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Anhui Dexinjia Biopharm Co., Ltd

As a leading and professional manufacturer of APIs and API intermediates in China,Anhui Dexinjia Biopharm Co., Ltd founded in 2006, Except for the R&D center, our company has built a close cooperation relation with Chinese Academy of Sciences,

2-Bromoethylbenzyl ether

Cas:1462-37-9

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Benzyl 2-bromoethyl ether Manufacturer/High quality/Best price/In stock

Cas:1462-37-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Benzyl 2-Bromoethyl Ether supplier in China

Cas:1462-37-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

BENZYL 2-BROMOETHYL ETHER

Cas:1462-37-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Benzyl 2-Bromoethyl Ether

Cas:1462-37-9

Min.Order:1

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

Benzyl 2-bromoethyl ether

Cas:1462-37-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Benzyl 2-bromoethyl ether

Cas:1462-37-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

High purity CAS 1462-37-9 BENZYL 2-BROMOETHYL ETHER in stock Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED intermediates (

High purity CAS 1462-37-9 BENZYL 2-BROMOETHYL ETHER in stock

Cas:1462-37-9

Min.Order:1 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 1462-37-9 with best quality

Cas:1462-37-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

Benzyl 2-Bromoethyl Ether CAS NO.1462-37-9

Cas:1462-37-9

Min.Order:1 Kilogram

FOB Price: $2.0 / 6.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 1462-37-9 ((2-Bromoethoxy)methyl)benzene

Cas:1462-37-9

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

BENZYL 2-BROMOETHYL ETHER CAS NO 1462-37-9

Cas:1462-37-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzene,[(2-bromoethoxy)methyl]- 1462-37-9

Cas:1462-37-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: BENZYL 2-BROMOETHYL ETHER CAS: 1462-37-9 MF: C9H11BrO MW: 215.09 EINECS: 629-202-2 Mol File: 1462-37-9.mol BENZYL 2-BROMOETHYL ETHER Structure BENZYL 2-BROMOETHYL ETHER Chemical Properties Boiling point 254 °

BENZYL 2-BROMOETHYL ETHER

Cas:1462-37-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Benzyl 2-bromoethyl ether

Cas:1462-37-9

Min.Order:1 Kilogram

FOB Price: $85.0 / 96.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

BENZYL 2-BROMOETHYL ETHER CAS:1462-37-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

BENZYL 2-BROMOETHYL ETHER CAS:1462-37-9

Cas:1462-37-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzene,[(2-bromoethoxy)methyl]-

Cas:1462-37-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: BENZYL 2-BROMOETHYL ETHER Synonyms: BENZYL 2-BROMOETHYL ETHER;1-BROMO-2-BENZYLOXYETHANE;1-BENZYLOXY-2-BROMOETHANE;2-BENZYLOXY-1-BROMOETHANE;Benzyl 2-bromoethyl ether, 97 % (GC);(2-Bromoethoxymethyl)benzene;Benzyloxyethyl Bromide;2-

BENZYL 2-BROMOETHYL ETHER supplier best quality

Cas:1462-37-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzene,[(2-bromoethoxy)methyl]-

Cas:1462-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Product name: sodium metabisulfite / sodium metabisulphite Molecular weight: 190.10 Specification: 25Kg woven bag Quality guarantee period: 6 months Appearance:white powder/crystal Storage:Store in a cool,dry place and keep away fr

benzyl 2-bromoethyl ether

Cas:1462-37-9

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Benzyl 2-bromoethyl ether

Cas:1462-37-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

BENZYL 2-BROMOETHYL ETHER

Cas:1462-37-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-bromo-2-benzyloxyethane

Cas:1462-37-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzyl 2-Bromoethyl Ether

Cas:1462-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Saiwante (shanghai) New Material Technology Co., Ltd.

Appearance/Colour:Clear colorless to pale yellow liquid Vapor Pressure:0.022mmHg at 25°C Refractive Index:n20/D 1.541(lit.) Boiling Point:258.6 °C at 760 mmHg Flash Point:111.7 °C PSA:9.23000 Density:1.358 g/cm3 LogP:2.59

BENZYL 2-BROMOETHYL ETHER cas1462-37-9 high purity

Cas:1462-37-9

Min.Order:1 Gram

FOB Price: $3.0 / 6.0

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Benzyl 2-Bromoethyl Ether

Cas:1462-37-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

high quality Benzyl 2-Bromoethyl Ether supplierAppearance:Powder or crystal Storage:Keep in dry,cool and ventilated place Package:according to customers' requirements Application:Intermediate for organic syntheses Transportation:By air(EMS or EUB or

high quality Benzyl 2-Bromoethyl Ether supplier

Cas:1462-37-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Benzyl 2-bromoethyl ether

Cas:1462-37-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality moderate price & quick delivery Appearance:Clear colorless to pale yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Applicat

Benzene,[(2-bromoethoxy)methyl]-

Cas:1462-37-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

Organic Intermediate 2-Bromobutyric acid CAS 1462-37-9

Cas:1462-37-9

Min.Order:1 Liter

FOB Price: $4.5 / 5.0

Type:Trading Company

inquiry

Synthetic route

2-Benzyloxyethanol
622-08-2

2-Benzyloxyethanol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With carbon tetrabromide; triphenylphosphine In tetrahydrofuran at 0 - 20℃;98%
With N-Bromosuccinimide; triphenylphosphine In dichloromethane at -78 - 20℃; Inert atmosphere; Darkness;98%
With N-Bromosuccinimide; triphenylphosphine In dichloromethane at 20℃; for 13h;89%
2,4,6-tris(benzyloxy)-1,3,5-triazine
7285-83-8

2,4,6-tris(benzyloxy)-1,3,5-triazine

2-bromoethanol
540-51-2

2-bromoethanol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In 1,4-dioxane at 20℃; for 5h; Inert atmosphere;98%
2-bromoethanol
540-51-2

2-bromoethanol

benzyl alcohol
100-51-6

benzyl alcohol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold (I) at 150℃; for 0.5h; Inert atmosphere; Microwave irradiation;98%
2-(Benzyloxy)ethyl p-toluenesulfonate
4981-83-3

2-(Benzyloxy)ethyl p-toluenesulfonate

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With lithium bromide In acetonitrile at 70 - 80℃; for 2.5h; Reagent/catalyst; Solvent; Temperature;94.3%
Pyridine-2-sulfonic acid 2-benzyloxy-ethyl ester
123455-81-2

Pyridine-2-sulfonic acid 2-benzyloxy-ethyl ester

A

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

B

C5H4NO3S(1-)*Br(1-)*Mg(2+)

C5H4NO3S(1-)*Br(1-)*Mg(2+)

Conditions
ConditionsYield
With magnesium bromide ethyl etherate In diethyl ether; dichloromethane at 0℃; for 0.5h;A 94%
B n/a
2-(benzyloxy)ethyl methanesulfonate
58841-52-4

2-(benzyloxy)ethyl methanesulfonate

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With sodium bromide In dimethyl sulfoxide at 80 - 100℃; for 1h;93.5%
2-(benzyloxy)-4,6-dimethoxy-1,3,5-triazine

2-(benzyloxy)-4,6-dimethoxy-1,3,5-triazine

2-bromoethanol
540-51-2

2-bromoethanol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In 1,4-dioxane at 20℃; for 0.0166667h; Molecular sieve; Inert atmosphere;89%
2-Benzyloxyethanol
622-08-2

2-Benzyloxyethanol

triphenylphosphine
603-35-0

triphenylphosphine

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
In hexane; dichloromethane85%
In N-Bromosuccinimide; hexane; dichloromethane85%
2-Benzyloxyethanol
622-08-2

2-Benzyloxyethanol

A

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

B

benzyl bromide
100-39-0

benzyl bromide

Conditions
ConditionsYield
With bromine In acetonitrile at 0℃; for 0.5h; Bromination;A 77%
B n/a
carbon tetrabromide
558-13-4

carbon tetrabromide

2-Benzyloxyethanol
622-08-2

2-Benzyloxyethanol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With pyridine; triphenylphosphine In methanol; dichloromethane; ethyl acetate76%
ethylene dibromide
106-93-4

ethylene dibromide

benzyl alcohol
100-51-6

benzyl alcohol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With potassium hydroxide; tetrafluoroboric acid; mercury(II) oxide In dichloromethane 1.) room temp., 1 h;70%
oxirane
75-21-8

oxirane

benzyl bromide
100-39-0

benzyl bromide

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
With copper
1-bromo-2-(chloromethoxy)ethane
1462-35-7

1-bromo-2-(chloromethoxy)ethane

phenylmagnesium bromide

phenylmagnesium bromide

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

benzyl bromide
100-39-0

benzyl bromide

polymer-bound NMe3(1+)*SCN(1-)

polymer-bound NMe3(1+)*SCN(1-)

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 79 percent / NaH / tetrahydrofuran / 3 h / Heating
2: 89 percent / NBS; PPh3 / CH2Cl2 / 13 h / 20 °C
View Scheme
benzyl bromide
100-39-0

benzyl bromide

sodium compound of cyclohexanol

sodium compound of cyclohexanol

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaH
2: Br2, Ph3P
View Scheme
benzyl bromide
100-39-0

benzyl bromide

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydride / tetrahydrofuran / 16 h / 0 - 23 °C
2: N-Bromosuccinimide; triphenylphosphine / dichloromethane / 1 h / -10 - 23 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 0 - 20 °C
1.2: 12 h / 0 - 20 °C
2.1: N-Bromosuccinimide; triphenylphosphine / dichloromethane / 1 h / -78 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydride / tetrahydrofuran
2: triphenylphosphine; N-Bromosuccinimide / dichloromethane / 1 h / -78 - 20 °C
View Scheme
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

benzyl vinyl ether
935-04-6

benzyl vinyl ether

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 60℃; for 8h;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 60℃; for 8h;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran at 68℃; for 12h;97%
With potassium tert-butylate In tetrahydrofuran at 0 - 20℃; for 2h; Inert atmosphere;70%
With potassium tert-butylate
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

benzyl iodoethyl ether
54555-84-9

benzyl iodoethyl ether

Conditions
ConditionsYield
With sodium iodide In acetone Reflux;100%
With sodium iodide In acetone for 48h; Reflux;85%
With sodium iodide In acetone for 3h; Reflux;73%
With sodium iodide In acetone for 16h; Reflux;60%
With sodium iodide In acetone for 6h; Reflux;
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

triethyl phosphite
122-52-1

triethyl phosphite

diethyl <2-(benzyloxy)ethyl>phosphonate
727-18-4

diethyl <2-(benzyloxy)ethyl>phosphonate

Conditions
ConditionsYield
at 200℃; for 3h; Arbuzov Reaction; Inert atmosphere;98%
at 165 - 170℃; for 3h;76%
at 165 - 170℃;76%
at 170℃; for 2h;71%
piperidin-2-one
675-20-7

piperidin-2-one

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

1-(2-(benzyloxy)ethyl)piperidin-2-one
157399-43-4

1-(2-(benzyloxy)ethyl)piperidin-2-one

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran 1.) 0 deg C; 2.) heating;97%
C27H24N2O3
1057644-00-4

C27H24N2O3

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

C36H34N2O4
1057644-06-0

C36H34N2O4

Conditions
ConditionsYield
With sodium hydroxide In water; acetone Reflux;97%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

2-fluoro-4-hydroxybenzonitrile
82380-18-5

2-fluoro-4-hydroxybenzonitrile

4-(2-benzyloxy-ethoxy)-2-fluoro-benzonitrile
1409990-80-2

4-(2-benzyloxy-ethoxy)-2-fluoro-benzonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 6h;97%
3,5-dicarbomethoxypyrazole
4077-76-3

3,5-dicarbomethoxypyrazole

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

3,5-dimethyl 1-[2-(benzyloxy)ethyl]-1H-pyrazole-3,5-dicarboxylate
1200497-52-4

3,5-dimethyl 1-[2-(benzyloxy)ethyl]-1H-pyrazole-3,5-dicarboxylate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 90℃; for 4h; Inert atmosphere;96.22%
With potassium carbonate In acetonitrile at 90℃; for 4h; Inert atmosphere;96.22%
With potassium carbonate In acetonitrile at 85℃; for 1.5h;
With potassium carbonate In acetonitrile for 4.5h; Inert atmosphere; Reflux;
With potassium carbonate In acetonitrile for 4.5h; Reflux; Inert atmosphere;
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

diethyl 2-(2-(benzyloxy)ethyl)-2-methylmalonate
172644-58-5

diethyl 2-(2-(benzyloxy)ethyl)-2-methylmalonate

Conditions
ConditionsYield
Stage #1: Diethyl methylmalonate With sodium hydride In tetrahydrofuran
Stage #2: bromoethyl-2-benzyl ether In tetrahydrofuran at 90℃; for 5h;
96%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

4-(5-(trifluoromethyl)-1H-imidazol-2-yl)benzonitrile
33469-11-3

4-(5-(trifluoromethyl)-1H-imidazol-2-yl)benzonitrile

4-(1-(2-(benzyloxy)ethyl)-4-(trifluoromethyl)-1H-imidazol-2-yl)benzonitrile

4-(1-(2-(benzyloxy)ethyl)-4-(trifluoromethyl)-1H-imidazol-2-yl)benzonitrile

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 110℃; for 18h;96%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

1-(ethoxymethyl)benzene
539-30-0

1-(ethoxymethyl)benzene

Conditions
ConditionsYield
With tris-(trimethylsilyl)silane In acetonitrile at 50℃; for 24h;95%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

2-bromo-4-fluoro-phenol
496-69-5

2-bromo-4-fluoro-phenol

1-(2-(benzyloxy)ethoxy)-2-bromo-4-fluorobenzene

1-(2-(benzyloxy)ethoxy)-2-bromo-4-fluorobenzene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 16h;95%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol hydrochloride

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol hydrochloride

Umeclidinium bromide

Umeclidinium bromide

Conditions
ConditionsYield
In propan-1-ol; water for 2h; Solvent; Reflux;94.01%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol hydrobromide

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol hydrobromide

Umeclidinium bromide

Umeclidinium bromide

Conditions
ConditionsYield
In 2-methyltetrahydrofuran; water for 2.5h; Reflux;93.25%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

meta-hydroxybenzaldehyde
100-83-4

meta-hydroxybenzaldehyde

3-(2-(benzyloxy)ethoxy)benzaldehyde
1141781-75-0

3-(2-(benzyloxy)ethoxy)benzaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 24h; Large scale;93%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 24h; Large scale;93%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol sulfuric acid

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol sulfuric acid

Umeclidinium bromide

Umeclidinium bromide

Conditions
ConditionsYield
In water; acetonitrile for 3h; Reflux;92.87%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol formic acid

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol formic acid

Umeclidinium bromide

Umeclidinium bromide

Conditions
ConditionsYield
In isopropyl alcohol for 2.5h; Reflux;92.05%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

2-(2-benzyloxyethyl)-allylmalonate
188125-31-7

2-(2-benzyloxyethyl)-allylmalonate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 12h; Alkylation; Heating;92%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

2-nitro-4-phenylmethoxy-phenol
96315-18-3

2-nitro-4-phenylmethoxy-phenol

4-(benzyloxy)-1-[2-(benzyloxy)ethoxy]-2-nitrobenzene
1257408-27-7

4-(benzyloxy)-1-[2-(benzyloxy)ethoxy]-2-nitrobenzene

Conditions
ConditionsYield
Stage #1: 2-nitro-4-phenylmethoxy-phenol With potassium carbonate In N,N-dimethyl-formamide for 0.333333h; Williamson alkylation;
Stage #2: bromoethyl-2-benzyl ether In N,N-dimethyl-formamide at 110℃; for 14h; Williamson alkylation; Inert atmosphere;
92%
4-iodopyrazole
3469-69-0

4-iodopyrazole

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

1-(2-(benzyloxy)ethyl)-4-iodo-1H-pyrazole
1562305-17-2

1-(2-(benzyloxy)ethyl)-4-iodo-1H-pyrazole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h;91.7%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h;91.7%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;20 g
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol nitric acid

(1-azabicyclo[2.2.2]octane-4-yl)(diphenyl)methanol nitric acid

Umeclidinium bromide

Umeclidinium bromide

Conditions
ConditionsYield
In 1,4-dioxane for 2h; Reflux;90.85%
diethyl <1-14C>malonate
23178-23-6

diethyl <1-14C>malonate

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

diethyl <2-(benzyloxy)ethyl><1-14C>malonate

diethyl <2-(benzyloxy)ethyl><1-14C>malonate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran for 9h; Heating;90%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

4,5-bis(hydroxy)phthalic acid dimethyl ester
66323-03-3

4,5-bis(hydroxy)phthalic acid dimethyl ester

4,5-bis(benzyloxyethoxy)phthalic acid dimethyl ester
264871-01-4

4,5-bis(benzyloxyethoxy)phthalic acid dimethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone for 48h; Etherification; Heating;90%
C25H20N2O3
263141-91-9

C25H20N2O3

bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

C34H30N2O4
263141-92-0

C34H30N2O4

Conditions
ConditionsYield
With sodium hydroxide In water; acetone for 14h; Reflux;90%
bromoethyl-2-benzyl ether
1462-37-9

bromoethyl-2-benzyl ether

3-hydroxy-5-methoxy-benzoic acid methyl ester
19520-74-2

3-hydroxy-5-methoxy-benzoic acid methyl ester

methyl 3-(2-(benzyloxy)ethoxy)-5-methoxybenzoate
203803-61-6

methyl 3-(2-(benzyloxy)ethoxy)-5-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide90%
With potassium carbonate In N,N-dimethyl-formamide90%
Stage #1: 3-hydroxy-5-methoxy-benzoic acid methyl ester With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: bromoethyl-2-benzyl ether In N,N-dimethyl-formamide at 160℃; for 2h;
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