Products

Refine

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

PYRIDOMYCIN

Cas:18791-21-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

PYRIDOMYCIN

Cas:18791-21-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Pyridomycin

Cas:18791-21-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

PYRIDOMYCIN

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-Hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridylmethyl)-1,4-dioxa-8-azacyclododeca-6-yl]-2-pyridinecarboxamide

Cas:18791-21-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3-Hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridylmethyl)-1,4-dioxa-8-azacyclododeca-6-yl]-2-pyridinecarboxamide

Cas:18791-21-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

18791-21-4 CAS NO.18791-21-4

Cas:18791-21-4

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

3-Hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridylmethyl)-1,4-dioxa-8-azacyclododeca-6-yl]-2-pyridinecarboxamide

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services：A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

PYRIDOMYCIN

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

PYRIDOMYCIN

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

18791-21-4

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

PYRIDOMYCIN cas 18791-21-4Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

PYRIDOMYCIN cas 18791-21-4

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-Hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridylmethyl)-1,4-dioxa-8-azacyclododeca-6-yl]-2-pyridinecarboxamide

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-Hydroxy-N-[(2Z,5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-(1-methylpropylidene)-3,7,12-trioxo-9-(3-pyridylmethyl)-1,4-dioxa-8-azacyclododeca-6-yl]-2-pyridinecarboxamide

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

18791-21-4 CAS NO.18791-21-4

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NovaChemistry

High purity Application:Screening the references, analyzing the expectant ingredients

Pyridomycin

Cas:18791-21-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry
View More

Synthetic route

3-Benzyloxy-pyridine-2-carboxylic acid {(5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-[1-methyl-prop-(Z)-ylidene]-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl}-amide
128829-10-7

3-Benzyloxy-pyridine-2-carboxylic acid {(5R,6S,9S,10S,11R)-10-hydroxy-5,11-dimethyl-2-[1-methyl-prop-(Z)-ylidene]-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl}-amide

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
With hydrogen; palladium In methanol95%
((S)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol

((S)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 15 steps
1: NaIO4, RuCl3 / CCl4; acetonitrile; H2O / 1 h / Ambient temperature
2: 83 percent / DCC,DMAP / ethyl acetate / 2 h / Ambient temperature
3: aq. TFA / 1 h / Ambient temperature
4: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
5: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
6: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
7: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
8: DCC, HOBt / dimethylformamide / 68 h / 2 °C
9: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
10: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
11: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
12: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
13: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
15: 95 percent / H2 / Pd-black / methanol
View Scheme
(R)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid
128829-04-9

(R)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 14 steps
1: 83 percent / DCC,DMAP / ethyl acetate / 2 h / Ambient temperature
2: aq. TFA / 1 h / Ambient temperature
3: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
4: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
5: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
6: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
7: DCC, HOBt / dimethylformamide / 68 h / 2 °C
8: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
9: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
10: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
11: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
12: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
14: 95 percent / H2 / Pd-black / methanol
View Scheme
(S)-1-Benzyloxy-3-ethyl-pentane-2,3-diol

(S)-1-Benzyloxy-3-ethyl-pentane-2,3-diol

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 17 steps
1: DMP, H2SO4 / 2 h / Ambient temperature
2: H2 / Pd(OH)2 / methanol / 1 h / Ambient temperature
3: NaIO4, RuCl3 / CCl4; acetonitrile; H2O / 1 h / Ambient temperature
4: 83 percent / DCC,DMAP / ethyl acetate / 2 h / Ambient temperature
5: aq. TFA / 1 h / Ambient temperature
6: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
7: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
8: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
9: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
10: DCC, HOBt / dimethylformamide / 68 h / 2 °C
11: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
12: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
13: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
14: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
15: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
17: 95 percent / H2 / Pd-black / methanol
View Scheme
(S)-5-Benzyloxymethyl-4,4-diethyl-2,2-dimethyl-[1,3]dioxolane

(S)-5-Benzyloxymethyl-4,4-diethyl-2,2-dimethyl-[1,3]dioxolane

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 16 steps
1: H2 / Pd(OH)2 / methanol / 1 h / Ambient temperature
2: NaIO4, RuCl3 / CCl4; acetonitrile; H2O / 1 h / Ambient temperature
3: 83 percent / DCC,DMAP / ethyl acetate / 2 h / Ambient temperature
4: aq. TFA / 1 h / Ambient temperature
5: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
6: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
7: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
8: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
9: DCC, HOBt / dimethylformamide / 68 h / 2 °C
10: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
11: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
12: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
13: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
14: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
16: 95 percent / H2 / Pd-black / methanol
View Scheme
(S)-1-Benzyloxy-3-ethyl-2-methoxymethoxy-pentan-3-ol
128829-03-8

(S)-1-Benzyloxy-3-ethyl-2-methoxymethoxy-pentan-3-ol

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 18 steps
1: aq. HCl / dioxane / 3 h / 50 °C
2: DMP, H2SO4 / 2 h / Ambient temperature
3: H2 / Pd(OH)2 / methanol / 1 h / Ambient temperature
4: NaIO4, RuCl3 / CCl4; acetonitrile; H2O / 1 h / Ambient temperature
5: 83 percent / DCC,DMAP / ethyl acetate / 2 h / Ambient temperature
6: aq. TFA / 1 h / Ambient temperature
7: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
8: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
9: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
10: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
11: DCC, HOBt / dimethylformamide / 68 h / 2 °C
12: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
13: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
14: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
15: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
16: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
18: 95 percent / H2 / Pd-black / methanol
View Scheme
(R)-3-Ethyl-2,3-dihydroxy-pentanoic acid (1R,2S)-2-benzyloxycarbonylamino-2-carboxy-1-methyl-ethyl ester

(R)-3-Ethyl-2,3-dihydroxy-pentanoic acid (1R,2S)-2-benzyloxycarbonylamino-2-carboxy-1-methyl-ethyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
2: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
3: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
4: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
5: DCC, HOBt / dimethylformamide / 68 h / 2 °C
6: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
7: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
8: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
9: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
10: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
12: 95 percent / H2 / Pd-black / methanol
View Scheme
(5R,6S,9S,10S,11R)-6-Amino-10-hydroxy-5,11-dimethyl-2-[1-methyl-prop-(Z)-ylidene]-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododecane-3,7,12-trione

(5R,6S,9S,10S,11R)-6-Amino-10-hydroxy-5,11-dimethyl-2-[1-methyl-prop-(Z)-ylidene]-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododecane-3,7,12-trione

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: 95 percent / H2 / Pd-black / methanol
View Scheme
(R)-3-Ethyl-2,3-dihydroxy-pentanoic acid (1R,2S)-2-benzhydryloxycarbonyl-2-benzyloxycarbonylamino-1-methyl-ethyl ester
128849-60-5

(R)-3-Ethyl-2,3-dihydroxy-pentanoic acid (1R,2S)-2-benzhydryloxycarbonyl-2-benzyloxycarbonylamino-1-methyl-ethyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
2: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
3: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
4: DCC, HOBt / dimethylformamide / 68 h / 2 °C
5: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
6: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
7: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
8: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
9: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
11: 95 percent / H2 / Pd-black / methanol
View Scheme
(R)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid (1R,2S)-2-benzhydryloxycarbonyl-2-benzyloxycarbonylamino-1-methyl-ethyl ester
128849-59-2

(R)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid (1R,2S)-2-benzhydryloxycarbonyl-2-benzyloxycarbonylamino-1-methyl-ethyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 13 steps
1: aq. TFA / 1 h / Ambient temperature
2: ethyl acetate; petroleum ether / 2.5 h / Ambient temperature
3: DCC, DMAP / ethyl acetate / 2.5 h / Ambient temperature
4: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
5: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
6: DCC, HOBt / dimethylformamide / 68 h / 2 °C
7: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
8: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
9: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
10: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
11: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
13: 95 percent / H2 / Pd-black / methanol
View Scheme
[(2R,5R,6S,9S,10S,11R)-2-((E)-1-Ethyl-propenyl)-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl]-carbamic acid benzyl ester
128829-06-1

[(2R,5R,6S,9S,10S,11R)-2-((E)-1-Ethyl-propenyl)-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl]-carbamic acid benzyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
2: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
3: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
4: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
6: 95 percent / H2 / Pd-black / methanol
View Scheme
[(2R,5R,6S,9S,10S,11R)-2-(1-Ethyl-1-hydroxy-propyl)-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl]-carbamic acid benzyl ester

[(2R,5R,6S,9S,10S,11R)-2-(1-Ethyl-1-hydroxy-propyl)-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl]-carbamic acid benzyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
2: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
3: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
4: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
5: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
7: 95 percent / H2 / Pd-black / methanol
View Scheme
{(5R,6S,9S,10S,11R)-10-Hydroxy-5,11-dimethyl-2-[1-methyl-prop-(Z)-ylidene]-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl}-carbamic acid benzyl ester
128829-09-4

{(5R,6S,9S,10S,11R)-10-Hydroxy-5,11-dimethyl-2-[1-methyl-prop-(Z)-ylidene]-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl}-carbamic acid benzyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
3: 95 percent / H2 / Pd-black / methanol
View Scheme
(2R,3S,4S)-4-Amino-3-hydroxy-2-methyl-5-pyridin-3-yl-pentanoic acid (R)-1-((1R,2S)-2-benzyloxycarbonylamino-2-carboxy-1-methyl-ethoxycarbonyl)-2-ethyl-2-hydroxy-butyl ester

(2R,3S,4S)-4-Amino-3-hydroxy-2-methyl-5-pyridin-3-yl-pentanoic acid (R)-1-((1R,2S)-2-benzyloxycarbonylamino-2-carboxy-1-methyl-ethoxycarbonyl)-2-ethyl-2-hydroxy-butyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: DCC, HOBt / dimethylformamide / 68 h / 2 °C
2: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
3: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
4: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
5: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
6: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
8: 95 percent / H2 / Pd-black / methanol
View Scheme
((5R,6S,9S,10S,11R)-10-Hydroxy-5,11-dimethyl-3,7,12-trioxo-2-propionyl-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl)-carbamic acid benzyl ester
128829-07-2, 128829-11-8

((5R,6S,9S,10S,11R)-10-Hydroxy-5,11-dimethyl-3,7,12-trioxo-2-propionyl-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl)-carbamic acid benzyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
2: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
3: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
5: 95 percent / H2 / Pd-black / methanol
View Scheme
(2R,3S,4S)-4-Azido-3-hydroxy-2-methyl-5-pyridin-3-yl-pentanoic acid (R)-1-((1R,2S)-2-benzyloxycarbonylamino-2-carboxy-1-methyl-ethoxycarbonyl)-2-ethyl-2-hydroxy-butyl ester

(2R,3S,4S)-4-Azido-3-hydroxy-2-methyl-5-pyridin-3-yl-pentanoic acid (R)-1-((1R,2S)-2-benzyloxycarbonylamino-2-carboxy-1-methyl-ethoxycarbonyl)-2-ethyl-2-hydroxy-butyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
2: DCC, HOBt / dimethylformamide / 68 h / 2 °C
3: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
4: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
5: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
6: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
7: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
9: 95 percent / H2 / Pd-black / methanol
View Scheme
{(5R,6S,9S,10S,11R)-2-[1-(Diethoxy-phosphoryloxy)-prop-(E)-ylidene]-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl}-carbamic acid benzyl ester

{(5R,6S,9S,10S,11R)-2-[1-(Diethoxy-phosphoryloxy)-prop-(E)-ylidene]-10-hydroxy-5,11-dimethyl-3,7,12-trioxo-9-pyridin-3-ylmethyl-1,4-dioxa-8-aza-cyclododec-6-yl}-carbamic acid benzyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
2: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
4: 95 percent / H2 / Pd-black / methanol
View Scheme
(2R,3S,4S)-4-Azido-3-formyloxy-2-methyl-5-pyridin-3-yl-pentanoic acid (R)-1-((1R,2S)-2-benzhydryloxycarbonyl-2-benzyloxycarbonylamino-1-methyl-ethoxycarbonyl)-2-ethyl-2-hydroxy-butyl ester

(2R,3S,4S)-4-Azido-3-formyloxy-2-methyl-5-pyridin-3-yl-pentanoic acid (R)-1-((1R,2S)-2-benzhydryloxycarbonyl-2-benzyloxycarbonylamino-1-methyl-ethoxycarbonyl)-2-ethyl-2-hydroxy-butyl ester

pyridomicin
18791-21-4

pyridomicin

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 1.) aq. HCl 2.) aq. TFA / 1 ) dioxane, 35 deg C, 12 h 2 ) rt., 20 min.
2: H2 / Raney-Ni W-4 / methanol / 0.67 h / 35 °C
3: DCC, HOBt / dimethylformamide / 68 h / 2 °C
4: 95 percent / SOCl2 / pyridine / 1 h / -30 °C
5: 84 percent / O3/O2 / CH2Cl2 / 0 h / -78 °C
6: 1)NaH / 1)THF, 0 deg C, 15 min., 2)0 deg C, 1 h
7: 25 percent / tetrahydrofuran / 3 h / -70 - -30 °C
8: H2 / Pd-black / methanol / 0.5 h / Ambient temperature
10: 95 percent / H2 / Pd-black / methanol
View Scheme

Related products

1879-16-9

Benzene,1-methoxy-4-(methylthio)-
18791-75-8

2-Thiophenecarboxaldehyde,4-bromo-
18791-78-1

3-Thiophenecarboxaldehyde,4-bromo-
18791-99-6

2-Thiophenecarbonitrile,4-bromo-
18793-46-9

Acetamide, N-(1-methyl-2-phenylethenyl)-, (E)- (9CI)
18793-47-0

Acetamide, N-(1-methyl-2-phenylethenyl)-, (Z)- (9CI)
187947-37-1

5,8,11,14-Eicosatetraenamide,N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-, (5Z,8Z,11Z,14Z)-
18794-77-9

Thiophene, 2-hexyl-
18794-84-8

1,6,10-Dodecatriene,7,11-dimethyl-3-methylene-, (6E)-
187949-02-6

4(3H)-Quinazolinone,7-chloro-3-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View