Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-carboxylate

Cas:113451-59-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(1S,4S)-N-(tert-Butoxycarbonyl)-2,5-diazabicyclo[2.2.1]heptane

Cas:113451-59-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE Synonyms: TERT-BUTYL (1S, 4S)-(-)-2,5-DIAZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE;TERT-BUTYL (1S,4S)-2,5-DIAZABICYCLO(2.2.1)HEPTANE-2-CARBOXYLATE;1,1-DIMETHYLETHYL (1S,4S)-2,5-DIA

113451-59-5 (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:1 Kilogram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE CAS 113451-59-5

Cas:113451-59-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 113451-59-5 with fast shipping

Cas:113451-59-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE CAS:113451-59-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE CAS:113451-59-5

Cas:113451-59-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester, (1S,4S)-

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester, (1S,4S)-

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester, (1S,4S)-

Cas:113451-59-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply (1S,4S)-2-BOC-2,5-diazabicyclo(2.2.1)heptane

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Other

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE Synonyms: TERT-BUTYL (1S, 4S)-(-)-2,5-DIAZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE;TERT-BUTYL (1S,4S)-2,5-DIAZABICYCLO(2.2.1)HEPTANE-2-CARBOXYLATE;(1S,4S)-N-(TERT-BUTOXYCARBONYL)-2,5-DIAZAB

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

Cas:113451-59-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

tert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE cas no. 113451-59-5 98%

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

(1S,4S)-2-BOC-2,5-diazabicyclo(2.2.1)heptane

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

(1S,4S)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate hydrochloride

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

stocks,competitive price,superior product If you nee, pls feel free to contact me. Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:R&D Transportation:sh

(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

Cas:113451-59-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE CAS No.113451-59-5

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-carboxylate cas 113451-59-5Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

SAGECHEM LIMITED

113451-59-5 Application:intermediate

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid, 1,1-dimethylethyl ester, (1S,4S)-

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

low price and high purityAppearance:solid or liquid Storage:in sealed air resistant place Package:As customer require Application:Pharma;Industry;Agricultural Transportation:by sea or by airplane Port:any port in China

(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane, 97% 113451-59-5

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(1S,4S)-tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate hydrochloride

Cas:113451-59-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(2S,4R)-2-(azidomethyl)-1-(tert-butoxycarbonyl)-4-<(methylsulfonyl)oxy>pyrrolidine
113451-54-0

(2S,4R)-2-(azidomethyl)-1-(tert-butoxycarbonyl)-4-<(methylsulfonyl)oxy>pyrrolidine

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol100%
Stage #1: (2S,4R)-2-(azidomethyl)-1-(tert-butoxycarbonyl)-4-<(methylsulfonyl)oxy>pyrrolidine With triphenylphosphine In tetrahydrofuran at 20℃; for 2h; Staudinger Azide Reduction;
Stage #2: With water In tetrahydrofuran for 18h;
71%
(1S,4S)-5-Benzyl-2-tert-butoxycarbonyl-2,5-diazabicyclo<2.2.1>heptane
132666-68-3

(1S,4S)-5-Benzyl-2-tert-butoxycarbonyl-2,5-diazabicyclo<2.2.1>heptane

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With palladium hydroxide 10 wt. % on activated carbon; hydrogen In methanol under 3102.97 Torr;90%
With palladium 10% on activated carbon; hydrogen In methanol at 50℃; under 22502.3 Torr; for 16h;85%
With 10% palladium on carbon; hydrogen76%
With palladium 10% on activated carbon; hydrogen In dichloromethane under 3102.97 Torr;10.4 g
tert-butyl (2S,4S)-4-amino-2-(hydroxymethyl)pyrrolidin-1-carboxylate
922139-40-0

tert-butyl (2S,4S)-4-amino-2-(hydroxymethyl)pyrrolidin-1-carboxylate

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 22 - 25℃; for 12h; Inert atmosphere;80.6%
L-4-hydroxyproline methyl ester hydrochloride
40216-83-9

L-4-hydroxyproline methyl ester hydrochloride

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: triethylamine / dichloromethane / 17 h / 0 °C
2.1: lithium borohydride / tetrahydrofuran / 26 h / 0 - 20 °C
3.1: pyridine / dichloromethane / 18 h / 40 °C
4.1: trimethylsilylazide; tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 70 °C
5.1: triethylamine / dichloromethane / 0.5 h / 0 °C
6.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C
6.2: 18 h
View Scheme
4R-4-hydroxyproline
51-35-4

4R-4-hydroxyproline

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: thionyl chloride; hydrogenchloride / water / 18 h / 20 °C / Reflux
2.1: triethylamine / dichloromethane / 17 h / 0 °C
3.1: lithium borohydride / tetrahydrofuran / 26 h / 0 - 20 °C
4.1: pyridine / dichloromethane / 18 h / 40 °C
5.1: trimethylsilylazide; tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 70 °C
6.1: triethylamine / dichloromethane / 0.5 h / 0 °C
7.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C
7.2: 18 h
View Scheme
Multi-step reaction with 6 steps
1.1: sodium carbonate / water
1.3: 20 h
2.1: toluene / Reflux
3.1: hydrogen bromide
4.1: sodium methylate / methanol / 20 °C
5.1: triethylamine / dichloromethane / 0 - 20 °C
6.1: hydrogen; palladium hydroxide 10 wt. % on activated carbon / methanol / 3102.97 Torr
View Scheme
1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
74844-91-0

1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: lithium borohydride / tetrahydrofuran / 26 h / 0 - 20 °C
2.1: pyridine / dichloromethane / 18 h / 40 °C
3.1: trimethylsilylazide; tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 70 °C
4.1: triethylamine / dichloromethane / 0.5 h / 0 °C
5.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C
5.2: 18 h
View Scheme
Multi-step reaction with 4 steps
1: triethylamine / dichloromethane / 2 h / 5 - 25 °C
2: sodium azide / N,N-dimethyl-formamide / 3 h / 90 °C
3: potassium borohydride; lithium chloride / tetrahydrofuran / 12 h / 25 °C
4: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 22 - 25 °C / Inert atmosphere
View Scheme
Multi-step reaction with 4 steps
1: sodium tetrahydroborate / methanol / 18 h / 20 - 35 °C / Cooling with ice; Large scale
2: triethylamine / dichloromethane / 1 h / 20 - 35 °C / Cooling with liquid nitrogen; Large scale
3: 3 h / 80 °C / Large scale
4: palladium 10% on activated carbon; hydrogen / methanol / 16 h / 50 °C / 22502.3 Torr
View Scheme
tert-butyl (2S,4R)-4-hydroxy-2-hydroxymethyl-pyrrolidine-1-carboxylate
61478-26-0

tert-butyl (2S,4R)-4-hydroxy-2-hydroxymethyl-pyrrolidine-1-carboxylate

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: pyridine / dichloromethane / 18 h / 40 °C
2.1: trimethylsilylazide; tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 70 °C
3.1: triethylamine / dichloromethane / 0.5 h / 0 °C
4.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C
4.2: 18 h
View Scheme
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 1 h / 20 - 35 °C / Cooling with liquid nitrogen; Large scale
2: 3 h / 80 °C / Large scale
3: palladium 10% on activated carbon; hydrogen / methanol / 16 h / 50 °C / 22502.3 Torr
View Scheme
tert-butyl (2S,4R)-4-hydroxy-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-pyrrolidine-1-carboxylate
194089-91-3

tert-butyl (2S,4R)-4-hydroxy-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-pyrrolidine-1-carboxylate

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: trimethylsilylazide; tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 70 °C
2.1: triethylamine / dichloromethane / 0.5 h / 0 °C
3.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C
3.2: 18 h
View Scheme
(2S,4R)-tert-butyl 2-(azidomethyl)-4-hydroxypyrrolidine-1-carboxylate
114676-96-9

(2S,4R)-tert-butyl 2-(azidomethyl)-4-hydroxypyrrolidine-1-carboxylate

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 0.5 h / 0 °C
2.1: triphenylphosphine / tetrahydrofuran / 2 h / 20 °C
2.2: 18 h
View Scheme
N-tert-butoxycarbonyl-cis-4-azido-L-proline methyl ester
84520-68-3

N-tert-butoxycarbonyl-cis-4-azido-L-proline methyl ester

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium borohydride; lithium chloride / tetrahydrofuran / 12 h / 25 °C
2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 22 - 25 °C / Inert atmosphere
View Scheme
(2S,4R)-4-(methylsulfonyloxy)pyrrolidine-1,2-dicarboxylic acid 1-tert-butylester-2-methylester
84520-67-2

(2S,4R)-4-(methylsulfonyloxy)pyrrolidine-1,2-dicarboxylic acid 1-tert-butylester-2-methylester

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium azide / N,N-dimethyl-formamide / 3 h / 90 °C
2: potassium borohydride; lithium chloride / tetrahydrofuran / 12 h / 25 °C
3: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 12 h / 22 - 25 °C / Inert atmosphere
View Scheme
(2S,4R)-1-(4-tolylsulfonyl)-4-<(4-tolylsulfonyl)oxy>-2-<<(4-tolylsulfonyl)oxy>methyl>pyrrolidine
5234-75-3

(2S,4R)-1-(4-tolylsulfonyl)-4-<(4-tolylsulfonyl)oxy>-2-<<(4-tolylsulfonyl)oxy>methyl>pyrrolidine

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: toluene / Reflux
2: hydrogen bromide
3: sodium methylate / methanol / 20 °C
4: triethylamine / dichloromethane / 0 - 20 °C
5: hydrogen; palladium hydroxide 10 wt. % on activated carbon / methanol / 3102.97 Torr
View Scheme
(1S,4S)-5-Benzyl-2-tosyl-2,5-diazabicyclo<2.2.1>heptane
5234-72-0

(1S,4S)-5-Benzyl-2-tosyl-2,5-diazabicyclo<2.2.1>heptane

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogen bromide
2: sodium methylate / methanol / 20 °C
3: triethylamine / dichloromethane / 0 - 20 °C
4: hydrogen; palladium hydroxide 10 wt. % on activated carbon / methanol / 3102.97 Torr
View Scheme
(1S,4S)-2-Benzyl-2,5-diazabicyclo<2.2.1>heptane dihydrobromide
100944-15-8, 134003-82-0, 116258-17-4

(1S,4S)-2-Benzyl-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium methylate / methanol / 20 °C
2: triethylamine / dichloromethane / 0 - 20 °C
3: hydrogen; palladium hydroxide 10 wt. % on activated carbon / methanol / 3102.97 Torr
View Scheme
Multi-step reaction with 3 steps
1: sodium methylate / methanol / 20 °C
2: triethylamine / dichloromethane / 0 - 20 °C
3: palladium 10% on activated carbon; hydrogen / dichloromethane / 3102.97 Torr
View Scheme
(1S,4S)-N-Benzyl-2,5-diazabicyclo-[2.2.1]heptane
127641-07-0

(1S,4S)-N-Benzyl-2,5-diazabicyclo-[2.2.1]heptane

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 0 - 20 °C
2: hydrogen; palladium hydroxide 10 wt. % on activated carbon / methanol / 3102.97 Torr
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 0 - 20 °C
2: palladium 10% on activated carbon; hydrogen / dichloromethane / 3102.97 Torr
View Scheme
2-(2-ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine-8-carbaldehyde
1257295-06-9

2-(2-ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine-8-carbaldehyde

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

C30H39N9O3
1257382-14-1

C30H39N9O3

Conditions
ConditionsYield
Stage #1: 2-(2-ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purine-8-carbaldehyde; (1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester In 1,2-dichloro-ethane at 20℃; for 3h; Molecular sieve;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃; for 17h; Molecular sieve;
100%
(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-2,5-Diazabicyclo<2.2.1>heptane dihydrochloride
5260-20-8, 89487-38-7

(1S,4S)-2,5-Diazabicyclo<2.2.1>heptane dihydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane; methanol at 20℃; for 0.5h;100%
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-2-methanesulfonyl-2,5-diazabicyclo[2.2.1]heptane-5-carboxylic acid tert-butyl ester

(1S,4S)-2-methanesulfonyl-2,5-diazabicyclo[2.2.1]heptane-5-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0 - 20℃; for 20h;100%
With triethylamine In tetrahydrofuran at 0 - 30℃; for 12h; Inert atmosphere;100%
isobutyryl chloride
79-30-1

isobutyryl chloride

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4S)-5-isobutyryl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl (1S,4S)-5-isobutyryl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; Inert atmosphere;100%
5-bromopyrimidine
4595-59-9

5-bromopyrimidine

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4S)-5-(5-pyrimidinyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl (1S,4S)-5-(5-pyrimidinyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
99%
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 80 - 85℃; for 5h;91%
With tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate In toluene at 80 - 85℃; for 5h;91%
3-Bromopyridine
626-55-1

3-Bromopyridine

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-tert-butyl 5-(pyridin-3-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
286946-36-9

(1S,4S)-tert-butyl 5-(pyridin-3-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
99%
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 85℃; for 64h; Inert atmosphere;99%
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 80 - 85℃; for 5h;
2,5 dichloropyridine
16110-09-1

2,5 dichloropyridine

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4S)-5-(5-chloro-2-pyridinyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl (1S,4S)-5-(5-chloro-2-pyridinyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
99%
ethyl 6-chloro-5-cyano-2-methylnicotinate
64119-42-2

ethyl 6-chloro-5-cyano-2-methylnicotinate

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-tert-butyl 5-(3-cyano-5-(ethoxycarbonyl)-6-methylpyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
898229-94-2

(1S,4S)-tert-butyl 5-(3-cyano-5-(ethoxycarbonyl)-6-methylpyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 1h;99%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 1h;99%
4-tert-butylbenzenesulfonyl chloride
15084-51-2

4-tert-butylbenzenesulfonyl chloride

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

C20H30N2O4S
1116571-82-4

C20H30N2O4S

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 48h;99%
With N-ethyl-N,N-diisopropylamine In dichloromethane
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 16h; Inert atmosphere;
1-iodo-2-diphenylmethoxy-ethane
153947-34-3

1-iodo-2-diphenylmethoxy-ethane

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-2-[2-(diphenylmethoxy)ethyl]-5-t-Boc-2,5-diazabicyclo[2.2.1]heptane
321365-86-0

(1S,4S)-2-[2-(diphenylmethoxy)ethyl]-5-t-Boc-2,5-diazabicyclo[2.2.1]heptane

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran Heating;98%
cis-4-(1-(6-iodo-2-methylpyrimidin-4-yl)-5-methyl-1H-indazol-6-yl)-1-methylcyclohexanol

cis-4-(1-(6-iodo-2-methylpyrimidin-4-yl)-5-methyl-1H-indazol-6-yl)-1-methylcyclohexanol

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

cis-(1S,4S)-tert-butyl 5-(6-(6-(4-hydroxy-4-methylcyclohexyl)-5-methyl-1H-indazol-1-yl)-2-methylpyrimidin-4-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

cis-(1S,4S)-tert-butyl 5-(6-(6-(4-hydroxy-4-methylcyclohexyl)-5-methyl-1H-indazol-1-yl)-2-methylpyrimidin-4-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 50℃;98%
bromobenzene
108-86-1

bromobenzene

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

C16H22N2O2

C16H22N2O2

Conditions
ConditionsYield
With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 80 - 85℃; for 5h;97%
1-(3-methoxy-4 nitrophenyl)piperidin-4-one
761440-64-6

1-(3-methoxy-4 nitrophenyl)piperidin-4-one

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

1,1-dimethylethyl (1S,4S)-5-{1-[3-(methyloxy)-4-nitrophenyl]-4-piperidinyl}-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1089280-04-5

1,1-dimethylethyl (1S,4S)-5-{1-[3-(methyloxy)-4-nitrophenyl]-4-piperidinyl}-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
Stage #1: 1-(3-methoxy-4 nitrophenyl)piperidin-4-one; (1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester With sodium tris(acetoxy)borohydride; acetic acid; triethylamine In dichloromethane for 1h;
Stage #2: With sodium hydrogencarbonate In dichloromethane; water
96%
(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Acetoxyacetyl chloride
13831-31-7

Acetoxyacetyl chloride

5-(2-acetoxy-acetyl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
1146691-54-4

5-(2-acetoxy-acetyl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: (1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester With triethylamine In dichloromethane at 5℃; for 0.833333h;
Stage #2: Acetoxyacetyl chloride In dichloromethane for 16h;
96%
1-(2,4,6-trifluorophenyl)ethan-1-one
51788-77-3

1-(2,4,6-trifluorophenyl)ethan-1-one

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4S)-5-(2-acetyl-3,5-difluorophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1196958-94-7

tert-butyl (1S,4S)-5-(2-acetyl-3,5-difluorophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In 1,4-dioxane at 100℃; for 24h; Inert atmosphere; regioselective reaction;96%
(1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid
851916-39-7

(1S,4S)-4-(2,5-dimethyl-1H-pyrrol-1-yl)-1-isopropylcyclopent-2-ene-1-carboxylic acid

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

C25H37N3O3
1294006-20-4

C25H37N3O3

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine In N,N-dimethyl-formamide at 0℃;95%
4-chloromethylbenzaldehyde
73291-09-5

4-chloromethylbenzaldehyde

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4S)-5-(4-formylbenzyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl (1S,4S)-5-(4-formylbenzyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 50℃;93.1%
(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

(1S,4S)-5-(2,2,2-trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
878805-66-4

(1S,4S)-5-(2,2,2-trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0℃; for 5h; Inert atmosphere;93%
With triethylamine In tetrahydrofuran at 20℃; for 1h;
2-[2-(N-benzyloxycarbonyl-2-aminoethoxy)ethoxy]-1-bromoethane

2-[2-(N-benzyloxycarbonyl-2-aminoethoxy)ethoxy]-1-bromoethane

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-tert-butyl 5-(3-oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-yl)- 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

(1S,4S)-tert-butyl 5-(3-oxo-1-phenyl-2,7,10-trioxa-4-azadodecan-12-yl)- 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃; for 24h;93%
With potassium carbonate In acetonitrile at 80℃; for 24h;93%
N-(Benzyloxycarbonyl)glycine
1138-80-3

N-(Benzyloxycarbonyl)glycine

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

1,1-dimethylethyl(1S,4S)-5-(N-{[benzyloxy]carbonyl}glycyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
774610-01-4

1,1-dimethylethyl(1S,4S)-5-(N-{[benzyloxy]carbonyl}glycyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With 3-methyl-N-(3-methylbutyl)-1-butanamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;92%
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane
With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane at 20℃; for 24h; Product distribution / selectivity;
2-[4-(2-bromoethoxy)phenoxy]benzothiazole
841200-43-9

2-[4-(2-bromoethoxy)phenoxy]benzothiazole

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(S,S)-5-(2-[4-(benzothiazol-2-yloxy)-phenoxy]-ethyl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
1146691-49-7

(S,S)-5-(2-[4-(benzothiazol-2-yloxy)-phenoxy]-ethyl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 20 - 60℃; for 69h;92%
(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

calcium 1-(5-(tert-butoxycarbonyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)diazen-1-ium-1,2-diolate

calcium 1-(5-(tert-butoxycarbonyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)diazen-1-ium-1,2-diolate

Conditions
ConditionsYield
With nitrogen(II) oxide; calcium hydroxide In water at 20℃; under 12929 Torr; for 120h; Green chemistry;92%
(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

2-[bis(4-fluorophenyl)methoxy]ethyl iodide
321365-84-8

2-[bis(4-fluorophenyl)methoxy]ethyl iodide

3-[2-[bis(4-fluorophenyl)methoxy]ethyl]-8-(1S,4S)-N-t-Boc-2,5-diazabicyclo[2.2.1]heptane
321365-88-2

3-[2-[bis(4-fluorophenyl)methoxy]ethyl]-8-(1S,4S)-N-t-Boc-2,5-diazabicyclo[2.2.1]heptane

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran Heating;91%
6-ethoxy-4-(6-fluoropyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

6-ethoxy-4-(6-fluoropyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4 S)-5-(5-(3-cyano-6-ethoxypyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl (1S,4 S)-5-(5-(3-cyano-6-ethoxypyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 90℃;90%
6-methoxy-3-pyridinecarboxaldehyde
65873-72-5

6-methoxy-3-pyridinecarboxaldehyde

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

tert-butyl (1S,4S)-5-(6-methoxypyridin-3-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl (1S,4S)-5-(6-methoxypyridin-3-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20℃;90%
2-fluoro-5-nitrobenzaldehye
27996-87-8

2-fluoro-5-nitrobenzaldehye

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-tert-butyl 5-(2-formyl-4-nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

(1S,4S)-tert-butyl 5-(2-formyl-4-nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50℃; Inert atmosphere;89%
Fmoc-Leu-OH
35661-60-0

Fmoc-Leu-OH

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

1,1-dimethylethyl (1S,4S)-5-(N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-L-leucyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1186643-72-0

1,1-dimethylethyl (1S,4S)-5-(N-{[(9H-fluoren-9-ylmethyl)oxy]carbonyl}-L-leucyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;88.3%
5-(3-(4-(2-bromoethoxy)-3-ethylphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-3-(trifluoromethyl)picolinonitrile

5-(3-(4-(2-bromoethoxy)-3-ethylphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-3-(trifluoromethyl)picolinonitrile

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
113451-59-5

(1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

(1S,4S)-tert-butyl 5-(2-(4-(3-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-ethylphenoxy)ethyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

(1S,4S)-tert-butyl 5-(2-(4-(3-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-ethylphenoxy)ethyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃; for 12h;87.7%

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View