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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Benzocyclobutene-4-Boronic Acid supplier in China

Cas:195730-31-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Factory supply Benzocyclobutene-4-boronic acid CAS 195730-31-5 with fast delivery Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediate

Factory supply Benzocyclobutene-4-boronic acid CAS 195730-31-5 with fast delivery

Cas:195730-31-5

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of chemicals. After many years of efforts, we have established stable

4-bicyclo[4.2.0]octa-1(6),2,4,7-tetraenylboronic Acid

Cas:195730-31-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

BICYCLO[4.2.0]OCTA-1,3,5,7-TETRAEN-3-YLBORONIC ACID

Cas:195730-31-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

Benzocyclobutene-4-boronic acid CAS 195730-31-5

Cas:195730-31-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 195730-31-5 with competitive price

Cas:195730-31-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Boronic acid,bicyclo[4.2.0]octa-1,3,5-trien-3-yl- (9CI) 195730-31-5

Cas:195730-31-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Benzocyclobutene-4-boronic acid CAS:195730-31-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

Benzocyclobutene-4-boronic acid CAS:195730-31-5

Cas:195730-31-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Boronic acid,bicyclo[4.2.0]octa-1,3,5-trien-3-yl- (9CI)

Cas:195730-31-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Boronic acid,bicyclo[4.2.0]octa-1,3,5-trien-3-yl- (9CI)

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Benzocyclobutene-4-Boronic Acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

4-BBCB

Cas:195730-31-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-BBCB

Cas:195730-31-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Boronic acid,bicyclo[4.2.0]octa-1,3,5-trien-3-yl- (9CI)

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Benzocyclobutene-4-Boronic Acid

Cas:195730-31-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

195730-31-5 Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

195730-31-5 Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

195730-31-5 Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

195730-31-5 Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

BENZOCYCLOBUTENE-4-BORONIC ACID

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-BBCB

Cas:195730-31-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Benzocyclobutene-4-Boronic Acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Boronic acid,bicyclo[4.2.0]octa-1,3,5-trien-3-yl- (9CI)

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Benzocyclobutene-4-Boronic Acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Benzocyclobutene-4-boronic acid

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Boronic acid,bicyclo[4.2.0]octa-1,3,5-trien-3-yl- (9CI)

Cas:195730-31-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

4-bromobenzocyclobutene
1073-39-8

4-bromobenzocyclobutene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

Conditions
ConditionsYield
Stage #1: 4-bromobenzocyclobutene With magnesium In tetrahydrofuran
Stage #2: With Trimethyl borate In tetrahydrofuran at -78 - 20℃;
73%
1,3-dibromobenzene
108-36-1

1,3-dibromobenzene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

1,3-bis(benzocyclobuten-4-yl)benzene

1,3-bis(benzocyclobuten-4-yl)benzene

Conditions
ConditionsYield
With borax; tetrabutylammomium bromide; palladium dichloride In ethanol at 20℃; for 3h; Suzuki coupling;98%
1.4-dibromobenzene
106-37-6

1.4-dibromobenzene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

1,4-bis(benzocyclobuten-4-yl)benzene

1,4-bis(benzocyclobuten-4-yl)benzene

Conditions
ConditionsYield
With lithium hydroxide; tetrabutylammomium bromide; palladium dichloride In ethanol at 20℃; for 6h; Suzuki coupling;98%
4-(4-bromophenyl)bromobenzene
92-86-4

4-(4-bromophenyl)bromobenzene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

4,4'-bis(benzylocyclobuten-4-yl)biphenyl

4,4'-bis(benzylocyclobuten-4-yl)biphenyl

Conditions
ConditionsYield
With borax; tetrabutylammomium bromide; palladium dichloride In ethanol at 20℃; for 8h; Suzuki coupling;98%
4-bromobenzocyclobutene
1073-39-8

4-bromobenzocyclobutene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

4-(benzocyclobuten-4-yl)benzocyclobutene

4-(benzocyclobuten-4-yl)benzocyclobutene

Conditions
ConditionsYield
With borax; tetrabutylammomium bromide; palladium dichloride In ethanol at 20℃; Suzuki coupling;96%
12-bromodehydroabietic acid

12-bromodehydroabietic acid

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

C28H34O2

C28H34O2

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water at 60℃; for 10h; Suzuki Coupling; Inert atmosphere;90%
2,7-dibromo-9,9-bis(4-hexyloxyphenyl)fluorene

2,7-dibromo-9,9-bis(4-hexyloxyphenyl)fluorene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

C53H54O2

C53H54O2

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In toluene at 75℃; for 12h; Suzuki Coupling; Inert atmosphere;85%
1-bromo-3,5-dichlorobenzene
19752-55-7

1-bromo-3,5-dichlorobenzene

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

C14H10Cl2

C14H10Cl2

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; toluene at 90℃; for 12h; Inert atmosphere;60%
C37H44Br2O2Si2

C37H44Br2O2Si2

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

C53H58O2Si2

C53H58O2Si2

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; toluene at 80℃; for 10.5h; Inert atmosphere;56.5%
(3aR,4S,6R,6aR)-tetrahydro-6-methoxy-2,2-dimethylfuro-[3,4-d][1,3]dioxole-4-carbaldehyde
33985-40-9

(3aR,4S,6R,6aR)-tetrahydro-6-methoxy-2,2-dimethylfuro-[3,4-d][1,3]dioxole-4-carbaldehyde

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

(R)-[(3aR,4R,6R,6aR)-4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-(4-bicyclo[4.2.0]octa-1,3,5-trienyl)methanol

(R)-[(3aR,4R,6R,6aR)-4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-(4-bicyclo[4.2.0]octa-1,3,5-trienyl)methanol

Conditions
ConditionsYield
Stage #1: 4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid With diethylzinc In toluene at 25 - 60℃; for 1h;
Stage #2: (3aR,4S,6R,6aR)-tetrahydro-6-methoxy-2,2-dimethylfuro-[3,4-d][1,3]dioxole-4-carbaldehyde In toluene at 60℃; for 2h;
55.8%
C41H52Br2O2Si2

C41H52Br2O2Si2

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

C57H66O2Si2

C57H66O2Si2

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; toluene at 80℃; for 10.5h; Inert atmosphere;52%
N,N'-didodecyl-1,6,7,12-tetrabromoperylene-3,4,9,10-tetracarboxylic acid bisimide
1158651-91-2

N,N'-didodecyl-1,6,7,12-tetrabromoperylene-3,4,9,10-tetracarboxylic acid bisimide

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

N,N'-didocananyl-1,6,7,12-tetra(4-benzocyclobutenyl)perylene-3,4,9,10-tetracarboxylic acid bisimide

N,N'-didocananyl-1,6,7,12-tetra(4-benzocyclobutenyl)perylene-3,4,9,10-tetracarboxylic acid bisimide

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride; silver(l) oxide In 1,2-dimethoxyethane at 80℃; for 24h; Suzuki coupling; Inert atmosphere;45%
Reaxys ID: 33726854

Reaxys ID: 33726854

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

Reaxys ID: 33726853

Reaxys ID: 33726853

12-bromodehydroabietic acid
33573-31-8

12-bromodehydroabietic acid

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

12-(benzocyclobutene)dehydroabietic acid

12-(benzocyclobutene)dehydroabietic acid

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water at 60℃; for 10h; Solvent; Reagent/catalyst; Inert atmosphere;
With tetrakis(triphenylphosphine) palladium(0) In ethanol; water at 60℃; for 10h; Temperature; Suzuki Coupling; Inert atmosphere;
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water at 60℃; for 10h; Temperature; Solvent; Reagent/catalyst; Suzuki Coupling; Inert atmosphere;
4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

[(R)-[(3aR,4R,6R,6aR)-4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-(4-bicyclo[4.2.0]octa-1,3,5-trienyl)methyl] 4-phenylbenzoate

[(R)-[(3aR,4R,6R,6aR)-4-methoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-(4-bicyclo[4.2.0]octa-1,3,5-trienyl)methyl] 4-phenylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: diethylzinc / toluene / 1 h / 25 - 60 °C
1.2: 2 h / 60 °C
2.1: triphenylphosphine; diisopropyl (E)-azodicarboxylate / toluene / 3 h / 0 - 25 °C
View Scheme
4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

[(R)-bicyclo[4.2.0]octa-1,3,5-trien-3-yl-[(2S,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl] 4-phenylbenzoate

[(R)-bicyclo[4.2.0]octa-1,3,5-trien-3-yl-[(2S,3S,4R)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl] 4-phenylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: diethylzinc / toluene / 1 h / 25 - 60 °C
1.2: 2 h / 60 °C
2.1: triphenylphosphine; diisopropyl (E)-azodicarboxylate / toluene / 3 h / 0 - 25 °C
3.1: trifluoroacetic acid; water / 36 h / 40 °C
View Scheme
4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

(2R,3R,4S,5R)-2-(4-amino-5-fluoro-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-4-bicyclo[4.2.0]octa-1,3,5-trienyl(hydroxy)methyl]tetrahydrofuran-3,4-diol hydrochloride

(2R,3R,4S,5R)-2-(4-amino-5-fluoro-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-4-bicyclo[4.2.0]octa-1,3,5-trienyl(hydroxy)methyl]tetrahydrofuran-3,4-diol hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: diethylzinc / toluene / 1 h / 25 - 60 °C
1.2: 2 h / 60 °C
2.1: triphenylphosphine; diisopropyl (E)-azodicarboxylate / toluene / 3 h / 0 - 25 °C
3.1: trifluoroacetic acid; water / 36 h / 40 °C
4.1: pyridine; tributylphosphine; diisopropyl (E)-azodicarboxylate / tetrahydrofuran / 2 h / 25 °C
5.1: ammonium hydroxide / 1,4-dioxane / 16 h / 120 °C
View Scheme
4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid
195730-31-5

4-bicyclo[4.2.0]octa-1,3,5-trienylboronic acid

[(R)-bicyclo[4.2.0]octa-1,3,5-trien-3-yl-[(2S,3S,4R,5R)-5-(4-chloro-5-fluoro-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl] 4-phenylbenzoate

[(R)-bicyclo[4.2.0]octa-1,3,5-trien-3-yl-[(2S,3S,4R,5R)-5-(4-chloro-5-fluoro-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl] 4-phenylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: diethylzinc / toluene / 1 h / 25 - 60 °C
1.2: 2 h / 60 °C
2.1: triphenylphosphine; diisopropyl (E)-azodicarboxylate / toluene / 3 h / 0 - 25 °C
3.1: trifluoroacetic acid; water / 36 h / 40 °C
4.1: pyridine; tributylphosphine; diisopropyl (E)-azodicarboxylate / tetrahydrofuran / 2 h / 25 °C
View Scheme

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