DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
Cas:14631-20-0
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inquiryItems Standard Result Appearance A white or almost white crystalline powder Conforms Assay(HPLC)
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryN4-Acetylcytosine CAS 14631-20-0 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distrib
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/1019.html Product Name N4-Acetylcytosine CAS No. 14631-20-0
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inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
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inquiryTIANFUCHEM--14631-20-0--High purity N4-Acetylcytosine factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable bus
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inquiryN4-Acetylcytosine Basic information Product Name: N4-Acetylcytosine Synonyms: n-(1,2-dihydro-2-oxo-4-pyrimidinyl)-acetamid;N-ACETYLCYTOSINE;N4-ACETYLCYTOSINE;LABOTEST-BB LT00012625;4-Acetylamino-2-hydroxypyrimidine;N-Acetocytosine;N(4)-Acetylcy
Cas:14631-20-0
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inquiryN4-Acetylcytosine CAS:14631-20-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryN4-Acetylcytosine CAS NO:14631-20-0 CAS No.: 14631-20-0 Formular: C6H7N3O2 Molecular weight: 153.14 Appearance: a white or almost white crystalline powder Loss on drying: ≤1.0% Assay: ≥99% Application: R&D, intermediates. Storage: room te
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inquiryPRODUCT DETAILS
Cas:14631-20-0
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Sea/Air/Courier Port:Qingdao/Shanghai,China
Cas:14631-20-0
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryHubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:14631-20-0
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Conditions | Yield |
---|---|
With phosphoric acid at 100℃; for 8h; | 98% |
With pyridine for 2.5h; Heating; | 97.2% |
With pyridine at 20℃; for 24h; | 85% |
4-Amino-1-(2,5-anhydro-β-D-arabinofuranosyl)pyrimidin-2(1H)-one
A
4-N-Acetylcytosine
B
4-Acetamido-1-(2,3-di-O-acetyl-5-bromo-5-deoxy-β-D-arabinofuranosyl)pyrimidin-2(1H)-one
C
4-Amino-1-(5-bromo-5-deoxy-β-D-arabinofuranosyl)pyrimidin-2(1H)-one
Conditions | Yield |
---|---|
With hydrogen bromide In N,N-dimethyl-formamide at 120℃; for 0.416667h; | A 20% B 3% C 45% |
N-acetylcytidine
A
4-N-Acetylcytosine
B
N4,O5'-diacetyl-2',3'-dideoxycytidine
C
N4-acetyl-5'-O-(acetoxyisobutyryl)-2',3'-dideoxycytidine
Conditions | Yield |
---|---|
Yield given. Multistep reaction. Yields of byproduct given; |
N4-acetyl-O5'-trityl-2'deoxy-cytidine
A
4-N-Acetylcytosine
B
4,5-dihydro-5-trityloxymethylfuran-4-one
Conditions | Yield |
---|---|
With pyridine; chromium(VI) oxide; acetic anhydride In dichloromethane Ambient temperature; 45 - 60 min; |
4-N-Acetylcytosine
Conditions | Yield |
---|---|
With pyridine; dmap In dichloromethane at 20℃; Inert atmosphere; |
Conditions | Yield |
---|---|
100% |
4-N-Acetylcytosine
N-(1,2,2,2-tetrachloroethyl)benzamide
N-[1-(4-Acetylamino-2-oxo-2H-pyrimidin-1-yl)-2,2,2-trichloro-ethyl]-benzamide
Conditions | Yield |
---|---|
With sodium hydroxide In water; acetone at 0℃; for 0.5h; | 99% |
4-N-Acetylcytosine
1,2-di-O-acetyl-3-O-benzyl-4-C-methanesulfonyloxymethyl-5-O-methanesulfonyl-D-erythro-pentofuranose
(2R,3R,4S)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-4-(benzyloxy)-5,5-bis(((methylsulfonyl)oxy)methyl)tetrahydrofuran-3-yl acetate
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine; 1,2-di-O-acetyl-5-O-methanesulfonyl-4-C-methanesulfonyloxymethyl-3-O-benzyl-D-erythro-pentofuranose With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile for 1h; Reflux; Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 5.5h; Reflux; Inert atmosphere; | 96% |
Stage #1: 4-N-Acetylcytosine; 1,2-di-O-acetyl-5-O-methanesulfonyl-4-C-methanesulfonyloxymethyl-3-O-benzyl-D-erythro-pentofuranose With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile for 1h; Heating; Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 3h; Heating; Further stages.; | 82% |
With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate In acetonitrile | 82% |
Stage #1: 4-N-Acetylcytosine; 1,2-di-O-acetyl-5-O-methanesulfonyl-4-C-methanesulfonyloxymethyl-3-O-benzyl-D-erythro-pentofuranose With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile at 40℃; for 0.333333h; Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile at 20℃; for 2.5h; Heating / reflux; | 60% |
4-N-Acetylcytosine
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-(methylcarbonyloxy)-1,3-oxathiolane-2-carboxylate
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-[4-(methylcarboxamido)-2-oxo-1,2-dihydro-1-pyrimidinyl]-1,3-oxathiolane-2-carboxylate
Conditions | Yield |
---|---|
Stage #1: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-(methylcarbonyloxy)-1,3-oxathiolane-2-carboxylate With triethylsilane; iodine In dichloromethane at 0℃; for 1h; Inert atmosphere; Stage #2: 4-N-Acetylcytosine With N,O-bis-(trimethylsilyl)-acetamide In dichloromethane at 0 - 20℃; for 1h; Reagent/catalyst; Inert atmosphere; stereoselective reaction; | 95% |
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide for 18h; Ambient temperature; | 91% |
4-N-Acetylcytosine
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine; 5-((tert-butyl(diphenyl)silyl)oxy)-5,7-dimethoxy-2,3,5,7-tetrahydro[1,4]dithiino[2,3-c]furan With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile at 50℃; for 0.5h; Vorbrueggen Nucleoside Synthesis; Inert atmosphere; Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile at 20℃; for 0.166667h; Inert atmosphere; | 91% |
4-N-Acetylcytosine
5-O-benzoyl-3-deoxy-1,2-di-O-acetyl-α,β-D-erythro-pentofuranose
3'-deoxycytidine
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine; 5-O-benzoyl-3-deoxy-1,2-di-O-acetyl-α,β-D-erythro-pentofuranose With benzenesulfonamide In acetonitrile for 1h; Heating; Stage #2: With trimethylsilyl trifluoromethanesulfonate at 20℃; for 5h; Stage #3: With ammonium hydroxide In tetrahydrofuran; methanol at 50℃; for 6h; Further stages.; | 90% |
Conditions | Yield |
---|---|
With potassium carbonate; dimethyl sulfoxide In tetrahydrofuran at 20℃; for 22h; Alkylation; | 88% |
4-N-Acetylcytosine
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane In toluene for 3h; Heating / reflux; Stage #2: 2-deoxy-2,2-difluoro-3-benzoyl-5-(2-naphthoyl)-1-methanesulfonyloxy-D-ribofuranose With trimethylsilyl trifluoromethanesulfonate In toluene for 15h; Heating / reflux; | 88% |
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In chloroform at 100℃; | 88% |
4-N-Acetylcytosine
1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane
Conditions | Yield |
---|---|
With caesium carbonate In dimethyl sulfoxide at 20℃; for 24h; Schlenk technique; Inert atmosphere; Irradiation; | 87% |
Conditions | Yield |
---|---|
With benzenesulfonamide; trimethylsilyl trifluoromethanesulfonate In acetonitrile at 65℃; | 86% |
Substitution; | 86% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 24h; | 86% |
4-N-Acetylcytosine
1,4-anhydro-2-deoxy-3,5-di-O-(di-tert-butylsilylene)-1-C-(triethylsilyloxy-methyl)-D-erythro-pent-1-enitol
N4-acetyl-1-[3,5-O-(di-tert-butylsilylene)-2-deoxy-2-iodo-1-C-(triethyl-silyloxymethyl)-β-D-ribofuranosyl]cytosine
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile Stage #2: 1,4-anhydro-2-deoxy-3,5-di-O-(di-tert-butylsilylene)-1-C-(triethylsilyloxy-methyl)-D-erythro-pent-1-enitol With N-iodo-succinimide In dichloromethane; acetonitrile at 0℃; for 12h; Inert atmosphere; stereoselective reaction; | 84% |
4-N-Acetylcytosine
ethyl acrylate
ethyl 3-(4-acetamido-2-oxopyrimidin-1(2H)-yl)propanoate
Conditions | Yield |
---|---|
With tetrabutylammomium bromide; zinc(II) oxide at 100℃; for 0.416667h; Michael addition; microwave irradiation; | 83% |
With tetrabutylammomium bromide at 100℃; for 0.416667h; Microwave irradiation; Neat (no solvent); | 81% |
With Bacillus subtilis alkaline protease EC 3.4.21.14 In dimethyl sulfoxide at 50℃; for 24h; Michael addition; | 28.7% |
Conditions | Yield |
---|---|
With triethylamine In water at 100℃; for 0.0833333h; Michael addition; microwave irradiation; | 83% |
4-N-Acetylcytosine
(E)-4-bromo-2-benzoyloxymethyl-1-fluorobut-1-ene
(E)-4-(4-acetylaminopyrimidinone-1-yl)-2-benzoyloxymethyl-1-fluorobut-1-ene
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 18h; | 81% |
4-N-Acetylcytosine
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine With bis-(trimethylsilyl)acetamide In acetonitrile at 20℃; for 0.5h; Stage #2: 3-[(tert-butyldiphenylsilyloxy)methyl]-2-methylisoxazolidin-5-yl acetate; trimethylsilyl trifluoromethanesulfonate In acetonitrile at 20℃; for 24h; Further stages.; | A 80% B 10% |
Conditions | Yield |
---|---|
With copper acetylacetonate; di-tert-butyl peroxide; N,N-dimethyl-formamide at 100℃; for 10h; Green chemistry; | 79% |
4-N-Acetylcytosine
C7H10O3S2
{5-(4-(methylcarboxamido)-2-oxo-1,2-dihydro-1-pyrimidinyl)-5,6-dihydro-1,4-dithiin-2-yl}methyl acetate
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine With trimethylsilyl trifluoromethanesulfonate; triethylamine In dichloromethane at 0 - 20℃; Pummerer type glycosidation; Inert atmosphere; Stage #2: C7H10O3S2 In dichloromethane at 0 - 20℃; Pummerer type glycosidation; Inert atmosphere; | 78% |
2,3,4,6-tetra-O-benzoylglucosyl bromide
4-N-Acetylcytosine
Conditions | Yield |
---|---|
With mercury(II) cyanide In nitromethane for 4.5h; Heating; | 77% |
4-N-Acetylcytosine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 2h; | 76% |
4-N-Acetylcytosine
1,4-anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-sulfinyl-D-ribitol
N4-acetyl-1-[2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-β-D-ribofuranosyl]cytosine
Conditions | Yield |
---|---|
With trimethylsilyl trifluoromethanesulfonate In dichloromethane; toluene at 20℃; for 0.0833333h; Pummerer reaction; | 75% |
4-N-Acetylcytosine
1-bromo-hexane
N-(1-hexyl-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 16h; | 75% |
4-N-Acetylcytosine
chloroacetic acid ethyl ester
N4-acetyl-1-(ethoxycarbonylmethyl)cytosine
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 5h; Heating; | 75% |
4-N-Acetylcytosine
C7H10O3S2
{6-(4-(methylcarboxamido)-2-oxo-1,2-dihydro-1-pyrimidinyl)-5,6-dihydro-1,4-dithiin-2-yl}methyl acetate
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine With trimethylsilyl trifluoromethanesulfonate; triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere; Stage #2: C7H10O3S2 In dichloromethane at 0 - 20℃; Inert atmosphere; | 75% |
4-N-Acetylcytosine
1,2,3,5-tetra-O-benzoyl-2-C-trimethylsilylethynyl-β-D-ribofuranose
N4-acetyl-2',3',5'-tri-O-benzoyl-2'-C-[(trimethylsilyl)ethynyl]cytidine
Conditions | Yield |
---|---|
With N,O-bis-(trimethylsilyl)-acetamide; tin(IV) chloride In acetonitrile for 3.5h; Heating; | 73% |
4-N-Acetylcytosine
1-dodecylbromide
N-(1-dodecyl-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
Conditions | Yield |
---|---|
Stage #1: 4-N-Acetylcytosine With potassium carbonate In N,N-dimethyl-formamide for 0.5h; Stage #2: 1-dodecylbromide In N,N-dimethyl-formamide at 80℃; for 24h; | 71% |
4-N-Acetylcytosine
1-(t-butyl-dimethylsilyloxymethyl)-3(R,S)-hydroxybicyclo[2,1,1]hexane
N-{1-[4-(tert-butyl-dimethyl-silanyloxymethyl)-bicyclo[2.1.1]hex-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-acetamide
Conditions | Yield |
---|---|
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; Condensation; Mitsunobu reaction; | 70% |
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