms: 4-hydroxy-2h-1-benzopyran-2-on;COUMARINOL;HYDROXYCOUMARIN, 4-;2H-1-BENZOPYRAN-2-ONE, 4-HYDROXY-;4-coumarinyl alcohol;4-HYDROXY-CHROMEN-2-ONE;4-HYDROXYCOUMARIN;4-HYDROXYCUMARIN CAS: 1076-38-6 MF: C9H6

4-Hydroxycoumarin Supplier best quality

Cas:1076-38-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

4-Hydroxycoumarin CAS1076-38-6

Cas:1076-38-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Hydroxycoumarin

Cas:1076-38-6

Min.Order:0

Negotiable

Type:Manufacturers

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Synthetic route

carbon monoxide
201230-82-2

carbon monoxide

o-hydroxyacetophenone
118-93-4

o-hydroxyacetophenone

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With selenium; 1,5-Diazabicyclo[5.4.0]undec-5-ene In tetrahydrofuran at 90℃;100%
With selenium; 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 100℃; under 22800 Torr; for 30h;100%
With selenium; 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 100℃; under 22800 Torr; for 30h; Mechanism; carbonylation of alkyl aryl ketones with CO using stoichiometric amount of Se, variation of temperature and solvent;100%
With triethylamine In tetrahydrofuran at 80℃; under 7355.08 Torr; for 4h;95%
With nitrobenzene; 1,8-diazabicyclo[5.4.0]undec-7-ene; selenium In tetrahydrofuran at 90℃; under 22800 Torr; for 30h; Mechanism; catalytic carbonylation of alkyl aryl ketones with CO by Se in the presence of oxidizing agent;68%
4-allyloxy-2H-chromen-2-one
31005-07-9

4-allyloxy-2H-chromen-2-one

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sodium hydrogen telluride; acetic acid In ethanol for 2h; Heating;99%
With ammonium formate; palladium on activated charcoal In methanol for 1.5h; Heating;95%
With iodine In dimethyl sulfoxide at 120℃; for 0.5h;78%
ethyl 4-hydroxy-2-oxo-2H-chromene-3-carboxylate
1821-20-1

ethyl 4-hydroxy-2-oxo-2H-chromene-3-carboxylate

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With potassium hydroxide In methanol; water96%
o-hydroxyacetophenone
118-93-4

o-hydroxyacetophenone

Diethyl carbonate
105-58-8

Diethyl carbonate

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sodium hydride In toluene at 0℃; for 4.5h; Reflux;95%
With sodium hydride In toluene at 100℃; for 3h;85%
Stage #1: o-hydroxyacetophenone With sodium hydride In toluene; mineral oil
Stage #2: Diethyl carbonate In toluene; mineral oil Reflux;
Stage #3: With hydrogenchloride In water
85%
2-oxo-2H-chromen-4-yl propionate
120450-94-4

2-oxo-2H-chromen-4-yl propionate

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sodium hydrogen telluride In ethanol for 0.5h; Quantum yield; Heating; buffer: deoxygen. acetic acid;95%
4-(piperidin-1-yl)-2H-chromen-2-one
14290-47-2

4-(piperidin-1-yl)-2H-chromen-2-one

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With hydrogenchloride for 0.5h; Product distribution; Heating;94%
3-carbethoxy-4-hydroxycoumarin
66530-08-3

3-carbethoxy-4-hydroxycoumarin

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sulfuric acid In ethanol; water at 100 - 105℃; for 1h; Hydrolysis; decarboxylation;90.5%
3-acetyl-chroman-2,4-dione
326925-91-1

3-acetyl-chroman-2,4-dione

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sulfuric acid In ethanol; water for 1h; Deacetylation; Heating;90.2%
N,N-diethyl-3-(2-hydroxyphenyl)-3-oxopropanamide
211449-34-2

N,N-diethyl-3-(2-hydroxyphenyl)-3-oxopropanamide

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With trifluoroacetic acid In toluene for 1h; Heating;89%
C12H14BF2NO5S

C12H14BF2NO5S

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

3-(2-Hydroxy-phenyl)-N,N-dimethyl-3-oxo-propionamide
144224-85-1

3-(2-Hydroxy-phenyl)-N,N-dimethyl-3-oxo-propionamide

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile at 50℃; for 0.5h;A 7%
B 87%
With sodium hydrogencarbonate In acetonitrile at 50℃; for 1h;A 25%
B 66%
o-hydroxyacetophenone
118-93-4

o-hydroxyacetophenone

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sodium hydride In toluene at 100℃; for 3h;84%
malonic acid monophenyl ester
35756-54-8

malonic acid monophenyl ester

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With Eaton’s reagent at 70℃; for 1h;80%
With Eaton’s reagent In water for 2h; Reflux;63%
With eaton’s reagent at 70℃; for 4h; Neat (no solvent);
With Eaton’s reagent at 60 - 70℃;
C11H12BF2NO3

C11H12BF2NO3

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

3-(2-Hydroxy-phenyl)-N,N-dimethyl-3-oxo-propionamide
144224-85-1

3-(2-Hydroxy-phenyl)-N,N-dimethyl-3-oxo-propionamide

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile at 50℃; for 1h;A 14%
B 77%
With water In acetonitrile at 50℃; for 1h;A 69%
B 29%
C24H18O7
476000-77-8

C24H18O7

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

dimethyl 2-(4-methylphenyl)furan-3,4-dicarboxylate
82577-50-2

dimethyl 2-(4-methylphenyl)furan-3,4-dicarboxylate

Conditions
ConditionsYield
With hydrogenchloride In methanol Heating;A 77%
B 68%
n-butyl magnesium bromide
693-03-8

n-butyl magnesium bromide

C11H11NO5S

C11H11NO5S

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

4-butyl-2H-1-benzopyran-2-one
133380-32-2

4-butyl-2H-1-benzopyran-2-one

Conditions
ConditionsYield
With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; iron(III)-acetylacetonate In tetrahydrofuran at 0℃; for 0.166667h; Reagent/catalyst; Inert atmosphere;A 21%
B 70%
phosgene
75-44-5

phosgene

o-hydroxyacetophenone
118-93-4

o-hydroxyacetophenone

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sodium hydride In toluene at 100℃; for 3h;69%
2-trichloromethyl-4-chromone
36853-28-8

2-trichloromethyl-4-chromone

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With potassium hydroxide In methanol for 0.5h; Hydrolysis; Heating;65%
2-acetylphenyl 2-chlorobenzoate
84634-61-7

2-acetylphenyl 2-chlorobenzoate

methyl chloroformate
79-22-1

methyl chloroformate

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
Stage #1: 2-acetylphenyl 2-chlorobenzoate With sodium hydride In N,N-dimethyl-formamide at 100℃; for 6h; Inert atmosphere;
Stage #2: methyl chloroformate In N,N-dimethyl-formamide
59%
3-(phenyl-λ3-iodanylidene)chromane-2,4-dione
86795-49-5

3-(phenyl-λ3-iodanylidene)chromane-2,4-dione

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

3,4-Dihydroxy-2-oxo-2H<1>benzopyran
77889-64-6

3,4-Dihydroxy-2-oxo-2H<1>benzopyran

C

3-Acetoxy-4-hydroxy-2-oxo-2H<1>benzopyran

3-Acetoxy-4-hydroxy-2-oxo-2H<1>benzopyran

Conditions
ConditionsYield
With acetic acid for 0.0833333h; Heating;A n/a
B 13%
C 51%
3-(phenyl-λ3-iodanylidene)chromane-2,4-dione
86795-49-5

3-(phenyl-λ3-iodanylidene)chromane-2,4-dione

acetic acid
64-19-7

acetic acid

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

3,4-Dihydroxy-2-oxo-2H<1>benzopyran
77889-64-6

3,4-Dihydroxy-2-oxo-2H<1>benzopyran

C

3-Acetoxy-4-hydroxy-2-oxo-2H<1>benzopyran

3-Acetoxy-4-hydroxy-2-oxo-2H<1>benzopyran

Conditions
ConditionsYield
for 0.0833333h; Heating;A n/a
B 13%
C 51%
malonic acid
141-82-2

malonic acid

phenol
108-95-2

phenol

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With zinc(II) chloride; trichlorophosphate at 60 - 65℃; for 48h;50%
With zinc(II) chloride; trichlorophosphate at 60 - 70℃;48%
With zinc(II) chloride; trichlorophosphate at 60 - 65℃;41%
2-amino-3-formylchromone
61424-76-8

2-amino-3-formylchromone

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

2-(4-oxo-4H-[1]benzopyran-3-yl) [1] benzopyrano[3,2-e]pyrimidin-5(5H)-one
73262-21-2

2-(4-oxo-4H-[1]benzopyran-3-yl) [1] benzopyrano[3,2-e]pyrimidin-5(5H)-one

C

Bis-<1>benzopyrano<2,3-b:3',2'-e>pyridin-5(5H),7(7H)-dion
90701-02-3

Bis-<1>benzopyrano<2,3-b:3',2'-e>pyridin-5(5H),7(7H)-dion

Conditions
ConditionsYield
hydrogenchloride In isopropyl alcohol for 30h;A 26%
B 1%
C 38%
4-chloro-3-nitro-chromen-2-one
38464-20-9

4-chloro-3-nitro-chromen-2-one

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With pyridine; sodium dithionite In water27%
3-(phenyl-λ3-iodanylidene)chromane-2,4-dione
86795-49-5

3-(phenyl-λ3-iodanylidene)chromane-2,4-dione

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

C27H14O9

C27H14O9

Conditions
ConditionsYield
With trifluoroacetic acid Heating;A n/a
B 25%
4-(o-hydroxybenzoyl)-pyrazolone-5
91595-89-0

4-(o-hydroxybenzoyl)-pyrazolone-5

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 10h;15.6%
C18H12FN3O4S

C18H12FN3O4S

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

N-(4-fluorophenyl)-1,3,4-thiadiazole-2-carboxamide

N-(4-fluorophenyl)-1,3,4-thiadiazole-2-carboxamide

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃;A n/a
B 13%
C19H12F3N3O4S

C19H12F3N3O4S

A

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

B

N-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazole-2-carboxamide
1456793-06-8

N-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazole-2-carboxamide

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃;A n/a
B 9%
methyl acetylsalicylate
580-02-9

methyl acetylsalicylate

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Conditions
ConditionsYield
With sodium at 165 - 175℃;
sodium ethanolate
141-52-6

sodium ethanolate

o-hydroxyacetophenone
118-93-4

o-hydroxyacetophenone

Diethyl carbonate
105-58-8

Diethyl carbonate

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

sodium ethanolate
141-52-6

sodium ethanolate

o-hydroxyacetophenone
118-93-4

o-hydroxyacetophenone

Diethyl carbonate
105-58-8

Diethyl carbonate

benzene
71-43-2

benzene

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

3,3-(4'-methoxybenzylidene)bis(4-hydroxycoumarin)
10172-75-5

3,3-(4'-methoxybenzylidene)bis(4-hydroxycoumarin)

Conditions
ConditionsYield
With 4-sulfophthalic acid In water at 80℃; for 0.416667h; Catalytic behavior; Green chemistry;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 20℃; for 16h;99%
With phosphotungstic acid In water at 80℃; for 0.383333h; domino Knoevenagel type condensation/Michael reaction;99%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

3,3'-(4-chlorophenylmethylene)-bis-4-hydroxycoumarin
4322-59-2

3,3'-(4-chlorophenylmethylene)-bis-4-hydroxycoumarin

Conditions
ConditionsYield
With glycerol-based carbon sulfonic acid In ethanol; water at 80℃; for 0.333333h; Solvent; Temperature; Concentration;100%
With silica-supported Preyssler acid nanoparticles In ethanol at 25℃; for 0.333333h;99%
With cholin hydroxide In water at 50℃; for 2h;99%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

benzaldehyde
100-52-7

benzaldehyde

3,3'-phenylmethylene-bis-4-hydroxycoumarin
1821-19-8

3,3'-phenylmethylene-bis-4-hydroxycoumarin

Conditions
ConditionsYield
With cholin hydroxide In water at 50℃; for 1h; Catalytic behavior; Temperature; Reagent/catalyst;100%
With 4-sulfophthalic acid In water at 80℃; for 0.5h; Catalytic behavior; Green chemistry;99%
With C19H40KNO8S(2+)*2C2F3O2(1-) In ethanol; water for 0.5h; Reagent/catalyst; Reflux;98%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

phenol
108-95-2

phenol

2-oxo-2H-chromen-4-yl propionate
120450-94-4

2-oxo-2H-chromen-4-yl propionate

Conditions
ConditionsYield
With pyridine In benzene100%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

3,3'-((3-methoxyphenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)
10172-74-4

3,3'-((3-methoxyphenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)

Conditions
ConditionsYield
With 4-sulfophthalic acid In water at 80℃; for 0.333333h; Catalytic behavior; Green chemistry;100%
With piperidine In ethanol at 20℃; for 4h;98%
With 4-aminobenzene sulfonic acid In water at 80℃; for 0.366667h; Green chemistry;96%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

acetonitrile
75-05-8

acetonitrile

N-[(4-bromophenyl)(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]acetamide
1092452-47-5

N-[(4-bromophenyl)(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]acetamide

Conditions
ConditionsYield
With chlorosulfonic acid at 20℃; for 1h;100%
Stage #1: 4-hydroxy[1]benzopyran-2-one; 4-bromo-benzaldehyde; acetonitrile With phosphorus pentaoxide; Hexamethyldisiloxane at 20℃; for 3h;
Stage #2: With water cooling; Further stages.;
90%
pyrrolidine
123-75-1

pyrrolidine

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

benzaldehyde
100-52-7

benzaldehyde

4-hydroxy-3-(phenyl(pyrrolidin-1-yl)methyl)-2H-chromen-2-one
1330776-87-8

4-hydroxy-3-(phenyl(pyrrolidin-1-yl)methyl)-2H-chromen-2-one

Conditions
ConditionsYield
In dichloromethane at 20℃; for 2h; Mannich Aminomethylation;100%
With zinc(II) oxide In water at 25℃; for 0.416667h;93%
With Triton X-100 In water at 20℃; for 6h; Mannich type reaction;90%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

C8H7NO5
5000-63-5

C8H7NO5

malononitrile
109-77-3

malononitrile

2-amino-3-cyano-4-(3'-nitrobenzoyl)-4H,5H-pyrano[3,2-c]chromene-5-one
1613226-36-0

2-amino-3-cyano-4-(3'-nitrobenzoyl)-4H,5H-pyrano[3,2-c]chromene-5-one

Conditions
ConditionsYield
With zinc(II) oxide In ethanol; water at 20℃; for 1.83333h; Reflux; Green chemistry;100%
With ammonium dihydrogen phosphate In ethanol; water at 20℃; for 1.5h; Reflux;85%
With ammonium ferrous sulphate hexahydrate In ethanol; water at 20℃; for 2.33333h; Reflux; Green chemistry; chemoselective reaction;85%
With titanium(IV) oxide In ethanol; water at 20℃; for 2h; Reflux; Green chemistry;80%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

p-Chlorothiophenol
106-54-7

p-Chlorothiophenol

3-(4-chlorophenylsulfanyl)-4-hydroxy-2H-chromen-2-one

3-(4-chlorophenylsulfanyl)-4-hydroxy-2H-chromen-2-one

Conditions
ConditionsYield
With iodine; dimethyl sulfoxide In neat (no solvent) at 80℃; for 5h;100%
With sodium tetrafluoroborate; potassium iodide In acetonitrile at 60℃; for 6h; Temperature; Electrolysis;94%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

thiophenol
108-98-5

thiophenol

4-hydroxy-3-(phenylsulfanyl)-2H-chromen-2-one
18714-37-9

4-hydroxy-3-(phenylsulfanyl)-2H-chromen-2-one

Conditions
ConditionsYield
With iodine; dimethyl sulfoxide In neat (no solvent) at 80℃; for 5h;100%
With iodine In dimethyl sulfoxide at 80℃; for 3h;92%
With tetrabutylammomium bromide; iodine; oxygen; bovine serum albumin In water at 50℃; for 8h; Green chemistry;
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

1-Phenylbut-1-en-3-one
122-57-6

1-Phenylbut-1-en-3-one

warfarin
81-81-2

warfarin

Conditions
ConditionsYield
With C23H24N2O6S*Li(1+) In tetrahydrofuran; dimethyl sulfoxide at 0℃; for 48h; Reagent/catalyst; Michael Addition;99%
With lipase In water at 50℃; for 168h; Temperature; Michael Addition; Enzymatic reaction;99.1%
With N-ethyl-N,N-diisopropylamine In water for 20h; Michael Addition; Reflux;93%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

salicylaldehyde
90-02-8

salicylaldehyde

3,3'‑(2‑hydroxyphenylmethylene)bis(4‑hydroxy‑2H‑chromen-2‑one)
21549-90-6

3,3'‑(2‑hydroxyphenylmethylene)bis(4‑hydroxy‑2H‑chromen-2‑one)

Conditions
ConditionsYield
With cholin hydroxide In water at 50℃; for 1h;99%
With phosphotungstic acid In water at 80℃; for 0.333333h; domino Knoevenagel type condensation/Michael reaction;98%
With Sulfonic Acid Functionalized Nanoporous Silica (SBA-Pr-SO3H) In ethanol; water for 0.5h;98%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

(E/Z)-3,7-dimethyl-2,6-octadienal
5392-40-5

(E/Z)-3,7-dimethyl-2,6-octadienal

2-methyl-2-(4-methylpent-3-enyl)-2H,5H-pyrano<3,2-c><1>benzopyran-5-one
132356-42-4

2-methyl-2-(4-methylpent-3-enyl)-2H,5H-pyrano<3,2-c><1>benzopyran-5-one

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere;99%
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
With ethylenediamine diacetic acid In methanol for 3h; Ambient temperature;70%
With water at 80℃; for 6h; Domino Knoevenagel/6ϖ-electrocyclization;64%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

acetic anhydride
108-24-7

acetic anhydride

4-acetoxycoumarin
15059-36-6

4-acetoxycoumarin

Conditions
ConditionsYield
With 4-(dimethylamino)pyridine hydrochloride In toluene at 60℃; for 4h;99%
Stage #1: 4-hydroxy[1]benzopyran-2-one With manganese(II) iodide; naphthalene; lithium In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: acetic anhydride In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;
85%
With potassium tropolonato In acetonitrile at 70℃; for 4h;72%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)-(4-nitro-phenyl)-methyl]-chromen-2-one
10172-70-0

4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)-(4-nitro-phenyl)-methyl]-chromen-2-one

Conditions
ConditionsYield
With N,N,N',N'-tetramethylguanidinium acetate at 25℃; for 2h;99%
With copper chromite nanoparticles In water at 20℃; for 0.0166667h; Green chemistry;99%
With 1,4-diazabicyclo[2.2.2]octane hydroacetate In water at 80℃; for 0.0833333h; Green chemistry;99%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

3,3′‐[(4‐dimethylaminophenyl)methylene]bis(4‐hydroxy‐2H‐chromen‐2‐one)
10172-76-6

3,3′‐[(4‐dimethylaminophenyl)methylene]bis(4‐hydroxy‐2H‐chromen‐2‐one)

Conditions
ConditionsYield
With 2H4N2*2H(1+)*F6Si(2-) In ethanol for 0.0333333h; Reflux; Green chemistry;99%
With glycerol-based carbon sulfonic acid In ethanol; water at 80℃; for 0.25h;96%
With lemon juice In water at 27 - 30℃; for 2.5h;96%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

malononitrile
109-77-3

malononitrile

2-amino-4-(4-chlorophenyl)-4,5-dihydro-5-oxopyrano[3,2-c]chromene-3-carbonitrile
177028-89-6

2-amino-4-(4-chlorophenyl)-4,5-dihydro-5-oxopyrano[3,2-c]chromene-3-carbonitrile

Conditions
ConditionsYield
With Lipase from Thermomyces lanuginosus immobilized on particle silica gel In water; dimethyl sulfoxide at 45℃; for 16h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature;99%
With urea functionalized silica coated magneticcor shell Fe3-xTixO4 nanoparticle In ethanol; water for 0.25h; Reagent/catalyst; Reflux;98%
With perchloric acid modified cellulose In neat (no solvent) at 70℃; for 0.1h; Green chemistry;98%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

β-naphthaldehyde
66-99-9

β-naphthaldehyde

4-hydroxy-3-((4-hydroxy-2-oxo-2H-chromen-3-yl)(naphthalen-2-yl)methyl)-2H-chromen-2-one

4-hydroxy-3-((4-hydroxy-2-oxo-2H-chromen-3-yl)(naphthalen-2-yl)methyl)-2H-chromen-2-one

Conditions
ConditionsYield
With 1,4-diazabicyclo[2.2.2]octane hydroacetate In water at 80℃; for 0.1h; Green chemistry;99%
In ethanol for 24h; Heating;97%
With sulfonic acid-functionalized mesoporous silica nanoparticles In water at 80℃; for 0.25h; Green chemistry;95%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

terephthalaldehyde,
623-27-8

terephthalaldehyde,

NSC 158393
107421-16-9

NSC 158393

Conditions
ConditionsYield
With 1,4-diazabicyclo[2.2.2]octane hydroacetate In water at 80℃; for 0.0833333h; Green chemistry;99%
With sulfuric acid-modified polyethyleneglycol-6000 In neat (no solvent) at 70℃; for 0.0666667h; Knoevenagel Condensation; Green chemistry;98%
In water at 150℃; for 0.166667h; Microwave irradiation;86%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

SKI-213271

SKI-213271

Conditions
ConditionsYield
With cholin hydroxide In water at 50℃; for 1h;99%
With phosphotungstic acid In water at 80℃; for 0.25h; domino Knoevenagel type condensation/Michael reaction;98%
With sulfonic acid-functionalized mesoporous silica nanoparticles In water at 80℃; for 0.166667h; Green chemistry;98%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

3,3'‑(4‑bromophenylmethylene)‑bis(4‑hydroxy‑2H‑chromen‑2‑one)

3,3'‑(4‑bromophenylmethylene)‑bis(4‑hydroxy‑2H‑chromen‑2‑one)

Conditions
ConditionsYield
With 1,4-diazabicyclo[2.2.2]octane hydroacetate In water at 80℃; for 0.0333333h; Green chemistry;99%
With Triton X-100 In water at 20℃; for 6h; Knoevenagel Condensation; Green chemistry;98%
In toluene at 90℃; for 0.25h; Reagent/catalyst;98%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

butyraldehyde
123-72-8

butyraldehyde

3,3'-(butane-1,1-diyl)bis(4-hydroxy-2H-chromen-2-one).
1821-18-7

3,3'-(butane-1,1-diyl)bis(4-hydroxy-2H-chromen-2-one).

Conditions
ConditionsYield
With 1,4-diazabicyclo[2.2.2]octane hydroacetate In water at 80℃; for 0.1h; Green chemistry;99%
With poly(2-acrylamido-2-methylpropanesulphonic acid-co-acrylamide) supported on magnetite nanoparticles In toluene at 90℃; for 0.55h;94%
In toluene at 90℃; for 0.5h; Reagent/catalyst;94%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

3-methylbenzene-1,2-diol
488-17-5

3-methylbenzene-1,2-diol

3,4-dihydroxy-2-methyl-6H-benzofuro[3,2-c][1]benzopyron-6-one

3,4-dihydroxy-2-methyl-6H-benzofuro[3,2-c][1]benzopyron-6-one

Conditions
ConditionsYield
With Trametes versicolor laccase; oxygen In acetate buffer at 20℃; for 3h; pH=4.37;99%
With laccase from Trametes versicolor at 20℃; for 3h; pH=4.4; aq. acetate buffer; Enzymatic reaction; regioselective reaction;99%
With sodium acetate; potassium hexacyanoferrate(III) In water for 1h; Michael addition reaction;95%
With laccase In aq. phosphate buffer at 20℃; for 24h; pH=7.15; Enzymatic reaction;76%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

5-Nitrosalicylaldehyde
97-51-8

5-Nitrosalicylaldehyde

7-(4-hydroxy-2-oxo-2H-1-benzopyran-3-yl)-9-nitro-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-6-one

7-(4-hydroxy-2-oxo-2H-1-benzopyran-3-yl)-9-nitro-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-6-one

Conditions
ConditionsYield
at 80℃; for 2h;99%
With silica supported zirconium hydrogen sulfate In neat (no solvent) at 60℃; for 0.75h;99%
With TiO2-carbon nanotubes nanocomposite In water at 20℃; for 2h; Green chemistry;98%
isoquinoline
119-65-3

isoquinoline

4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

Cyclohexyl isocyanide
931-53-3

Cyclohexyl isocyanide

C25H24N2O3
1013099-16-5

C25H24N2O3

Conditions
ConditionsYield
In water at 70℃; for 12h;99%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

C17H18O3
1198426-96-8

C17H18O3

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

(E)-1,1,1-trifluoro-4-phenyl-3-buten-2-one
3108-32-5, 86571-25-7

(E)-1,1,1-trifluoro-4-phenyl-3-buten-2-one

(4R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)-3,4-dihydropyrano[3,2-c]chromen-5-(2H)one
1244390-29-1

(4R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)-3,4-dihydropyrano[3,2-c]chromen-5-(2H)one

Conditions
ConditionsYield
With C29H29F6N3OS In toluene for 5h; Michael addition; optical yield given as %ee; enantioselective reaction;99%
4-hydroxy[1]benzopyran-2-one
1076-38-6

4-hydroxy[1]benzopyran-2-one

methyl benzylidenepyruvate
107969-78-8

methyl benzylidenepyruvate

(4R)-methyl 2-hydroxy-5-oxo-4-phenyl-2,3,4,5-tetrahydropyrano[3,2-c]chromene-2-carboxylate

(4R)-methyl 2-hydroxy-5-oxo-4-phenyl-2,3,4,5-tetrahydropyrano[3,2-c]chromene-2-carboxylate

Conditions
ConditionsYield
With C29H29F6N3OS In diethyl ether at 20℃; for 2h; Michael addition; optical yield given as %ee; enantioselective reaction;99%
With C37H31F6N3S at 20℃; for 12h; Solvent; Michael Addition; enantioselective reaction;92%
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