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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Thiazolecarboxylic acid

Cas:14190-59-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 14190-59-1 with fast shipping

Cas:14190-59-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

THIAZOLE-2-CARBOXYLIC ACID

Cas:14190-59-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:14190-59-1

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:1 Gram

FOB Price: $184.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

THIAZOLE-2-CARBOXYLIC ACID

Cas:14190-59-1

Min.Order:1 Gram

Negotiable

Type:Other

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Shanghai Minstar Chemical Co., Ltd

THIAZOLE-2-CARBOXYLIC ACID Basic information Product Name: THIAZOLE-2-CARBOXYLIC ACID Synonyms: 1,3-THIAZOLE-2-CARBOXYLIC ACID;RARECHEM AL BE 0750;THIAZOLE-2-CARBOXYLIC ACID;2-THIAZOLECARBOXYLIC ACID,THIAZOLE-2-CARBOXYLIC ACID;Thiazole-2-carbo

THIAZOLE-2-CARBOXYLIC ACID

Cas:14190-59-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Other

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratoryAppearance:Off-white to light yellow solid Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

THIAZOLE-2-CARBOXYLIC ACID cas no. 14190-59-1 97%

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Thiazole-2-Carboxylic Acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Other

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

Thiazole-2-carboxylic acid CAS 14190-59-1

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

2-Thiazolecarboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

THIAZOLE-2-CARBOXYLIC ACID

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

THIAZOLE-2-CARBOXYLIC ACID Storage:make to order Application:intermediate

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Thiazole-2-carboxylic acid cas 14190-59-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Thiazole-2-carboxylic acid cas 14190-59-1

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

Thiazole-2-Carboxylic Acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

14190-59-1 Application:intermediate

2-Thiazolecarboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Thiazole-2-carboxylic acid

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

THIAZOLE-2-CARBOXYLIC ACID 14190-59-1

Cas:14190-59-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-bromo-1,3-thiazole
3034-53-5

2-bromo-1,3-thiazole

carbon dioxide
124-38-9

carbon dioxide

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 2-bromo-1,3-thiazole With n-butyllithium In tetrahydrofuran
Stage #2: carbon dioxide
73%
Stage #1: 2-bromo-1,3-thiazole With n-butyllithium In diethyl ether; hexane at -78℃; for 0.166667h;
Stage #2: carbon dioxide In diethyl ether; hexane at -78℃; for 1.16667h;
64%
1,3-thiazole
288-47-1

1,3-thiazole

carbon dioxide
124-38-9

carbon dioxide

A

thiazole-5-carboxylic acid
14527-41-4

thiazole-5-carboxylic acid

B

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide With AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); potassium hydroxide In tetrahydrofuran at 20℃; under 1125.11 Torr; for 0.25h;
Stage #2: 1,3-thiazole In tetrahydrofuran at 20℃; under 1125.11 Torr; for 12h;
Stage #3: With hydrogenchloride In tetrahydrofuran; water regioselective reaction;
A 27%
B 61%
2-bromo-1,3-thiazole
3034-53-5

2-bromo-1,3-thiazole

water
7732-18-5

water

A

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

B

ETHYL 2-[N-(1'-AMINOCITRACONAMIDO)]-4-(2'-THIAZOLYL)PYRIMIDINE-5-CARBOXYLATE

ETHYL 2-[N-(1'-AMINOCITRACONAMIDO)]-4-(2'-THIAZOLYL)PYRIMIDINE-5-CARBOXYLATE

Conditions
ConditionsYield
With n-butyllithium; carbon dioxideA 57%
B n/a
thiazole-2-carboxylic acid ethyl ester
14527-42-5

thiazole-2-carboxylic acid ethyl ester

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: thiazole-2-carboxylic acid ethyl ester With potassium hydroxide; ethanol; water at 20℃; for 2h;
Stage #2: With hydrogenchloride; water In ethanol
25%
With potassium hydroxide
Stage #1: thiazole-2-carboxylic acid ethyl ester With potassium hydroxide; ethanol at 120℃; for 0.5h;
Stage #2: With hydrogenchloride; water In ethanol pH=4.0;
Stage #1: thiazole-2-carboxylic acid ethyl ester With potassium hydroxide; ethanol at 120℃; for 0.5h;
Stage #2: With hydrogenchloride In ethanol; water pH=4.0;
Stage #1: thiazole-2-carboxylic acid ethyl ester With potassium hydroxide; ethanol; water at 20℃; for 2h;
Stage #2: With hydrogenchloride; water
1,3-thiazole
288-47-1

1,3-thiazole

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
With diethyl ether; phenyllithium anschliessend Behandeln mit CO2;
2-bromo-1,3-thiazole
3034-53-5

2-bromo-1,3-thiazole

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
With n-butyllithium; diethyl ether anschliessend mit CO2;
thiocarboxamide
115-08-2

thiocarboxamide

formylchloroacetic acid ethyl ester

formylchloroacetic acid ethyl ester

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
beim anschliessenden Verseifen; reagirt analog mit 2-Chlor-acetessigsaeure-aethylester, 3-Chlor-laevulinsaeure-aethylester,;
C4H2NO2S(1-)*Li(1+)
1192365-76-6

C4H2NO2S(1-)*Li(1+)

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
With sulfuric acid; water
1,3-thiazole
288-47-1

1,3-thiazole

carbon dioxide
124-38-9

carbon dioxide

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 1,3-thiazole With n-butyllithium In tetrahydrofuran at -60℃; for 0.166667h;
Stage #2: carbon dioxide In tetrahydrofuran
Stage #1: 1,3-thiazole With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: carbon dioxide In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Inert atmosphere;
12 g
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

6-aminohexanoic acid phenylamide
115012-25-4

6-aminohexanoic acid phenylamide

thiazole-2-carboxylic acid (5-phenylcarbamoyl-pentyl)-amide

thiazole-2-carboxylic acid (5-phenylcarbamoyl-pentyl)-amide

Conditions
ConditionsYield
With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃;94%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

2-amino-phenol
95-55-6

2-amino-phenol

2-(thiazol-2-yl)benzo[d]oxazole

2-(thiazol-2-yl)benzo[d]oxazole

Conditions
ConditionsYield
With PS-PPh3; trichloroacetonitrile In acetonitrile at 150℃; for 0.25h; microwave irradiation;94%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

1-(3-amino-2,6-difluoro-phenyl)-ethanone
99724-35-3

1-(3-amino-2,6-difluoro-phenyl)-ethanone

thiazole-2-carboxylic acid (3-acetyl-2,4-difluoro-phenyl)-amide
746630-05-7

thiazole-2-carboxylic acid (3-acetyl-2,4-difluoro-phenyl)-amide

Conditions
ConditionsYield
With triethylamine; HATU In tetrahydrofuran92%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

3-(8-nitroquinolin-4-yl)benzenamine

3-(8-nitroquinolin-4-yl)benzenamine

N-(3-(8-nitroquinolin-4-yl)phenyl)thiazole-2-carboxamide

N-(3-(8-nitroquinolin-4-yl)phenyl)thiazole-2-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 0 - 20℃;92%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

ethyl potassium malonate
6148-64-7

ethyl potassium malonate

3-oxo-3-thiazol-2-yl-propionic acid ethyl ester
212621-63-1

3-oxo-3-thiazol-2-yl-propionic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 1,3-thiazole-2-carboxylic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 0 - 20℃; for 4h;
Stage #2: ethyl potassium malonate With magnesium chloride In tetrahydrofuran at 50 - 75℃; for 20h;
91%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

2-[5-amino-2-[(1r,4r)-4-(hydroxymethyl)cyclohexyl]indazol-6-yl]propan-2-ol

2-[5-amino-2-[(1r,4r)-4-(hydroxymethyl)cyclohexyl]indazol-6-yl]propan-2-ol

N-(2-((1r,4r)-4-(hydroxymethyl)cyclohexyl)-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl)thiazole-2-carboxamide

N-(2-((1r,4r)-4-(hydroxymethyl)cyclohexyl)-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl)thiazole-2-carboxamide

Conditions
ConditionsYield
With 2-chloro-1-methyl-pyridinium iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 0.5h; Inert atmosphere;91%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

1-(1-benzhydrylazetidin-3-yl)piperazine
930782-73-3

1-(1-benzhydrylazetidin-3-yl)piperazine

(4-(1-benzhydrylazetidin-3-yl)piperazin-1-yl)(thiazol-2-yl)methanone
1252779-95-5

(4-(1-benzhydrylazetidin-3-yl)piperazin-1-yl)(thiazol-2-yl)methanone

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane for 48h;90%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane for 48h; Inert atmosphere;90%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In water; N,N-dimethyl-formamide at 20℃; for 16h;78%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

2-Fluoroaniline
348-54-9

2-Fluoroaniline

N-(2-fluorophenyl)thiazole-2-carboxamide

N-(2-fluorophenyl)thiazole-2-carboxamide

Conditions
ConditionsYield
With pyridine; trichlorophosphate In dichloromethane at 20℃; Cooling with ice;79%
With pyridine; trichlorophosphate In dichloromethane at 20℃; Cooling with ice;79%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

4-chlorobenzoic acid hydrazide
536-40-3

4-chlorobenzoic acid hydrazide

N'-(4-chlorobenzoyl)thiazole-2-carbohydrazide

N'-(4-chlorobenzoyl)thiazole-2-carbohydrazide

Conditions
ConditionsYield
With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine In N,N-dimethyl-formamide at 20℃;73%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

1-(4-phenoxyphenyl)-4-(piperazin-1-yl)pyrrolidin-2-one hydrochloride

1-(4-phenoxyphenyl)-4-(piperazin-1-yl)pyrrolidin-2-one hydrochloride

1-(4-phenoxyphenyl)-4-(4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl)pyrrolidin-2-one

1-(4-phenoxyphenyl)-4-(4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl)pyrrolidin-2-one

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃;71%
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 10 - 35℃;170 mg
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

thiazole-2-carboxylic acid methoxy-methyl-amide
885278-18-2

thiazole-2-carboxylic acid methoxy-methyl-amide

Conditions
ConditionsYield
Stage #1: 1,3-thiazole-2-carboxylic acid With 2-chloro-4,6-dimethoxy-1 ,3,5-triazine In tetrahydrofuran at 0℃; for 0.25h;
Stage #2: With 4-methyl-morpholine In tetrahydrofuran at 20℃; for 1.5h;
Stage #3: N,O-dimethylhydroxylamine*hydrochloride In tetrahydrofuran at 0 - 20℃;
70%
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

N-(2'-chloro-5'-aminobenzoyl)-4-(p-fluorobenzy)-piperidine hydrochloride
944390-13-0

N-(2'-chloro-5'-aminobenzoyl)-4-(p-fluorobenzy)-piperidine hydrochloride

thiazole-2-carboxylic acid {4-chloro-3-[4-(4-fluoro-benzyl)-piperidine-1-carbonyl]-phenyl}-amide

thiazole-2-carboxylic acid {4-chloro-3-[4-(4-fluoro-benzyl)-piperidine-1-carbonyl]-phenyl}-amide

Conditions
ConditionsYield
Stage #1: 1,3-thiazole-2-carboxylic acid With N-ethyl-N,N-diisopropylamine; fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate In acetonitrile for 0.25h;
Stage #2: N-(2'-chloro-5'-aminobenzoyl)-4-(p-fluorobenzy)-piperidine hydrochloride With N-ethyl-N,N-diisopropylamine In acetonitrile for 2.25h;
69%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

potassium tert-butylate
865-47-4

potassium tert-butylate

tert-butyl thiazole-2-carboxylate

tert-butyl thiazole-2-carboxylate

Conditions
ConditionsYield
Stage #1: 1,3-thiazole-2-carboxylic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 23℃; for 5h;
Stage #2: potassium tert-butylate In dichloromethane; N,N-dimethyl-formamide at 23℃; for 1h; Temperature;
67%
Stage #1: 1,3-thiazole-2-carboxylic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 23℃; for 5h;
Stage #2: potassium tert-butylate In dichloromethane at 23℃; for 1h;
67%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

Demethylmifepristone
104004-96-8

Demethylmifepristone

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylthiazole-2-carboxamide

N-(4-((8S,11R,13S,14S,17S)-17-hydroxy-13-methyl-3-oxo-17-(prop-1-yn-1-yl)-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)phenyl)-N-methylthiazole-2-carboxamide

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h; Inert atmosphere;66%
N2-phenyl-5-amino-3-methyl-2,4-thiophenecarboxamide
331959-40-1

N2-phenyl-5-amino-3-methyl-2,4-thiophenecarboxamide

1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

3-methyl-N2-phenyl-5-(thiazole-2-carboxamido)thiophene-2,4-dicarboxamide

3-methyl-N2-phenyl-5-(thiazole-2-carboxamido)thiophene-2,4-dicarboxamide

Conditions
ConditionsYield
Stage #1: 1,3-thiazole-2-carboxylic acid With N-ethyl-N,N-diisopropylamine; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: N2-phenyl-5-amino-3-methyl-2,4-thiophenecarboxamide In N,N-dimethyl-formamide at 20℃;
66%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

hex-5-ynyl methanesulphonate
79496-61-0

hex-5-ynyl methanesulphonate

C10H11NO2S

C10H11NO2S

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 90℃; for 0.5h; Microwave irradiation;61%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

cloridrato del 2-amino-2-isobutirrilacetacetato di etile

cloridrato del 2-amino-2-isobutirrilacetacetato di etile

ethyl 5-methyl-3-oxo-2-(thiazole-2-carboxamido)hexanoate
910476-37-8

ethyl 5-methyl-3-oxo-2-(thiazole-2-carboxamido)hexanoate

Conditions
ConditionsYield
With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0℃; Molecular sieve;60%
With pyridine; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0℃; Molecular sieve;60%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

(S)-1-amino-N-(3-chloro-4-fluorophenyl)-7-fluoro-2,3-dihydro-1H-indene-4-carboxamide hydrochloride

(S)-1-amino-N-(3-chloro-4-fluorophenyl)-7-fluoro-2,3-dihydro-1H-indene-4-carboxamide hydrochloride

(S)-N-(4-((3-chloro-4-fluorophenyl)carbamoyl)-7-fluoro-2,3-dihydro-1H-inden-1-yl)thiazole-2-carboxamide

(S)-N-(4-((3-chloro-4-fluorophenyl)carbamoyl)-7-fluoro-2,3-dihydro-1H-inden-1-yl)thiazole-2-carboxamide

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In dichloromethane at 0 - 20℃; for 16h;60%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

4-methylthiosemicarbazide
6610-29-3

4-methylthiosemicarbazide

4-methyl-5-(1,3-thiazol-2-yl)-4H-1,2,4-triazole-3-thiol

4-methyl-5-(1,3-thiazol-2-yl)-4H-1,2,4-triazole-3-thiol

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In ethyl acetate; N,N-dimethyl-formamide at 20℃; Cooling with ice;59%
Stage #1: 1,3-thiazole-2-carboxylic acid; 4-methylthiosemicarbazide With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In ethyl acetate; N,N-dimethyl-formamide at 20℃; for 12h;
Stage #2: With sodium hydroxide for 0.666667h; Reflux;
Stage #1: 1,3-thiazole-2-carboxylic acid; 4-methylthiosemicarbazide With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine In ethyl acetate; N,N-dimethyl-formamide at 0 - 20℃;
Stage #2: With sodium hydroxide In ethyl acetate; N,N-dimethyl-formamide at 70℃;
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

C9H17NO3*2ClH

C9H17NO3*2ClH

ethyl 5-methyl-3-oxo-2-(thiazole-2-carboxamido)hexanoate
910476-37-8

ethyl 5-methyl-3-oxo-2-(thiazole-2-carboxamido)hexanoate

Conditions
ConditionsYield
Stage #1: C9H17NO3*2ClH With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide for 0.166667h;
Stage #2: 1,3-thiazole-2-carboxylic acid With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;
59%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

C9H10Cl2N2

C9H10Cl2N2

C13H11Cl2N3OS

C13H11Cl2N3OS

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 18h;57%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

(S)-3-[3-(4-fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidine
851882-63-8

(S)-3-[3-(4-fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidine

{(S)-3-[3-(4-fluoro-phenyl)-1,2,4-oxadiazol-5-yl]-piperidin-1-yl}-thiazol-2-yl-methanone

{(S)-3-[3-(4-fluoro-phenyl)-1,2,4-oxadiazol-5-yl]-piperidin-1-yl}-thiazol-2-yl-methanone

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; PS-DCC; N-ethyl-N,N-diisopropylamine In dichloromethane55%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

water
7732-18-5

water

zinc(II) acetate dihydrate
5970-45-6

zinc(II) acetate dihydrate

bis(κ2-N,O-thiazole-2-carboxylate)diaquazinc(II)
1270159-28-8

bis(κ2-N,O-thiazole-2-carboxylate)diaquazinc(II)

Conditions
ConditionsYield
In water High Pressure; metal:thiazole=2:1 molar ratio, heated at 90°C for 24 h; slowly cooled overnight, crysts. washed (ethanol), dried (N2 stream, room temp.); elem. anal., single cryst. XRD, TGA;55%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

2-phenyl-1,3-benzothiazol-5-amine
43087-91-8

2-phenyl-1,3-benzothiazol-5-amine

N-(2-phenylbenzo[d]thiazol-5-yl)thiazole-2-carboxamide

N-(2-phenylbenzo[d]thiazol-5-yl)thiazole-2-carboxamide

Conditions
ConditionsYield
Stage #1: 1,3-thiazole-2-carboxylic acid With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In tetrahydrofuran at 20℃; for 1.5h;
Stage #2: 2-phenyl-1,3-benzothiazol-5-amine In tetrahydrofuran
55%
Stage #1: 1,3-thiazole-2-carboxylic acid With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In tetrahydrofuran at 20℃; for 1.5h;
Stage #2: 2-phenyl-1,3-benzothiazol-5-amine In tetrahydrofuran
55%
1,3-thiazole-2-carboxylic acid
14190-59-1

1,3-thiazole-2-carboxylic acid

N1-(1,2,3,4-tetrahydroacridin-9-yl)hexane-1,6-diamine
249290-17-3

N1-(1,2,3,4-tetrahydroacridin-9-yl)hexane-1,6-diamine

C23H28N4OS

C23H28N4OS

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 12h;55%

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