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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole Manufacturer/High quality/Best price/In stock

Cas:198479-63-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Think Chemical Co. Ltd

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole CAS No.:198479-63-9 Name: 3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole Molecular Structure Molecular F

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)-phenyl]-1H-indole

Cas:198479-63-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE Basic information Product Name: 3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE Synonyms: 3-METHYL-5-(PH

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Cas:198479-63-9

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 198479-63-9 with best quality

Cas:198479-63-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name 3-methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1h-indole Synonyms 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1h-indole;

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole CAS: 198479-63-9

Cas:198479-63-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 198479-63-9 5-(Benzyloxy) with best price

Cas:198479-63-9

Min.Order:10 Gram

Negotiable

Type:Other

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Qingdao Beluga Import and Export Co., LTD

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE CAS:198479-63-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermedia

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE CAS:198479-63-9

Cas:198479-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE CAS:198479-63-9

Cas:198479-63-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Indole,3-methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-

Cas:198479-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole

Cas:198479-63-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Bazedoxifene intermediate 198479-63-9

Cas:198479-63-9

Min.Order:50 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-(Benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Cas:198479-63-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole

Cas:198479-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Indole,3-methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-

Cas:198479-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

3-Methyl-5-(phenylMethoxy)-2-[4-(phenylMethoxy)phenyl]-1H-indole/High quality/Best price

Cas:198479-63-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole CAS NO.198479-63-9

Cas:198479-63-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 3-Methyl-5-(Phenylmethoxy)-2-[4-(Phenylmethoxy)Phenyl]-1H-Indole CAS No.:198479-63-9 Molecule Formula:C29H25NO2 Molecule Weight:419.53 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enter

High Quality 3-Methyl-5-(Phenylmethoxy)-2-[4-(Phenylmethoxy)Phenyl]-1H-Indole on stock

Cas:198479-63-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE

Cas:198479-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE

Cas:198479-63-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE Basic information Product Name: 3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE Synonyms: 3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE;1H-Ind

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE

Cas:198479-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-(Benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Cas:198479-63-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

3-methyl-5-phenylmethoxy-2-(4-phenylmethoxyphenyl)-1H-indole

Cas:198479-63-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

My Company Changchun Artel Import and Export trade companyImport and Export Trade Co., Ltd.is located in Changchun, a national historical and cultural city, Jilin Province, China. It covers an area of 22,000 square meters, construction area

3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole Manufacturer CAS NO.198479-63-9

Cas:198479-63-9

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-METHYL-5-(PHENYLMETHOXY)-2-[4-(PHENYLMETHOXY)PHENYL]-1H-INDOLE

Cas:198479-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5-(Benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Cas:198479-63-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

1H-Indole, 3-Methyl-5-(phenylMethoxy)-2-[4-(phenylMethoxy)phenyl]-

Cas:198479-63-9

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

5-(Benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Cas:198479-63-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

5-(Benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Cas:198479-63-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Synthetic route

1-<4-(benzyloxy)phenyl>-2-bromo-1-propanone
35081-45-9

1-<4-(benzyloxy)phenyl>-2-bromo-1-propanone

4-benzyloxyaniline hydrochloride
51388-20-6

4-benzyloxyaniline hydrochloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 115℃; for 4h; Temperature; Reagent/catalyst;94.6%
Stage #1: 1-<4-(benzyloxy)phenyl>-2-bromo-1-propanone; 4-benzyloxyaniline hydrochloride With triethylamine In butan-1-ol at 118℃; for 3h; Bischler-Moehlau Indole Synthesis;
Stage #2: With hydrogenchloride In water; butan-1-ol at 118℃; for 7h; Temperature; Reagent/catalyst; Bischler-Moehlau Indole Synthesis;
90.5%
With triethylamine In N,N-dimethyl-formamide at 120 - 150℃; for 4h; Bischler indole synthesis; Inert atmosphere;84.9%
4-benzyloxypropiophenone
4495-66-3

4-benzyloxypropiophenone

4-benzyloxyphenylhydrazine hydrochloride
52068-30-1

4-benzyloxyphenylhydrazine hydrochloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
With acetic acid In ethanol at 75 - 80℃; Product distribution / selectivity;94%
acetic acid In ethanol at 75 - 80℃; for 12h; Product distribution / selectivity;94%
With hydrogenchloride In ethanol for 2h; Reflux;84%
C33H27N3O2

C33H27N3O2

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
With sodium ethanolate In ethanol; dimethyl sulfoxide at 100℃; for 20h;85%
With sodium ethanolate In dimethyl sulfoxide at 130℃;72%
1-(4-benzyloxyphenyl)-2-morpholin-4-yl-propan-1-one

1-(4-benzyloxyphenyl)-2-morpholin-4-yl-propan-1-one

4-benzyloxyaniline hydrochloride
51388-20-6

4-benzyloxyaniline hydrochloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
In chlorobenzene at 125 - 130℃; for 8h; Large scale;83.5%
1-(4-benzyloxyphenyl)-2-(4-benzyloxy-phenylamino)-1-propanone
1048697-94-4

1-(4-benzyloxyphenyl)-2-(4-benzyloxy-phenylamino)-1-propanone

4-benzyloxyaniline hydrochloride
51388-20-6

4-benzyloxyaniline hydrochloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
In isopropyl alcohol at 110 - 115℃; for 5h; Product distribution / selectivity;82%
In ethanol at 110 - 115℃; for 5h; Product distribution / selectivity;79%
1-(4-benzyloxyphenyl)-2-(4-benzyloxy-phenylamino)-1-propanone
1048697-94-4

1-(4-benzyloxyphenyl)-2-(4-benzyloxy-phenylamino)-1-propanone

p-benzyloxyaniline
6373-46-2

p-benzyloxyaniline

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
In 2-ethoxy-ethanol for 6h; Reflux;80.5%
4’-benzyloxy-2-bromophenyl propiophenone

4’-benzyloxy-2-bromophenyl propiophenone

4-benzyloxyaniline hydrochloride
51388-20-6

4-benzyloxyaniline hydrochloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 2.5h; Reflux;65%
4’-benzyloxy-2-bromophenyl propiophenone

4’-benzyloxy-2-bromophenyl propiophenone

p-benzyloxyaniline
6373-46-2

p-benzyloxyaniline

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
In dichloromethane; ethyl acetate; N,N-dimethyl-formamide33%
In dichloromethane; ethyl acetate; N,N-dimethyl-formamide33%
In dichloromethane; ethyl acetate; N,N-dimethyl-formamide33%
4-benzyloxy-2-bromophenylpropiophenone

4-benzyloxy-2-bromophenylpropiophenone

p-benzyloxyaniline
6373-46-2

p-benzyloxyaniline

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
In dichloromethane; ethyl acetate; N,N-dimethyl-formamide33%
p-benzyloxyaniline
6373-46-2

p-benzyloxyaniline

4-benzyloxypropiophenone
4495-66-3

4-benzyloxypropiophenone

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 125℃; for 6h;23%
4-benzyloxypropiophenone
4495-66-3

4-benzyloxypropiophenone

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bromine / acetic acid / 3 h / 0 - 20 °C
2: triethylamine / N,N-dimethyl-formamide / 4 h / 120 - 150 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: bromine / 1,4-dioxane; methanol / 1 h / 20 °C
2: triethylamine / ethanol / 5 h / 20 °C
3: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: aluminum (III) chloride; bromine / toluene; methanol / 40 - 45 °C / Large scale
2: toluene / 2 h / 110 °C / Reflux; Large scale
3: chlorobenzene / 8 h / 125 - 130 °C / Large scale
View Scheme
Multi-step reaction with 2 steps
1: bromine; acetic acid / 1 h / 0 °C
2: triethylamine / N,N-dimethyl-formamide / 5 h / 120 - 150 °C
View Scheme
benzyl bromide
100-39-0

benzyl bromide

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 60 °C
2: bromine / acetic acid / 3 h / 0 - 20 °C
3: triethylamine / N,N-dimethyl-formamide / 4 h / 120 - 150 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 60 °C
2: triethylamine / N,N-dimethyl-formamide / 6 h / 125 °C
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 18 h / Reflux
2: bromine; acetic acid / 1 h / 0 °C
3: triethylamine / N,N-dimethyl-formamide / 5 h / 120 - 150 °C
View Scheme
4-hydroxypropiophenone
70-70-2

4-hydroxypropiophenone

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 60 °C
2: bromine / acetic acid / 3 h / 0 - 20 °C
3: triethylamine / N,N-dimethyl-formamide / 4 h / 120 - 150 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 16 h / 20 °C / Inert atmosphere
2: hydrogenchloride / ethanol / 2 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: potassium carbonate / acetone / 24 h / Reflux
2: bromine / 1,4-dioxane; methanol / 1 h / 20 °C
3: triethylamine / ethanol / 5 h / 20 °C
4: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
1-<4-(benzyloxy)phenyl>-2-bromo-1-propanone
35081-45-9

1-<4-(benzyloxy)phenyl>-2-bromo-1-propanone

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine / ethanol / 5 h / 20 °C
2: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: toluene / 2 h / 110 °C / Reflux; Large scale
2: chlorobenzene / 8 h / 125 - 130 °C / Large scale
View Scheme
4-nitro-phenol
100-02-7

4-nitro-phenol

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 24 h / Reflux
2: tin(ll) chloride / ethanol / 24 h / 45 °C / Inert atmosphere
3: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
benzyl chloride
100-44-7

benzyl chloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 24 h / Reflux
2: tin(ll) chloride / ethanol / 24 h / 45 °C / Inert atmosphere
3: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: potassium carbonate / acetone / 24 h / Reflux
2: bromine / 1,4-dioxane; methanol / 1 h / 20 °C
3: triethylamine / ethanol / 5 h / 20 °C
4: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1.1: tetrabutylammomium bromide / toluene; water / 90 °C / Reflux; Large scale
1.2: Reflux; Large scale
2.1: aluminum (III) chloride; bromine / toluene; methanol / 40 - 45 °C / Large scale
3.1: toluene / 2 h / 110 °C / Reflux; Large scale
4.1: chlorobenzene / 8 h / 125 - 130 °C / Large scale
View Scheme
benzyl 4-nitrophenyl ether
1145-76-2

benzyl 4-nitrophenyl ether

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tin(ll) chloride / ethanol / 24 h / 45 °C / Inert atmosphere
2: 2-ethoxy-ethanol / 6 h / Reflux
View Scheme
1-{2-[4-(chloromethyl)phenoxy]ethyl}hexahydro-1H-azepine hydrochloride
223251-25-0

1-{2-[4-(chloromethyl)phenoxy]ethyl}hexahydro-1H-azepine hydrochloride

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-[4-(2-azepan-1-yl-ethoxy)-benzyl]-1H-indole
198480-21-6

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-[4-(2-azepan-1-yl-ethoxy)-benzyl]-1H-indole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 10h; Time; Reagent/catalyst;93.7%
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydroxide In water; dimethyl sulfoxide at 20℃; for 1h; Large scale;
Stage #2: 1-{2-[4-(chloromethyl)phenoxy]ethyl}hexahydro-1H-azepine hydrochloride In dimethyl sulfoxide; N,N-dimethyl-formamide at 20℃; for 1h; Solvent; Time; Large scale;
91.8%
With sodium hydride In N,N-dimethyl acetamide at 0 - 10℃; for 0.5h; Large scale;82.6%
(4-chloromethylphenoxy)acetonitrile
112772-83-5

(4-chloromethylphenoxy)acetonitrile

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

{4-[5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-indol-1-ylmethyl]-phenoxy}-acetonitrile
1251936-40-9

{4-[5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-indol-1-ylmethyl]-phenoxy}-acetonitrile

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium amide In N,N-dimethyl-formamide at 10 - 15℃; for 0.25h;
Stage #2: 4-chloromethyl phenoxy acetonitrile In N,N-dimethyl-formamide at 10 - 15℃;
80%
5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
91444-54-1

2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In tetrahydrofuran; ethanol at 20℃;78.3%
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
1.2: 2.5 h / 0 °C / Inert atmosphere; Reflux
2.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; ethyl acetate / 0.5 h
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
1.2: 2.5 h / 0 °C / Inert atmosphere; Reflux
2.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; ethyl acetate / 0.5 h
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
1.2: 2.5 h / 0 °C / Inert atmosphere; Reflux
2.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol; ethyl acetate / 0.5 h
View Scheme
tert-butyl (4-(4-(bromomethyl)phenoxy)butyl)carbamate

tert-butyl (4-(4-(bromomethyl)phenoxy)butyl)carbamate

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

tert-butyl (4-(4-((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)phenoxy)butyl)carbamate

tert-butyl (4-(4-((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)phenoxy)butyl)carbamate

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: tert-butyl (4-(4-(bromomethyl)phenoxy)butyl)carbamate In N,N-dimethyl-formamide at 0 - 20℃; for 12h;
73%
4-(benzyloxy)benzyl bromide
5544-60-5

4-(benzyloxy)benzyl bromide

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

1-(4-(benzyloxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

1-(4-(benzyloxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

B

3-(4-(benzyloxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole

3-(4-(benzyloxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 4-(benzyloxy)benzyl bromide In tetrahydrofuran at 0℃; for 2.5h; Inert atmosphere; Reflux;
A 68%
B 30%
4-Fluorobenzyl bromide
459-46-1

4-Fluorobenzyl bromide

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

3-(4-fluorobenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole

3-(4-fluorobenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole

B

1-(4-fluorobenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

1-(4-fluorobenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 4-Fluorobenzyl bromide In tetrahydrofuran at 0℃; for 2.5h; Inert atmosphere; Reflux;
A 23%
B 68%
1-[(S)-2-(4-Chloromethyl-phenoxy)-1-methyl-ethyl]-pyrrolidine
869006-43-9

1-[(S)-2-(4-Chloromethyl-phenoxy)-1-methyl-ethyl]-pyrrolidine

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-[4-(2-pyrrolidin-1-yl-propoxy)-benzyl]-1H-indole
869006-49-5

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-[4-(2-pyrrolidin-1-yl-propoxy)-benzyl]-1H-indole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide67%
(R)-1-[2-(4-Chloromethyl-phenoxy)-ethyl]-3-methyl-pyrrolidine
869006-41-7

(R)-1-[2-(4-Chloromethyl-phenoxy)-ethyl]-3-methyl-pyrrolidine

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-{4-[2-(3-methyl-pyrrolidin-1-yl)-ethoxy]-benzyl}-1H-indole
869006-47-3

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1-{4-[2-(3-methyl-pyrrolidin-1-yl)-ethoxy]-benzyl}-1H-indole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide67%
1 ,6-dibromohexane
629-03-8

1 ,6-dibromohexane

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

1,6-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)hexane

1,6-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)hexane

B

C35H36BrNO2

C35H36BrNO2

C

C35H36BrNO2

C35H36BrNO2

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 1 ,6-dibromohexane In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
A 26%
B 66%
C 12%
1-(bromomethyl)-4-(triphenylmethoxy)benzene
1215269-88-7

1-(bromomethyl)-4-(triphenylmethoxy)benzene

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-(benzyloxy)-2-[4-(benzyloxy)phenyl]-3-methyl-1-[[4-(triphenylmethoxy)phenyl]methyl]-1H-indole

5-(benzyloxy)-2-[4-(benzyloxy)phenyl]-3-methyl-1-[[4-(triphenylmethoxy)phenyl]methyl]-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: 1-(bromomethyl)-4-(triphenylmethoxy)benzene In N,N-dimethyl-formamide at 0℃; for 2h;
66%
1,5-dibromo-pentane
111-24-0

1,5-dibromo-pentane

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

1,5-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)pentane

1,5-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)pentane

B

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(5-bromopentyl)-3-methyl-3H-indole

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(5-bromopentyl)-3-methyl-3H-indole

C

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(5-bromopentyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(5-bromopentyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 1,5-dibromo-pentane In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
A 22%
B 9%
C 65%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole

B

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(4-bromobutyl)-3-methyl-3H-indole

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(4-bromobutyl)-3-methyl-3H-indole

C

1,4-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)butane

1,4-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)butane

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 1,4-dibromo-butane In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
A 63%
B 17%
C 20%
1,4-bis(bromomethyl)benzene
623-24-5

1,4-bis(bromomethyl)benzene

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-(bromomethyl)benzyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-(bromomethyl)benzyl)-3-methyl-1H-indole

B

1,4-bis((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)benzene

1,4-bis((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)benzene

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 1,4-bis(bromomethyl)benzene In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
A 22%
B 63%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-bromobutyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide for 0.666667h;
Stage #2: 1,4-dibromo-butane With N,N-dimethyl-formamide at 20℃; for 2.5h;
60.6%
2-(4-bromomethylphenoxy)ethyl 4-methylbenzenesulfonate
1343413-04-6

2-(4-bromomethylphenoxy)ethyl 4-methylbenzenesulfonate

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

C45H41NO6S

C45H41NO6S

B

2-(4-{[5-(benzyloxy)-2-[4-(benzyloxy)phenyl]-3-methyl-1H-indol-1-yl]methyl}phenoxy)ethyl 4-methylbenzene-1-sulfonate
1343413-11-5

2-(4-{[5-(benzyloxy)-2-[4-(benzyloxy)phenyl]-3-methyl-1H-indol-1-yl]methyl}phenoxy)ethyl 4-methylbenzene-1-sulfonate

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at -10 - -5℃; for 0.5h;
Stage #2: 2-(4-bromomethylphenoxy)ethyl 4-methylbenzenesulfonate In N,N-dimethyl-formamide at -5 - 0℃; for 3h;
Stage #3: With acetic acid In N,N-dimethyl-formamide
A n/a
B 60%
1,8-dibromooctane
4549-32-0

1,8-dibromooctane

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(8-bromooctyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(8-bromooctyl)-3-methyl-1H-indole

B

1,8-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)octane

1,8-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)octane

C

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(8-bromooctyl)-3-methyl-3H-indole

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(8-bromooctyl)-3-methyl-3H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 1,8-dibromooctane In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
A 60%
B 22%
C 13%
ethyl [p-(chloromethyl)phenoxy]acetate
80494-75-3

ethyl [p-(chloromethyl)phenoxy]acetate

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

{4-[5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-indol-1-ylmethyl]-phenoxy}-acetic acid ethyl ester
198479-82-2

{4-[5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-indol-1-ylmethyl]-phenoxy}-acetic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.333333h;
Stage #2: ethyl [p-(chloromethyl)phenoxy]acetate In N,N-dimethyl-formamide at 20℃; for 18h; Further stages.;
59%
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.333333h;
Stage #2: ethyl [p-(chloromethyl)phenoxy]acetate In N,N-dimethyl-formamide at 20℃;
29.7%
1,12-dibromododecane
3344-70-5

1,12-dibromododecane

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(12-bromododecyl)-3-methyl-3H-indole

6-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-(12-bromododecyl)-3-methyl-3H-indole

B

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(12-bromododecyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(12-bromododecyl)-3-methyl-1H-indole

C

1,12-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)dodecane

1,12-bis(5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)dodecane

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 1,12-dibromododecane In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
A 11%
B 59%
C 30%
3,4,5-trimethoxybenzyl bromide
21852-50-6

3,4,5-trimethoxybenzyl bromide

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

A

3-(3,4,5-trimethoxybenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole

3-(3,4,5-trimethoxybenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole

B

1-(3,4,5-trimethoxybenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

1-(3,4,5-trimethoxybenzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 3,4,5-trimethoxybenzyl bromide In tetrahydrofuran at 0℃; for 2.5h; Inert atmosphere; Reflux;
A 17%
B 51%
3-phenoxypropyl bromide
588-63-6

3-phenoxypropyl bromide

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-(bezyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1-(3-phenoxypropyl)-1H-indole

5-(bezyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1-(3-phenoxypropyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: 3-phenoxypropyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 2h; Inert atmosphere;
46.7%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-(benzyloxy)-1-(2-(benzyloxy)ethyl)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

5-(benzyloxy)-1-(2-(benzyloxy)ethyl)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: bromoethyl-2-benzyl ether In tetrahydrofuran at 0℃; for 2.5h; Inert atmosphere; Reflux;
43%
phenoxyethyl bromide
589-10-6

phenoxyethyl bromide

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole
198479-63-9

5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1-(2-phenoxyethyl)-1H-indole

5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1-(2-phenoxyethyl)-1H-indole

Conditions
ConditionsYield
Stage #1: 5-benzyloxy-2-(4-benzyloxy-phenyl)-3-methyl-1H-indole With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: phenoxyethyl bromide In N,N-dimethyl-formamide at 0 - 20℃; for 2h; Inert atmosphere;
41.2%

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