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ShiJiaZhuang Dowell Chemical Co.,Ltd.

Appearance:Colorless liquid Storage:well sealed in dry cool place Package:40KG/200KG/plastic coated metal pail/ISOTANK Application:used for medical &pesticide intermediate Transportation:BY SEA Port:Tianjin, Shanghai

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Metric Ton

FOB Price: $90.0 / 100.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product description: Product name 3,3-Dimethylbutyric acid CAS number 1070-83-3 Assay ≥99% Appearance Yellowish to colorless transparent liquid Capacity 200mt/year Application

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:100 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

tert-Butylacetic acid Synonyms 3,3-Dimethylbutyric acid; Butylaceticacid; 3,3-Dimethylbutyric acid; 3,3-dimethylbutanoic acid; 3,3-dimethylbutanoate; 3,3,3-TRIMETHYLPROPIONIC ACID CAS RN. 1070-83-3

3,3,3-TRIMETHYLPROPIONIC ACID

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--1070-83-3--3,3-Dimethylbutyric acid in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business re

TIANFUCHEM--1070-83-3--3,3-Dimethylbutyric acid in stock

Cas:1070-83-3

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct sale CAS 1070-83-3 with best quality

Cas:1070-83-3

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: 3,3-Dimethylbutyric acid Molecular Formula: C6H12O2 Molecular Weight: 116.16 CAS: 1070-83-3 Structural Formula: Appearance:Colorless clear liquid Storage:Preserve in well-closed, light-resistant and airtight containers. Package:25kg/dr

3,3-Dimethylbutyric acid CAS:1070-83-3

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:Light yellow to colorless transparent liquid Storage:R.T Package:25kg/drum Application:Pharmaceutical intermediate Transportation:Express/Sea/Air Port:Any port in China

tert-Butylaceticacid 3,3-Dimethylbutyric acid cas 1070-83-3

Cas:1070-83-3

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Butanoicacid, 3,3-dimethyl- 1070-83-3

Cas:1070-83-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $90.0 / 95.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3,3-Dimethylbutyric acid CAS:1070-83-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

3,3-Dimethylbutyric acid CAS:1070-83-3

Cas:1070-83-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanoicacid, 3,3-dimethyl-

Cas:1070-83-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Butanoicacid, 3,3-dimethyl-/ LIDE PHARMA- Factory supply / Best price

Cas:1070-83-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3,3-Dimethylbutyric acid CAS:1070-83-3

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:1070-83-3

Cas:1070-83-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,3-DiMethylbutyric acid

Cas:1070-83-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 3,3-Dimethyl Butyric Acid CAS No.: 1070-83-3 Molecule Formula:C6H11O2 Molecule Weight:115.15 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING

Lower Price 3,3-Dimethyl Butyric Acid

Cas:1070-83-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $666.0 / 777.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

Appearance:powder or granule ( refer to COA) Application:Librium, Valium

Factory Supply tert-Butylacetic acid

Cas:1070-83-3

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

3,3-Dimethylbutyric Acid

Cas:1070-83-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

3,3-Dimethylbutyric acid

Cas:1070-83-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Synthetic route

3,3-dimethylbutyrylaldehyde
2987-16-8

3,3-dimethylbutyrylaldehyde

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With dihydrogen peroxide; 7-(trifluoromethyl)-1,10-ethyleneisoalloxazinium chloride In water; acetonitrile at 85℃; for 18h;98%
With oxygen; copper(II) acetate monohydrate; cobalt(II) diacetate tetrahydrate In water at 20℃; under 760.051 Torr; for 3h;95%
With N-hydroxyphthalimide; oxygen In acetonitrile at 30℃; for 3h; Schlenk technique;83%
With N-hydroxyphthalimide; oxygen In acetonitrile at 30℃; under 760.051 Torr; for 3h; Catalytic behavior; Solvent; Schlenk technique;83%
With dihydrogen peroxide; benzeneseleninic acid In tetrahydrofuran for 2h; Heating;76 % Chromat.
1,1-Dichloroethylene
75-35-4

1,1-Dichloroethylene

tert-butyl alcohol
75-65-0

tert-butyl alcohol

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With sulfuric acid at 2℃; for 0.75h;90%
With sulfuric acid; boron trifluoride
(i) H2SO4, BF3, (ii) aq. H2SO4; Multistep reaction;
With sulfuric acid at 0 - 5℃; for 1.25h;
3,3-dimethyl-1-butynyl tosylate
90893-24-6

3,3-dimethyl-1-butynyl tosylate

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With hydrogenchloride In acetonitrile for 24h; Heating;90%
With hydrogenchloride In acetonitrile for 24h; Mechanism; Heating; other alkynyl tosylate;90%
3,3-dimethylbutanol
624-95-3

3,3-dimethylbutanol

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With potassium hydroxide; oxygen In 1,2-dimethoxyethane at 20℃; for 14h;85%
With alkaline KMNO4 at 4℃;
tertiary butyl chloride
507-20-0

tertiary butyl chloride

1,1-Dichloroethylene
75-35-4

1,1-Dichloroethylene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With boron trifluoride In sulfuric acid 1.) 5-15 deg C, 3 h, 2.) 10 deg C, 0.5 h;81%
With sulfuric acid at 6℃; for 2h;77%
(i) H2SO4, BF3, (ii) aq. H2SO4; Multistep reaction;
neo-hexylboronic acid
140614-17-1

neo-hexylboronic acid

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With chromium(VI) oxide In dichloromethane; acetic acid at 25℃; for 12h;80%
2-((Z)-3,3-Dimethyl-1-trimethylgermanyl-but-1-enyl)-[1,3,2]dioxaborinane

2-((Z)-3,3-Dimethyl-1-trimethylgermanyl-but-1-enyl)-[1,3,2]dioxaborinane

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide In tetrahydrofuran; methanol at 20℃; for 4h;68%
tert-butyl methyl ether
1634-04-4

tert-butyl methyl ether

1,1-Dichloroethylene
75-35-4

1,1-Dichloroethylene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With sulfuric acid at 5℃; for 0.5h;55%
3,3-dimethylbutanol
624-95-3

3,3-dimethylbutanol

A

3,3-dimethylbutyrylaldehyde
2987-16-8

3,3-dimethylbutyrylaldehyde

B

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With copper(II) oxide at 300℃; Gas phase;A n/a
B 30%
4,4-dimethyl-pentan-2-one
590-50-1

4,4-dimethyl-pentan-2-one

A

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

B

acetic acid
64-19-7

acetic acid

C

Trimethylacetic acid
75-98-9

Trimethylacetic acid

Conditions
ConditionsYield
With oxygen; H5PV2Mo10O40(1,11) In acetonitrile at 60℃; under 750.06 Torr; for 24h;A 20%
B 16%
C 20%
tetrachloromethane
56-23-5

tetrachloromethane

6,6,7,7-tetrakis-(4,4-dimethyl-pent-1-ynyl)-2,2,11,11-tetramethyl-dodeca-4,8-diyne

6,6,7,7-tetrakis-(4,4-dimethyl-pent-1-ynyl)-2,2,11,11-tetramethyl-dodeca-4,8-diyne

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
bei der Ozonspaltung;
2,2,4-trimethylpentane
540-84-1

2,2,4-trimethylpentane

A

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

B

Trimethylacetic acid
75-98-9

Trimethylacetic acid

Conditions
ConditionsYield
With nitric acid
4,4-dimethyl-pentan-2-one
590-50-1

4,4-dimethyl-pentan-2-one

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With alkaline Ca(OCl)2
With sodium hypobromide
With sodium hypobromide
2-(2,2-dimethyl-propyl)-buta-1,3-diene
5732-01-4

2-(2,2-dimethyl-propyl)-buta-1,3-diene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With potassium permanganate
1,1,1-trichloro-3,3-dimethyl-butane
125484-47-1

1,1,1-trichloro-3,3-dimethyl-butane

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With water at 275℃;
1,1-dichloro-3,3-dimethyl-1-butene
32363-94-3

1,1-dichloro-3,3-dimethyl-1-butene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With water at 275℃;
2-(tert-butyl)malonic acid
4379-33-3

2-(tert-butyl)malonic acid

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

ethyl t-butylcyanoacetate
21954-81-4

ethyl t-butylcyanoacetate

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With hydrogen bromide
tert-butylmalonic acid diethyl ester
759-24-0

tert-butylmalonic acid diethyl ester

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With potassium hydroxide
Multi-step reaction with 2 steps
1: alcoholic KOH
View Scheme
4-t-amylphenol
80-46-6

4-t-amylphenol

A

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

B

3,3-dimethyl-2-oxopentanoic acid
34906-91-7

3,3-dimethyl-2-oxopentanoic acid

Conditions
ConditionsYield
With potassium permanganate Oxydation;
1,1-dimethylpropylmagnesium chloride
28276-08-6

1,1-dimethylpropylmagnesium chloride

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

ethene
74-85-1

ethene

tertiary butyl chloride
507-20-0

tertiary butyl chloride

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
Multistep reaction;
neopentyl chloride
753-89-9

neopentyl chloride

carbon dioxide
124-38-9

carbon dioxide

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
(i) Li, Et2O, (ii) /BRN= 1900390/, (iii) aq. HCl; Multistep reaction;
1,1-Dichloroethylene
75-35-4

1,1-Dichloroethylene

2,6-di-tert-butyl-4-methoxymethylene-phenol
87-97-8

2,6-di-tert-butyl-4-methoxymethylene-phenol

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With sulfuric acid at 5℃;
1,2,3-trichloro-5,5-dimethyl-hex-2-ene
26653-41-8

1,2,3-trichloro-5,5-dimethyl-hex-2-ene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With potassium hydroxide; potassium permanganate
N-(3,3-Dimethyl-1-tosyl-1-butenyl)-formamid
38926-93-1

N-(3,3-Dimethyl-1-tosyl-1-butenyl)-formamid

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With hydrogenchloride
carbon dioxide
124-38-9

carbon dioxide

2,2-dimethylpropylmagnesium chloride
13132-23-5

2,2-dimethylpropylmagnesium chloride

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With diethyl ether
(i) MnCl2, THF, (ii) /BRN= 1900390/; Multistep reaction;
1,1-Dichloroethylene
75-35-4

1,1-Dichloroethylene

isobutene
115-11-7

isobutene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
(i) H2SO4, BF3, (ii) aq. H2SO4; Multistep reaction;
tert-butylethylene
558-37-2

tert-butylethylene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
Yield given. Multistep reaction;
Multi-step reaction with 3 steps
1: HBr
2: potassium acetate / und man verseift das erhaltene Acetat durch Erhitzen mit gepulvertem Kali auf 200grad
View Scheme
(E)-1-(diethoxymethylsilyl)-3,3-dimethyl-1-butene
89984-54-3

(E)-1-(diethoxymethylsilyl)-3,3-dimethyl-1-butene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

Conditions
ConditionsYield
With potassium hydrogen bifluoride; dihydrogen peroxide In acetic anhydride; N,N-dimethyl-formamide for 20h; Ambient temperature; Yield given;
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

(S)-3-(benzyloxy)-2-isocyano-N-methoxy-N-methylpropanamide
1381872-57-6

(S)-3-(benzyloxy)-2-isocyano-N-methoxy-N-methylpropanamide

Boc-L-phenylalaninal
72155-45-4

Boc-L-phenylalaninal

C33H47N3O8
1381872-77-0

C33H47N3O8

Conditions
ConditionsYield
In dichloromethane Passerini reaction;100%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

(2R)-2-amino-N-(1-cyanocyclopropyl)-3-[4-(2-pyridyl)piperazin-1-yl]sulfonyl-propanamide

(2R)-2-amino-N-(1-cyanocyclopropyl)-3-[4-(2-pyridyl)piperazin-1-yl]sulfonyl-propanamide

N-[(1R)-1-[(1-cyanocyclopropyl)carbamoyl]-2-[4-(pyridin-2-yl)piperazine-1-sulfonyl]ethyl]-3,3-dimethylbutanamide

N-[(1R)-1-[(1-cyanocyclopropyl)carbamoyl]-2-[4-(pyridin-2-yl)piperazine-1-sulfonyl]ethyl]-3,3-dimethylbutanamide

Conditions
ConditionsYield
Stage #1: tert-Butylacetic acid With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0℃; for 0.25h;
Stage #2: (2R)-2-amino-N-(1-cyanocyclopropyl)-3-[4-(2-pyridyl)piperazin-1-yl]sulfonyl-propanamide With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;
100%
methanol
67-56-1

methanol

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

methyl 3,3-dimethylbutyrate
10250-48-3

methyl 3,3-dimethylbutyrate

Conditions
ConditionsYield
Heating;98%
With sulfuric acid
(i) SOCl2, (ii) /BRN= 1098229/; Multistep reaction;
With sulfuric acid at 75℃; for 2h; Yield given;
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

C24H30Cl3N3O
1427714-34-8

C24H30Cl3N3O

C30H40Cl3N3O2
1427714-36-0

C30H40Cl3N3O2

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 25℃; for 18h;98%
oxalyl dichloride
79-37-8

oxalyl dichloride

Methyl (+/-)-3-oxo-8-[3-(1-oxo-pyridin-2-yl)amino-1-propyloxy]-2-(4-trifluoromethylbenzyl)-2,3,4.5-tetrahydro-1H-2-benzazepine-4-acetate
205677-63-0

Methyl (+/-)-3-oxo-8-[3-(1-oxo-pyridin-2-yl)amino-1-propyloxy]-2-(4-trifluoromethylbenzyl)-2,3,4.5-tetrahydro-1H-2-benzazepine-4-acetate

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

methyl (+/-)-3-oxo-8-[3-[N-(1-oxo-pyridin-2-yl)-N-(tert-butylacetyl)amino]-1-propyloxy]-2-(4-trifluoromethylbenzyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate
205677-66-3

methyl (+/-)-3-oxo-8-[3-[N-(1-oxo-pyridin-2-yl)-N-(tert-butylacetyl)amino]-1-propyloxy]-2-(4-trifluoromethylbenzyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate

Conditions
ConditionsYield
With triethylamine In dichloromethane; N,N-dimethyl-formamide97%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

2,2-dimethylpropane
463-82-1

2,2-dimethylpropane

Conditions
ConditionsYield
With hydrogen; silica gel; palladium at 330℃;96%
1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

3,3-dimethylbutyric acid 2,5-dioxopyrrolidin-1-yl ester

3,3-dimethylbutyric acid 2,5-dioxopyrrolidin-1-yl ester

Conditions
ConditionsYield
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane at 25℃; for 14h; Acylation;96%
With dicyclohexyl-carbodiimide In tetrahydrofuran for 12h;49%
With 1,2-dichloro-ethane In dichloromethane for 3h;
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

zinc(II) oxide

zinc(II) oxide

tetrazinc μ4-oxohexa-mu.-3,3-dimethylbutanoate

tetrazinc μ4-oxohexa-mu.-3,3-dimethylbutanoate

Conditions
ConditionsYield
In toluene mixt. 3,3-dimethylbutanoic acid (6 equiv.) and zinc oxide (4 equiv.) and toluene heated with stirring for 3 h (water removed); product filtered, solvent removed from filtrate, purified by recrystn.;elem. anal.;96%
titanium(IV) isopropylate
546-68-9

titanium(IV) isopropylate

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

[Ti8O8(tert-butyl acetate)16]

[Ti8O8(tert-butyl acetate)16]

Conditions
ConditionsYield
In acetonitrile at 100℃; for 72h; Inert atmosphere; High pressure;96%
In toluene Ti-isopropoxide added dropwise to soln. of (CH3)3CCH2COOH in toluene, mixt. stirred for 12 h; crystn. on slow evapn. under Ar for 2-3 d; elem. anal.;24.2%
tetrahydrofuran
109-99-9

tetrahydrofuran

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

ethyl 2-(2-bromophenyl)-2-diazoacetate
1398179-24-2

ethyl 2-(2-bromophenyl)-2-diazoacetate

4-(1-(2-bromophenyl)-2-ethoxy-2-oxoethoxy)butyl 3,3-dimethylbutanoate

4-(1-(2-bromophenyl)-2-ethoxy-2-oxoethoxy)butyl 3,3-dimethylbutanoate

Conditions
ConditionsYield
With potassium carbonate at 80℃; for 12h; Inert atmosphere; Schlenk technique;96%
(S)-2-amino-4-benzyloxy-butyric acid methyl ester

(S)-2-amino-4-benzyloxy-butyric acid methyl ester

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

methyl (S)-2-(3,3-dimethylbutanoylamino)-4-(phenylmethoxy)butyrate

methyl (S)-2-(3,3-dimethylbutanoylamino)-4-(phenylmethoxy)butyrate

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane; water95%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride
7524-50-7

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

(S)-2-(3,3-dimethylbutyrylamino)-3-phenylpropionic acid methyl ester

(S)-2-(3,3-dimethylbutyrylamino)-3-phenylpropionic acid methyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 24h;95%
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 24h;95%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

2,4-bis(tert-butyl)acetoacetic acid
40348-20-7

2,4-bis(tert-butyl)acetoacetic acid

Conditions
ConditionsYield
Stage #1: tert-Butylacetic acid With trifluorormethanesulfonic acid; trifluoroacetic anhydride at 60 - 65℃;
Stage #2: With water Cooling;
94%
Multi-step reaction with 3 steps
1: (i) LDA, (ii) /BRN= 1209232/
2: 230 - 240 °C
3: aq. HCl
View Scheme
Multi-step reaction with 2 steps
1: trifluorormethanesulfonic acid / 2.5 h / 65 °C
2: water / 0.5 h / Cooling with ice
View Scheme
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

4-methoxycarbonyl aniline
619-45-4

4-methoxycarbonyl aniline

4-(3,3-dimethylbutanamido)benzoic acid
851203-04-8

4-(3,3-dimethylbutanamido)benzoic acid

Conditions
ConditionsYield
Stage #1: tert-Butylacetic acid; 4-methoxycarbonyl aniline With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 20℃; for 24h;
Stage #2: With ethanol; water; lithium hydroxide In tetrahydrofuran at 65℃; for 3h;
94%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
582-52-5

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

1,2;5,6-di-O-(1-methylethylidene)-α-D-glucofuranosyl 3,3-dimethyl butanoate
171734-65-9

1,2;5,6-di-O-(1-methylethylidene)-α-D-glucofuranosyl 3,3-dimethyl butanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃;93%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

(2S,4R)-allyl 4-(2-((1R,3R)-3-((tert-butoxycarbonyl)(methyl)amino)-1-hydroxy-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate

(2S,4R)-allyl 4-(2-((1R,3R)-3-((tert-butoxycarbonyl)(methyl)amino)-1-hydroxy-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate

(2S,4R)-allyl 4-(2-((1R,3R)-3-((tert-butoxycarbonyl)(methyl)amino)-4-methyl-1-((3,3-dimethylbutanoyl)oxy)pentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate

(2S,4R)-allyl 4-(2-((1R,3R)-3-((tert-butoxycarbonyl)(methyl)amino)-4-methyl-1-((3,3-dimethylbutanoyl)oxy)pentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate

Conditions
ConditionsYield
Stage #1: tert-Butylacetic acid With dmap; diisopropyl-carbodiimide In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;
Stage #2: (2S,4R)-allyl 4-(2-((1R,3R)-3-((tert-butoxycarbonyl)(methyl)amino)-1-hydroxy-4-methylpentyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate In dichloromethane Inert atmosphere;
93%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride
16652-71-4

benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride

(S)-benzyl 1-(3,3-dimethylbutanoyl)pyrrolidine-2-carboxylate
92010-16-7

(S)-benzyl 1-(3,3-dimethylbutanoyl)pyrrolidine-2-carboxylate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane Ambient temperature;92%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;74%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

O-diphenylmethyl 2,2,2-trichloroacetimidate
100865-93-8

O-diphenylmethyl 2,2,2-trichloroacetimidate

benzhydryl 3,3-dimethylbutanoate
1632280-43-3

benzhydryl 3,3-dimethylbutanoate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 18h; Inert atmosphere;92%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

aniline
62-53-3

aniline

N-(3,3-dimethylbutyl)aniline

N-(3,3-dimethylbutyl)aniline

Conditions
ConditionsYield
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; phenylsilane; 1,2-bis-(diphenylphosphino)ethane In dibutyl ether at 60℃; for 18h; Schlenk technique; Inert atmosphere;92%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

(2S,4R)-benzyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
62147-27-7

(2S,4R)-benzyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride

benzyl (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylate

benzyl (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylate

Conditions
ConditionsYield
Stage #1: tert-Butylacetic acid; (2S,4R)-benzyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.0833333h;
Stage #2: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.5h;
91%
chlorosulfuric acid chloromethyl ester
49715-04-0

chlorosulfuric acid chloromethyl ester

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

chloromethyl 3,3-dimethylbutanoate
114670-75-6

chloromethyl 3,3-dimethylbutanoate

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydrogensulfate In dichloromethane; water at 0 - 20℃; for 16h;91%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

[Ti(μ-ONep)(ONep)3]2

[Ti(μ-ONep)(ONep)3]2

3Ti(4+)*O(2-)*2(CH3)3CCH2COO(1-)*8(CH3)3CCH2O(1-)=[Ti3O(OOCCH2C(CH3)3)2(OCH2C(CH3)3)8]

3Ti(4+)*O(2-)*2(CH3)3CCH2COO(1-)*8(CH3)3CCH2O(1-)=[Ti3O(OOCCH2C(CH3)3)2(OCH2C(CH3)3)8]

Conditions
ConditionsYield
In toluene dry inert atm.; equimolar ratio, stirring (12 h); concn., evapn., crystn., drying; elem. anal.;90.9%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

1,3-di-O-benzyl-2-O-(2,3,4-tri-O-benzyl-β-D-galactopyranosyl)-glycerol
444808-94-0

1,3-di-O-benzyl-2-O-(2,3,4-tri-O-benzyl-β-D-galactopyranosyl)-glycerol

1,3-di-O-benzyl-2-O-(2,3,4-tri-O-benzyl-6-O-(3,3-dimethylbutanoyl)-β-D-galactopyranosyl)-glycerol

1,3-di-O-benzyl-2-O-(2,3,4-tri-O-benzyl-6-O-(3,3-dimethylbutanoyl)-β-D-galactopyranosyl)-glycerol

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃;90%
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

2,3,4,5,6-pentafluorophenol
771-61-9

2,3,4,5,6-pentafluorophenol

3,3-dimethylbutyric acid pentafluorophenyl ester
957049-08-0

3,3-dimethylbutyric acid pentafluorophenyl ester

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In 1,4-dioxane for 12h;90%
copper(II) carbonate

copper(II) carbonate

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

[Cu2(3,3-dimethylbutyric acid)4(3,3-dimethylbutyric acid)2]

[Cu2(3,3-dimethylbutyric acid)4(3,3-dimethylbutyric acid)2]

Conditions
ConditionsYield
In water; acetone90%
2-Acetylthiophene
88-15-3

2-Acetylthiophene

tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

5,5-Dimethyl-1-(thiophen-2-yl)hexane-1,3-dione

5,5-Dimethyl-1-(thiophen-2-yl)hexane-1,3-dione

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; trifluoroacetic anhydride In dichloromethane at 20℃; for 24h;90%
In dichloromethane at 20℃; for 3h;
tert-Butylacetic acid
1070-83-3

tert-Butylacetic acid

2,2,2,-trichloroethoxycarbonyl azide

2,2,2,-trichloroethoxycarbonyl azide

2,2,2-trichloroethyl neopentylcarbamate

2,2,2-trichloroethyl neopentylcarbamate

Conditions
ConditionsYield
With dmap; copper diacetate In acetonitrile at 80℃; for 3h; Schlenk technique; Sealed tube;90%

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