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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-(Trifluoromethyl)Nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 13600-43-6 4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

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Henan Allgreen Chemical Co.,Ltd

4-(Trifluoromethyl)nicotinonitrile Basic information Product Name: 4-(Trifluoromethyl)nicotinonitrile Synonyms: BUTTPARK 43\57-45;3-CYANO-4-(TRIFLUOROMETHYL)PYRIDIN

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Cyano-4-(trifluoromethyl)-pyridine

Cas:13600-43-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 13600-43-6 with best quality

Cas:13600-43-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Pyridinecarbonitrile,4-(trifluoromethyl)- 13600-43-6

Cas:13600-43-6

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present,

4-(Trifluoromethyl)nicotinonitrile 13600-43-6

Cas:13600-43-6

Min.Order:1 Kilogram

FOB Price: $675.0 / 689.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3-Pyridinecarbonitrile,4-(trifluoromethyl)-

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

3-Cyano-4-(trifluoromethyl)pyridine CAS NO.13600-43-6

Cas:13600-43-6

Min.Order:10 Gram

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-(Trifluoromethyl)Nicotinonitrile

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:0 Metric Ton

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Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Cyano-4-(trifluoromethyl)pyridine

Cas:13600-43-6

Min.Order:0

Negotiable

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

4-(Trifluoromethyl)nicotinonitrile 13600-43-6

Cas:13600-43-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

4-(Trifluoromethyl)nicotinonitrile Basic information Product Name: 4-(Trifluoromethyl)nicotinonitrile Synonyms: BUTTPARK 43\57-45;3-Cyano-4-(trifluoromethyl)pyridine95+%;3-CYANO-4-(TRIFLUOROMETHYL)PYRIDINE;4-TRIFLUOROMETHYL-3-PYRIDINENITRILE;4-

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Trading Company

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

3-Cyano-4-(trifluoromethyl)pyridine CAS NO.13600-43-6 CAS NO.13600-43-6

Cas:13600-43-6

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3-Cyano-4-(trifluoromethyl)pyridine

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Manufacturers

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Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-(trifluoromethyl)pyridine-3-carbonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

Negotiable

Type:Other

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:NA Storage:It is an important raw material and medical intermediate of synthetic drugs. Package: 1kg/drum or 25kg/drum or as per your request. Application:It is an important raw mate

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-(Trifluoromethyl)nicotinonitrile cas no. 13600-43-6 98%

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3-Cyano-4-(trifluoromethyl)pyridine

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

3-Cyano 4-Trifluoromethylpyridine

Cas:13600-43-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

4-(Trifluoromethyl)Nicotinonitrile

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Manufacturers

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

4-(Trifluoromethyl)nicotinonitrile

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

4-(Trifluoromethyl)nicotinonitrile, 97%

Cas:13600-43-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

2,6-dichloro-4-(trifluoromethyl)pyridine-3-carbonitrile
13600-42-5

2,6-dichloro-4-(trifluoromethyl)pyridine-3-carbonitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
With pyridine; hydrogen In ethanol at 30℃; under 760.051 Torr; for 4h; Reagent/catalyst; Temperature; Solvent; Green chemistry;98.5%
With palladium on activated carbon; hydrogen; triethylamine In tetrahydrofuran for 4h; Time;95.22%
4-ethoxy-1,1,1-trifluoro-3-butene-2-one
59938-06-6, 17129-06-5

4-ethoxy-1,1,1-trifluoro-3-butene-2-one

(E/Z)-3-aminoprop-2-enenitrile
19866-98-9

(E/Z)-3-aminoprop-2-enenitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
Stage #1: 4-ethoxy-1,1,1-trifluoro-3-butene-2-one; (E/Z)-3-aminoprop-2-enenitrile In ethanol for 3h; Reflux; Sealed tube;
Stage #2: With sodium ethanolate In ethanol for 5h; Reagent/catalyst; Solvent; Reflux; Sealed tube;
96.7%
(Z)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile
533932-97-7

(Z)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile

(E)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile
533932-96-6

(E)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
With sodium methylate In methanol at 20℃; for 2h; Heating / reflux;56.5%
With potassium carbonate In methanol for 2h; Heating / reflux;32.7%
(Z)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile
533932-97-7

(Z)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
With sodium methylate In methanol at 20℃; for 2h; Heating / reflux;47.2%
3-cyanopyridin-1-ium-1-yl tris(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)borate

3-cyanopyridin-1-ium-1-yl tris(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)borate

(trifluoromethyl)trimethylsilane
81290-20-2

(trifluoromethyl)trimethylsilane

A

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

B

6-(trifluoromethyl)nicotinonitrile
216431-85-5

6-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
Stage #1: 3-cyanopyridin-1-ium-1-yl tris(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)borate; (trifluoromethyl)trimethylsilane With tetrabutylammonium triphenyldifluorosilicate In ethyl acetate at -40℃; for 11h; Molecular sieve; Inert atmosphere;
Stage #2: With bis-[(trifluoroacetoxy)iodo]benzene In ethyl acetate at 25℃; for 10h; Inert atmosphere; regioselective reaction;
A 45%
B 18%
(E)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile
533932-96-6

(E)-3-[(4,4,4-trifluoro-3-oxo-1-butenyl)amino]-2-propenenitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
With sodium methylate In methanol at 20℃; for 2h; Heating / reflux;41.5%
3-(4,4,4-trifluoro-3-oxo-1-butenyl)-2-propenenitrile

3-(4,4,4-trifluoro-3-oxo-1-butenyl)-2-propenenitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
With hydrogenchloride; Li2CO3 In methanol
With Li2CO3 In hydrogenchloride; methanol
(1,10-phenanthroline)(trifluoromethyl)copper (I)

(1,10-phenanthroline)(trifluoromethyl)copper (I)

4-bromopyridine-3-carbonitrile
154237-70-4

4-bromopyridine-3-carbonitrile

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 8h; Sealed tube; Inert atmosphere;92 %Spectr.
pyridine-3-carbonitrile
100-54-9

pyridine-3-carbonitrile

A

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

B

6-(trifluoromethyl)nicotinonitrile
216431-85-5

6-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: n-butyllithium / diethyl ether; hexane / 1 h / -78 °C / Inert atmosphere
1.2: -50 - 25 °C / Inert atmosphere
1.3: 12 h / 25 °C / Inert atmosphere
2.1: tetrabutylammonium triphenyldifluorosilicate / ethyl acetate / 11 h / -40 °C / Molecular sieve; Inert atmosphere
2.2: 10 h / 25 °C / Inert atmosphere
View Scheme
2,6-dihydroxy-3-cyano-4-trifluoromethylpyridine N-methylmorpholine

2,6-dihydroxy-3-cyano-4-trifluoromethylpyridine N-methylmorpholine

4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: trichlorophosphate / 18 h / 130 °C / Inert atmosphere
2: triethylamine; hydrogen; palladium on activated carbon / tetrahydrofuran / 4 h
View Scheme
4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

4-(trifluoromethyl)nicotinic acid
158063-66-2

4-(trifluoromethyl)nicotinic acid

Conditions
ConditionsYield
With water; sodium hydroxide at 100℃; Temperature;98.3%
With sodium hydroxide In ethanol at 80℃; for 10h; Temperature; Inert atmosphere;90.1%
Stage #1: 4-(trifluoromethyl)nicotinonitrile With potassium hydroxide; water In water; ethylene glycol at 200℃; for 4h;
Stage #2: With hydrogenchloride In water; ethylene glycol at 20℃;
84%
With sulfuric acid In water at 110℃; for 12h;
4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

{[4-(trifluoromethyl)-3-pyridinyl]methyl}amine
771580-70-2

{[4-(trifluoromethyl)-3-pyridinyl]methyl}amine

Conditions
ConditionsYield
With ammonia; hydrogen; nickel In ethanol under 25858.1 Torr; for 1h;98%
4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

3-cyano-4-(trifluoromethyl)pyridine 1-oxide
287922-66-1

3-cyano-4-(trifluoromethyl)pyridine 1-oxide

Conditions
ConditionsYield
With dihydrogen peroxide; trifluoroacetic anhydride In dichloromethane; water at 0 - 40℃;96%
With urea hydrogen peroxide adduct; trifluoroacetic anhydride In dichloromethane at 0 - 20℃; for 3h;87%
With urea hydrogen peroxide adduct; trifluoroacetic anhydride In dichloromethane at 0 - 20℃; Inert atmosphere;42%
With dihydrogen peroxide; trifluoroacetic acid In dichloromethane; water at 0 - 40℃; for 16h; Inert atmosphere;
4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

4-(trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carbonitrile

4-(trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carbonitrile

Conditions
ConditionsYield
With C46H49CoN3P4(2+)*2BF4(1-); hydrogen; potassium hydroxide In isopropyl alcohol; acetonitrile at 100℃; under 22801.5 Torr; for 48h; Autoclave; Glovebox; chemoselective reaction;89%
4-(trifluoromethyl)nicotinonitrile
13600-43-6

4-(trifluoromethyl)nicotinonitrile

trifluoroacetic acid
76-05-1

trifluoroacetic acid

{[4-(trifluoromethyl)-3-pyridinyl]methyl}amine bistrifluoroacetate

{[4-(trifluoromethyl)-3-pyridinyl]methyl}amine bistrifluoroacetate

Conditions
ConditionsYield
Stage #1: 4-(trifluoromethyl)nicotinonitrile With ammonia; hydrogen; Raney-Ni In methanol for 16h;
Stage #2: trifluoroacetic acid
47%

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