CAS No.149606-27-9,(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide Suppliers

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Auristatin PE CAS NO.149606-27-9

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-but

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

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Antimex Chemical Limied

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L-Valinamide,N,N-dimethyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[(2-phenylethyl)amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

Soblitodin

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Hangzhou Fandachem Co.,Ltd

(2S)-2-[[(2S)-2-DIMETHYLAMINO-3-METHYL-BUTANOYL]AMINO]-N-[(3R,4S,5S)-3 -METHOXY-1-[(3R)-3-[(1R,2R)-1-METHOXY-2-(PHENETHYLCARBAMOYL)PROPYL]PYR ROLIDIN-1-YL]-5-METHYL-1-OXO-HEPTAN-4-YL]-N,3-DIMETHYL-BUTAppearance:white crystalline powder Storage:Store

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Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

SOBLIDOTIN

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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

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NUTROCHEM- MANUFACTURE PLACE

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Wuhan Sun-shine Bio-technology Corporation Limited

Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel，pharmaceutical intermediates，fine Chemicals production and customization. Company has strong ability of research and development

Auristatin PEwith factory price

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Synthetic route

: 64-04-0
phenethylamine

: 163768-53-4
Dov-Val-Dil-Dap

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
With diethyl cyanophosphonate; triethylamine In N,N-dimethyl-formamide Yield given;
With triethylamine; diethyl cyano phosphate In DMF (N,N-dimethyl-formamide)

: 135383-56-1
(3R,4S,5S)-4--3-methoxy-5-methylheptanoic acid

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 9 steps 1: H2SO4 / CH2Cl2 2: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 3: 1,3-dicyclohexylcarbodiimide / CH2Cl2 4: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 5: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 6: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 7: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 8: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 9: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

Yield

Multi-step reaction with 9 steps
1: H2SO4 / CH2Cl2
2: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
3: 1,3-dicyclohexylcarbodiimide / CH2Cl2
4: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
5: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
6: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
7: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
8: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
9: diethyl phosphorocyanidate, Et3N / dimethylformamide
View Scheme

: 120205-58-5
tert-Butyl (3R,4S,5S)-3-methoxy-4--5-methylheptanoate

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 8 steps 1: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 2: 1,3-dicyclohexylcarbodiimide / CH2Cl2 3: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 4: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 5: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 6: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 7: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 8: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

Yield

Multi-step reaction with 8 steps
1: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
2: 1,3-dicyclohexylcarbodiimide / CH2Cl2
3: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
4: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
5: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
6: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
7: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
8: diethyl phosphorocyanidate, Et3N / dimethylformamide
View Scheme

: 474645-22-2
tert-Butyl (3R,4S,5S)-3-methoxy-4-(N-methylamino)-5-methylheptanoate

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1: 1,3-dicyclohexylcarbodiimide / CH2Cl2 2: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 3: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 4: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 5: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 6: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 7: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

Yield

Multi-step reaction with 7 steps
1: 1,3-dicyclohexylcarbodiimide / CH2Cl2
2: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
3: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
4: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
5: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
6: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
7: diethyl phosphorocyanidate, Et3N / dimethylformamide
View Scheme

: 120205-53-0
(3R,4S,5S)-tert-butyl 4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoate

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 2: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 3: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 4: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

: 120205-52-9
tert-butyl (3R,4S,5S)-4-[(2S)-2-[[(benzyloxy)carbonyl]amino]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 2: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 3: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 4: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 5: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 6: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

Yield

Multi-step reaction with 6 steps
1: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
2: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
3: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
4: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
5: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
6: diethyl phosphorocyanidate, Et3N / dimethylformamide
View Scheme

: 163768-52-3
Dov-Val-Dil-Dap-OBzl

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 2: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

: 177423-00-6
(3R,4S,5S)-4-[(2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 2: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 3: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 4: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 5: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

: 149664-79-9
(3R,4S,5S)-4-(Benzyloxycarbonyl-methyl-amino)-3-methoxy-5-methyl-heptanoic acid methyl ester

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 10 steps 1: 1N aq. NaOH / dioxane / 3 h / Ambient temperature 2: H2SO4 / CH2Cl2 3: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 4: 1,3-dicyclohexylcarbodiimide / CH2Cl2 5: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 6: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 7: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature 8: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 9: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 10: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

Yield

Multi-step reaction with 10 steps
1: 1N aq. NaOH / dioxane / 3 h / Ambient temperature
2: H2SO4 / CH2Cl2
3: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
4: 1,3-dicyclohexylcarbodiimide / CH2Cl2
5: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
6: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
7: trifluoroacetic acid / CH2Cl2 / 1 h / Ambient temperature
8: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h
9: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h
10: diethyl phosphorocyanidate, Et3N / dimethylformamide
View Scheme

: 133120-89-5
(3R,4S,5S)-4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoic acid

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: diethyl phosphorocyanidate, Et3N / dimethylformamide / a) 0 deg C, 2 h, b) RT, 16 h 2: H2 / 5percent Pd/C / 2-methyl-propan-2-ol; H2O / 2 h 3: diethyl phosphorocyanidate, Et3N / dimethylformamide View Scheme

: 3-methoxy-2-methyl-N-phenethyl-3-pyrrolidin-2-yl-propionamide

: 133120-89-5
(3R,4S,5S)-4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoic acid

: 149606-27-9
TZT-1027

Conditions

Conditions	Yield
With triethylamine; diethyl cyano phosphate In DMF (N,N-dimethyl-formamide)

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