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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-Ethynyl-3,5-dimethoxybenzene Manufacturer/High quality/Best price/In stock

Cas:171290-52-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

High quality 1-Ethylnyl-3,5-dimethoxybenzene CAS 171290-52-1 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates,

High quality 1-Ethylnyl-3,5-dimethoxybenzene CAS 171290-52-1 with factory price

Cas:171290-52-1

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Now we would like to update our product list for you, kindly check the below information: 1. Catalyst series ( such as Noble Metal Catalyst, Phosphorous ligand, etc ) 2. Pharmaceutical Intermediate ( such as diabtes series, Anti

171290-52-1

Cas:171290-52-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 171290-52-1 with competitive price

Cas:171290-52-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Ethynyl-3,5-dimethoxybenzene 171290-52-1

Cas:171290-52-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98 CAS:171290-52-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qual

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98 CAS:171290-52-1

Cas:171290-52-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Ethynyl-3,5-dimethoxybenzene

Cas:171290-52-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:171290-52-1

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3,5-dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98 CAS:171290-52-1

Cas:171290-52-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,5-dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzene, 1-ethynyl-3,5-dimethoxy-

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-Ethynyl-3,5-dimethoxybenzene/High quality

Cas:171290-52-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-ethynyl-3,5-dimethoxybenzene

Cas:171290-52-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3,5-dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

3,5-dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

3,5-Dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98

Cas:171290-52-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98

Cas:171290-52-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

3,5-dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

3,5-dimethoxyphenylacetylene

Cas:171290-52-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,5-Dimethoxyphenyl acetylene cas no. 171290-52-1 98%

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1-Ethynyl-3,5-dimethoxybenzene

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3,5-DiMethoxyphenylacetylene

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-Phenethyl isothiocyanate

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemsigma International Co.,Ltd.

bulk productiongoods in stockswe have the best competitive price in the marketmeantime,we are committed to service to our every customer Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical

1-ETHYNYL-3 5-DIMETHOXYBENZENE 98

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzene,1-ethynyl-3,5-dimethoxy-

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

1-Ethylnyl-3,5-dimethoxybenzene

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

1-Ethynyl-3,5-dimethoxybenzene

Cas:171290-52-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

1-(3,5-dimethoxyphenyl)-2-(trimethylsilyl)acetylene
400608-30-2

1-(3,5-dimethoxyphenyl)-2-(trimethylsilyl)acetylene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 0.0833333h;100%
With potassium carbonate In methanol at 20℃; for 2h;96%
With potassium carbonate In methanol at 20℃; for 2h;96%
1-(2,2-dibromoethen-1-yl)-3,5-dimethoxybenzene
205746-51-6

1-(2,2-dibromoethen-1-yl)-3,5-dimethoxybenzene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
With n-butyllithium for 10h;94%
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1.5h;86%
With n-butyllithium In tetrahydrofuran; hexane at -50℃; Schlenk technique; Inert atmosphere;81%
2-methyl-4-(3,5-dimethoxyphenyl)-3-butyn-2-ol
171290-51-0

2-methyl-4-(3,5-dimethoxyphenyl)-3-butyn-2-ol

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
With potassium hydroxide In toluene at 65℃; for 24h;85%
With potassium hydroxide at 100 - 135℃; Yield given;
With potassium hydroxide In toluene for 24h; Reflux; Inert atmosphere;
3,5-dimethoxybenzaldehdye
7311-34-4

3,5-dimethoxybenzaldehdye

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate
90965-06-3

dimethyl 1-(1-diazo-2-oxopropyl)phosphonate

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
With potassium carbonate In methanol at 20℃; for 12h; Inert atmosphere;57%
1-(3,5-dimethoxyphenyl)ethan-1-one
39151-19-4

1-(3,5-dimethoxyphenyl)ethan-1-one

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
With diethyl chlorophosphate; lithium diisopropyl amide Yield given. Multistep reaction;
1-iodo-3,5-dimethoxybenzene
25245-27-6

1-iodo-3,5-dimethoxybenzene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / Pd(PPh3)2Cl2; CuI; PPh3 / triethylamine / 48 h / 50 °C
2: 100 percent / TBAF / tetrahydrofuran / 0.08 h
View Scheme
Multi-step reaction with 2 steps
1: Et3N, pyridine, Ph3P, CuI / (Ph3P)2PdCl2 / 14 h / 25 °C
2: KOH / 100 - 135 °C
View Scheme
Multi-step reaction with 2 steps
1: copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / 20 °C / Inert atmosphere
2: potassium fluoride; methanol / 2 h / 20 °C
View Scheme
3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aq. HCl; NaNO2 / 0 °C
1.2: 50 percent / aq. KI / 20 °C
2.1: 85 percent / Pd(PPh3)2Cl2; CuI; PPh3 / triethylamine / 48 h / 50 °C
3.1: 100 percent / TBAF / tetrahydrofuran / 0.08 h
View Scheme
Multi-step reaction with 4 steps
1: hydrogenchloride; sodium nitrite / water / -10 - 5 °C / Cooling with acetone-dry ice
2: potassium iodide / water / 20 °C
3: copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / 20 °C / Inert atmosphere
4: potassium fluoride; methanol / 2 h / 20 °C
View Scheme
3,5-dimethoxybenzoic acid
1132-21-4

3,5-dimethoxybenzoic acid

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2.) trimethylchlorosilane, 3.) 0.5 N HCl
2: 1.) LDA, 2.) diethyl chlorophosphate, 3.) LDA
View Scheme
carbon tetrabromide
558-13-4

carbon tetrabromide

3,5-dimethoxybenzaldehdye
7311-34-4

3,5-dimethoxybenzaldehdye

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Stage #1: carbon tetrabromide; 3,5-dimethoxybenzaldehdye With triphenylphosphine In dichloromethane at 0 - 20℃; for 0.5h; Ramirez-Corey-Fuchs reaction;
Stage #2: With lithium diisopropyl amide In tetrahydrofuran; n-heptane; ethylbenzene at -78℃; for 2h; Ramirez-Corey-Fuchs reaction;
Stage #3: With ammonium chloride In tetrahydrofuran; n-heptane; ethylbenzene Ramirez-Corey-Fuchs reaction;
72 mg
3,5-dimethoxybenzaldehdye
7311-34-4

3,5-dimethoxybenzaldehdye

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triphenylphosphine / dichloromethane / 0.5 h / 0 - 20 °C
2: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 2 h / -78 °C
View Scheme
Multi-step reaction with 2 steps
1.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere; Schlenk technique
1.2: Inert atmosphere; Schlenk technique
2.1: n-butyllithium / tetrahydrofuran; hexane / -50 °C / Schlenk technique; Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: triphenylphosphine / dichloromethane / 1.25 h / 0 °C / Inert atmosphere; Schlenk technique
2: caesium carbonate / dimethyl sulfoxide / 115 °C / Sealed tube; Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: triphenylphosphine / dichloromethane / 2 h / 0 °C / Inert atmosphere
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: triphenylphosphine / dichloromethane / 0.5 h / 0 - 5 °C
1.2: 16 h / 20 °C
2.1: n-butyllithium / hexane; tetrahydrofuran / 16.5 h / Inert atmosphere
View Scheme
1-bromo-3,5-dimethoxybenzene
20469-65-2

1-bromo-3,5-dimethoxybenzene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tris-(dibenzylideneacetone)dipalladium(0); (dimethylamino)trimethyltin; triphenylphosphine / toluene / 8 h / Inert atmosphere; Reflux
2: tetrabutyl ammonium fluoride / dichloromethane / 5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: triphenylphosphine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 24 h / Reflux; Inert atmosphere
2: potassium hydroxide / toluene / 24 h / 65 °C
View Scheme
Multi-step reaction with 2 steps
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / N,N-dimethyl-formamide / 12 h / 80 °C / Inert atmosphere
2: potassium carbonate / methanol / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / N,N-dimethyl-formamide / 12 h / 80 °C / Inert atmosphere
2: potassium carbonate / methanol / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 24 h / Reflux; Inert atmosphere
2: potassium hydroxide / toluene / 24 h / Reflux; Inert atmosphere
View Scheme
3,5-Dimethoxy-benzenediazonium; chloride
86988-56-9

3,5-Dimethoxy-benzenediazonium; chloride

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium iodide / water / 20 °C
2: copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / 20 °C / Inert atmosphere
3: potassium fluoride; methanol / 2 h / 20 °C
View Scheme
3,5-dimethoxyphenethyl alcohol
7417-20-1

3,5-dimethoxyphenethyl alcohol

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate; fluorosulfonyl fluoride; dimethyl sulfoxide / 2 h / 20 °C
2: cesium fluoride / dimethyl sulfoxide / 2 h / 100 °C
View Scheme
C10H11FO5S

C10H11FO5S

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
With cesium fluoride In dimethyl sulfoxide at 100℃; for 2h;224 mg
4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

Conditions
ConditionsYield
Sonogashira Cross-Coupling;
1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine
1001070-33-2

1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

1-(benzenesulfonyl)-5-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrrolo[2,3-b]pyridine

1-(benzenesulfonyl)-5-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrrolo[2,3-b]pyridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In acetonitrile at 80℃; for 1.5h; Inert atmosphere; Sealed tube;100%
(Z)-N-benzylidenebenzylamine N-oxide
77681-22-2, 3376-26-9, 85225-56-5

(Z)-N-benzylidenebenzylamine N-oxide

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

N-benzyl-N-(3-(3,5-dimethoxyphenyl)-1-phenylprop-2-yn-1-yl)-hydroxylamine

N-benzyl-N-(3-(3,5-dimethoxyphenyl)-1-phenylprop-2-yn-1-yl)-hydroxylamine

Conditions
ConditionsYield
Stage #1: (Z)-N-benzylidenebenzylamine N-oxide; 1-Ethynyl-3,5-dimethoxy-benzene With trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; zinc dibromide In diethyl ether at 20℃; for 2h; Inert atmosphere;
Stage #2: With toluene-4-sulfonic acid In methanol for 2h;
100%
para-iodoanisole
696-62-8

para-iodoanisole

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

1,3-dimethoxy-5-((4-methoxyphenyl)ethynyl)benzene
400608-31-3

1,3-dimethoxy-5-((4-methoxyphenyl)ethynyl)benzene

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 18h; Sonogashira coupling; Inert atmosphere;99%
With copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride at 20℃; for 6h; Inert atmosphere;93%
With pyrrolidine; palladium diacetate; triphenylphosphine for 1h; Sonogashira Cross-Coupling; Inert atmosphere; Reflux;93%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 0 - 20℃; for 18h; Inert atmosphere; Schlenk technique;80%
With pyrrolidine; triphenylphosphine; palladium 10% on activated carbon at 85℃; for 17h; Sonogashira Coupling; Inert atmosphere;75%
1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

(2R,3S)-5β-azido-2-{[(4-methylbenzoyl)oxy]methyl}tetrahydrofuran-3-yl 4-methylbenzoate
234106-08-2

(2R,3S)-5β-azido-2-{[(4-methylbenzoyl)oxy]methyl}tetrahydrofuran-3-yl 4-methylbenzoate

1-[2′-deoxy-3′,5′-bis{O-(p-toluoyl)}-β-D-ribofuranosyl]-4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazole
1416717-98-0

1-[2′-deoxy-3′,5′-bis{O-(p-toluoyl)}-β-D-ribofuranosyl]-4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazole

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; water at 75 - 80℃; Inert atmosphere;99%
N-(tert-butoxycarbonyl)-1,4-dihydro-1,4-iminonaphthalene
5176-28-3

N-(tert-butoxycarbonyl)-1,4-dihydro-1,4-iminonaphthalene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

C25H27NO4

C25H27NO4

Conditions
ConditionsYield
Stage #1: N-(tert-butoxycarbonyl)-1,4-dihydro-1,4-iminonaphthalene With (R)-1-[(Sp)-2-(dicyclohexylphosphanyl)ferrocenylethyl]diphenylphosphane; rhodium(III) chloride trihydrate In 1,2-dimethoxyethane at 20℃; for 0.333333h; Inert atmosphere; Schlenk technique;
Stage #2: 1-Ethynyl-3,5-dimethoxy-benzene In 1,2-dimethoxyethane at 70℃; for 30h; Inert atmosphere; Schlenk technique; enantioselective reaction;
98%
N-(tert-butoxycarbonyl)-1,4-dihydro-1,4-iminonaphthalene
5176-28-3

N-(tert-butoxycarbonyl)-1,4-dihydro-1,4-iminonaphthalene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

tert-butyl ((1R,2S)-2-((3,5-dimethoxyphenyl)ethynyl)-1,2-dihydronaphthalen-1-yl)carbamate
1575707-08-2

tert-butyl ((1R,2S)-2-((3,5-dimethoxyphenyl)ethynyl)-1,2-dihydronaphthalen-1-yl)carbamate

Conditions
ConditionsYield
Stage #1: N-(tert-butoxycarbonyl)-1,4-dihydro-1,4-iminonaphthalene With (R)-(+)-2,2'-bis[bis(3,5-dimethylphenyl)phosphino]-1,1'-binaphthyl; copper(I) trifluoromethanesolfonate toluene complex; palladium diacetate In 1,2-dimethoxyethane at 0 - 20℃; for 0.5h; Inert atmosphere; Schlenk technique;
Stage #2: 1-Ethynyl-3,5-dimethoxy-benzene In 1,2-dimethoxyethane for 6h; Inert atmosphere; Schlenk technique;
98%
3-azido-N-(3-(trifluoromethyl)phenyl)benzamide

3-azido-N-(3-(trifluoromethyl)phenyl)benzamide

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

3-(4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl)-N-(3-(trifluoromethyl)phenyl)benzamide

3-(4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl)-N-(3-(trifluoromethyl)phenyl)benzamide

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate In water; tert-butyl alcohol at 20℃; for 2h; Inert atmosphere;98%
With copper(II) sulfate; sodium L-ascorbate In water; tert-butyl alcohol at 20℃; for 2h;98%
methyl 3-formyl-2-(2-iodophenyl)indolizine-1-carboxylate

methyl 3-formyl-2-(2-iodophenyl)indolizine-1-carboxylate

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

methyl 2-(2-((3,5-dimethoxyphenyl)ethynyl)phenyl)-3-formylindolizine-1-carboxylate

methyl 2-(2-((3,5-dimethoxyphenyl)ethynyl)phenyl)-3-formylindolizine-1-carboxylate

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile at 100℃; for 2h; Sonogashira Cross-Coupling;98%
C154H267N11O42
942620-37-3

C154H267N11O42

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

C162H273O42N11O2CH2CH2

C162H273O42N11O2CH2CH2

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate In water; tert-butyl alcohol for 0.166667h; microwave irradiation;97%
2-methoxy-1,4-benzoquinone
2880-58-2

2-methoxy-1,4-benzoquinone

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

4-((3,5-dimethoxyphenyl)ethynyl)-4-hydroxy-3-methoxycyclohexa-2,5-dien-1-one
1193360-00-7

4-((3,5-dimethoxyphenyl)ethynyl)-4-hydroxy-3-methoxycyclohexa-2,5-dien-1-one

Conditions
ConditionsYield
Stage #1: 1-Ethynyl-3,5-dimethoxy-benzene With n-butyllithium In tetrahydrofuran at -78℃; for 0.0833333h; Inert atmosphere;
Stage #2: 2-methoxy-1,4-benzoquinone In tetrahydrofuran at -78℃; for 0.25h; Inert atmosphere;
96%
Stage #1: 1-Ethynyl-3,5-dimethoxy-benzene With n-butyllithium In tetrahydrofuran; hexane at -78℃;
Stage #2: 2-methoxy-1,4-benzoquinone In tetrahydrofuran; hexane at -78℃;
Stage #3: With water; ammonium chloride In tetrahydrofuran; hexane
ortho-bromobenzaldehyde
6630-33-7

ortho-bromobenzaldehyde

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

2-((3,5-dimethoxyphenyl)ethynyl)benzaldehyde
1078710-66-3

2-((3,5-dimethoxyphenyl)ethynyl)benzaldehyde

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 50℃; for 6h; Sonogashira coupling;96%
With copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine In tetrahydrofuran at 80℃; for 12h;
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 60℃; for 4h; Inert atmosphere;
1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

2,2-dipivaloylamino-4-methyl-5-iodo-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine
306315-01-5

2,2-dipivaloylamino-4-methyl-5-iodo-7-(N-benzyl)pyrrolo[2,3-d]pyrimidine

N-{7-benzyl-4-methyl-5-[(3,5-dimethoxyphenyl)ethynyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}-N-(2,2-dimethylpropanoyl)-2,2-dimethylpropanamide
1321913-92-1

N-{7-benzyl-4-methyl-5-[(3,5-dimethoxyphenyl)ethynyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}-N-(2,2-dimethylpropanoyl)-2,2-dimethylpropanamide

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In 1,1-dichloroethane at 20℃; for 24h; Sonogashira coupling; Inert atmosphere; Darkness;96%
5-(azidomethyl)-3-(3,4-dimethoxyphenyl)isoxazole

5-(azidomethyl)-3-(3,4-dimethoxyphenyl)isoxazole

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

3-(3,4-dimethoxyphenyl)-5-((4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl)methyl)isoxazole

3-(3,4-dimethoxyphenyl)-5-((4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl)methyl)isoxazole

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate In water; N,N-dimethyl-formamide at 70℃; for 0.166667h; Sealed tube; Microwave irradiation;96%
8-bromo-2'-deoxyadenosine
14985-44-5

8-bromo-2'-deoxyadenosine

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

2-(6-amino-8-((3,5-dimethoxyphenyl)ethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
1350627-76-7

2-(6-amino-8-((3,5-dimethoxyphenyl)ethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 20℃; for 18h; Sonogashira coupling; Inert atmosphere;95%
1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

(2R,3S)-5α-azido-2-{[(4-methylbenzoyl)oxy]methyl}tetrahydrofuran-3-yl 4-methylbenzoate
316354-49-1

(2R,3S)-5α-azido-2-{[(4-methylbenzoyl)oxy]methyl}tetrahydrofuran-3-yl 4-methylbenzoate

C31H31N3O7

C31H31N3O7

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate; diisopropylamine In tetrahydrofuran; water at 75 - 80℃; for 12h; Inert atmosphere;95%
Dimethylphenylsilane
766-77-8

Dimethylphenylsilane

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

((3,5-dimethoxyphenyl)ethynyl)dimethyl(phenyl)silane

((3,5-dimethoxyphenyl)ethynyl)dimethyl(phenyl)silane

Conditions
ConditionsYield
With sodium hydroxide In 1,2-dimethoxyethane at 65℃; for 48h;95%
benzyl azide
622-79-7

benzyl azide

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

1-benzyl-4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazole

1-benzyl-4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazole

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; betaine; sodium L-ascorbate In water at 30℃; for 24h;95%
methyl 5-azido-2-hydroxybenzoate
1239028-02-4

methyl 5-azido-2-hydroxybenzoate

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate
1239028-26-2

methyl 2-hydroxy-5-[4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]benzoate

Conditions
ConditionsYield
With copper(II) sulfate; sodium L-ascorbate In water; dimethyl sulfoxide; tert-butyl alcohol at 20℃; for 96h; Inert atmosphere;94%
1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

(E)-2,2'-(but-1-en-3-yne-1,4-diyl)bis(2,6-dimethoxybenzene)
1261302-47-9

(E)-2,2'-(but-1-en-3-yne-1,4-diyl)bis(2,6-dimethoxybenzene)

Conditions
ConditionsYield
With C77H74N2OPtSi2 In toluene at 60℃; Reagent/catalyst; Inert atmosphere; diastereoselective reaction;94%
With [{Pd(μ-OH)Cl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)}2]; potassium hydroxide In ethanol at 22℃; for 24h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Schlenk technique; stereoselective reaction;94%
With CoH(P(CH3)3)4 In tetrahydrofuran at 20℃; for 2h; Schlenk technique; Inert atmosphere; stereoselective reaction;63%
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; acetic acid In tetrahydrofuran; methanol; water at 20℃; for 7h; Inert atmosphere; optical yield given as %de; stereoselective reaction;0.116 g
3-chloro-6-methoxypyridazine
1722-10-7

3-chloro-6-methoxypyridazine

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

3-[(3,5-dimethoxyphenyl)ethynyl]-6-methoxypyridazine

3-[(3,5-dimethoxyphenyl)ethynyl]-6-methoxypyridazine

Conditions
ConditionsYield
With dichloro bis(acetonitrile) palladium(II); dicyclohexyl(2',4',6'-triisopropyl-[1,1':3',1''-terphenyl]-2-yl)phosphane; triethylamine In tetrahydrofuran at 60℃; for 6h; Sonogashira Cross-Coupling; Sealed tube;94%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

dimethyl 2-(3,5-dimethoxyphenyl)succinate

dimethyl 2-(3,5-dimethoxyphenyl)succinate

Conditions
ConditionsYield
With 1,3-bis(tert-butyl(pyridin-2-yl)phosphanyl)propane; palladium(II) acetylacetonate; toluene-4-sulfonic acid at 100℃; under 30003 Torr; for 20h; Sealed tube; chemoselective reaction;94%
2-iodobenzyl alcohol
5159-41-1

2-iodobenzyl alcohol

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

[2-(3,5-dimethoxyphenylethynyl)phenyl]methanol
1205555-43-6

[2-(3,5-dimethoxyphenylethynyl)phenyl]methanol

Conditions
ConditionsYield
Stage #1: 2-iodobenzyl alcohol With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 0.0833333h; Sonogashira coupling; Inert atmosphere;
Stage #2: With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20 - 70℃; Sonogashira coupling; Inert atmosphere;
Stage #3: 1-Ethynyl-3,5-dimethoxy-benzene In N,N-dimethyl-formamide at 70℃; for 2.16667h; Sonogashira coupling; Inert atmosphere;
93%
2-bromo-3-thiophenecarboxylic acid-2-pyridyl ester
1382312-69-7

2-bromo-3-thiophenecarboxylic acid-2-pyridyl ester

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

C15H11BrO3S
1382312-86-8

C15H11BrO3S

Conditions
ConditionsYield
Stage #1: 1-Ethynyl-3,5-dimethoxy-benzene With ethylmagnesium bromide In tetrahydrofuran at 0 - 20℃; for 0.5h; Inert atmosphere;
Stage #2: 2-bromo-3-thiophenecarboxylic acid-2-pyridyl ester In tetrahydrofuran at 0℃; for 0.5h;
93%
N-(4-azidobenzoyl)-L-homoserine lactone
1421345-74-5

N-(4-azidobenzoyl)-L-homoserine lactone

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

C21H20N4O5
1421345-53-0

C21H20N4O5

Conditions
ConditionsYield
With copper(l) iodide; N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 16h; Inert atmosphere;93%
5-bromo-N-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine
1453211-46-5

5-bromo-N-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

5-[(3,5-dimethoxyphenyl)ethynyl]-N-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine
1453207-54-9

5-[(3,5-dimethoxyphenyl)ethynyl]-N-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 110℃; for 4h; Sonogashira Cross-Coupling;93%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 120℃; for 2.5h; Inert atmosphere;23 mg
1,4-dihydro-9-isopropylidene-6,7-dimethoxy-1,4-methanonaphthalene

1,4-dihydro-9-isopropylidene-6,7-dimethoxy-1,4-methanonaphthalene

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

(1R*,4S*)-2-((3,5-dimethoxyphenyl)ethynyl)-6,7-dimethoxy-9-(propan-2-ylidene)-1,2,3,4-tetrahydro-1,4-methanonaphthalene

(1R*,4S*)-2-((3,5-dimethoxyphenyl)ethynyl)-6,7-dimethoxy-9-(propan-2-ylidene)-1,2,3,4-tetrahydro-1,4-methanonaphthalene

Conditions
ConditionsYield
With bis(1,5-cyclooctadiene)diiridium(I) dichloride; (+)-(R)-[2,3,2',3'-tetrahydro-5,5'-bi(1,4-benzodioxin)-6,6'-diyl]bis(diphenylphosphane) In 1,2-dichloro-ethane at 70℃; for 5h; Inert atmosphere; Schlenk technique; enantioselective reaction;93%
(1-azido-2,5-di-O-acetyl-3-O-benzoyl-6-deoxy-6-diethylphosphono)-β-ribo-(5S)-hexafuranose

(1-azido-2,5-di-O-acetyl-3-O-benzoyl-6-deoxy-6-diethylphosphono)-β-ribo-(5S)-hexafuranose

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

3-O-benzoyl-6-deoxy-2,5-O-diacetyl-6-diethylphosphono-1-(4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl)-β-D-allofuranose

3-O-benzoyl-6-deoxy-2,5-O-diacetyl-6-diethylphosphono-1-(4-(3,5-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl)-β-D-allofuranose

Conditions
ConditionsYield
With copper(l) iodide; N-ethyl-N,N-diisopropylamine In tetrahydrofuran Huisgen Cycloaddition; Reflux; regioselective reaction;93%
1-bromo-N,N'-bis(2,4-dimethylpent-3-yl)perylene-3,4:9,10-tetracarboxylic diimide
946489-25-4

1-bromo-N,N'-bis(2,4-dimethylpent-3-yl)perylene-3,4:9,10-tetracarboxylic diimide

1-Ethynyl-3,5-dimethoxy-benzene
171290-52-1

1-Ethynyl-3,5-dimethoxy-benzene

C48H46N2O6
1621187-01-6

C48H46N2O6

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine In tetrahydrofuran at 70 - 80℃; Schlenk technique; Inert atmosphere;92%

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