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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3,5-Dimethoxyaniline supplier in China

Cas:10272-07-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hubei Vanz Pharm Co.,Ltd

1 high purity 2 able to provide COA/HNMR/HPLC 3 High quality 4 low price 5 Best service Appearance:white powder Storage:Refrigerator, Under Inert Atmosphere Package:bag/bottle/drum Application:pharmaceutical intermediate Transportation:common

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3,5-DiMethoxyaniline

Cas:10272-07-8

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Aminoresorcinol dimethyl ether

Cas:10272-07-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1000 Gram

FOB Price: $500.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

3,5-Dimethoxyaniline Basic information Product Name: 3,5-Dimethoxyaniline Synonyms: BENZENAMINE, 3,5-DIMETHOXY-;3,5-DIMETHOXYANILINE;3,5-DIMETHOXYPHENYLAMINE;5-AMINORESORCINOL DIMETHYL E

10272-07-8

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

3, 5-Dimethoxyaniline CAS 10272-07-8

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 10272-07-8 with best quality

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 3,5-Dimethoxyaniline Synonyms: BENZENAMINE, 3,5-DIMETHOXY-;3,5-DIMETHOXYANILINE;3,5-DIMETHOXYPHENYLAMINE;5-AMINORESORCINOL DIMETHYL ESTER;5-AMINORESORCINOL DIMETHYL ETHER;AKOS 91392;3,5-di

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White crystal or Colorless liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3,5-Dimethoxyaniline 10272-07-8

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3,5-Dimethoxyaniline CAS:10272-07-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

3,5-Dimethoxyaniline CAS:10272-07-8

Cas:10272-07-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

3,5-Dimethoxyaniline CAS NO.10272-07-8

Cas:10272-07-8

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

3,5-Dimethoxyaniline CAS 10272-07-8

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Specif

3,5-Dimethoxyaniline CAS NO.10272-07-8

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $75.0 / 150.0

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High Purity 3,5-Dimethoxyaniline Cas No.:10272-07-8

Cas:10272-07-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:0

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white to beige-brownish powder or needles Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutica

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

3,5-Dimethoxyaniline

Cas:10272-07-8

Min.Order:1 Kilogram

FOB Price: $95.0 / 100.0

Type:Trading Company

inquiry

Synthetic route

1-azido-3,5-dimethoxybenzene
85862-68-6

1-azido-3,5-dimethoxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With sodium tetrahydroborate; palladium In water for 1.5h; Inert atmosphere;99%
With sodium sulfide; water for 0.5h; Reflux;96%
With ammonium hydroxide at 90℃; for 0.5h;90%
With triethylamine; tris[tert-butyl]phosphonium tetrafluoroborate In tetrahydrofuran; water at 20℃; for 15h; Staudinger Azide Reduction;94 %Spectr.
N-(3,5-dimethoxyphenyl)-2,2,2-trifluoroacetamide
85657-94-9

N-(3,5-dimethoxyphenyl)-2,2,2-trifluoroacetamide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With water; potassium carbonate In methanol for 20h; Ambient temperature;94%
2-Trimethylsilanyl-ethanesulfonic acid (3,5-dimethoxy-phenyl)-amide
106018-88-6

2-Trimethylsilanyl-ethanesulfonic acid (3,5-dimethoxy-phenyl)-amide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With cesium fluoride In N,N-dimethyl-formamide at 95℃; for 40h;93%
1-chloro-3,5-dimethoxybenzene
7051-16-3

1-chloro-3,5-dimethoxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With ammonium hydroxide; potassium phosphate In dimethyl sulfoxide at 80℃; UV-irradiation;93%
With ammonium hydroxide; potassium phosphate; copper(l) iodide; N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide In water; dimethyl sulfoxide at 110℃; for 24h; Inert atmosphere;88%
With ammonium hydroxide; potassium phosphate; copper(l) iodide; N1,N2-bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide In dimethyl sulfoxide at 120℃; for 24h; Inert atmosphere; Schlenk technique;88%
N-(3,5-dimethoxy-phenyl)-acetamide
79257-61-7

N-(3,5-dimethoxy-phenyl)-acetamide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Stage #1: N-(3,5-dimethoxy-phenyl)-acetamide With Schwartz's reagent In tetrahydrofuran at 20℃; for 0.05h; Inert atmosphere;
Stage #2: With water In tetrahydrofuran Inert atmosphere; chemoselective reaction;
86%
With alkaline solution
3,5-dimethoxyphenylboronic acid
192182-54-0

3,5-dimethoxyphenylboronic acid

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With sodium hydroxide; hydroxylamine-O-sulfonic acid In acetonitrile at 20℃; for 16h;82%
1-bromo-3,5-dimethoxybenzene
20469-65-2

1-bromo-3,5-dimethoxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Stage #1: 1-bromo-3,5-dimethoxybenzene With magnesium In tetrahydrofuran Inert atmosphere;
Stage #2: With C10H17NO In tetrahydrofuran; toluene at -78℃; for 2h; Inert atmosphere;
Stage #3: With ammonium chloride In tetrahydrofuran; water; toluene Inert atmosphere;
78%
With ammonium hydroxide; copper(l) iodide; N,N'-bis(3,5-dimethoxyphenyl)cyclopentane-1,1-dicarboxamide; caesium carbonate In dimethyl sulfoxide at 90℃; for 24h; Inert atmosphere; Sealed tube;68%
With ammonia; sodium; ferric nitrate
1-iodo-3,5-dimethoxybenzene
25245-27-6

1-iodo-3,5-dimethoxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With ammonium hydroxide; copper(l) iodide; N,N'-bis(3,5-dimethoxyphenyl)cyclopentane-1,1-dicarboxamide; caesium carbonate In dimethyl sulfoxide at 20℃; for 24h; Inert atmosphere; Sealed tube;75%
3,5-dimethoxyphenol
500-99-2

3,5-dimethoxyphenol

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Stage #1: 3,5-dimethoxyphenol With Nonafluorobutanesulfonyl fluoride; tris(trimethylsilyl)amine; potassium hexamethylsilazane In tetrahydrofuran at 60℃; for 5h; Schlenk technique; Inert atmosphere;
Stage #2: With hydrogenchloride In water at 20℃; for 0.0833333h; pH=3 - 4; Reagent/catalyst; Solvent;
75%
3,5-dimethoxybenzoic acid
1132-21-4

3,5-dimethoxybenzoic acid

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Stage #1: 3,5-dimethoxybenzoic acid With diphenylphosphoranyl azide; triethylamine In toluene at 80℃;
Stage #2: With sodium hydroxide In tetrahydrofuran; toluene at 20℃; for 2h;
43%
Stage #1: 3,5-dimethoxybenzoic acid With diphenylphosphoranyl azide; triethylamine In toluene at 80℃;
Stage #2: With sodium hydroxide In tetrahydrofuran for 2h;
43%
N-hydroxy-3,5-dimethoxybenzamide
710311-79-8

N-hydroxy-3,5-dimethoxybenzamide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Stage #1: N-hydroxy-3,5-dimethoxybenzamide With acetic anhydride; potassium carbonate In dimethyl sulfoxide at 50℃; for 2h; Lossen Rearrangement;
Stage #2: With hydrogenchloride In water; dimethyl sulfoxide at 0℃;
3%
Stage #1: N-hydroxy-3,5-dimethoxybenzamide With potassium carbonate In dimethyl sulfoxide at 90℃; for 3h; Lossen Rearrangement;
Stage #2: With hydrogenchloride In water; dimethyl sulfoxide at 20℃; for 0.0833333h;
1-Bromo-2,4-dimethoxybenzene
17715-69-4

1-Bromo-2,4-dimethoxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With ammonia; sodium amide in fluessiges NH3;
1,3-dimethoxy-5-nitrobenzene
16147-07-2

1,3-dimethoxy-5-nitrobenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With hydrogenchloride; tin
With hydrogenchloride; tin; tin(ll) chloride at 40℃; Reagens 5: Essigsaeure;
With ethanol; nickel Hydrogenation;
With hydrogen; palladium on activated charcoal In ethyl acetate
3,5-dimethoxybenzamide
17213-58-0

3,5-dimethoxybenzamide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With sodium hypobromide at -15℃;
Yield given;
With sodium hypochlorite; sodium hydroxide at 80℃; for 5h;4.1 g
ethyl 3,5-dimethoxybenzoate
17275-82-0

ethyl 3,5-dimethoxybenzoate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 78 percent / hydrazine hydrate / 2 h / Heating
2: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C
3: 93 percent / toluene / 2.5 h / Heating
4: 8.7 g / sodium hydroxide (20percent) / 60 °C
View Scheme
3,5-Dihydroxybenzoic acid
99-10-5

3,5-Dihydroxybenzoic acid

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 84 percent / sodium hydroxide / heating
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate / acetone / 55 °C
2.1: triethylamine; diphenylphosphoranyl azide / toluene / 80 °C
2.2: 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate / acetone / 55 °C
2.1: triethylamine; diphenylphosphoranyl azide / toluene / 80 °C
2.2: 2 h
View Scheme
azido(3,5-dimethoxyphenyl)methanone
75996-26-8

azido(3,5-dimethoxyphenyl)methanone

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 93 percent / toluene / 2.5 h / Heating
2: 8.7 g / sodium hydroxide (20percent) / 60 °C
View Scheme
Multi-step reaction with 2 steps
1: CH2Cl2 / 60 h / Heating
2: 94 percent / H2O, K2CO3 / methanol / 20 h / Ambient temperature
View Scheme
3,5-dimethoxy-benzoic acid hydrazide
51707-38-1

3,5-dimethoxy-benzoic acid hydrazide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C
2: 93 percent / toluene / 2.5 h / Heating
3: 8.7 g / sodium hydroxide (20percent) / 60 °C
View Scheme
3,5-dimethoxybenzoyl chloride
17213-57-9

3,5-dimethoxybenzoyl chloride

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

3,5-dimethoxyphenyl isocyanate
54132-76-2

3,5-dimethoxyphenyl isocyanate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 8.7 g / sodium hydroxide (20percent) / 60 °C
View Scheme
With benzoic acid; sodium hydroxide In tetrahydrofuran at 20℃; for 0.5h; Curtius Rearrangement;
3,5-dihydroxyphenylamine
20734-67-2

3,5-dihydroxyphenylamine

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aqueous dioxane
2: aqueous NaOH
3: aq.-ethanolic alkaline solution
View Scheme
N-(3,5-dihydroxyphenyl)acetamide
73164-69-9

N-(3,5-dihydroxyphenyl)acetamide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous NaOH
2: aq.-ethanolic alkaline solution
View Scheme
methyl 3,5-dimethoxybenzoate
2150-37-0

methyl 3,5-dimethoxybenzoate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: liquid ammonia
2: aqueous sodium hypobromite / -15 °C
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide / 1,4-dioxane / 5 h / 20 °C
2: triethylamine; diphenyl phosphoryl azide / 80 °C
3: sodium hydroxide; benzoic acid / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
3,5-dimethoxyphenol
500-99-2

3,5-dimethoxyphenol

ammonium chloride (NH4Cl)

ammonium chloride (NH4Cl)

2,3-dimethoxyphenol
5150-42-5

2,3-dimethoxyphenol

diethylazodicarboxylate
1972-28-7

diethylazodicarboxylate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With triphenylphosphine In tetrahydrofuran
1-carbomethoxy-3,5-dihydroxybenzene
2150-44-9

1-carbomethoxy-3,5-dihydroxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium carbonate / acetonitrile / 20 °C
2: sodium hydroxide / 1,4-dioxane / 5 h / 20 °C
3: triethylamine; diphenyl phosphoryl azide / 80 °C
4: sodium hydroxide; benzoic acid / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
1-chloro-3,5-dimethoxybenzene
7051-16-3

1-chloro-3,5-dimethoxybenzene

A

bis(3,5-dimethoxyphenyl)amine
1445972-42-8

bis(3,5-dimethoxyphenyl)amine

B

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate In 1,4-dioxane at 50℃; for 24h; Inert atmosphere; Overall yield = 81 %;
C15H23NO3

C15H23NO3

A

heptanamide
628-62-6

heptanamide

B

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Conditions
ConditionsYield
With phosphoric acid; ammonia In ethylene glycol at 145℃; for 5h;A 95 %Spectr.
B 84 %Spectr.
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

(3,5-dimethoxyphenyl)-carbamic acid tert-butyl ester
384793-29-7

(3,5-dimethoxyphenyl)-carbamic acid tert-butyl ester

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; Inert atmosphere;100%
Stage #1: 3.5-dimethoxyaniline With triethylamine In dichloromethane at 20℃;
Stage #2: di-tert-butyl dicarbonate In dichloromethane at 20℃;
99%
at 90℃; for 3h;98%
methyl chloroformate
79-22-1

methyl chloroformate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

methyl N-(3,5-dimethoxyphenyl)carbamate
83015-12-7

methyl N-(3,5-dimethoxyphenyl)carbamate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;100%
With pyridine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;94%
In toluene for 2h; Acylation; Heating;81%
4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline
190728-25-7

4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline

bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

sodium hydrogencarbonate
144-55-8

sodium hydrogencarbonate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-(3,5-Dimethoxyphenyl)-N'-{4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl}urea

N-(3,5-Dimethoxyphenyl)-N'-{4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl}urea

Conditions
ConditionsYield
With triethylamine In toluene100%
3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

Methacryloyl chloride
920-46-7

Methacryloyl chloride

N-(3,5-dimethoxyphenyl)-2-methylacrylamide
134354-28-2

N-(3,5-dimethoxyphenyl)-2-methylacrylamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃;100%
In dichloromethane at 0 - 20℃;
In dichloromethane at 0 - 20℃;
In dichloromethane at 0 - 20℃;
With dmap; triethylamine In dichloromethane at 0 - 20℃;
2-Bromoacetyl bromide
598-21-0

2-Bromoacetyl bromide

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

2-bromo-N-(3,5-dimethoxyphenyl)acetamide

2-bromo-N-(3,5-dimethoxyphenyl)acetamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; for 1.25h; Inert atmosphere;100%
at -77℃;
4-(prop-2-yn-1-ylcarbamoyl)benzoic acid

4-(prop-2-yn-1-ylcarbamoyl)benzoic acid

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

4-(3,5-dimethoxyphenylaminocarbonyl)-N-(prop-2-yn-1-yl)benzamide

4-(3,5-dimethoxyphenylaminocarbonyl)-N-(prop-2-yn-1-yl)benzamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In tetrahydrofuran at 20℃; Inert atmosphere;99.9%
1,1,1-trifluoro-4-phenylbut-3-yn-2-one
58518-08-4

1,1,1-trifluoro-4-phenylbut-3-yn-2-one

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

(Z)-4-(3,5-Dimethoxy-phenylamino)-1,1,1-trifluoro-4-phenyl-but-3-en-2-one
129633-19-8

(Z)-4-(3,5-Dimethoxy-phenylamino)-1,1,1-trifluoro-4-phenyl-but-3-en-2-one

Conditions
ConditionsYield
In methanol Ambient temperature;99%
2-bromo-4'-fluoroacetophenone
403-29-2

2-bromo-4'-fluoroacetophenone

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

2-[(3,5-dimethoxyphenyl)amino]-1-(4-fluorophenyl)ethanone
161139-70-4

2-[(3,5-dimethoxyphenyl)amino]-1-(4-fluorophenyl)ethanone

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In neat (no solvent) at 20℃; for 2h;99%
With sodium hydrogencarbonate In ethanol for 4h; Heating;
(Z)-ethyl 3-(methylamino)-3-phenylacrylate
81051-55-0, 53256-20-5

(Z)-ethyl 3-(methylamino)-3-phenylacrylate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

(Z)-3-(3,5-Dimethoxy-phenylamino)-3-phenyl-acrylic acid ethyl ester

(Z)-3-(3,5-Dimethoxy-phenylamino)-3-phenyl-acrylic acid ethyl ester

Conditions
ConditionsYield
With pyridinium p-toluenesulfonate In dichloromethane for 30h; Heating;99%
2-formylphenyl triflate
84761-77-3

2-formylphenyl triflate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

1,3-dimethoxyacridine
111043-16-4

1,3-dimethoxyacridine

Conditions
ConditionsYield
With palladium diacetate; potassium carbonate; XPhos In toluene at 105℃; for 13h; Mechanism; Reagent/catalyst; Solvent; Temperature; Schlenk technique; Inert atmosphere;99%
acetone
67-64-1

acetone

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-isopropyl-3,5-dimethoxyaniline
108103-33-9

N-isopropyl-3,5-dimethoxyaniline

Conditions
ConditionsYield
With acetic acid; zinc at 20 - 60℃; for 2.5h;99%
2-bromo-5-chlorobenzaldehyde
174265-12-4

2-bromo-5-chlorobenzaldehyde

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

7-chloro-1,3-dimethoxyacridine

7-chloro-1,3-dimethoxyacridine

Conditions
ConditionsYield
Stage #1: 3.5-dimethoxyaniline With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate In toluene at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: 2-bromo-5-chlorobenzaldehyde In toluene at 80℃; for 12h; Inert atmosphere;
99%
2-bromo-5-nitrobenzaldehyde
84459-32-5

2-bromo-5-nitrobenzaldehyde

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

1,3-dimethoxy-7-nitroacridine

1,3-dimethoxy-7-nitroacridine

Conditions
ConditionsYield
Stage #1: 3.5-dimethoxyaniline With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate In toluene at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: 2-bromo-5-nitrobenzaldehyde In toluene at 80℃; for 12h; Inert atmosphere;
99%
2-bromo-6-fluorobenzaldehyde
360575-28-6

2-bromo-6-fluorobenzaldehyde

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

8-fluoro-1,3-dimethoxyacridine

8-fluoro-1,3-dimethoxyacridine

Conditions
ConditionsYield
Stage #1: 3.5-dimethoxyaniline With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate In toluene at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: 2-bromo-6-fluorobenzaldehyde In toluene at 80℃; for 12h; Inert atmosphere;
99%
ortho-bromobenzaldehyde
6630-33-7

ortho-bromobenzaldehyde

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

1,3-dimethoxyacridine
111043-16-4

1,3-dimethoxyacridine

Conditions
ConditionsYield
Stage #1: 3.5-dimethoxyaniline With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate In toluene at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: ortho-bromobenzaldehyde In toluene at 80℃; for 12h; Reagent/catalyst; Solvent; Inert atmosphere;
99%
Stage #1: 3.5-dimethoxyaniline With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate In toluene at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: ortho-bromobenzaldehyde In toluene at 80℃; for 12h; Reagent/catalyst;
99%
1-bromo-3,5-dimethoxybenzene
20469-65-2

1-bromo-3,5-dimethoxybenzene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

tris(3,5-dimethoxyphenyl)amine

tris(3,5-dimethoxyphenyl)amine

Conditions
ConditionsYield
With chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II); sodium t-butanolate In tetrahydrofuran at 70℃; for 24h; Inert atmosphere; Schlenk technique;99%
With chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II); sodium t-butanolate In tetrahydrofuran at 60℃; for 19h; Inert atmosphere;81%
With chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)]palladium (II); sodium t-butanolate In tetrahydrofuran at 60℃; Inert atmosphere;75%
3,5-dimethoxyaniline hydrochloride
40891-33-6

3,5-dimethoxyaniline hydrochloride

4,4'-dimethoxybenzoin
119-52-8

4,4'-dimethoxybenzoin

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

4,6-dimethoxy-2,3-di(4-methoxyphenyl)indole

4,6-dimethoxy-2,3-di(4-methoxyphenyl)indole

Conditions
ConditionsYield
at 130 - 140℃; for 1h;99%
ethyl 6-iodo-4-oxo-3,4-dihydroquinazoline-2-carboxylate
869294-86-0

ethyl 6-iodo-4-oxo-3,4-dihydroquinazoline-2-carboxylate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-(3,5-dimethoxyphenyl)-4-oxo-6-iodo-3,4-dihydroquinazoline-2-carboxamide

N-(3,5-dimethoxyphenyl)-4-oxo-6-iodo-3,4-dihydroquinazoline-2-carboxamide

Conditions
ConditionsYield
Stage #1: 3.5-dimethoxyaniline With trimethylaluminum In n-heptane; 1,2-dichloro-ethane at 0 - 20℃; for 0.5h;
Stage #2: ethyl 6-iodo-4-oxo-3,4-dihydroquinazoline-2-carboxylate In n-heptane; 1,2-dichloro-ethane for 2h; Reflux;
99%
7-nitro-4-chloro-1H-indole-2-carboxylic acid ethyl ester

7-nitro-4-chloro-1H-indole-2-carboxylic acid ethyl ester

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

4-((3,5-dimethoxyphenyl)amino)-7-nitro-1H-indole-2-carboxylic acid ethyl ester

4-((3,5-dimethoxyphenyl)amino)-7-nitro-1H-indole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); sodium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In water; toluene for 4h; Reflux; Inert atmosphere;99%
1-chloro-6-methyl-5-nitroisoquinoline
943606-84-6

1-chloro-6-methyl-5-nitroisoquinoline

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

C18H17N3O4

C18H17N3O4

Conditions
ConditionsYield
With trifluoroacetic acid In isopropyl alcohol at 20 - 90℃; for 16h; Inert atmosphere;98.4%
acetic anhydride
108-24-7

acetic anhydride

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-(3,5-dimethoxy-phenyl)-acetamide
79257-61-7

N-(3,5-dimethoxy-phenyl)-acetamide

Conditions
ConditionsYield
With pyridine at 0 - 20℃;98%
In toluene at 20℃; for 15h; Time; Inert atmosphere;98%
In toluene at 25℃; for 20h;97%
indan-1,2,3-trione hydrate
485-47-2

indan-1,2,3-trione hydrate

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

5,5a,10,10a-Tetrahydro-5a,10a-dihydroxy-4-(2-hydroxy-1,3-dioxoindanyl)-1,3-dimethoxyindeno<1,2-b>indol-10-one

5,5a,10,10a-Tetrahydro-5a,10a-dihydroxy-4-(2-hydroxy-1,3-dioxoindanyl)-1,3-dimethoxyindeno<1,2-b>indol-10-one

Conditions
ConditionsYield
In acetic acid for 16h; Ambient temperature;98%
allyl alcohol
107-18-6

allyl alcohol

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-allyl-3,5-dimethoxyaniline

N-allyl-3,5-dimethoxyaniline

Conditions
ConditionsYield
With titanium(IV) isopropylate; MS 4 Angstroem; palladium diacetate; triphenylphosphine In benzene at 80℃; for 3h; Alkylation; N-allylation;98%
para-bromotoluene
106-38-7

para-bromotoluene

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-(4-tolyl)-3,5-dimethoxyaniline
255835-89-3

N-(4-tolyl)-3,5-dimethoxyaniline

Conditions
ConditionsYield
With C60H86O4P2Pd2(2+)*2BF4(1-); sodium t-butanolate In 1,4-dioxane at 80℃; for 1h;98%
With sodium t-butanolate; 1,1'-bis(diphenylphosphino)ferrocene; tris(dibenzylideneacetone)palladium In toluene at 90℃; for 5h;
3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

N-(3,5-dimethoxyphenyl)-2,2,2-trifluoroacetamide
85657-94-9

N-(3,5-dimethoxyphenyl)-2,2,2-trifluoroacetamide

Conditions
ConditionsYield
With triethylamine In dichloromethane for 1h;98%
With triethylamine In dichloromethane at 0 - 20℃; for 2.5h;98%
With triethylamine In toluene at 15 - 20℃; for 1.5h; Temperature; Solvent;85.4%
With triethylamine In toluene at 18 - 25℃; for 2h;
With triethylamine In dichloromethane at 20℃; for 2.5h; Cooling with ice;
ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

N-(3,5-dimethoxyphenyl)-2,2,2-trifluoroacetamide
85657-94-9

N-(3,5-dimethoxyphenyl)-2,2,2-trifluoroacetamide

Conditions
ConditionsYield
With dmap In tetrahydrofuran for 48h; Heating / reflux;98%
With dmap In tetrahydrofuran for 48h; Reflux;98%

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