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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Mosapride Citrate supplier in China

Cas:112885-42-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

High quality Mosapride Citrate CAS NO.112885-42-4

Cas:112885-42-4

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Mosapride citrate Cas 112885-42-4 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to yellowish crystalline powder Storage:Store at RT Package

Factory supply high quality Mosapride citrate Cas 112885-42-4 with best price

Cas:112885-42-4

Min.Order:1 Kilogram

FOB Price: $440.0 / 445.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Mosapride Citrate

Cas:112885-42-4

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Mosapride citrate 112885-42-4 GMP Manufacturer

Cas:112885-42-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

Mosapride citrate

Cas:112885-42-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

GMP Factory supply best price ,provide free sample High purity on USP/EP standard Our company SINOWAY advantages : 1) ISO 9001:2015 & SGS audited supplier 2) Established in 1987, exported 35 years in pharmaceutical /cosmetic raw materials

Mosapride citrate

Cas:112885-42-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent out in 24 hours after payment.Tracking number available 2) Secure and disc

Mosapride citrate CAS:112885-42-4

Cas:112885-42-4

Min.Order:1 Kilogram

FOB Price: $150.0 / 200.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: Mosapride citrate Synonyms: MOSAPRIDE CITRATE;(+-)-4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)b;as4370;benzamide,4-amino-5-chloro-2-ethoxy-n-((4-((4-fl

Mosapride citrate cas 112885-42-4

Cas:112885-42-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 112885-42-4 with competitive price

Cas:112885-42-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: (+-)-4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)b CAS:112885-42-4 MF: C27H37ClFN3O12 Appearance:White Powder Storage:Store in cool and dry place, away from sun light. Package:25kg Application:APIs Transportation:By

(+-)-4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)b

Cas:112885-42-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Mosapride citrate 112885-42-4

Cas:112885-42-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Mosapride citrate CAS:112885-42-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

Mosapride citrate CAS:112885-42-4

Cas:112885-42-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Mosapride citrate

Cas:112885-42-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Mosapride Citrate manufacturer with low price

Cas:112885-42-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Mosapride citrate

Cas:112885-42-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

Mosapride citrate

Cas:112885-42-4

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

conforms to in-house standard ,have GMP Appearance:White or off white crystalline powder Storage:Room temperature Package:25kg/drum Application:used in medicine Transportation:BY SEA,AIR OR EXPRESS(TNT,DHL,FEDEX OR EMS) Port:Hangzhou or Shanghai,C

Mosapride citrate

Cas:112885-42-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Mosapride citrate 112885-42-4

Cas:112885-42-4

Min.Order:100 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Mosapride citrate

Cas:112885-42-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Mosapride citrate

Cas:112885-42-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

MOSAPRIDE CITRATE

Cas:112885-42-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Mosapride citrate

Cas:112885-42-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Mosapride citrate

Cas:112885-42-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Mosapride Citrate

Cas:112885-42-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Mosapride CitrateAppearance:Colorless transparent liquid Storage:Keep away of light, cool place Package:according to customers' requirements Application:pharmaceutical intermediates Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(F

Mosapride Citrate

Cas:112885-42-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Mosapride citrate

Cas:112885-42-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

In Bulk SupplyMosapride citrate

Cas:112885-42-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Mosapridecitrate

Cas:112885-42-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Synthetic route

mosapride
112885-41-3

mosapride

citric acid
77-92-9

citric acid

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
In ethanol; water at 70 - 75℃; for 0.5h; Temperature;97.2%
at 80 - 110℃; for 0.5h; Product distribution / selectivity;95.45%
In ethanol; water at 50℃; for 1h; Solvent; Temperature;94.7%
In ethanol; water at 20℃; for 2h;89%
4-acetylamino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]methyl]benzamide
112885-34-4

4-acetylamino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]methyl]benzamide

citric acid
77-92-9

citric acid

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
In methanol; water at 50 - 65℃; Temperature;88.7%
(RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluoro-benzyl)-2-morpholinyl]-methyl}-benzamide dihydrochloride

(RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluoro-benzyl)-2-morpholinyl]-methyl}-benzamide dihydrochloride

citric acid
77-92-9

citric acid

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Stage #1: (RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluoro-benzyl)-2-morpholinyl]-methyl}-benzamide dihydrochloride With sodium hydroxide In dichloromethane; water for 0.5h; Heating / reflux;
Stage #2: citric acid In water at 0℃; for 0.5h; Heating / reflux;
88%
mosapride
112885-41-3

mosapride

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
With citric acid In water at 0℃; Heating / reflux;86%
(RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluoro-benzyl)-2-morpholinyl]-methyl}-benzamide trifluoroacetate
636582-76-8

(RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluoro-benzyl)-2-morpholinyl]-methyl}-benzamide trifluoroacetate

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Stage #1: (RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluoro-benzyl)-2-morpholinyl]-methyl}-benzamide trifluoroacetate With sodium hydroxide In dichloromethane; water
Stage #2: With citric acid In water
83%
4-(4-fluorobenzyl)-2-aminomethylmorpholine sulfate

4-(4-fluorobenzyl)-2-aminomethylmorpholine sulfate

C13H16ClNO4

C13H16ClNO4

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
2: methanol; water / 50 - 65 °C
View Scheme
4-(4-fluorobenzyl)-2-aminomethylmorpholine hydrochloride

4-(4-fluorobenzyl)-2-aminomethylmorpholine hydrochloride

C13H16ClNO4

C13H16ClNO4

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
2: methanol; water / 50 - 65 °C
View Scheme
4-(4-fluorobenzyl)-2-aminomethylmorpholine phosphate

4-(4-fluorobenzyl)-2-aminomethylmorpholine phosphate

C13H16ClNO4

C13H16ClNO4

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
2: methanol; water / 50 - 65 °C
View Scheme
C12H17FN2O4S

C12H17FN2O4S

C13H16ClNO4

C13H16ClNO4

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
2: methanol; water / 50 - 65 °C
View Scheme
sodium p-aminosalicylate
133-10-8

sodium p-aminosalicylate

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: water / 4 h / 45 °C
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
3: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
5: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 5 steps
1: water / 4 h / 45 °C
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
3: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
5: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 5 steps
1: water / 4 h / 45 °C
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
3: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
5: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 5 steps
1: water / 4 h / 45 °C
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
3: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
5: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 5 steps
1: water / 4 h / 45 °C
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
3: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
5: methanol; water / 50 - 65 °C
View Scheme
4-acetamidosalicylic acid
50-86-2

4-acetamidosalicylic acid

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4: methanol; water / 50 - 65 °C
View Scheme
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 65 °C
2.1: 3 h / 70 - 80 °C
2.2: 2.5 h / 70 - 145 °C
2.3: 1.5 h
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 65 °C
2.1: 3 h / 70 - 80 °C
2.2: 2.5 h / 70 - 145 °C
2.3: 1.5 h
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 65 °C
2.1: 3 h / 70 - 80 °C
2.2: 2.5 h / 70 - 145 °C
2.3: 1.5 h
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 65 °C
2.1: 3 h / 70 - 80 °C
2.2: 2.5 h / 70 - 145 °C
2.3: 2 h
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / methanol / 4 h / 65 °C
2.1: 3 h / 70 - 80 °C
2.2: 2.5 h / 70 - 145 °C
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
4.1: methanol; water / 50 - 65 °C
View Scheme
4-acetylamino-2-ethoxy-benzoic acid ethyl ester
2486-67-1

4-acetylamino-2-ethoxy-benzoic acid ethyl ester

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h / 80 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3: methanol; water / 50 - 65 °C
View Scheme
C13H16ClNO4

C13H16ClNO4

2-aminomethyl-4-(4-fluoro-benzyl) morpholine
112914-13-3

2-aminomethyl-4-(4-fluoro-benzyl) morpholine

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
2: methanol; water / 50 - 65 °C
View Scheme
2-(4-fluoro-benzyl-amino)-ethanol
22116-33-2

2-(4-fluoro-benzyl-amino)-ethanol

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 3 h / 70 - 80 °C
1.2: 2.5 h / 70 - 145 °C
1.3: 1.5 h
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1.1: 3 h / 70 - 80 °C
1.2: 2.5 h / 70 - 145 °C
1.3: 1.5 h
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1.1: 3 h / 70 - 80 °C
1.2: 2.5 h / 70 - 145 °C
1.3: 1.5 h
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1.1: 3 h / 70 - 80 °C
1.2: 2.5 h / 70 - 145 °C
1.3: 2 h
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3.1: methanol; water / 50 - 65 °C
View Scheme
Multi-step reaction with 3 steps
1.1: 3 h / 70 - 80 °C
1.2: 2.5 h / 70 - 145 °C
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap; triethylamine / dichloromethane / 1 h / -10 - -5 °C
3.1: methanol; water / 50 - 65 °C
View Scheme
2-fluoro-4-nitro-benzoic acid methyl ester
392-09-6

2-fluoro-4-nitro-benzoic acid methyl ester

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: ethanol / 4 h / 40 °C
2: iron(III) chloride; N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 50 °C
3: N,N-dimethyl-formamide / 6 h / 100 °C
4: iron; ammonium chloride / ethanol; water / 5 h / Reflux
5: ethanol; water / 2 h / 20 °C
View Scheme
Multi-step reaction with 5 steps
1: ethanol / 4 h / 40 °C
2: iron(III) chloride; N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 50 °C
3: triethylamine / N,N-dimethyl-formamide / 6 h / 100 °C
4: iron; ammonium chloride / ethanol; water / 5 h / Reflux
5: ethanol; water / 2 h / 20 °C
View Scheme
2-fluoro-4-nitrobenzoic acid
403-24-7

2-fluoro-4-nitrobenzoic acid

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: sulfuric acid / 4 h / Reflux
2: ethanol / 4 h / 40 °C
3: iron(III) chloride; N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 50 °C
4: N,N-dimethyl-formamide / 6 h / 100 °C
5: iron; ammonium chloride / ethanol; water / 5 h / Reflux
6: ethanol; water / 2 h / 20 °C
View Scheme
Multi-step reaction with 6 steps
1: sulfuric acid / 4 h / Reflux
2: ethanol / 4 h / 40 °C
3: iron(III) chloride; N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 50 °C
4: triethylamine / N,N-dimethyl-formamide / 6 h / 100 °C
5: iron; ammonium chloride / ethanol; water / 5 h / Reflux
6: ethanol; water / 2 h / 20 °C
View Scheme
methyl 2-ethoxy-4-nitrobenzoate
24091-87-0

methyl 2-ethoxy-4-nitrobenzoate

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: iron(III) chloride; N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 50 °C
2: N,N-dimethyl-formamide / 6 h / 100 °C
3: iron; ammonium chloride / ethanol; water / 5 h / Reflux
4: ethanol; water / 2 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: iron(III) chloride; N-chloro-succinimide / N,N-dimethyl-formamide / 4 h / 50 °C
2: triethylamine / N,N-dimethyl-formamide / 6 h / 100 °C
3: iron; ammonium chloride / ethanol; water / 5 h / Reflux
4: ethanol; water / 2 h / 20 °C
View Scheme
2-ethoxy-4-nitro-5-chlorobenzoic acid methyl ester

2-ethoxy-4-nitro-5-chlorobenzoic acid methyl ester

mosapride citrate
112885-42-4

mosapride citrate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triethylamine / N,N-dimethyl-formamide / 6 h / 100 °C
2: iron; ammonium chloride / ethanol; water / 5 h / Reflux
3: ethanol; water / 2 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: N,N-dimethyl-formamide / 6 h / 100 °C
2: iron; ammonium chloride / ethanol; water / 5 h / Reflux
3: ethanol; water / 2 h / 20 °C
View Scheme
mosapride citrate
112885-42-4

mosapride citrate

mosapride
112885-41-3

mosapride

mosapride citrate
112885-42-4

mosapride citrate

citric acid
77-92-9

citric acid

A

C27H31ClFN3O9

C27H31ClFN3O9

B

C27H31ClFN3O10

C27H31ClFN3O10

Conditions
ConditionsYield
at 105℃; for 17h;

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