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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Ethyl 8-chloro-6-hydroxyoctanate

Cas:1070-65-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

8-Chloro-6-hydroxyoctanoic acid ethyl ester

Cas:1070-65-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 1070-65-1 with competitive price

Cas:1070-65-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

ETHYL 8-CHLORO-6-HYDROXYOCTANATE CAS:1070-65-1

Cas:1070-65-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Octanoic acid,8-chloro-6-hydroxy-, ethyl ester

Cas:1070-65-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Octanoic acid,8-chloro-6-hydroxy-, ethyl ester

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl8-chloro-6-hydroxyoctanate

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Octanoic acid,8-chloro-6-hydroxy-, ethyl ester

Cas:1070-65-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Ethyl 8-chloro-6-hydroxyoctanate

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing HuaNuo Bio-Pharmacuetical Co.,Ltd

Independent research and development of impurities, familiar with the market and impurity characteristics; We can ship out on the same day if the products are in stock; Focus on impurity development of new products in the market; Expert in customizi

Thioctic Acid Impurity 24

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

factory?direct?sale Application:healing drugs

Octanoic acid,8-chloro-6-hydroxy-, ethyl ester

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

8-Chloro-6-hydroxyoctanoic acid ethyl ester

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

ETHYL 8-CHLORO-6-HYDROXYOCTANATEAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

1070-65-1 Application:intermediate

Octanoic acid, 8-chloro-6-hydroxy-, ethyl ester

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

1070-65-1

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

The factory supplies Application:manufacturing supplies

Octanoicacid,8-chloro-6-hydroxy-,ethylester

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

factory?direct?sale Application:Fine chemical intermediates, used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents

Octanoic acid,8-chloro-6-hydroxy-, ethyl ester

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Other

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

Henan Sunlake Enterprise Corporation Our Advantages 1, Any inquiry about ch

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Run-Biotech Co., Ltd.

Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the ETHYL 8-CHLORO-6-HYDROXYOCTANATE, CAS:1070-65-1 with the most competitive price and t

ETHYL 8-CHLORO-6-HYDROXYOCTANATE

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Skyrun Industrial Co.,Ltd

Purity, Prompt shipment, Price Application:surface active agent

CSR160805-22261

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Topbatt Chemical Co., Ltd.

Topbatt Chemical Co., Ltd., Established in 2019, located in Shenzhen, Guangdong Province, is a Manufacturer and Trading company which specialized in fine chemicals like Pharmaceutical Reference Standards and Stable Isotopes. Our Stable Isotopes produ

Thioctic Acid Impurity 9

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

Ethyl8-chloro-6-hydroxyoctanate

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shenzhen Sumshine Biotech Co., Ltd.

1. Our staff are all biomedical related majors with rich experience in the pharmaceutical industry, and can provide you with more professional services.2. Our supplier has a good quality management system, and the quality of products is reliable and

Thioctic Acid Impurity 9

Cas:1070-65-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

adipinic acid monoethyl ester
626-86-8

adipinic acid monoethyl ester

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

Conditions
ConditionsYield
With thionyl chloride; 1,1,2,2-tetrachloroethane anschliessendes Behandeln mit Aethylen und Aluminiumchlorid und Behandeln der nach dem Versetzen mit wss.Salzsaeure erhaltenen nicht-waessrigen Phase des Reaktionsgemisches mit Natriumboranat in Aethanol;
ethyl 6-oxo-8-chlorooctanoate

ethyl 6-oxo-8-chlorooctanoate

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

Conditions
ConditionsYield
With sodium tetrahydroborate; tetrabutylammomium bromide; ammonia In 1,2-dichloro-ethane at 10 - 30℃; for 2h; Large scale;95 kg
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

6,8-dichlorooctanoic acid ethyl ester
1070-64-0

6,8-dichlorooctanoic acid ethyl ester

Conditions
ConditionsYield
With phosgene; N,N'-dimethylbenzylamine In 1,2-dichloro-ethane at 10 - 75℃; for 2.5h; Concentration; Solvent; Reagent/catalyst; Temperature;96.69%
With pyridine; thionyl chloride; benzene
With thionyl chloride In toluene at 100℃; for 5h; Reagent/catalyst; Solvent; Cooling with ice; Large scale;480 kg
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

(+)-8-chloro-6-hydroxy-octanoic acid
90435-60-2

(+)-8-chloro-6-hydroxy-octanoic acid

Conditions
ConditionsYield
With lithium hydroxide In ethanol Ambient temperature; Yield given;
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

N-(3-chloropropyl)-8-chloro-6-hydroxyoctylamine
120476-67-7

N-(3-chloropropyl)-8-chloro-6-hydroxyoctylamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

N-(3-chloropropyl)-8-chloro-6-hydroxyoctanamide
120476-66-6

N-(3-chloropropyl)-8-chloro-6-hydroxyoctanamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

N-(tert-butyloxycarbonyl)-N-(3-chloropropyl)-8-chloro-6-hydroxyoctylamine
120476-68-8

N-(tert-butyloxycarbonyl)-N-(3-chloropropyl)-8-chloro-6-hydroxyoctylamine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 77 percent / NaHCO3, NaCl / CHCl3; H2O / 2 h / Heating
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

(8-Chloro-6-hydroxy-octyl)-(3-chloro-propyl)-carbamic acid benzyl ester
120476-75-7

(8-Chloro-6-hydroxy-octyl)-(3-chloro-propyl)-carbamic acid benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 84 percent / 1M KOH / diethyl ether / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

N-(tert-butyloxycarbonyl)-N-(3-azidopropyl)-8-azido-6-hydroxyoctylamine
120476-69-9

N-(tert-butyloxycarbonyl)-N-(3-azidopropyl)-8-azido-6-hydroxyoctylamine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 77 percent / NaHCO3, NaCl / CHCl3; H2O / 2 h / Heating
5: 93 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

(8-Chloro-6-hydroxy-octyl)-(3-chloro-propyl)-carbamic acid 4-nitro-benzyl ester
120476-76-8

(8-Chloro-6-hydroxy-octyl)-(3-chloro-propyl)-carbamic acid 4-nitro-benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 70 percent / 1M KOH / diethyl ether / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

(8-Azido-6-hydroxy-octyl)-(3-azido-propyl)-carbamic acid benzyl ester
120476-77-9

(8-Azido-6-hydroxy-octyl)-(3-azido-propyl)-carbamic acid benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 84 percent / 1M KOH / diethyl ether / Ambient temperature
5: 65 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

Methanesulfonic acid 1-(2-azido-ethyl)-6-[(3-azido-propyl)-tert-butoxycarbonyl-amino]-hexyl ester
120476-79-1

Methanesulfonic acid 1-(2-azido-ethyl)-6-[(3-azido-propyl)-tert-butoxycarbonyl-amino]-hexyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 77 percent / NaHCO3, NaCl / CHCl3; H2O / 2 h / Heating
5: 93 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 92 percent / Et3N / CH2Cl2 / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

(8-Azido-6-hydroxy-octyl)-(3-azido-propyl)-carbamic acid 4-nitro-benzyl ester
120476-78-0

(8-Azido-6-hydroxy-octyl)-(3-azido-propyl)-carbamic acid 4-nitro-benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 70 percent / 1M KOH / diethyl ether / Ambient temperature
5: 88 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

N1-(3-Amino-propyl)-6-[(3aS,4S,6R,6aR)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-octane-1,8-diamine

N1-(3-Amino-propyl)-6-[(3aS,4S,6R,6aR)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-octane-1,8-diamine

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 70 percent / 1M KOH / diethyl ether / Ambient temperature
5: 88 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 99 percent / Et3N / CH2Cl2 / Ambient temperature
7: 43 percent / sodium methoxide / a) r.t., 48 h, b) 25 deg C, 12 h, sonication
8: 49 mg / H2, ethanol / 10percent Pd/C / methanol / 2585.7 Torr
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

Methanesulfonic acid 1-(2-azido-ethyl)-6-[(3-azido-propyl)-benzyloxycarbonyl-amino]-hexyl ester
120496-27-7

Methanesulfonic acid 1-(2-azido-ethyl)-6-[(3-azido-propyl)-benzyloxycarbonyl-amino]-hexyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 84 percent / 1M KOH / diethyl ether / Ambient temperature
5: 65 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 88 percent / Et3N / CH2Cl2 / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

Methanesulfonic acid 1-(2-azido-ethyl)-6-[(3-azido-propyl)-(4-nitro-benzyloxycarbonyl)-amino]-hexyl ester
120476-80-4

Methanesulfonic acid 1-(2-azido-ethyl)-6-[(3-azido-propyl)-(4-nitro-benzyloxycarbonyl)-amino]-hexyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 70 percent / 1M KOH / diethyl ether / Ambient temperature
5: 88 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 99 percent / Et3N / CH2Cl2 / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

{6-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-8-azido-octyl}-(3-azido-propyl)-carbamic acid tert-butyl ester

{6-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-8-azido-octyl}-(3-azido-propyl)-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 77 percent / NaHCO3, NaCl / CHCl3; H2O / 2 h / Heating
5: 93 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 92 percent / Et3N / CH2Cl2 / Ambient temperature
7: 28 percent / sodium methoxide / a) r.t., 48 h, b) 25 deg C, 12 h, sonication
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

{6-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-8-azido-octyl}-(3-azido-propyl)-carbamic acid benzyl ester

{6-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-8-azido-octyl}-(3-azido-propyl)-carbamic acid benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 84 percent / 1M KOH / diethyl ether / Ambient temperature
5: 65 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 88 percent / Et3N / CH2Cl2 / Ambient temperature
7: 80 percent / sodium methoxide / a) r.t., 48 h, b) 25 deg C, 12 h, sonication
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

S-(5'-deoxy-5'-adenosyl)-N-(3-aminopropyl)-8-amino-6-thiooctylamine formate salt

S-(5'-deoxy-5'-adenosyl)-N-(3-aminopropyl)-8-amino-6-thiooctylamine formate salt

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 70 percent / 1M KOH / diethyl ether / Ambient temperature
5: 88 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 99 percent / Et3N / CH2Cl2 / Ambient temperature
7: 43 percent / sodium methoxide / a) r.t., 48 h, b) 25 deg C, 12 h, sonication
8: 49 mg / H2, ethanol / 10percent Pd/C / methanol / 2585.7 Torr
9: 88percent formic acid / 3 h / Ambient temperature
View Scheme
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

{6-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-8-azido-octyl}-(3-azido-propyl)-carbamic acid 4-nitro-benzyl ester
120476-70-2

{6-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-8-azido-octyl}-(3-azido-propyl)-carbamic acid 4-nitro-benzyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: LiOH*H2O / aq. ethanol / Ambient temperature
2: 89 percent / N-methylmorpholine, 1-N-hydroxybenzotriazole, dicyclohexylcarbodiimide / dimethylformamide / 96 h / Ambient temperature
3: 75.4 percent / B2H6 / tetrahydrofuran / Ambient temperature
4: 70 percent / 1M KOH / diethyl ether / Ambient temperature
5: 88 percent / LiN3, LiI / dimethylformamide / 30 h / 60 °C
6: 99 percent / Et3N / CH2Cl2 / Ambient temperature
7: 43 percent / sodium methoxide / a) r.t., 48 h, b) 25 deg C, 12 h, sonication
View Scheme
vinyl propionate
105-38-4

vinyl propionate

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

A

C13H23ClO4

C13H23ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

C

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
C n/a
vinyl n-butyrate
123-20-6

vinyl n-butyrate

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

A

C14H25ClO4

C14H25ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

C

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
C n/a
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

acetic anhydride
108-24-7

acetic anhydride

A

C12H21ClO4

C12H21ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
butanoic acid anhydride
106-31-0

butanoic acid anhydride

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

A

C14H25ClO4

C14H25ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

2-Methylpropionic anhydride
97-72-3

2-Methylpropionic anhydride

A

C14H25ClO4

C14H25ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
pentanoic anhydride
2082-59-9

pentanoic anhydride

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

A

C15H27ClO4

C15H27ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
vinyl acetate
108-05-4

vinyl acetate

6-hydroxy-8-chlorooctanoic acid ethyl ester
1070-65-1

6-hydroxy-8-chlorooctanoic acid ethyl ester

A

C12H21ClO4

C12H21ClO4

B

ethyl (R)-8-chloro-6-hydroxyoctanoate
852383-82-5

ethyl (R)-8-chloro-6-hydroxyoctanoate

C

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
With Novozym 435 (lipase B from Candida antarctica) In di-isopropyl ether at 40℃; for 7h; Reagent/catalyst; Solvent; Time; Temperature; Resolution of racemate; Enzymatic reaction;A n/a
B n/a
C n/a

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