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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Methyl-5-(trifluoromethyl)-1H-pyrazole

Cas:10010-93-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Methyl-5-(trifluoromethyl)-pyrazole

Cas:10010-93-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE CAS 10010-93-2

Cas:10010-93-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 10010-93-2 with fast shipping

Cas:10010-93-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:white to orange powder, crystals crystalline powder and/or chunks Storage:R T Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Any port in China

Factory Price Ready Stock 3-Trifluoromethyl-5-(methyl)pyrazole

Cas:10010-93-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE Chemical Properties Melting point 88-90 °C(lit.) Boiling point 187℃ density 1.355 Fp 67℃ storage temp. Inert atmosphere,Room Temperature pka 11.12±0.10(Predicted) form Powder

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE。

Cas:10010-93-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Pyrazole,3-methyl-5-(trifluoromethyl)-

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

3-Methyl-5-(trifluoromethyl)-1H-pyrazole

Cas:10010-93-2

Min.Order:1 Gram

FOB Price: $98.0

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-Trifluoromethyl-5-(methyl)pyrazole

Cas:10010-93-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

5-methyl-3-(trifluoromethyl)-1H-pyrazole

Cas:10010-93-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Pyrazole,3-methyl-5-(trifluoromethyl)-

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE

Cas:10010-93-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1H-Pyrazole,3-methyl-5-(trifluoromethyl)- TIMTEC-BB SBB004075;CBI-BB ZERO/006128;BUTTPARK 29\08-72;BUTTPARK 76\07-66;ART-CHEM-BB B014453;3-TRIFLUOROMETHYL-5-(METHYL)PYRAZOLE;3-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE;3-METHYL-5-(TRIFLUOROMETHYL)PYR

10010-93-2

Cas:10010-93-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3-Methyl-5-(trifluoromethyl)-1H-pyrazole

Cas:10010-93-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE

Cas:10010-93-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Methyl-3-(trifluoromethyl)pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-Methyl-3-trifluoromethylpyrazole cas no. 10010-93-2 98%

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-Trifluoromethyl-5-(methyl)pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3-Methyl-5-(trifluoromethyl)pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

3-Methyl-5-(trifluoroMethyl)pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city?in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api,?intermediat

3-Methyl-5-(trifluoromethyl)pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-Methyl-5-trifluoroMethyl-1H-pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

3-methyl-5-(trifluoromethyl)-1H-pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE CAS No.10010-93-2

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white solid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary an

3-Trifluoromethyl-5-(methyl)pyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

3-Methyl-5-(trifluoromethyl)-1H-pyrazole cas 10010-93-2Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3-Methyl-5-(trifluoromethyl)-1H-pyrazole cas 10010-93-2

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Other

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

factory?direct?saleAppearance:powder Storage:In cool ,dry place Package:G/bottle; Kg/bag; 1664kg/barrel Application:for pharma use Transportation:Air or sea freight Port:Any main ports of China

3-methyl-5-trifluoromethylpyrazole

Cas:10010-93-2

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

1,1,1-Trifluoro-2,4-pentanedione
367-57-7

1,1,1-Trifluoro-2,4-pentanedione

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

Conditions
ConditionsYield
With hydrazine In methanol at 0 - 20℃; for 16h;95%
Stage #1: 1,1,1-Trifluoro-2,4-pentanedione With hydrazine hydrate In chloroform for 1h; Reflux;
Stage #2: With phosphorus pentoxide In chloroform for 3h; Reflux;
90%
With hydrazine hydrate In ethanol at 0℃; for 6h; Reflux; Inert atmosphere;82%
1-(1-pyrrolidinomethyl)-3-trifluoromethylpyrazole
155635-51-1

1-(1-pyrrolidinomethyl)-3-trifluoromethylpyrazole

methyl iodide
74-88-4

methyl iodide

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

Conditions
ConditionsYield
With n-butyllithium 1.) THF, -70 deg C, 2 h, 2.) THF, from -70 deg C to r.t.; Yield given. Multistep reaction;
1,1,1-Trifluoro-2,4-pentanedione
367-57-7

1,1,1-Trifluoro-2,4-pentanedione

A

3-methyl-5-(trifluoromethyl)pyrazole
10010-93-2

3-methyl-5-(trifluoromethyl)pyrazole

B

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 1,1,1-Trifluoro-2,4-pentanedione With hydrazine In 1,4-dioxane
Stage #2: In toluene Heating; Further stages.;
(Z)-9-octadecen-1-amine
112-90-3

(Z)-9-octadecen-1-amine

C15H12F9N6P

C15H12F9N6P

A

C54H108N3P

C54H108N3P

B

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

Conditions
ConditionsYield
at 50℃; for 0.0833333h;
5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazole
60061-68-9

4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
With bromine; sodium acetate; acetic acid at 0 - 20℃; for 21.1667h;100%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 25℃; for 1h;99%
5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

silver(l) oxide
20667-12-3

silver(l) oxide

([3-(CF3),5-(Me)Pz]Ag)3
937255-69-1

([3-(CF3),5-(Me)Pz]Ag)3

Conditions
ConditionsYield
In toluene (N2, dark); refluxing overnight mixt. of pyrazole deriv. and silver oxide in toluene; cooling filtration through celite, evapn., elem. anal.;95%
sodium tetrahydroborate
16940-66-2

sodium tetrahydroborate

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

sodium hydrotris(3-trifluoromethyl-5-methyl-1-pyrazolyl)borate

sodium hydrotris(3-trifluoromethyl-5-methyl-1-pyrazolyl)borate

Conditions
ConditionsYield
at 130℃; for 4h;92%
In kerosene byproducts: H2; 5 equiv. of substituted pyrazole, slow heating to 220°C until evolution of stoich. amt. of H2; cooling to 180°C, collection (filtration), washing (petroleum ether), drying (high vac.); elem. anal.;58%
copper(I) oxide

copper(I) oxide

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

[tris(3-trifluoromethyl-5-methylpyrazolate)tricopper(I)]
854763-47-6

[tris(3-trifluoromethyl-5-methylpyrazolate)tricopper(I)]

Conditions
ConditionsYield
With acetonitrile In benzene under N2; CH3CN added to mixt. of Cu2O and pyrazole derivative in benzene, mixt. refluxed for 12 h; cooled, filtered through Celite, filtrate evapd. under vac.; elem. anal.;92%
bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

methyl 2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetate

methyl 2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 18h;91%
1-ferrocenylethanol
1277-49-2

1-ferrocenylethanol

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

ferrocenyl(ethyl)-1N-(3-trifluoromethyl-5-methyl)pyrazole
654083-42-8

ferrocenyl(ethyl)-1N-(3-trifluoromethyl-5-methyl)pyrazole

Conditions
ConditionsYield
With tetrafluoroboric acid In dichloromethane; water addn. of aq. HBF4 to a mixt. of iron complex and heterocycle in CH2Cl2, stirring for 5 min; addn. of Et2O, water, ascorbic acid, sepn., washing org. phase with coldwater, evapn. drying over CaCl2;88%
5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

Ethyl 2-bromopropionate
535-11-5, 41978-69-2

Ethyl 2-bromopropionate

C10H13F3N2O2
1007487-64-0

C10H13F3N2O2

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran; N,N-dimethyl-formamide at 60℃; for 5h;88%
5-bromo-2-pyridylamine
1072-97-5

5-bromo-2-pyridylamine

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-amine
1415640-68-4

5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-amine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; cis-N,N'-dimethyl-1,2-diaminocyclohexane In 1,4-dioxane at 130℃; Schlenk technique; Inert atmosphere;88%
(S)-1-hydroxyethylferrocene

(S)-1-hydroxyethylferrocene

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(S)-(3-trifluoromethyl-5-methylpyrazolyl)-α-ethylferrrocene

(S)-(3-trifluoromethyl-5-methylpyrazolyl)-α-ethylferrrocene

Conditions
ConditionsYield
With tetrafluoroboric acid In dichloromethane; water at 22 - 25℃; for 0.0833333h; enantiospecific reaction;88%
5-bromo-4-methoxy-1,1,1-trifluoro-pent-3-en-2-one
502926-95-6

5-bromo-4-methoxy-1,1,1-trifluoro-pent-3-en-2-one

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

1-(3-methoxy-5-(trifluoromethyl)-2,3-dihydrofuran-3-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole

1-(3-methoxy-5-(trifluoromethyl)-2,3-dihydrofuran-3-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: 5-bromo-4-methoxy-1,1,1-trifluoro-pent-3-en-2-one In acetonitrile for 2h; Solvent; Reflux;
86%
5-bromo-4-(diethylamino)-1,1,1-trifluoropent-3-en-2-one

5-bromo-4-(diethylamino)-1,1,1-trifluoropent-3-en-2-one

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(E)-4-(diethylamino)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pent-3-en-2-one

(E)-4-(diethylamino)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pent-3-en-2-one

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: 5-bromo-4-(diethylamino)-1,1,1-trifluoropent-3-en-2-one In acetonitrile for 5h; Reflux;
85%
5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

2-bromobutyric acid ethyl ester
533-68-6

2-bromobutyric acid ethyl ester

C11H15F3N2O2

C11H15F3N2O2

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran; N,N-dimethyl-formamide at 60℃; for 5h;84%
(2S,4R)-4-(4-fluoro-2-trifluoromethylbenzenesulfonyl)-1-(1-trifluoromethylcyclopropanecarbonyl)pyrrolidine-2-carboxylic acid (1-cyanocyclopropyl)amide
1252637-02-7

(2S,4R)-4-(4-fluoro-2-trifluoromethylbenzenesulfonyl)-1-(1-trifluoromethylcyclopropanecarbonyl)pyrrolidine-2-carboxylic acid (1-cyanocyclopropyl)amide

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(2S,4R)-4-[4-(5-methyl-3-trifluoromethylpyrazol-1-yl)-2-trifluoromethylbenzenesulfonyl]-1-(1-trifluoromethylcyclopropanecarbonyl)pyrrolidine-2-carboxylic acid (1-cyanocyclopropyl)amide

(2S,4R)-4-[4-(5-methyl-3-trifluoromethylpyrazol-1-yl)-2-trifluoromethylbenzenesulfonyl]-1-(1-trifluoromethylcyclopropanecarbonyl)pyrrolidine-2-carboxylic acid (1-cyanocyclopropyl)amide

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl acetamide at 22℃; for 72h;84%
2-chloro-1-(1-(4-chloro-3-methoxyphenyl)piperidin-4-yl)ethanone
1018324-03-2

2-chloro-1-(1-(4-chloro-3-methoxyphenyl)piperidin-4-yl)ethanone

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

1-(1-(4-chloro-3-methoxyphenyl)piperidin-4-yl)-2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)ethanone
1018325-07-9

1-(1-(4-chloro-3-methoxyphenyl)piperidin-4-yl)-2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)ethanone

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; for 12h;81%
3-bromo-1-[1-(4-fluorophenyl)-5-isopropylpyrazol-4-yl]pyrrolidin-2-one
1613396-19-2

3-bromo-1-[1-(4-fluorophenyl)-5-isopropylpyrazol-4-yl]pyrrolidin-2-one

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

1-[1-(4-fluorophenyl)-5-isopropylpyrazol-4-yl]-3-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]pyrrolidin-2-one
1613395-15-5

1-[1-(4-fluorophenyl)-5-isopropylpyrazol-4-yl]-3-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]pyrrolidin-2-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1h;80%
C8H10BrF3O2

C8H10BrF3O2

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

5-methyl-1-(3-propoxy-5-(trifluoromethyl)-2,3-dihydrofuran-3-yl)-3-(trifluoromethyl)-1H-pyrazole

5-methyl-1-(3-propoxy-5-(trifluoromethyl)-2,3-dihydrofuran-3-yl)-3-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: C8H10BrF3O2 In acetonitrile for 2h; Reflux;
80%
6-bromopyridine-3-amine
13534-97-9

6-bromopyridine-3-amine

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

6-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]pyridin-3-amine
1006961-49-4

6-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]pyridin-3-amine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide In 1,4-dioxane at 130℃; Inert atmosphere; Schlenk technique;79%
4-oxo-4-phenyl-but-2-ynoic acid ethyl ester
54966-47-1

4-oxo-4-phenyl-but-2-ynoic acid ethyl ester

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-4-oxo-4-phenyl-butyric acid ethyl ester

2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-4-oxo-4-phenyl-butyric acid ethyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 16h;78%
5-bromo-1,1,1-trifluoro-4-(pyrrolidin-1-yl)pent-3-en-2-one

5-bromo-1,1,1-trifluoro-4-(pyrrolidin-1-yl)pent-3-en-2-one

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(E)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)-4-(pyrrolidin-1-yl)pent-3-en-2-one

(E)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)-4-(pyrrolidin-1-yl)pent-3-en-2-one

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: 5-bromo-1,1,1-trifluoro-4-(pyrrolidin-1-yl)pent-3-en-2-one In acetonitrile for 5h; Reflux;
78%
bis[bis(trimethylsilyl)amino]germanium(II)
59863-12-6

bis[bis(trimethylsilyl)amino]germanium(II)

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

[Ge(HC3N2(CF3)CH3)2]2

[Ge(HC3N2(CF3)CH3)2]2

Conditions
ConditionsYield
In hexane (under Ar, Schlenk); soln. of ligand in hexane added dropwise to soln. of Ge-compound in hexane at room temp.; treated with toluene, heated at 60°C, stored for 16 h at -20°C;77%
5-bromo-4-ethoxy-1,1,1-trifluoropent-3-en-2-one
910858-21-8

5-bromo-4-ethoxy-1,1,1-trifluoropent-3-en-2-one

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

1-(3-ethoxy-5-(trifluoromethyl)-2,3-dihydrofuran-3-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole

1-(3-ethoxy-5-(trifluoromethyl)-2,3-dihydrofuran-3-yl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: 5-bromo-4-ethoxy-1,1,1-trifluoropent-3-en-2-one In acetonitrile for 2h; Reflux;
76%
5-bromo-4-(dibutylamino)-1,1,1-trifluoropent-3-en-2-one

5-bromo-4-(dibutylamino)-1,1,1-trifluoropent-3-en-2-one

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(E)-4-(dibutylamino)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pent-3-en-2-one

(E)-4-(dibutylamino)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pent-3-en-2-one

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: 5-bromo-4-(dibutylamino)-1,1,1-trifluoropent-3-en-2-one In acetonitrile for 5h; Reflux;
73%
2-Fluorobenzaldehyde
446-52-6

2-Fluorobenzaldehyde

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

C12H7F3N2
1422280-85-0

C12H7F3N2

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 120℃; for 96h;71%
C10H13BrF3NO

C10H13BrF3NO

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(E)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)-4-(piperidin-1-yl)pent-3-en-2-one

(E)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)-4-(piperidin-1-yl)pent-3-en-2-one

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: C10H13BrF3NO In acetonitrile for 5h; Reflux;
71%
[Pt(P(C2H5)3)2(Cl)]2(2+)*2BF4(1-) = [Pt(P(C2H5)3)2(Cl)]2(BF4)2

[Pt(P(C2H5)3)2(Cl)]2(2+)*2BF4(1-) = [Pt(P(C2H5)3)2(Cl)]2(BF4)2

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

cis-chlorobis(triethylphosphine)(3-(trifluoromethyl)-5-methylpyrazole)platinum(II) tetrafluoroborate
84049-91-2

cis-chlorobis(triethylphosphine)(3-(trifluoromethyl)-5-methylpyrazole)platinum(II) tetrafluoroborate

Conditions
ConditionsYield
In acetone organic compd. added to Pt complex in acetone, stirred at room temp. for 5 h; evapn., recrystn. (CH2Cl2-pentane);70%
cis-dichlorobis(triethylphosphine)platinum(II)
13965-02-1, 14177-93-6, 15692-07-6

cis-dichlorobis(triethylphosphine)platinum(II)

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

cis-Pt(PEt3)2(NCMeCHC(CF3)N)2
84049-92-3

cis-Pt(PEt3)2(NCMeCHC(CF3)N)2

Conditions
ConditionsYield
With KOH In methanol KOH added to soln. of Pt complex and organci compd. in MeOH, stirred for 1 h; extn. (CH2Cl2), filtration, evapn., addition of pentane, cooling;70%
C6H7BrF3NO

C6H7BrF3NO

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

(E)-4-(dimethylamino)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pent-3-en-2-one

(E)-4-(dimethylamino)-1,1,1-trifluoro-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pent-3-en-2-one

Conditions
ConditionsYield
Stage #1: 5-methyl-3-trifluoromethyl-1H-pyrazole With potassium carbonate In acetonitrile at 20℃; for 0.333333h;
Stage #2: C6H7BrF3NO In acetonitrile for 5h; Reflux;
70%
ethyl 4-hydroxy-4-(4-methoxyphenyl)but-2-ynoate

ethyl 4-hydroxy-4-(4-methoxyphenyl)but-2-ynoate

5-methyl-3-trifluoromethyl-1H-pyrazole
10010-93-2

5-methyl-3-trifluoromethyl-1H-pyrazole

4-(4-methoxy-phenyl)-2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-4-oxo-butyric acid ethyl ester

4-(4-methoxy-phenyl)-2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-4-oxo-butyric acid ethyl ester

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 16h;68%

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