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Cas:113994-41-5
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o
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Min.Order:1 Kilogram
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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Min.Order:1 Kilogram
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Min.Order:1 Metric Ton
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inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
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inquiry113994-41-5 Amlodipine Impurity D Application:113994-41-5 Amlodipine Impurity D
2-[(2-AMINOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTERAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by
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inquiry113994-41-5 Amlodipine Impurity DAppearance:white powder Storage:sealed preservation at room temperature Package:Aluminium foil bag with carton outside Application:impurity Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small am
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inquiryGood Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
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inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
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Min.Order:0
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Min.Order:10 Milligram
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Type:Lab/Research institutions
inquiry2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
With hydrazine hydrate In ethanol at 20℃; for 20h; | 98% |
With hydrazine In methanol; toluene at 20℃; for 4h; | 61% |
(R)-2-[(2-aminoethoxy)methyl]4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
With calcium hypochlorite In water; ethyl acetate at 20 - 30℃; Reagent/catalyst; Temperature; Solvent; | 93.4% |
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
Stage #1: 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine With hydrogenchloride In water Stage #2: With nickel In water at 20℃; for 6h; | 73.2% |
With potassium permanganate In 1,4-dioxane; water for 16h; Ambient temperature; | |
With potassium superoxide In dimethyl sulfoxide at 37℃; for 5h; Kinetics; |
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
With Britton-Robinson buffer In water; N,N-dimethyl-formamide at 37℃; pH=7.4; Kinetics; |
4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-[2-phthalimidoethoxymethyl]-1,4-dihydropyridine
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 97 percent / Pb(OAc)4 / CH2Cl2; acetic acid / 19 h / 20 °C 2: 98 percent / hydrazine monohydrate / aq. ethanol / 20 h / 20 °C View Scheme |
amlodipine
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
With human P450 enzyme CYP3A4; NADPH In aq. phosphate buffer for 0.216667h; pH=7.4; Enzymatic reaction; |
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
C
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
With sodium hypochlorite; octabromotetrakis(2,6-dichlorophenyl)porphyrin Fe(III)Cl; water In acetonitrile at 80℃; for 0.166667h; Microwave irradiation; |
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
I
4-(2-Chloro-phenyl)-2,6-dimethyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
J
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
In water at 10℃; Irradiation; |
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
L-Pyroglutamic acid
Conditions | Yield |
---|---|
In ethyl acetate at 25℃; for 1h; | 95.3% |
In ethyl acetate at 25℃; for 1h; | 95.3% |
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Pyroglutamic acid
Conditions | Yield |
---|---|
95.2% |
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
D-pyrrolidone-5-carboxylic acid
Conditions | Yield |
---|---|
95.1% |
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid at 15 - 25℃; for 2h; Reagent/catalyst; Temperature; | 93.1% |
(2E)-but-2-enedioic acid
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
In ethanol Heating; | 8.4 g |
toluene-4-sulfonic acid
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
In methanol at 23℃; for 3h; |
2-(2-Amino-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 23℃; for 3h; |
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