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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Diethyl allylmalonate Manufacturer/High quality/Best price/In stock

Cas:2049-80-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Diethyl Allylmalonate supplier in China

Cas:2049-80-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Diethyl Allylmalonate

Cas:2049-80-1

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Allylmalonic acid diethyl ester

Cas:2049-80-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2049-80-12049-80-1

Cas:2049-80-1

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Diethyl allylmalonate CAS:2049-80-1

Cas:2049-80-1

Min.Order:1 Kilogram

FOB Price: $30.0 / 40.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 2049-80-1 with competitive price

Cas:2049-80-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Diethyl allylmalonateCAS2049-80-1

Cas:2049-80-1

Min.Order:1 Kilogram

FOB Price: $20.0 / 25.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Propanedioic acid,2-(2-propen-1-yl)-, 1,3-diethyl ester 2049-80-1

Cas:2049-80-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Diethyl allylmalonate CAS 2049-80-1

Cas:2049-80-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:2049-80-1

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Diethyl Allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Propanedioic acid,2-(2-propen-1-yl)-, 1,3-diethyl ester

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

1. Best quality in your requirement 2. Competitive price in China market 3. mature Technical support 4. Professional logistic support 5 . Full experience of large numbers containers loading in Chinese sea port 6 Fast shipment by reputed shipping

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:1 Kilogram

FOB Price: $156.0 / 158.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Best service,high quality and cheap price. Storage:Keep away from heat,sparks and flames. Package:25kg/50kg/200kg drum or Customer demand Application:Used as pharmaceutical intermediates Transportation:BY sea/air or by courier

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-[2-(2,5-dimethylphenoxy)ethyl]-1,3,4-thiadiazol-2-amine(SALTDATA: FREE)

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Diethyl Allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Diethyl AllylMalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Diethyl allylmalonate cas 2049-80-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Diethyl allylmalonate cas 2049-80-1

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:clear colorless to slightly yellow liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

Diethylallylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Diethyl allylmalonate 2049-80-1

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

Diethyl allylmalonate 2049-80-1

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

Diethyl allylmalonate

Cas:2049-80-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

3-(3-ethylpent-2-enoxy)-3-oxopropanoate

Cas:2049-80-1

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

allyl bromide
106-95-6

allyl bromide

diethyl malonate
105-53-3

diethyl malonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With tetrabutyl-ammonium chloride; potassium carbonate In dichloromethane; water at 80℃; for 45h;100%
98%
With P(MeNCH2CH2)3N In hexane; acetonitrile at 25℃; for 0.5h;94%
Allyl acetate
591-87-7

Allyl acetate

diethyl malonate
105-53-3

diethyl malonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With palladium diacetate; potassium fluoride on basic alumina for 0.0833333h; Trost-Tsuji reaction; microwave irradiation;98%
With C29H29N2O2PPd; potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h; Reagent/catalyst; Tsuji-Trost Allylation; Schlenk technique; Inert atmosphere;77%
With potassium fluoride on basic alumina; 1,2-bis-(diphenylphosphino)ethane; bis[1,2-bis(diphenylphosphino)ethane]palladium(0) In tetrahydrofuran for 4.5h; Ambient temperature;75%
allyl alcohol
107-18-6

allyl alcohol

diethyl malonate
105-53-3

diethyl malonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With pyridine; magnesium sulfate; 1,2-(p-MeOC6H4)2cyclobuten[=P(2,4,6-tri-t-BuPh)]2PdOTf at 50℃; for 12h;92%
With [bis(methyldiphenylsilyl)methyl]diphenylphosphine; pyridine; tetrabutyl ammonium fluoride; tris(dibenzylideneacetone)dipalladium (0) In 1,4-dioxane at 100℃; for 8h; Tsuji-Trost reaction;86%
Allyl acetate
591-87-7

Allyl acetate

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With C33H33N2O4PPd; potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h; Reagent/catalyst; Tsuji-Trost Allylation; Schlenk technique; Inert atmosphere;A 91%
B 8%
With C48H47ClN2P2Pd(1+); potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h; Reagent/catalyst; Tsuji-Trost Allylation; Schlenk technique; Inert atmosphere;A 22%
B 78%
With aluminum oxide; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 40h; Ambient temperature;A 70%
B 15%
3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

diethyl malonate
105-53-3

diethyl malonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile at 50℃; for 7h;87%
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In acetonitrile for 7h;87%
Phenyl-phosphonothioic acid S-allyl ester O-ethyl ester
74070-96-5

Phenyl-phosphonothioic acid S-allyl ester O-ethyl ester

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) at 80℃; for 0.666667h; Product distribution;A 87%
B 13%
triethyl pent-4-ene-1,2,2-tricarboxylate
16515-85-8

triethyl pent-4-ene-1,2,2-tricarboxylate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With sodium ethanolate In tetrahydrofuran for 1h; Inert atmosphere;87%
allyl methyl carbonate
35466-83-2

allyl methyl carbonate

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With triphenylphosphine In water at 50℃; for 24h;A 84%
B 4%
With triphenylphosphine; Pd-Gr In tetrahydrofuran; dodecane for 4h; Heating; Title compound not separated from byproducts;A 41 % Chromat.
B 3 % Chromat.
With tris-(dibenzylideneacetone)dipalladium(0); 2,2’-(methylenedisulfanediyl)bis(1,3-benzothiazole) In tetrahydrofuran at 70℃; for 2h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Tsuji-Trost Allylation; chemoselective reaction;
diethyl malonate
105-53-3

diethyl malonate

<(C5H5)Co3>Pd(propenyl)

<(C5H5)Co3>Pd(propenyl)

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With sodium hydride In toluene at 20℃; for 16h;82%
diethyl malonate
105-53-3

diethyl malonate

allyl halide

allyl halide

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran80%
lithium diethyl malonate
34727-00-9

lithium diethyl malonate

tetracarbonyl(ϖ-allyl)manganese

tetracarbonyl(ϖ-allyl)manganese

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether for 1.5h; -78 deg C -> r.t.; Title compound not separated from byproducts;A 13%
B 76%
allyl bromide
106-95-6

allyl bromide

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran at 0℃; for 0.25h;
Stage #2: allyl bromide In tetrahydrofuran at 0 - 25℃; for 14h; Further stages.;
A 24%
B 76%
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1h;
Stage #2: allyl bromide at 20℃; for 12h; Inert atmosphere;
A 68%
B n/a
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran at 0℃; for 1h;
Stage #2: allyl bromide In tetrahydrofuran at 20℃; for 12h;
A 68%
B 12%
acetone O-<(allyloxy)-carbonyl>oxime
17686-63-4

acetone O-<(allyloxy)-carbonyl>oxime

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
ethyl-diphenyl-phosphane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran for 1h; Ambient temperature;A 75%
B 3%
C12H13NO3
118068-86-3

C12H13NO3

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
ethyl-diphenyl-phosphane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran for 1.5h; Product distribution; Ambient temperature; variation of allylating agents, solvent, temperature and reaction time.;A 75%
B 14%
ethyl-diphenyl-phosphane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran for 1.5h; Ambient temperature;A 75%
B 14%
1-phenylethyl cyanide
1823-91-2

1-phenylethyl cyanide

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With potassium carbonate; Pd(PhCH=CH)2CO>2CO; 1,2-bis-(diphenylphosphino)ethane In N,N-dimethyl-formamide Ambient temperature;A 74%
B 26%
diethyl malonate
105-53-3

diethyl malonate

allyl-trimethyl-silane
762-72-1

allyl-trimethyl-silane

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In methanol for 4h; Ambient temperature;74%
With ammonium cerium (IV) nitrate In methanol57%
Allyl ethyl phenylphosphonothionate
74070-90-9, 97714-35-7, 97714-36-8

Allyl ethyl phenylphosphonothionate

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

C

Phenyl-phosphonothioic acid S-allyl ester O-ethyl ester
74070-96-5

Phenyl-phosphonothioic acid S-allyl ester O-ethyl ester

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) at 80℃; for 0.333333h; Product distribution;A 25%
B 2%
C 73%
allyl iodid
556-56-9

allyl iodid

diethyl malonate
105-53-3

diethyl malonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With cerium oxide nanoparticle In water at 20℃; for 12h; Green chemistry;72%
Stage #1: diethyl malonate With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 1h;
Stage #2: allyl iodid In tetrahydrofuran for 24h; Reflux;
3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: diethyl malonate With potassium tert-butylate In N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: 3-chloroprop-1-ene In N,N-dimethyl-formamide at 20℃; for 12h;
A 70%
B 5%
With potassium hydroxide; polyethylene glycol Alkylation;A 42.5%
B n/a
With potassium hydroxide; water; cetyltrimethylammonim bromide for 1h; Alkylation;A 30.9%
B n/a
With ethanol; sodium
allyltributylstanane
24850-33-7

allyltributylstanane

Diethyl 2-bromomalonate
685-87-0

Diethyl 2-bromomalonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With [Cu(2,9-bis(4-methoxyphenyl)-1,10-phenanthroline)2]Cl In acetonitrile for 4.5h; Irradiation; Inert atmosphere;70%
Diethyl 2-bromomalonate
685-87-0

Diethyl 2-bromomalonate

allyl-trimethyl-silane
762-72-1

allyl-trimethyl-silane

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With fac-tris[2-phenylpyridinato-C2,N]iridium(III) In acetonitrile at 20 - 30℃; for 24h; Inert atmosphere; Irradiation;70%
With C44H29CuN4O3P(1+)*BF4(1-) In acetonitrile at 20℃; Reagent/catalyst; UV-irradiation;64%
C10H15NO3
118068-88-5

C10H15NO3

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
ethyl-diphenyl-phosphane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran for 3h; Ambient temperature;A 69%
B 2%
4-nitro-benzaldehyde-(O-allyl-seqtrans-oxime )
50998-68-0

4-nitro-benzaldehyde-(O-allyl-seqtrans-oxime )

diethyl malonate
105-53-3

diethyl malonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With sodium diethylmalonate; ethyl-diphenyl-phosphane; bis(dibenzylideneacetone)-palladium(0) In N,N-dimethyl-formamide at 100℃; for 24h;67%
Diethyl 2-bromomalonate
685-87-0

Diethyl 2-bromomalonate

potassium trifluoro(prop-1-en-2-yl)borate

potassium trifluoro(prop-1-en-2-yl)borate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; eosin y In methanol at 20℃; Irradiation;67%
sodium diethylmalonate
996-82-7, 34727-00-9, 73177-21-6

sodium diethylmalonate

N,N,N-triethylprop-2-en-1-aminium bromide
29443-23-0

N,N,N-triethylprop-2-en-1-aminium bromide

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 24h; Ambient temperature;A 62%
B 13%
sodium diethylmalonate
996-82-7, 34727-00-9, 73177-21-6

sodium diethylmalonate

Allyl acetate
591-87-7

Allyl acetate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
diiron nonacarbonyl In tetrahydrofuran at 20℃; for 120h;61%
allyl alcohol
107-18-6

allyl alcohol

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With acetic acid; tetrakis(triphenylphosphine) palladium(0) at 100℃; for 0.166667h;A 61%
B 30%
With 1,1'-bis-(diphenylphosphino)ferrocene; nickel(II) bromide trihydrate; tetrabutylammonium acetate; zinc In N,N-dimethyl acetamide at 50℃; for 66h; Inert atmosphere;A 45%
B 6%
With bis(1,5-cyclooctadiene)nickel (0); 1,4-di(diphenylphosphino)-butane In toluene at 105℃; for 17h; Reagent/catalyst; Temperature; Inert atmosphere; Schlenk technique;A 20 %Chromat.
B 63 %Chromat.
diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With iodine In dimethyl sulfoxide at 60℃; for 0.5h; Acidic conditions;57%
With tris(triphenylphosphine)ruthenium(II) chloride; triethylaluminum In toluene at 20℃; for 36h;91 % Spectr.
With triethylaluminum; Fe(III)bis(imidazolonyl)pyridine)Cl3 In toluene at 20℃; for 24h;13 % Spectr.
allyl (N-phenyl)benzimidate
85021-16-5

allyl (N-phenyl)benzimidate

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With 1,2-bis-(diphenylphosphino)ethane; bis(dibenzylideneacetone)-palladium(0) In N,N-dimethyl-formamide for 4h; Ambient temperature;A 55%
B 28%
1-amino-2-propene
107-11-9

1-amino-2-propene

diethyl malonate
105-53-3

diethyl malonate

A

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

B

diallylmalonic acid diethyl ester
3195-24-2

diallylmalonic acid diethyl ester

Conditions
ConditionsYield
With nickel(II) bromide trihydrate; 1,4-di(diphenylphosphino)-butane; zinc In N,N-dimethyl-formamide at 80℃; for 22h; Inert atmosphere;A 55%
B 20%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

ethyl (±)-4,5-epoxy-2-(ethoxycarbonyl)pentanoate
13353-23-6

ethyl (±)-4,5-epoxy-2-(ethoxycarbonyl)pentanoate

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 15h; Ambient temperature;100%
With 3-chloro-benzenecarboperoxoic acid In chloroform for 12h; Ambient temperature;98%
With potassium peroxymonosulfate sulfate In aq. phosphate buffer; water; ethyl acetate; acetone at 20℃; pH=8;86%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

allylmalonic acid
2583-25-7

allylmalonic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol100%
With sodium hydroxide In methanol; dichloromethane at 20℃; for 1h;87%
With lithium aluminium tetrahydride In tetrahydrofuran85%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

methylenecyclopentane
1528-30-9

methylenecyclopentane

diethyl 4-methylenespiro<4.4>nonane-2,2-dicarboxylate
127220-05-7

diethyl 4-methylenespiro<4.4>nonane-2,2-dicarboxylate

Conditions
ConditionsYield
With copper diacetate; manganese triacetate In acetic acid at 70 - 75℃; for 24h;100%
N-(bromomethyl)phtalimide
5332-26-3

N-(bromomethyl)phtalimide

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

diethyl 2‐allyl‐2‐phthalimidomethylmalonate
1200242-48-3

diethyl 2‐allyl‐2‐phthalimidomethylmalonate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 0 - 25℃; Inert atmosphere;
Stage #2: N-(bromomethyl)phtalimide In tetrahydrofuran at 0 - 25℃; Inert atmosphere;
100%
formaldehyd
50-00-0

formaldehyd

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

diethyl 2-allyl-2-(hydroxymethyl)malonate
82515-47-7

diethyl 2-allyl-2-(hydroxymethyl)malonate

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethanol; water at 0 - 20℃; for 20h;99%
With sodium hydrogencarbonate In ethanol; water at 0 - 20℃; for 20h;99%
With potassium carbonate In dimethyl sulfoxide for 168h; Ambient temperature;13%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

1-bromo-2-heptyne
18495-26-6

1-bromo-2-heptyne

diethyl 2-allyl-2-(hept-2-yn-1-yl)malonate
191801-57-7

diethyl 2-allyl-2-(hept-2-yn-1-yl)malonate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h; Inert atmosphere;
Stage #2: 1-bromo-2-heptyne In tetrahydrofuran; mineral oil at 0 - 20℃; for 12h; Inert atmosphere;
99%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 20℃;
Stage #2: 1-bromo-2-heptyne In tetrahydrofuran at 20℃; for 12h; Further stages.;
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

Octa-<(3-mercaptopropyl)-silsesquioxan>
161678-48-4

Octa-<(3-mercaptopropyl)-silsesquioxan>

C104H184O44S8Si8

C104H184O44S8Si8

Conditions
ConditionsYield
With 2,2-dimethoxy-2-phenylacetophenone In tetrahydrofuran for 0.5h; UV-irradiation;98.7%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

silver allylmalonate

silver allylmalonate

Conditions
ConditionsYield
With nitric acid; silver nitrate In water98.5%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

propargyl bromide
106-96-7

propargyl bromide

4,4-bis(ethoxycarbonyl)-1-hepten-6-yne
101268-55-7

4,4-bis(ethoxycarbonyl)-1-hepten-6-yne

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran; hexane; toluene at -78℃; for 1h;98%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium ethanolate In diethyl ether; ethanol for 0.166667h; Cooling with ice; Inert atmosphere;
Stage #2: propargyl bromide In diethyl ether; ethanol at 20℃; for 1h; Cooling with ice; Inert atmosphere;
92%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: propargyl bromide In N,N-dimethyl-formamide at 0 - 25℃; for 1h; Inert atmosphere;
92%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

2,3-dimethyl-buta-1,3-diene
513-81-5

2,3-dimethyl-buta-1,3-diene

diethyl 2-(4,5-dimethyl-2-methylene-4-hexenyl)malonate

diethyl 2-(4,5-dimethyl-2-methylene-4-hexenyl)malonate

Conditions
ConditionsYield
With tetrabutylammonium borohydride; zinc(II) iodide; cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane] In dichloromethane at 40℃; for 20h;98%
With cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane]; zinc(II) iodide; zinc In dichloromethane for 20h;92%
With tetrabutylammonium borohydride; zinc(II) iodide; cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane] In dichloromethane at 40℃; for 16h;81%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

1,4-Dichloro-2-butyne
821-10-3

1,4-Dichloro-2-butyne

tetraethyl dodeca-1,11-dien-6-yne-4,4,9,9-tetracarboxylate
1193378-70-9

tetraethyl dodeca-1,11-dien-6-yne-4,4,9,9-tetracarboxylate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide at 0℃;
Stage #2: 1,4-Dichloro-2-butyne In tetrahydrofuran; N,N-dimethyl-formamide at 0 - 20℃;
98%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

2-(methylsulfanyl)benzaldehyde
7022-45-9

2-(methylsulfanyl)benzaldehyde

1,3-diethyl 2-(4-(2-(methylthio)phenyl)-4-oxobutyl)malonate
1362860-33-0

1,3-diethyl 2-(4-(2-(methylthio)phenyl)-4-oxobutyl)malonate

Conditions
ConditionsYield
With C21H44N2P2Rh*C32H12BF24 In acetone at 55℃; for 3h; Inert atmosphere;98%
With [Rh(η6-C6H5F)(bis(dicyclohexylphosphino)methane)][B(C6H3-3,5-(CF3)2)4] In 1,2-dichloro-ethane at 80℃; for 2h; Inert atmosphere;
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

(Z)-3-fluoro-3-phenylallyl 2,2,2-trifluoroacetate

(Z)-3-fluoro-3-phenylallyl 2,2,2-trifluoroacetate

diethyl (S)-2-allyl-2-(1-fluoro-1-phenylallyl)malonate

diethyl (S)-2-allyl-2-(1-fluoro-1-phenylallyl)malonate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 65℃; for 0.166667h; Sealed tube;
Stage #2: (Z)-3-fluoro-3-phenylallyl 2,2,2-trifluoroacetate With C51H54IrNO4P(1+)*BF4(1-) In tetrahydrofuran at 20℃; for 2h; Inert atmosphere; enantioselective reaction;
98%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

methyl iodide
74-88-4

methyl iodide

diethyl allylmethylmalonate
53651-72-2

diethyl allylmethylmalonate

Conditions
ConditionsYield
97%
With sodium methylate
With sodium ethanolate
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

bromoacetic acid tert-butyl ester
5292-43-3

bromoacetic acid tert-butyl ester

2-Allyl-2-ethoxycarbonyl-succinic acid 4-tert-butyl ester 1-ethyl ester
193806-54-1

2-Allyl-2-ethoxycarbonyl-succinic acid 4-tert-butyl ester 1-ethyl ester

Conditions
ConditionsYield
With sodium hydride96%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: bromoacetic acid tert-butyl ester In tetrahydrofuran; mineral oil at 20℃; for 16h;
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

ethylene dibromide
106-93-4

ethylene dibromide

diethyl (+/-)-(2-bromoethyl)(2-propenyl)propanedioate
174619-42-2

diethyl (+/-)-(2-bromoethyl)(2-propenyl)propanedioate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 20℃; for 1h;
Stage #2: ethylene dibromide In tetrahydrofuran at 20℃; for 15h;
96%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 1.5h; Inert atmosphere;
Stage #2: ethylene dibromide In tetrahydrofuran; mineral oil at 20℃; for 15.5h; Inert atmosphere;
96%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 20℃; for 1h;
Stage #2: ethylene dibromide In tetrahydrofuran at 20℃; for 15h;
81%
C39H53NO3*C24H32O8*F6P(1-)*H(1+)

C39H53NO3*C24H32O8*F6P(1-)*H(1+)

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

C40H59NO5*C24H32O8*F6P(1-)*H(1+)

C40H59NO5*C24H32O8*F6P(1-)*H(1+)

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran
Stage #2: C39H53NO3*C24H32O8*F6P(1-)*H(1+) With 1,3-bis-(diphenylphosphino)propane; palladium diacetate In tetrahydrofuran at 20℃; for 20h; Tsuji-Trost allylation;
96%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

(Z)-1-bromo-3-methylpent-2-en-4-yne
85850-08-4

(Z)-1-bromo-3-methylpent-2-en-4-yne

2-allyl-2-((Z)-3-methyl-pent-2-en-4-ynyl)-malonic acid diethyl ester
1187458-52-1

2-allyl-2-((Z)-3-methyl-pent-2-en-4-ynyl)-malonic acid diethyl ester

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran Inert atmosphere;
Stage #2: (Z)-1-bromo-3-methylpent-2-en-4-yne In tetrahydrofuran Inert atmosphere;
96%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

2-allyl-1,3-propanediol
42201-43-4

2-allyl-1,3-propanediol

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 4.5h;
Stage #2: With water; sodium hydroxide In tetrahydrofuran at 0 - 20℃; for 0.166667h;
95%
With lithium aluminium tetrahydride In diethyl ether for 1h; Ambient temperature;94%
With lithium aluminium tetrahydride In diethyl ether 1.) 1 h, 0 deg C, 2.) 4 h, room temperature;86%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

ortho-nitrofluorobenzene
1493-27-2

ortho-nitrofluorobenzene

diethyl 2-nitrophenyl(2-propenyl)malonate

diethyl 2-nitrophenyl(2-propenyl)malonate

Conditions
ConditionsYield
With triethylsilane; t-Bu-P4 In hexane; N,N-dimethyl-formamide at 80℃; for 2h;95%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

guanidine hydrochloride
50-01-1

guanidine hydrochloride

5-allyl-2-aminopyrimidine-4,6-diol
97570-29-1

5-allyl-2-aminopyrimidine-4,6-diol

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester; guanidine hydrochloride With sodium In ethanol at 20℃; for 4h; Inert atmosphere;
Stage #2: In ethanol for 1h; Inert atmosphere; Reflux;
95%
With sodium In ethanol Inert atmosphere;95%
With sodium methylate In methanol at 0℃; Reflux;62.8%
With sodium carbonate In water at 60℃; for 0.5h; Reagent/catalyst; Sonication;61%
Stage #1: guanidine hydrochloride With sodium ethanolate In ethanol at 0℃; for 0.166667h;
Stage #2: (2-propenyl)propanedioic acid diethyl ester In ethanol at 0 - 20℃; for 65h;
Stage #3: With hydrogenchloride In ethanol; water
51%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

diethyl 2-allyl-2-((Z)-2-bromo-2-butenyl)malonate
1254219-12-9

diethyl 2-allyl-2-((Z)-2-bromo-2-butenyl)malonate

Conditions
ConditionsYield
With sodium ethanolate In tetrahydrofuran at 20℃; Inert atmosphere;95%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

(E)-(2,3-dibromoprop-1-enyl)benzene
21003-54-3, 23970-90-3, 96725-21-2

(E)-(2,3-dibromoprop-1-enyl)benzene

diethyl 2-allyl-2-((E)-3-phenyl-2-bromo-2-propenyl)malonate
1254219-14-1

diethyl 2-allyl-2-((E)-3-phenyl-2-bromo-2-propenyl)malonate

Conditions
ConditionsYield
With sodium ethanolate In tetrahydrofuran at 20℃; Inert atmosphere;95%
penta-2,3-dien-1-yl methanesulfonate

penta-2,3-dien-1-yl methanesulfonate

(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

diethyl 2-allyl-2-(penta-2,3-dien-1-yl)malonate
1304145-47-8

diethyl 2-allyl-2-(penta-2,3-dien-1-yl)malonate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere;
Stage #2: penta-2,3-dien-1-yl methanesulfonate In tetrahydrofuran; mineral oil at 21 - 25℃; Inert atmosphere;
95%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: penta-2,3-dien-1-yl methanesulfonate In tetrahydrofuran at 0 - 55℃; for 50.0833h;
40%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

diethyl propylmalonate
2163-48-6

diethyl propylmalonate

Conditions
ConditionsYield
With platinum(IV) oxide; hydrogen In ethanol at 20℃; for 4h;94%
With hydrogen; polymeric rhodium In tetrahydrofuran; ethanol under 760 Torr; for 12h;
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

1-bromooct-2-yne
18495-27-7

1-bromooct-2-yne

(2-octynyl)-(2-propenyl)propanedioic acid diethyl ester
350248-68-9

(2-octynyl)-(2-propenyl)propanedioic acid diethyl ester

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;94%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 0 - 20℃;
Stage #2: 1-bromooct-2-yne In tetrahydrofuran at 20℃; for 16h; Further stages.;
81%
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

1-bromo-3-phenylprop-2-yne
1794-48-5

1-bromo-3-phenylprop-2-yne

diethyl 2-allyl-2-(3-phenylprop-2-yn-1-yl)malonate
143633-91-4

diethyl 2-allyl-2-(3-phenylprop-2-yn-1-yl)malonate

Conditions
ConditionsYield
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 20℃;
Stage #2: 1-bromo-3-phenylprop-2-yne In tetrahydrofuran at 20℃; for 12h; Further stages.;
94%
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 1.5h; Inert atmosphere;
Stage #2: 1-bromo-3-phenylprop-2-yne In tetrahydrofuran; mineral oil at 0 - 20℃; for 24h; Inert atmosphere;
79%
With sodium hydride Inert atmosphere;
Stage #1: (2-propenyl)propanedioic acid diethyl ester With sodium hydride In tetrahydrofuran at 0 - 20℃; for 1.5h;
Stage #2: 1-bromo-3-phenylprop-2-yne In tetrahydrofuran at 0 - 20℃;
(2-propenyl)propanedioic acid diethyl ester
2049-80-1

(2-propenyl)propanedioic acid diethyl ester

(E)-1,1,1-trifluoro-4-phenylbut-3-en-2-yl benzoate

(E)-1,1,1-trifluoro-4-phenylbut-3-en-2-yl benzoate

(S)-diethyl 2-allyl-2-(4,4,4-trifluoro-1-phenylbut-2-en-1-yl)malonate

(S)-diethyl 2-allyl-2-(4,4,4-trifluoro-1-phenylbut-2-en-1-yl)malonate

Conditions
ConditionsYield
With N,O-bis-(trimethylsilyl)-acetamide; {(η4-1,5-cyclooctadiene)Pd(η3-allyl)}BF4; 1,1′-binaphthalene-2,2′-diylbis[bis(4-methylphenyl)phosphine] In 1,4-dioxane at 60℃; for 24h; Inert atmosphere; enantioselective reaction;94%

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