Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
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inquiryHigh quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use
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inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
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inquiryR & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou
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inquiry1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
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inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
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inquiryWe are committed to providing our customers with the best products and services at the most competitive prices.Appearance:off-white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as prima
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inquirySupply top quality products with a reasonable price Application:api
3-(4-TRIFLUOROMETHYL-PHENYL)-PROPAN-1-OLAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
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inquirybulk?production Application:Pharmaceutical intermediates
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inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
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inquiryHENAN SUNLAKE ENTERPRISE CORPORATION Our company advantages: 1、The highest quality with the competitive price. 2、Professional human services. 3、The fastest and safest delivery service. 4、The faster and safest delivery service. 5、The hig
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inquiryPrice, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right
Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific L
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Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryUnited Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat
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inquiryR & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou
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inquiry3-(4-TRIFLUOROMETHYL-PHENYL)-PROPAN-1-OLAppearance:yellow to white solid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier li
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inquiryThe company have effective management team, professional technical R & D personnel, the service spirit of customer oriented. We have long-term cooperation with famous domestic manufacturer, and excellent customer resources overseas. We are skilled in
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inquiry3-(4-(trifluoromethyl)phenyl)propan-1-ol 180635-74-9 98%+ Storage:dry and ventilated place Package:suitable for shipping Application:3-(4-(trifluoromethyl)phenyl)propan-1-ol 180635-74-9 98%+ Transportation:air shipping Port:shanghai
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inquiryKnown for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar
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Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en
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inquiryHigh purity Application:Pharmaceutical intermediates, Material synthesis and analyzing the expectant ingredients
3-(4-trifluoromethylphenyl)propionic acid
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Stage #1: 3-(4-trifluoromethylphenyl)propionic acid With borane-THF In tetrahydrofuran at 0 - 20℃; for 15.3h; Stage #2: With methanol In tetrahydrofuran at 0℃; | 100% |
With borane-THF In tetrahydrofuran at 0 - 20℃; for 16h; Inert atmosphere; | 100% |
With sodium tetrahydroborate; iodine In tetrahydrofuran at 70℃; for 16h; Cooling with ice; | 100% |
3-(4-tert-butylphenyl)propionic acid
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With sodium tetrahydroborate; iodine In tetrahydrofuran at 20 - 70℃; for 16.5h; Cooling with ice; | 100% |
4-Iodobenzotrifluoride
allyl alcohol
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); tetramethylammonium formiate; triphenylphosphine In water; N,N-dimethyl-formamide at 80℃; for 4h; Heck Reaction; regioselective reaction; | 67% |
4-(trifluoromethyl)benzylic alcohol
ethanol
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; potassium tert-butylate In tetrahydrofuran at 100℃; for 24h; Inert atmosphere; | 37% |
methyl 3-(4-(trifluoromethyl)phenyl)propanoate
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran for 3h; Heating; | |
With lithium aluminium tetrahydride In diethyl ether at 0℃; | |
With sodium tetrahydroborate In tetrahydrofuran; methanol Reflux; |
4-Trifluoromethylbenzaldehyde
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: tetrahydrofuran / Heating 2: H2 / 10 percent Pd/C / tetrahydrofuran / 2068.59 Torr 3: LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme |
methyl (2E)-3-(4-(trifluoromethyl)phenyl)prop-2-enoate
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2 / 10 percent Pd/C / tetrahydrofuran / 2068.59 Torr 2: LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme |
4-Iodobenzotrifluoride
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: palladium diacetate; lithium chloride; tetrabutylammomium bromide; lithium acetate dihydrate / N,N-dimethyl-formamide / 48 h / 20 °C 2: sodium tetrahydroborate / methanol / 0.17 h / 20 °C View Scheme |
3-(4-trifluoromethylphenyl)propanal
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With sodium tetrahydroborate In methanol at 20℃; for 0.166667h; | 253 mg |
3-(4-trifluoromethylphenyl)prop-2-yn-1-ol
A
(Z)-3-(4-(trifluoromethyl)phenyl)-2-propene-1-ol
B
3-(4-trifluoromethylphenyl)-2-propen-1-ol
C
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With sodium tetrahydroborate; hydrogen; cobalt(II) diacetate tetrahydrate; ethylenediamine In tetrahydrofuran; ethanol; water at 20℃; under 2250.23 Torr; for 12h; Autoclave; Glovebox; diastereoselective reaction; | A n/a B n/a C n/a |
4-Iodobenzotrifluoride
A
(Z)-3-(4-(trifluoromethyl)phenyl)-2-propene-1-ol
B
3-(4-trifluoromethylphenyl)-2-propen-1-ol
C
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / acetonitrile / 12 h / 20 °C / Inert atmosphere; Schlenk technique 2: ethylenediamine; sodium tetrahydroborate; hydrogen; cobalt(II) diacetate tetrahydrate / tetrahydrofuran; water; ethanol / 12 h / 20 °C / 2250.23 Torr / Autoclave; Glovebox View Scheme |
methyl (2E)-3-(4-(trifluoromethyl)phenyl)prop-2-enoate
A
3-(4-trifluoromethylphenyl)-2-propen-1-ol
B
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With [Ru(2-(methylthio)-N-[(pyridin-2-yl)methyl]ethan-1-amine)(triphenylphosphine)Cl2]; potassium tert-butylate; hydrogen In toluene at 40℃; under 22502.3 Torr; for 4h; Overall yield = 63 %; Overall yield = 1.27 g; |
4-trifluoromethylphenylacetylene
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: copper(l) chloride; bathophenanthroline / dimethyl sulfoxide / 12 h / 20 °C / 11251.1 Torr / Inert atmosphere; Autoclave 2: hydrogen / methanol / 18 h / 20 °C / 7500.75 Torr / Autoclave 3: hydrogen; molybdenum hexacarbonyl / 1-methyl-pyrrolidin-2-one / 14 h / 180 °C / 52505.3 Torr / Autoclave View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogen / methanol / 18 h / 20 °C / 7500.75 Torr / Autoclave 2: hydrogen; molybdenum hexacarbonyl / 1-methyl-pyrrolidin-2-one / 14 h / 180 °C / 52505.3 Torr / Autoclave View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With hydrogen; molybdenum hexacarbonyl In 1-methyl-pyrrolidin-2-one at 180℃; under 52505.3 Torr; for 14h; Autoclave; | 280 mg |
trifluoromethylsulfonic anhydride
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With 2,4-lutidine In dichloromethane at -78℃; for 0.5h; Inert atmosphere; | 95% |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
(2E)-3-(4-trifluoromethylphenyl)prop-2-enal
Conditions | Yield |
---|---|
With (S)-diphenylprolinol; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide; acetonitrile at 20℃; for 6h; stereoselective reaction; | 92% |
[bromo(difluoro)methyl](trimethyl)silane
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With potassium hydrogenfluoride In water at 20℃; for 12h; | 90% |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
3-(4-trifluoromethylphenyl)propanal
Conditions | Yield |
---|---|
With pyridinium chlorochromate In dichloromethane at 0 - 20℃; for 3h; | 86.5% |
Stage #1: 3-(4-(trifluoromethyl)phenyl)propan-1-ol With oxalyl dichloride In dichloromethane at -78℃; for 1h; Stage #2: With triethylamine In dichloromethane at -78℃; for 2.5h; | 79.31% |
With pyridinium chlorochromate In dichloromethane at 20℃; for 4h; |
benzoyl chloride
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0 - 20℃; for 5h; | 86% |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
With 1H-imidazole; iodine; triphenylphosphine In dichloromethane at 0 - 20℃; for 1h; Appel Halogenation; Sealed tube; | 82% |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
3-(4-trifluoromethylphenyl)propan-1-ol sulfamate ester
Conditions | Yield |
---|---|
With formic acid; isocyanate de chlorosulfonyle; triethylamine In dichloromethane at 0 - 25℃; Schlenk technique; Inert atmosphere; | 66% |
With pyridine; formic acid; isocyanate de chlorosulfonyle In dichloromethane | 63% |
1,2-bis(t-butyloxycarbonyl)hydrazine
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Stage #1: 1,2-bis(t-butyloxycarbonyl)hydrazine; 3-(4-(trifluoromethyl)phenyl)propan-1-ol With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; 2,6-dimethylpyridine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; copper(I) bromide In acetonitrile at 20℃; for 72h; Stage #2: In methanol; acetonitrile at 0℃; enantioselective reaction; | 59% |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: CBr4; Ph3P / CH2Cl2 / 24 h / 0 °C 2: ethanol / 24 h / Heating 3: NaOH / ethanol / 2 h / Heating View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: CBr4; Ph3P / CH2Cl2 / 24 h / 0 °C 2: ethanol / 24 h / Heating View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: CBr4; Ph3P / CH2Cl2 / 24 h / 0 °C 2: ethanol / 24 h / Heating 3: NaOH / ethanol / 2 h / Heating 4: DCC; DMAP / CH2Cl2 / 24 h / 20 °C View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Inert atmosphere 2: acetic acid / ethanol / 0.1 h / 130 °C / 10501.1 Torr / microwave irradiation 3: N-ethyl-N,N-diisopropylamine / 3-methyl-2-butyl-ketone / 24 h / 90 °C / Inert atmosphere View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
1-ethyl-3-methyl-4-[2-(4-trifluoromethyl-phenyl)-ethyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Inert atmosphere 2: acetic acid / ethanol / 0.1 h / 130 °C / 10501.1 Torr / microwave irradiation View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium hydrogencarbonate; sodium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / ethyl acetate; water / 1.5 h / 0 °C 2: recombinant norcoclaurine synthase from Coptis japonica, first 29 amino acid residues removed / dimethyl sulfoxide / 0.25 h / 30 °C / pH 7 / Enzymatic reaction View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridinium chlorochromate / dichloromethane / 0.25 h / 0 °C 2: (2R,5S)-2-tert-butyl-3,5-dimethylimidazolidin-4-one trifluoromethanesulfonate; tris(bipyridine)ruthenium(II) dichloride hexahydrate; 2,6-dimethylpyridine / dimethyl sulfoxide / 8 h / 23 °C / Inert atmosphere; Sealed tube; Irradiation View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridinium chlorochromate / dichloromethane / 0.25 h / 0 °C 2: C9H18N2O*CHF3O3S; tris(bipyridine)ruthenium(II) dichloride hexahydrate; 2,6-dimethylpyridine / dimethyl sulfoxide / 8 h / 23 °C / Inert atmosphere; Sealed tube; Irradiation View Scheme |
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: pyridinium chlorochromate / dichloromethane / 0.25 h / 0 °C 2: (2R,5S)-2-tert-butyl-3,5-dimethylimidazolidin-4-one trifluoromethanesulfonate; tris(bipyridine)ruthenium(II) dichloride hexahydrate; 2,6-dimethylpyridine / dimethyl sulfoxide / 8 h / 23 °C / Inert atmosphere; Sealed tube; Irradiation 3: sodium tetrahydroborate / dichloromethane; methanol / 3 h / 0 °C View Scheme |
benzoyl chloride
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine / dichloromethane / 5 h / 0 - 20 °C 2: cobalt(II) acetate; manganese(III) triacetate dihydrate; oxygen; 4,5,6,7-tetrafluoro-2-hydroxy-3-(2,2,2-trifluoroethoxy)-3-trifluoromethylisoindolin-1-one / 2,2,2-trifluoroethanol / 48 h / 60 °C / 760.05 Torr View Scheme |
1,2-bis(t-butyloxycarbonyl)hydrazine
3-(4-(trifluoromethyl)phenyl)propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: copper(I) bromide; 2,6-dimethylpyridine; (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / acetonitrile / 72 h / 20 °C 1.2: 0 °C 2.1: pyridine / dichloromethane View Scheme |
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