As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis
Cas:127168-88-1
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryCAS: 127168-88-1 Chemical formula: C9H11NO Molecular weight: 149.19 InchI: InchI=1/C9H11NO/c1-11-9-3-2-7-5-10-6-8 (7) 4-9/h2-4,10H, 5-6H2,1H3 Density: 1.076 Boiling point: 254 ℃ Flash point: 95 ℃ Steam pressure: 0.018mm Hg at 25 ° C Refractive in
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inquiry1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd
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inquiry5-METHOXY-2,3-DIHYDRO-1H-ISOINDOLE CAS:127168-88-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:127168-88-1
Min.Order:10 Gram
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:127168-88-1
Min.Order:1 Gram
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inquiryProduct Name: 5-METHOXY-2,3-DIHYDRO-1H-ISOINDOLE Synonyms: 5-METHOXY-2,3-DIHYDRO-1H-ISOINDOLE;2,3-Dihydro-5-methoxy-1H-isoindole;5-METHOXYISOINDOLINE;5-METHOXY-2,3-DIHYDRO-1H-ISOINDOL;m90100;5-METHOXYISOINDOLINE HCL;1H-Isoindole,2,3-dihydro-5-M
Cas:127168-88-1
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryHunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Cas:127168-88-1
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Type:Trading Company
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:127168-88-1
Min.Order:1 Kilogram
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inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:127168-88-1
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inquiryAppearance:Solid powder Storage:Sealed,light and oxygen resistant Package:Foil bag or drum Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals Transportation:by sea or air Port:Beijing or Guangzhou Port
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
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inquiryhigh qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
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inquiryShanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
Cas:127168-88-1
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inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
Cas:127168-88-1
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inquirybest seller Application:API
Cas:127168-88-1
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Type:Manufacturers
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:127168-88-1
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inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
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inquirybest seller Application:API
Cas:127168-88-1
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inquiry1H-Isoindole,2,3-dihydro-5-methoxy- cas 127168-88-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:127168-88-1
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inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:127168-88-1
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inquiry127168-88-1 Application:intermediate
Cas:127168-88-1
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inquiryR & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou
Cas:127168-88-1
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inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
4-methoxyphthalimide
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
Stage #1: 4-methoxyphthalimide With borane-THF In tetrahydrofuran at 0℃; for 16h; Heating / reflux; Stage #2: With hydrogenchloride In tetrahydrofuran; methanol; water for 3h; Heating / reflux; | 47% |
Stage #1: 4-methoxyphthalimide With borane-THF In tetrahydrofuran at 0℃; for 16h; Heating / reflux; Stage #2: With hydrogenchloride In tetrahydrofuran; methanol at 0℃; for 3h; Heating / reflux; | 47% |
With borane In tetrahydrofuran at 0℃; for 16h; Heating / reflux; | 47% |
N-benzylisoindolin-5-yl methyl ether
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With Pd(OH)2/C; ammonium formate In methanol Reflux; | |
Stage #1: N-benzylisoindolin-5-yl methyl ether With hydrogen; acetic acid; palladium on carbon In methanol under 2327.23 Torr; for 23h; Stage #2: With sodium hydroxide; water In methanol |
5-methoxy-2-[(4-methylphenyl)sulfonyl]isoindoline
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With hydrogen bromide; phenol In propan-1-ol; water at 100℃; for 2h; |
3,4-dimethylanisole
5-methoxy-2,3-dihydro-1H-isoindole
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With hydrogen bromide In water at 100℃; | 95% |
With hydrogen bromide In water for 16h; Heating / reflux; | 93% |
With hydrogen bromide In water for 16h; Heating / reflux; | 93% |
5-methoxy-2,3-dihydro-1H-isoindole
5-hydroxyisoindoline
Conditions | Yield |
---|---|
With hydrogen bromide at 100℃; for 2h; | 80% |
4-bromophenyl chloroformate
5-methoxy-2,3-dihydro-1H-isoindole
4-bromophenyl 5-methoxyisoindoline-2-carboxylate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 1h; | 63% |
2-(4-(4-oxo-3,4-dihydrophthalazin-1-yl)phenyl)acetic acid
5-methoxy-2,3-dihydro-1H-isoindole
4-(4-(2-(5-methoxyisoindolin-2-yl)-2-oxoethyl)phenyl)phthalazin-1(2H)-one
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h; | 59% |
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With triethylamine In 1-methyl-pyrrolidin-2-one at 150℃; for 1h; | 48.9% |
2,6-Dichloropyrimidine
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With sodium carbonate In ethanol at 90℃; for 12h; | 47.8% |
(4-bromophenyl)(2-chloropyrimidin-4-yl)amine
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 17h; | 42.9% |
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 17h; | 42.9% |
2-chloropyrimidin-4-amine
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 16h; | 35.4% |
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 16h; | 35.4% |
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 90℃; for 72h; | 30% |
With potassium carbonate In acetonitrile at 90℃; for 72h; | 30% |
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With triethylamine In 1-methyl-pyrrolidin-2-one at 150℃; for 1h; | 29.6% |
N-(2,5-dichloropyrimidin-4-yl)-1H-indazol-5-amine
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 12h; | 29.1% |
N-(2-chloro-5-methylpyrimidin-4-yl)-1H-indazol-5-amine
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 110℃; for 12h; | 27% |
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 110℃; for 12h; | 21.4% |
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 20h; | 17.2% |
2-chloro-5-fluoro-N-(indazoline-5-yl)-4-pyrimidineamine
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In acetonitrile at 90℃; for 12h; | 12.1% |
5-methoxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
With triethylamine In 1,4-dioxane at 150℃; for 2h; Microwave irradiation; Sealed tube; | 7.23% |
trans-2-(1-(4-(N-tert-butoxycarbonyl)amino)cyclohexyl)acetaldehyde
5-methoxy-2,3-dihydro-1H-isoindole
{4-[2-(5-methoxy-1,3-dihydro-isoindol-2-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
With NaBH(OAc)2 In 1,2-dichloro-ethane at 20℃; for 16h; |
5-methoxy-2,3-dihydro-1H-isoindole
5-cyano-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 6 h / -20 - 20 °C 4: 90 percent / Pd(PPh3)4 / dimethylformamide / 4 h / 100 °C 5: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
5-methanesulfonyloxy-2,3-dihydro-1H-isoindole
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 16 h / 20 °C 4: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
tert-butyl 5-hydroxyisoindoline-2-carboxylate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
tert-butyl 5-cyanoisoindoline-2-carboxylate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 6 h / -20 - 20 °C 4: 90 percent / Pd(PPh3)4 / dimethylformamide / 4 h / 100 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
5-methanesulfonyloxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 16 h / 20 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
4-[2-(5-methoxy-1,3-dihydro-isoindol-2-yl)-ethyl]-cyclohexylamine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NaBH(OAc)2 / 1,2-dichloro-ethane / 16 h / 20 °C 2: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
5-trifluoromethanesulfonyloxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 6 h / -20 - 20 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
2-[2-(4-amino-cyclohexyl)-ethyl]-2,3-dihydro-1H-isoindole-5-carbonitrile
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 6 h / -20 - 20 °C 4: 90 percent / Pd(PPh3)4 / dimethylformamide / 4 h / 100 °C 5: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C 6: NaBH(OAc)2 / 1,2-dichloro-ethane / 16 h / 20 °C 7: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
methanesulfonic acid 2-[2-(4-amino-cyclohexyl)-ethyl]-2,3-dihydro-1H-isoindol-5-yl ester
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 16 h / 20 °C 4: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C 5: NaBH(OAc)2 / 1,2-dichloro-ethane / 16 h / 20 °C 6: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
{4-[2-(5-cyano-1,3-dihydro-isoindol-2-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 6 h / -20 - 20 °C 4: 90 percent / Pd(PPh3)4 / dimethylformamide / 4 h / 100 °C 5: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C 6: NaBH(OAc)2 / 1,2-dichloro-ethane / 16 h / 20 °C View Scheme |
5-methoxy-2,3-dihydro-1H-isoindole
methanesulfonic acid 2-[2-(4-tert-butoxycarbonylamino-cyclohexyl)-ethyl]-2,3-dihydro-1H-isoindol-5-yl ester
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 80 percent / aq. HBr / 2 h / 100 °C 2: 40 percent / Et3N / CH2Cl2 / 16 h / 20 °C 3: 70 percent / Et3N / CH2Cl2 / 16 h / 20 °C 4: 90 percent / TFA / CH2Cl2 / 0.5 h / 40 °C 5: NaBH(OAc)2 / 1,2-dichloro-ethane / 16 h / 20 °C View Scheme |
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