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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

R-(-)-Arundic acid

Cas:185517-21-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Arundic acid 185517-21-9

Cas:185517-21-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(R)-2-PROPYLOCTANOIC ACID CAS:185517-21-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi

(R)-2-PROPYLOCTANOIC ACID CAS:185517-21-9

Cas:185517-21-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Arundic acid

Cas:185517-21-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Arundic acid

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(R)-(-)-2-Propyloctanoic acid

Cas:185517-21-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

(R)-2-PROPYLOCTANOICACID

Cas:185517-21-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:1 Kilogram

Negotiable

Type:Other

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Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

Arundic acid

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Arundic acid

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Arundic acid

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Arundic acid

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

DB BIOTECH CO., LTD

best seller Application:API

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

(R)-(-)-2-Propyloctanoic acid

(R)-(-)-2-Propyloctanoic acid

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hebei Muhuang Technology Co., Ltd

best seller Application:API

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NUTROCHEM- MANUFACTURE PLACE

best seller Application:API

(R)-2-PROPYLOCTANOIC ACID

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of

Arundic acid

Cas:185517-21-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Trading Company

inquiry

wuxi leji biology technology co., LTD

we a state-level key high-tech enterprises in Yixing Environmental Science and Technology High-tech Development Zone. The company, China Agricultural University, Chinese Academy of Agricultural Sciences, Institute of Ecological Science Park, Beijing

185517-21-9

Cas:185517-21-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

MENGNA

Molecule structure of Arundic acid (CAS NO.185517-21-9): IUPAC Name: (2R)-2-Propyloctanoic acid Molecular Weight: 186.29118 g/mol Molecular Formula: C11H22O2 Density: 0.908 g/cm3 Boiling Point: 289.3 °C at 760 mmHg Flash Point: 154

(R)-(-)-2-Propyloctanoic acid

Cas:185517-21-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(2S)-2-(2-propenyl)octanoic acid
213914-70-6

(2S)-2-(2-propenyl)octanoic acid

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With hydrogen; platinum on activated charcoal In isopropyl alcohol under 7600 Torr; for 1.5h; Catalytic hydrogenation;99%
With hydrogenchloride; sodium chloride; hydrogen; platinum In hexane; ethyl acetate; isopropyl alcohol
With hydrogen; palladium 10% on activated carbon In methanol; ethyl acetate at 20℃; for 1h;n/a
With platinum on carbon; hydrogen In isopropyl alcohol at 30℃; under 3750.38 Torr; for 3.5h; Autoclave; Large scale;1045 g
(R)-2-propyloctan-1-ol
1333204-12-8

(R)-2-propyloctan-1-ol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Stage #1: (R)-2-propyloctan-1-ol With sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In water; acetonitrile at 35℃; for 7h; pH=6.7; Inert atmosphere; aq. phosphate buffer;
Stage #2: With sodium hydrogencarbonate; sodium sulfite In water; acetonitrile at 0℃; pH=8; Inert atmosphere;
Stage #3: With hydrogenchloride In water pH=2; Inert atmosphere;
98%
With sodium hypochlorite solution; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium chlorite In aq. phosphate buffer; acetonitrile at 35℃; for 7h; Inert atmosphere;98%
With sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In aq. phosphate buffer; acetonitrile at 35℃; for 7h; pH=6.7;95%
With sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In aq. phosphate buffer; water; acetonitrile at 35℃; for 7h; pH=6.7;95%
(2R)-2-propyloctanoic acid dibenzylamine salt

(2R)-2-propyloctanoic acid dibenzylamine salt

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With potassium hydroxide In water at 20℃; for 0.166667h;97.1%
(2S)-2-(2-propynyl)octanoic acid
185463-37-0

(2S)-2-(2-propynyl)octanoic acid

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate at 20℃; for 7305h;97%
With hydrogen; platinum on activated charcoal In isopropyl alcohol under 3800 Torr; for 2.5h; Catalytic hydrogenation;94.6%
With hydrogen; 5%-palladium/activated carbon In monoethylene glycol diethyl ether; water under 3800.26 Torr; for 5h;89%
palladium In methanol; ethyl acetate
With hydrogenchloride; sodium chloride; hydrogen; palladium In 1,2-dimethoxyethane; hexane; ethyl acetate
C11H18O2

C11H18O2

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In methanol under 3040.2 Torr; for 2h;96%
(S)-2-[(E)-1-propenyl]-(Z)-oct-4-enoic acid
1192553-22-2

(S)-2-[(E)-1-propenyl]-(Z)-oct-4-enoic acid

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 3040.2 Torr; for 2h;96%
(1R)-2-endo-[(2R)-propyloctanoyl]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
1087312-90-0

(1R)-2-endo-[(2R)-propyloctanoyl]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol

A

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
464-49-3

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

B

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In water; acetonitrile at 0℃; for 1h;A n/a
B 95%
(2S,3R)-3-propylnonane-1,2-diol

(2S,3R)-3-propylnonane-1,2-diol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With 1‐methyl‐2‐azaadamantane‐N‐oxyl; sodium hypochlorite; sodium chlorite In aq. phosphate buffer; acetone at 20℃; for 3h; pH=6.8;92%
N-(2-hydroxyphenyl)-(2R)-N-[(1S)-1-phenylethyl]-2-propyloctanamide

N-(2-hydroxyphenyl)-(2R)-N-[(1S)-1-phenylethyl]-2-propyloctanamide

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With ferric nitrate In 1,4-dioxane for 20h; Heating;60%
N-[(2S)-2-propyloctanoyl]-(1S)-(-)-10,2-camphorsultam
213914-72-8

N-[(2S)-2-propyloctanoyl]-(1S)-(-)-10,2-camphorsultam

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydroxide; dihydrogen peroxide In 1,2-dimethoxyethane; water at -20℃; for 0.833333h;59%
With tetra(n-butyl)ammonium hydroxide; dihydrogen peroxide In tetrahydrofuran at -20℃; for 0.833333h; Hydrolysis;59.3%
N-(2R-(2-propyl)octanoyl)-(1S)-(-)-2,10-camphorsultam

N-(2R-(2-propyl)octanoyl)-(1S)-(-)-2,10-camphorsultam

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Stage #1: N-(2R-(2-propyl)octanoyl)-(1S)-(-)-2,10-camphorsultam With tetra(n-butyl)ammonium hydroxide; dihydrogen peroxide In tetrahydrofuran; water at -20℃; for 0.833333h;
Stage #2: With sodium sulfite In tetrahydrofuran; water at 20℃; for 0.5h;
59.3%
(1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-O-yl) 2-hexylpent-3-enoate

(1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-O-yl) 2-hexylpent-3-enoate

A

(+)-(S)-2-propyloctanoic acid
807363-10-6

(+)-(S)-2-propyloctanoic acid

B

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Stage #1: (1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-O-yl) 2-hexylpent-3-enoate With hydrogen; platinum(IV) oxide In diethyl ether at 20℃; under 760 Torr; for 12h;
Stage #2: With lithium hydroxide; dihydrogen peroxide In methanol; water for 6h; Title compound not separated from byproducts;
Stage #1: (1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-O-yl) 2-hexylpent-3-enoate With hydrogen; platinum(IV) oxide In diethyl ether at 20℃; under 760 Torr; for 12h;
Stage #2: With titanium(IV) isopropylate; benzyl alcohol In toluene for 7h; Heating;
Stage #3: With hydrogen; palladium on activated charcoal In methanol at 20℃; under 760 Torr; for 6h; Title compound not separated from byproducts;
2-hexyl-N-(2-hydroxyphenyl)-(2S/R)-N-[(1S)-1-phenylethyl]pent-4-enamide

2-hexyl-N-(2-hydroxyphenyl)-(2S/R)-N-[(1S)-1-phenylethyl]pent-4-enamide

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2 / 10 percent Pd/C / methanol / 1 h
2: 60 percent / aq. Fe(NO3)3 / dioxane / 20 h / Heating
View Scheme
N-octanoyl-(1S)-(-)-10,2-camphorsultam
141341-55-1

N-octanoyl-(1S)-(-)-10,2-camphorsultam

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 85.3 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 3.5 h / -78 - -30 °C
2.1: 89.6 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 0.17 h / -10 °C
3.1: 94.6 percent / H2 / Pt/C / propan-2-ol / 2.5 h / 3800 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 71.7 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 6 h / -78 - 0 °C
2.1: 100 percent / H2 / Pd/C / ethyl acetate; methanol / 1 h
3.1: 59.3 percent / aq. H2O2; tetrabutylammonium hydroxide / tetrahydrofuran / 0.83 h / -20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C
1.2: 71.7 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 6 h / -78 - 0 °C
2.1: 82.2 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 2 h / -10 °C
3.1: 99 percent / H2 / Pt/C / propan-2-ol / 1.5 h / 7600 Torr
View Scheme
Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 0.5 h / -60 °C / Large scale
1.2: 4 h / -65 - 5 °C / Large scale
2.1: 2-methyl-but-2-ene; dihydrogen peroxide; tetra(n-butyl)ammonium hydroxide / water; 1,2-dimethoxyethane / -10 - 5 °C
3.1: platinum on carbon; hydrogen / isopropyl alcohol / 3.5 h / 30 °C / 3750.38 Torr / Autoclave; Large scale
View Scheme
Multi-step reaction with 3 steps
1.1: lithium cyclohexylisopropylamide / tetrahydrofuran
1.2: -5 - 5 °C
2.1: 2-methyl-but-2-ene; dihydrogen peroxide; tetra(n-butyl)ammonium hydroxide / water; 1,2-dimethoxyethane / -10 - 5 °C
3.1: platinum on carbon; hydrogen / isopropyl alcohol / 3.5 h / 30 °C / 3750.38 Torr / Autoclave; Large scale
View Scheme
n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

1.2-isopropylidene-glycerol

1.2-isopropylidene-glycerol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98.6 percent / Et3N; 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 0 °C
2.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C
2.2: 85.3 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 3.5 h / -78 - -30 °C
3.1: 89.6 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 0.17 h / -10 °C
4.1: 94.6 percent / H2 / Pt/C / propan-2-ol / 2.5 h / 3800 Torr
View Scheme
Multi-step reaction with 4 steps
1.1: 98.6 percent / Et3N; 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 0 °C
2.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C
2.2: 71.7 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 6 h / -78 - 0 °C
3.1: 100 percent / H2 / Pd/C / ethyl acetate; methanol / 1 h
4.1: 59.3 percent / aq. H2O2; tetrabutylammonium hydroxide / tetrahydrofuran / 0.83 h / -20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: 98.6 percent / Et3N; 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 0 °C
2.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C
2.2: 71.7 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 6 h / -78 - 0 °C
3.1: 82.2 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 2 h / -10 °C
4.1: 99 percent / H2 / Pt/C / propan-2-ol / 1.5 h / 7600 Torr
View Scheme
N-[(2S)-2-hexyl-4-pentynoyl]-(1S)-(-)-10,2-camphorsultam
213914-74-0

N-[(2S)-2-hexyl-4-pentynoyl]-(1S)-(-)-10,2-camphorsultam

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89.6 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 0.17 h / -10 °C
2: 94.6 percent / H2 / Pt/C / propan-2-ol / 2.5 h / 3800 Torr
View Scheme
N-(2S)-(2-hexyl-4-pentenoyl)-(1S)-(-)-10,2-camphorsultam
213914-68-2

N-(2S)-(2-hexyl-4-pentenoyl)-(1S)-(-)-10,2-camphorsultam

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 100 percent / H2 / Pd/C / ethyl acetate; methanol / 1 h
2: 59.3 percent / aq. H2O2; tetrabutylammonium hydroxide / tetrahydrofuran / 0.83 h / -20 °C
View Scheme
Multi-step reaction with 2 steps
1: 82.2 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 2 h / -10 °C
2: 99 percent / H2 / Pt/C / propan-2-ol / 1.5 h / 7600 Torr
View Scheme
Multi-step reaction with 2 steps
1: 2-methyl-but-2-ene; dihydrogen peroxide; tetra(n-butyl)ammonium hydroxide / water; 1,2-dimethoxyethane / -10 - 5 °C
2: platinum on carbon; hydrogen / isopropyl alcohol / 3.5 h / 30 °C / 3750.38 Torr / Autoclave; Large scale
View Scheme
(2R)-2-propyloctanamide
807362-94-3

(2R)-2-propyloctanamide

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With hydrogenchloride; water; acetic acid at 130℃; for 10h;n/a
With methanesulfonic acid In acetic acid at 105 - 112℃; for 13h; Product distribution / selectivity;n/a
With methanesulfonic acid; acetic acid at 40 - 105℃; for 13h;
Reaxys ID: 11368098

Reaxys ID: 11368098

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Stage #1: With potassium hydroxide In water at 20℃; for 0.166667h;
Stage #2: With hydrogenchloride In n-heptane; Isopropyl acetate; water Product distribution / selectivity;
n/a
(R)-2-(benzo-1,3-dithiol-2-yl)octan-1-ol
1333204-09-3

(R)-2-(benzo-1,3-dithiol-2-yl)octan-1-ol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere
1.2: 18 h / 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere
2.2: 0.08 h / Inert atmosphere
3.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere
3.2: Inert atmosphere
4.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer
4.2: 0 °C / pH 8 / Inert atmosphere
4.3: pH 2 / Inert atmosphere
View Scheme
2-((R)-1-(benzyloxy)octan-2-yl)benzo-1,3-dithiole
1333204-10-6

2-((R)-1-(benzyloxy)octan-2-yl)benzo-1,3-dithiole

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere
1.2: 0.08 h / Inert atmosphere
2.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere
2.2: Inert atmosphere
3.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer
3.2: 0 °C / pH 8 / Inert atmosphere
3.3: pH 2 / Inert atmosphere
View Scheme
2-((R)-1-(benzyloxy)octan-2-yl)-2-ethylbenzo-1,3-dithiole
1333204-11-7

2-((R)-1-(benzyloxy)octan-2-yl)-2-ethylbenzo-1,3-dithiole

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere
1.2: Inert atmosphere
2.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer
2.2: 0 °C / pH 8 / Inert atmosphere
2.3: pH 2 / Inert atmosphere
View Scheme
C15H20OS2

C15H20OS2

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere
2.2: 18 h / 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere
3.2: 0.08 h / Inert atmosphere
4.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere
4.2: Inert atmosphere
5.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer
5.2: 0 °C / pH 8 / Inert atmosphere
5.3: pH 2 / Inert atmosphere
View Scheme
Octanal
124-13-0

Octanal

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: (R)-5-benzyl-2,2,3-trimethylimidazolidin-4-one; sodium dihydrogenphosphate; benzoic acid / water; acetonitrile / 24 h / 0 °C / Inert atmosphere
2.1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C / Inert atmosphere
3.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere
3.2: 18 h / 20 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere
4.2: 0.08 h / Inert atmosphere
5.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere
5.2: Inert atmosphere
6.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer
6.2: 0 °C / pH 8 / Inert atmosphere
6.3: pH 2 / Inert atmosphere
View Scheme
(2S,3S,4S)-1-benzyloxy-4-[(E)-1-propenyl]-(Z)-dec-6-ene-2,3-diol
1192553-20-0

(2S,3S,4S)-1-benzyloxy-4-[(E)-1-propenyl]-(Z)-dec-6-ene-2,3-diol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium periodate; sodium hydrogencarbonate / dichloromethane; water / 6 h / 20 °C
2: sodium chlorite; sodium dihydrogen phosphate monohydrate; cyclohexene / water; tert-butyl alcohol / 12 h / 20 °C
3: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C / 3040.2 Torr
View Scheme
C11H18O

C11H18O

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium chlorite; sodium dihydrogen phosphate monohydrate; cyclohexene / water; tert-butyl alcohol / 12 h / 20 °C
2: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C / 3040.2 Torr
View Scheme
C28H37N2O3Pol

C28H37N2O3Pol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Conditions
ConditionsYield
With dihydrogen peroxide; lithium hydroxide In tetrahydrofuran; water at 0 - 20℃;1.65 g
(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

dibenzylamine
103-49-1

dibenzylamine

Reaxys ID: 11368098

Reaxys ID: 11368098

Conditions
ConditionsYield
In 1,2-dimethoxyethane; water at 60℃; for 0.166667 - 0.416667h; Product distribution / selectivity;100%
In isopropyl alcohol; acetonitrile at 60℃; for 0.166667 - 0.416667h; Product distribution / selectivity;85%
In water; acetonitrile at 60℃; for 0.166667 - 0.416667h; Product distribution / selectivity;79%
(R)-1-phenyl-ethyl-amine
3886-69-9

(R)-1-phenyl-ethyl-amine

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

Reaxys ID: 11380179

Reaxys ID: 11380179

Conditions
ConditionsYield
In acetonitrile at 70℃; for 0.25h;40%
(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

(2R)-2-propyloctanoic acid, sodium salt
848899-76-3

(2R)-2-propyloctanoic acid, sodium salt

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 20℃; for 2h;
With sodium hydroxide In water
Stage #1: (R)-(-)-arundic acid With sodium hydroxide In tetrahydrofuran; water at 25 - 50℃; for 24h;
Stage #2: With calcium chloride In tetrahydrofuran; water at 50℃; for 2h; Solvent; Temperature;
α-bromoacetophenone
70-11-1

α-bromoacetophenone

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

2-oxo-2-phenylethyl (R)-2-propyloctanoate

2-oxo-2-phenylethyl (R)-2-propyloctanoate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 5h;n/a
With triethylamine In dichloromethane
With potassium carbonate In acetone at 20℃; for 1h;
(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

lithium (2R)-2-propyloctanoate
888038-78-6

lithium (2R)-2-propyloctanoate

Conditions
ConditionsYield
With lithium hydroxide In ethanol; water for 0.5h;
(2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}-3-(3,4-difluorophenyl)-2-[4-(methylsulfonyl)phenyl]but-2-en-1-ol
885020-48-4

(2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}-3-(3,4-difluorophenyl)-2-[4-(methylsulfonyl)phenyl]but-2-en-1-ol

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

(2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}-3-(3,4-difluorophenyl)-2-[4-(methylsulfonyl)phenyl]but-2-en-1-yl (2R)-2-propyloctanoate
888010-86-4

(2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}-3-(3,4-difluorophenyl)-2-[4-(methylsulfonyl)phenyl]but-2-en-1-yl (2R)-2-propyloctanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 3h;
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

(R)-(-)-arundic acid
185517-21-9

(R)-(-)-arundic acid

(2R)-propyloctanoic acid N-(S)-(-)-α-methylbenzylamide

(2R)-propyloctanoic acid N-(S)-(-)-α-methylbenzylamide

Conditions
ConditionsYield
Stage #1: (R)-(-)-arundic acid With oxalyl dichloride In dichloromethane at 0℃; for 1h;
Stage #2: (S)-1-phenyl-ethylamine With triethylamine In dichloromethane at 0℃; for 1h; Further stages.;

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