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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

USDMF EDMF is under preparing! Hangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the r

MLN4924 hydrochloride

Cas:1160295-21-5

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl ester hydrochloride CAS:1160295-21-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological co

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

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Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Pevonedistat HCl 1160295-21-5

Cas:1160295-21-5

Min.Order:100 Milligram

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Type:Lab/Research institutions

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NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

Pevonedistathydrochloride

Cas:1160295-21-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:Active Pharmaceutical I

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

1160295-21-5

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

MLN4924 hydrochloride

Cas:1160295-21-5

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Sun-shine Bio-technology Corporation Limited

Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization. Company has strong ability of research and development

MLN4924 HClwith factory price

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of plant

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai AngewChem Co., Ltd.

Shanghai AngewChemCo., Ltd. is an innovative enterprise on fine chemicals and pharmaceuticals. Based on Shanghai R&D center and Hunan chemical manufacturing plant, we offer chemical research, process development, and large-scale production. Complete

Shanghai HengXun Pharmaceutical Tech. Co., Ltd.

1160295-21-5 Appearance:white powder Storage:Keep in cool and dry place, away from light Package:25kg/plastic drum,200Kg/iron drum Port:Shanghai, Shenzhen, Guangzhou, Hongkong,

MLN-4924 hydrochloride

Cas:1160295-21-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Raymon Biotech Co., Ltd.

[(1s,2s,4r)-4-[4-[[(1s)-2,3-dihydro-1h-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl Sulfamate Hydrochloride Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical resear

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

1160295-21-5

Cas:1160295-21-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

(1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-(hydroxymethyl)-cyclopentanol
905580-90-7

(1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-(hydroxymethyl)-cyclopentanol

(1,4-diazabicyclo[2.2.2]octan-1-ium-1-ylsulfonyl)(tert-butoxycarbonyl)amide
1375958-75-0

(1,4-diazabicyclo[2.2.2]octan-1-ium-1-ylsulfonyl)(tert-butoxycarbonyl)amide

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride
1160295-21-5

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride

Conditions
ConditionsYield
Stage #1: (1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-(hydroxymethyl)-cyclopentanol; (1,4-diazabicyclo[2.2.2]octan-1-ium-1-ylsulfonyl)(tert-butoxycarbonyl)amide In acetonitrile at 55℃; for 8h;
Stage #2: With hydrogenchloride In water; acetonitrile at 20℃; for 2h;
42%
((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride
1160295-21-5

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 50℃; Product distribution / selectivity; Reflux;
C20H20O5

C20H20O5

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride
1160295-21-5

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: di-tert-butyl-diazodicarboxylate; phosphorous acid trimethyl ester / toluene / 3 h / 12 °C
2.1: N-ethyl-N,N-diisopropylamine / butan-1-ol / 24 h / 25 °C
3.1: hydrogenchloride; water / tetrahydrofuran / 4.5 h / 40 °C
4.1: acetonitrile / 8 h / 55 °C
4.2: 2 h / 20 °C
View Scheme
4-chloro-1H-pyrrolo[2,3-d]pyrimidine
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride
1160295-21-5

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: di-tert-butyl-diazodicarboxylate; phosphorous acid trimethyl ester / toluene / 3 h / 12 °C
2.1: N-ethyl-N,N-diisopropylamine / butan-1-ol / 24 h / 25 °C
3.1: hydrogenchloride; water / tetrahydrofuran / 4.5 h / 40 °C
4.1: acetonitrile / 8 h / 55 °C
4.2: 2 h / 20 °C
View Scheme
C26H22ClN3O4

C26H22ClN3O4

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride
1160295-21-5

((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)-methyl sulfamate hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / butan-1-ol / 24 h / 25 °C
2.1: hydrogenchloride; water / tetrahydrofuran / 4.5 h / 40 °C
3.1: acetonitrile / 8 h / 55 °C
3.2: 2 h / 20 °C
View Scheme

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